Research Topics
| John P RedrobeSummaryAffiliation: NeuroSearch A/S Country: Denmark Publications
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Detail Information
Publications
Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in miceJohn P Redrobe
Department of Affective Disorders, Neurosearch A S, Pederstrupvej 93, 2750 Ballerup, Denmark
Eur J Pharmacol 602:58-65. 2009..In conclusion, the present data support the idea that alpha7 nicotinic acetylcholine receptors may represent an interesting target for the treatment of conditions associated with attentional/working memory dysfunction...
Subtype-selective nicotinic acetylcholine receptor agonists enhance the responsiveness to citalopram and reboxetine in the mouse forced swim testJesper T Andreasen
Department of Affective Disorders, Neurosearch A S, Ballerup, Denmark
J Psychopharmacol 25:1347-56. 2011....
Nicotine, but not mecamylamine, enhances antidepressant-like effects of citalopram and reboxetine in the mouse forced swim and tail suspension testsJesper T Andreasen
Department of Affective Disorders, Neurosearch A S, 93 Pederstrupvej, DK 2750 Ballerup, Denmark
Behav Brain Res 197:150-6. 2009....
Chronic oral nicotine increases brain [3H]epibatidine binding and responsiveness to antidepressant drugs, but not nicotine, in the mouse forced swim testJesper T Andreasen
Department of Affective Disorders, Neurosearch A S, 93 Pederstrupvej, 2750 Ballerup, Denmark
Psychopharmacology (Berl) 205:517-28. 2009..In mice, acute nicotine administration enhances the activity of antidepressants in the mouse forced swim (mFST) and tail suspension tests. Here, we investigated if this action of nicotine is also reflected in a chronic treatment regimen...
alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatmentMorten S Thomsen
Department of Translational Neurobiology, Neurosearch A S, Ballerup, Denmark
Neuropharmacology 56:1001-9. 2009....
Effects of neuronal Kv7 potassium channel activators on hyperactivity in a rodent model of maniaJohn P Redrobe
Department of Affective Disorders, Neurosearch A S, Pederstrupvej 93, 2750 Ballerup, Denmark
Behav Brain Res 198:481-5. 2009..It is imperative that relevant control studies (AMPH- and CDP-alone) be incorporated and reported routinely to enable thorough interpretation of data generated by means of this behavioural test...
Antidepressant-like effects of nicotine and mecamylamine in the mouse forced swim and tail suspension tests: role of strain, test and sexJesper T Andreasen
Department of Affective Disorders, NeuroSearch, Ballerup, Denmark
Behav Pharmacol 20:286-95. 2009..Nicotine was devoid of effects in the mTST, except in female C57BL/6J mice, where it increased immobility. We hypothesize that nicotine and mecamylamine produce antidepressant-like effects through partially different mechanisms...
