Research Topics
Genomes and GenesSpecies | David ErritzoeSummaryAffiliation: Neurobiology Research Unit Country: Denmark Publications
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Detail Information
Publications
Cortical and subcortical 5-HT2A receptor binding in neuroleptic-naive first-episode schizophrenic patientsDavid Erritzoe
Neurobiology Research Unit, Center for Integrated Molecular Brain Imaging, University Hospital Rigshospitalet, Copenhagen, Denmark
Neuropsychopharmacology 33:2435-41. 2008..However, a preliminary finding of increased 5-HT(2A) binding in the caudate nucleus requires further investigation to explore the relation of subcortical and cortical 5-HT(2A) receptor binding...- Cerebral serotonin transporter binding is inversely related to body mass indexD Erritzoe
Neurobiology Research Unit, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark
Neuroimage 52:284-9. 2010.... - Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol useD Erritzoe
Neurobiology Research Unit, University Hospital Rigshospitalet, Copenhagen, Denmark
Neuroimage 46:23-30. 2009..We suggest that our observation is driven by a lower central 5-HT level in overweight people, leading both to increased food intake and to a compensatory upregulation of cerebral 5-HT(2A) receptor density... - A nonlinear relationship between cerebral serotonin transporter and 5-HT(2A) receptor binding: an in vivo molecular imaging study in humansDavid Erritzoe
Neurobiology Research Unit and PET and Cyclotron Unit, University Hospital Rigshospitalet, Copenhagen, Denmark
J Neurosci 30:3391-7. 2010..That is, the observed association between the 5-HT(2A) receptor and SERT binding could be driven by the projection output from the raphe nuclei, but other explanations are also at hand... 
Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levelsAnders Bue Klein
Neurobiology Research Unit, The Neuroscience Center, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
J Cereb Blood Flow Metab 30:e1-7. 2010..In conclusion, val66met BDNF polymorphism status is not associated with changes in the serotonergic system. Moreover, BDNF levels in blood do not correlate with either 5-HT(2A) or SERT binding...- In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen usersDavid Erritzoe
Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Arch Gen Psychiatry 68:562-76. 2011..In addition, MDMA is a potent releaser and reuptake inhibitor of presynaptic serotonin... - Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor bindingVibe G Frokjaer
Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Copenhagen, Denmark
Psychoneuroendocrinology 35:1311-20. 2010..This study was undertaken to examine if baseline levels of endogenous sex hormones are associated with cerebral serotonin 2A (5-HT(2A)) receptor binding in men... - The personality trait openness is related to cerebral 5-HTT levelsJan Kalbitzer
Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Denmark
Neuroimage 45:280-5. 2009..We speculate that the set-point of serotonergic signaling in an individual represents a trade-off between flexibility and vulnerability when exposed to environmental stress... - Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapineHans Rasmussen
Center for Neuropsychiatric Schizophrenia Research, Faculty of Health Sciences, Copenhagen University Hospital Glostrup, Copenhagen, Denmark
Psychopharmacology (Berl) 213:583-92. 2011.... - Seasonal changes in brain serotonin transporter binding in short serotonin transporter linked polymorphic region-allele carriers but not in long-allele homozygotesJan Kalbitzer
Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Biol Psychiatry 67:1033-9. 2010..A polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) has been associated with seasonality both in patients with seasonal affective disorder and in the general population... - Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjectsKarine Madsen
The Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Psychopharmacology (Berl) 213:573-81. 2011..We hypothesized that higher performance on tests sensitive to serotonin would be associated with higher SERT levels in specific fronto-striatal brain regions... - Simultaneous polysubstance use among Danish 3,4-methylenedioxymethamphetamine and hallucinogen users: combination patterns and proposed biological basesCecilie L Licht
Neurobiology Research Unit NRU and Center for Integrated Molecular Brain Imaging Cimbi, University of Copenhagen and Rigshospitalet, Copenhagen, Denmark
Hum Psychopharmacol 27:352-63. 2012..To describe patterns of simultaneous polysubstance use (SPU) among Danish 3,4-methylenedioxymethamphetamine (MDMA) ("Ecstasy") and hallucinogen users... - A probabilistic approach to delineating functional brain regionsJan Kalbitzer
Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark
J Nucl Med Technol 37:91-5. 2009..The case is made for the raphé nuclei, a collection of nuclei situated in the brain stem known to be densely packed with serotonin transporters (5-hydroxytryptaminic [5-HTT] system)... - Serotonin transporter binding in the hypothalamus correlates negatively with tonic heat pain ratings in healthy subjects: a [11C]DASB PET studyRon Kupers
Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Neuroimage 54:1336-43. 2011..The negative correlation between SERT binding in the hypothalamus and insula with tonic pain ratings suggests a possible serotonergic control of the role of these areas in the modulation or in the affective appreciation of pain... - Familial risk for mood disorder and the personality risk factor, neuroticism, interact in their association with frontolimbic serotonin 2A receptor bindingVibe G Frokjaer
Neurobiology Research Unit and Center for Integrated Molecular Brain Imaging, Denmark
Neuropsychopharmacology 35:1129-37. 2010.... - High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter bindingVibe G Frokjaer
Neurobiology Research Unit and Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Denmark
Neuroimage 46:360-6. 2009..In conclusion, our data suggest that a low SERT binding in dorsolateral prefrontal cortex represents a trait marker for mood disorders... - Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PETLisbeth Marner
The Neuroscience Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen O, Denmark
Neuroimage 50:855-61. 2010..In conclusion, the 5-HT(4) receptor binding in human brain can be reliably assessed with [(11)C]SB207145, which is encouraging for future PET studies of drug occupancy or patients with neuropsychiatric disorders... - Serotonin 2A Receptors, Citalopram and Tryptophan-Depletion: a Multimodal Imaging Study of their Interactions During Response InhibitionJulian Macoveanu
1 Danish Research Centre for MR, Copenhagen University Hospital, Hvidovre, Denmark 2 Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark
Neuropsychopharmacology 38:996-1005. 2013..These links between serotonergic function and response inhibition in healthy subjects may help to interpret serotonergic abnormalities underlying impulsivity in neuropsychiatric disorders...