Karin Sørig Hougaard

Summary

Affiliation: National Research Centre for the Working Environment
Country: Denmark

Publications

  1. ncbi request reprint Socio-occupational class, region of birth and maternal age: influence on time to detection of cryptorchidism (undescended testes): a Danish nationwide register study
    Karin Sørig Hougaard
    The National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    BMC Urol 14:23. 2014
  2. doi request reprint Effects of lung exposure to carbon nanotubes on female fertility and pregnancy. A study in mice
    Karin S Hougaard
    National Research Centre for the Working Environment, Copenhagen Ø, Denmark
    Reprod Toxicol 41:86-97. 2013
  3. pmc Testing the association between psychosocial job strain and adverse birth outcomes--design and methods
    Ann D Larsen
    National Research Centre for the Working Environment, Copenhagen, Denmark
    BMC Public Health 11:255. 2011
  4. doi request reprint Gestational chronic mild stress: effects on acoustic startle in male offspring of rats
    K S Hougaard
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen Ø, Denmark
    Int J Dev Neurosci 29:495-500. 2011
  5. pmc Effects of prenatal exposure to surface-coated nanosized titanium dioxide (UV-Titan). A study in mice
    Karin S Hougaard
    National Research Centre for the Working Environment, Copenhagen Ø, Denmark
    Part Fibre Toxicol 7:16. 2010
  6. doi request reprint Increased incidence of infertility treatment among women working in the plastics industry
    Karin S Hougaard
    National Research Centre for the Working Environment, DK 2100 Copenhagen, Denmark
    Reprod Toxicol 27:186-9. 2009
  7. doi request reprint Infertility among women working in horticulture. A follow-up study in the Danish Occupational Hospitalization Register
    Karin Sørig Hougaard
    National Research Centre for the Working Environment, Copenhagen, Denmark
    Fertil Steril 91:1385-7. 2009
  8. pmc Effects of prenatal exposure to diesel exhaust particles on postnatal development, behavior, genotoxicity and inflammation in mice
    Karin S Hougaard
    National Research Centre of the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen Ø, Denmark
    Part Fibre Toxicol 5:3. 2008
  9. ncbi request reprint No evidence for enhanced noise induced hearing loss after prenatal stress or dexamethasone
    Karin S Hougaard
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    Neurotoxicol Teratol 29:613-21. 2007
  10. doi request reprint Daily sperm production: application in studies of prenatal exposure to nanoparticles in mice
    Zdenka Orabi Kyjovska
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen Ø, Denmark
    Reprod Toxicol 36:88-97. 2013

Detail Information

Publications23

  1. ncbi request reprint Socio-occupational class, region of birth and maternal age: influence on time to detection of cryptorchidism (undescended testes): a Danish nationwide register study
    Karin Sørig Hougaard
    The National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    BMC Urol 14:23. 2014
    ..Here we assess the influence of socio-occupational class, geographical region, maternal age and birth cohort on time to detection and correction of cryptorchidism...
  2. doi request reprint Effects of lung exposure to carbon nanotubes on female fertility and pregnancy. A study in mice
    Karin S Hougaard
    National Research Centre for the Working Environment, Copenhagen Ø, Denmark
    Reprod Toxicol 41:86-97. 2013
    ..Exposure was not associated with changes in the assessed gestational or offspring parameters. ..
  3. pmc Testing the association between psychosocial job strain and adverse birth outcomes--design and methods
    Ann D Larsen
    National Research Centre for the Working Environment, Copenhagen, Denmark
    BMC Public Health 11:255. 2011
    ..In the present protocol, we aim to examine if work characterised by high demands and low control, during pregnancy, is associated with the risk of giving birth to a child born preterm or small for gestational age...
  4. doi request reprint Gestational chronic mild stress: effects on acoustic startle in male offspring of rats
    K S Hougaard
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen Ø, Denmark
    Int J Dev Neurosci 29:495-500. 2011
    ..The present work supports the hypothesis that the maternal environment is a long-term determinant of phenotypic differences in sensitivity to stressors...
  5. pmc Effects of prenatal exposure to surface-coated nanosized titanium dioxide (UV-Titan). A study in mice
    Karin S Hougaard
    National Research Centre for the Working Environment, Copenhagen Ø, Denmark
    Part Fibre Toxicol 7:16. 2010
    ..Consequently, also toxicological properties may change compared to the parent compound. We examined developmental and neurobehavioral effects following maternal exposure to a nanoparticulate UV-filter (UV-titan L181)...
  6. doi request reprint Increased incidence of infertility treatment among women working in the plastics industry
    Karin S Hougaard
    National Research Centre for the Working Environment, DK 2100 Copenhagen, Denmark
    Reprod Toxicol 27:186-9. 2009
    ..9 cases, with relative risk being 0.82 (95% CI: 0.59-1.11). The increased incidence of infertility treatment in female plastics workers motivates more specific studies of reproductive occupational health in the plastics industry...
  7. doi request reprint Infertility among women working in horticulture. A follow-up study in the Danish Occupational Hospitalization Register
    Karin Sørig Hougaard
    National Research Centre for the Working Environment, Copenhagen, Denmark
    Fertil Steril 91:1385-7. 2009
    ..84-1.32) for treatment of infertility in women working in horticulture compared with the standard population and did not confirm that women working in the horticultural industry are at increased risk for infertility...
  8. pmc Effects of prenatal exposure to diesel exhaust particles on postnatal development, behavior, genotoxicity and inflammation in mice
    Karin S Hougaard
    National Research Centre of the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen Ø, Denmark
    Part Fibre Toxicol 5:3. 2008
    ..abstract:..
  9. ncbi request reprint No evidence for enhanced noise induced hearing loss after prenatal stress or dexamethasone
    Karin S Hougaard
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    Neurotoxicol Teratol 29:613-21. 2007
    ..However, hearing may be modulated by prenatal stressors under certain circumstances, of which the timing and degree are probably the most important...
  10. doi request reprint Daily sperm production: application in studies of prenatal exposure to nanoparticles in mice
    Zdenka Orabi Kyjovska
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen Ø, Denmark
    Reprod Toxicol 36:88-97. 2013
    ..F2 offspring, whose fathers were prenatally exposed to Printex90, showed lowered sperm production. Furthermore, we report statistically significant differences in sperm production between mouse strains...
  11. doi request reprint Maternal inhalation of surface-coated nanosized titanium dioxide (UV-Titan) in C57BL/6 mice: effects in prenatally exposed offspring on hepatic DNA damage and gene expression
    Petra Jackson
    National Research Centre for the Working Environment, DK 2100 Copenhagen Ø, Denmark
    Nanotoxicology 7:85-96. 2013
    ..Changes may be a secondary response to maternal inflammation although no direct link was evident through gene expression analysis...
  12. pmc Particle-induced pulmonary acute phase response correlates with neutrophil influx linking inhaled particles and cardiovascular risk
    Anne Thoustrup Saber
    The National Research Centre for the Working Environment, Copenhagen, Denmark
    PLoS ONE 8:e69020. 2013
    ..Acute phase response is causally linked to cardiovascular disease. Here, we propose that particle-induced pulmonary acute phase response provides an underlying mechanism for particle-induced cardiovascular risk...
  13. pmc Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: effects on liver DNA strand breaks in dams and offspring
    Petra Jackson
    National Research Centre for the Working Environment, Copenhagen, Denmark
    Nanotoxicology 6:486-500. 2012
    ..Neither inhalation nor instillation affected gestation and lactation. Maternal inhalation exposure to Printex 90-induced liver DNA damage in the mothers and the in utero exposed offspring...
  14. doi request reprint In utero exposure to nanosized carbon black (Printex90) does not induce tandem repeat mutations in female murine germ cells
    Anne Mette Zenner Boisen
    National Research Centre for the Working Environment, DK 2100 Copenhagen, Denmark
    Reprod Toxicol 41:45-8. 2013
    ..ESTR mutation rates in CB-exposed F2 female offspring were not statistically different from those of F2 female control offspring. ..
  15. pmc NanoTIO(2) (UV-Titan) does not induce ESTR mutations in the germline of prenatally exposed female mice
    Anne Mette Zenner Boisen
    The National Research Centre for the Working Environment, Copenhagen, Denmark
    Part Fibre Toxicol 9:19. 2012
    ..Here we investigate the effects of nanoparticles on the female germline. Since pulmonary exposure to nanosized titanium dioxide (nanoTiO(2)) produces a long-lasting inflammatory response in mice, it was chosen for the present study...
  16. doi request reprint Prenatal exposure to diesel exhaust particles and effect on the male reproductive system in mice
    Jette Gjerke Hemmingsen
    Section of Environmental Health, Department of Public Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    Toxicology 264:61-8. 2009
    ..In conclusion, prenatal exposure to SRM2975 was associated with reduced daily sperm production in adulthood, which was not possible to clearly associate with altered endocrine function or expression of aquaporins in the testes...
  17. ncbi request reprint Effects of combined prenatal stress and toluene exposure on apoptotic neurodegeneration in cerebellum and hippocampus of rats
    Ole Ladefoged
    Institute of Food Safety and Nutrition, Danish Veterinary and Food Administration, Copenhagen, Denmark
    Basic Clin Pharmacol Toxicol 94:169-76. 2004
    ..New methods to quantitate the relative level of apoptosis measured as DNA-laddering and the caspase-3 activity in tissue are presented...
  18. doi request reprint Industrial differences in female fertility treatment rates--a new approach to assess differences related to occupation?
    Helene Feveile
    National Research Centre for the Working Environment, Copenhagen, Denmark
    Scand J Public Health 39:164-71. 2011
    ..Several exposures in the work environment have been hypothesized to affect female reproduction. This study aimed to estimate relative rates (RR) of female fertility treatment in the 57 industrial groups in Denmark...
  19. ncbi request reprint Effects of prenatal exposure to chronic mild stress and toluene in rats
    Karin S Hougaard
    National Institute of Occupational Health, DK 2100 Copenhagen Ø, Denmark
    Neurotoxicol Teratol 27:153-67. 2005
    ..However, the effects of prenatal CMS indicate that stress during fetal life may interfere with the development of the thymus and increase the reactivity (startle reflex) of the offspring...
  20. ncbi request reprint Prenatal stress may increase vulnerability to life events: comparison with the effects of prenatal dexamethasone
    Karin S Hougaard
    National Institute of Occupational Health, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    Brain Res Dev Brain Res 159:55-63. 2005
    ..The prenatal environment may thus form part of the explanation of the considerable individual variation in the development of psychopathology...
  21. ncbi request reprint Toluene depresses plasma corticosterone in pregnant rats
    Karin S Hougaard
    National Institute of Occupational Health, Copenhagen Ø, Denmark
    Pharmacol Toxicol 92:148-52. 2003
    ....
  22. ncbi request reprint Enhancement of developmental toxicity effects of chemicals by gestational stress. A review
    Karin S Hougaard
    Laboratory National Research Centre for the Working Environment, DK 2100 Copenhagen Ø, Denmark
    Neurotoxicol Teratol 29:425-45. 2007
    ..Interactive response seems to depend on stressor severity and timing of chemical exposure relative to maternal stress which should be further scrutinized...
  23. ncbi request reprint Changes in markers of oxidative stress and membrane properties in synaptosomes from rats exposed prenatally to toluene
    Sven Edelfors
    Department of Pharmacology, Panum Institute, University of Copenhagen, Denmark
    Pharmacol Toxicol 90:26-31. 2002
    ..in vitro but the change in fluidity was identical in both groups of offspring. The results indicate that prenatal exposure to toluene induces long-lasting changes in oxidative status and membrane function...