Research Topics
| Nils KnudsenSummaryCountry: Denmark Publications
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Detail Information
Publications
Iodine intake and incidence of thyroid cancer in DenmarkThomas Sehestedt
Department of Internal Medicine, Glostrup Hospital, Nordre Ringvej 57, 2600 Glostrup, Denmark
Clin Endocrinol (Oxf) 65:229-33. 2006..The objective of the study was to determine whether the incidence of thyroid cancer differs between these two regions, as any difference would have important safety implications for the national iodine supplementation programme...- Risk factors for benign thyroid diseaseNils Knudsen
Medical Department B, H:S Bispebjerg Hospital, Copenhagen, Denmark
Dan Med Bull 52:160-85. 2005 - Low goitre prevalence among users of oral contraceptives in a population sample of 3712 womenNils Knudsen
Department of Internal Medicine, Bispebjerg Hospital, Copenhagen, Denmark
Clin Endocrinol (Oxf) 57:71-6. 2002..This is supported by experimental data, but a recent population study suggested decreased thyroid volumes among users of OC... - Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the populationNils Knudsen
Endocrine Unit, Medical Clinic I, Bispebjerg Hospital, Copenhagen, Denmark
J Clin Endocrinol Metab 90:4019-24. 2005..Few data have been presented regarding an association between variations in thyroid function seen in the general population and body weight... 
Lower prevalence of mild hyperthyroidism related to a higher iodine intake in the population: prospective study of a mandatory iodization programmePernille Vejbjerg
Department of Endocrinology and Gastroenterology, Bispebjerg University Hospital, Copenhagen, Denmark
Clin Endocrinol (Oxf) 71:440-5. 2009..We evaluated the influence of a higher iodine intake on thyroid hormone levels and the prevalence of thyroid dysfunction in the Danish population...- Association of tobacco smoking with goiter in a low-iodine-intake areaNils Knudsen
Danish Centre for Prevention of Thyroid Diseases DanThyr, Glostrup University Hospital, Copenhagen, Denmark
Arch Intern Med 162:439-43. 2002..Goiter development depends on genetic and environmental factors. The major environmental factor is iodine intake, whereas diverging results have been published concerning the association between smoking and goiter... - Effect of a mandatory iodization program on thyroid gland volume based on individuals' age, gender, and preceding severity of dietary iodine deficiency: a prospective, population-based studyPernille Vejbjerg
Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Denmark
J Clin Endocrinol Metab 92:1397-401. 2007..We aimed to evaluate prospectively the effect of 4 yr of mandatory iodization of salt (13 ppm iodine) on thyroid volume in two regional areas with respectively mild and moderate iodine deficiency... - The association between hypoechogenicity or irregular echo pattern at thyroid ultrasonography and thyroid function in the general populationPernille Vejbjerg
Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark
Eur J Endocrinol 155:547-52. 2006..The aim of this study was to investigate the association between echogenicity of the thyroid/irregular echo pattern, and thyroid function in the general population, i.e. subjects without overt thyroid disease... - Parity is associated with increased thyroid volume solely among smokers in an area with moderate to mild iodine deficiencyNils Knudsen
Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen, Denmark
Eur J Endocrinol 146:39-43. 2002..We investigated the association between parity and thyroid volume and a possible impact of iodine deficiency and tobacco smoking on this association... - Risk factors for goiter and thyroid nodulesNils Knudsen
Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Denmark
Thyroid 12:879-88. 2002..The difference in age maximum in goiter prevalence suggests that monitoring of iodine deficiency disorders should ideally include a spectrum of age groups... - The impact of smoking on thyroid volume and function in relation to a shift towards iodine sufficiencyPernille Vejbjerg
Department of Endocrinology and Gastroenterology, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400, Copenhagen NV, Denmark
Eur J Epidemiol 23:423-9. 2008..The effect of smoking on hormonal level was unchanged after the iodization. Thus the effect of smoking on thyroid volume seems to be dependent on iodine intake, whereas the effect on function seems mainly to depend on other factors... - An increased incidence of overt hypothyroidism after iodine fortification of salt in Denmark: a prospective population studyInge Bülow Pedersen
Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
J Clin Endocrinol Metab 92:3122-7. 2007..We prospectively identified all new cases of overt hypothyroidism in two areas of Denmark before and for the first 7 yr after IF had been introduced... - The Danish investigation on iodine intake and thyroid disease, DanThyr: status and perspectivesPeter Laurberg
Department of Endocrinology and Medicine, Aalborg Hospital, DK 9000 Aalborg, Denmark
Eur J Endocrinol 155:219-28. 2006..p.m. iodine) was initiated in 2000/2001. The Danish investigation on iodine intake and thyroid disease (DanThyr) is the monitoring of the iodine fortification program... - Increase in incidence of hyperthyroidism predominantly occurs in young people after iodine fortification of salt in DenmarkInge Bülow Pedersen
Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
J Clin Endocrinol Metab 91:3830-4. 2006..We prospectively registered all new cases of overt hyperthyroidism in two areas of Denmark before and for the first 6 yr after iodine fortification... - Use of dietary supplements in Denmark is associated with health and former smokingVibeke K Knudsen
Institute of Food Research and Nutrition, Danish Veterinary and Food Administration, Søborg, Denmark
Public Health Nutr 5:463-8. 2002..To describe the use of dietary supplements in a group of Danish adults and to investigate the differences between users and non-users with respect to age, gender, health and lifestyle factors... - Lack of association between thyroid autoantibodies and parity in a population study argues against microchimerism as a trigger of thyroid autoimmunityInge Bülow Pedersen
Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
Eur J Endocrinol 154:39-45. 2006..It has also been suggested that foetal microchimerism involving transfer of foetal cells into maternal tissue during pregnancy may play an important role... - Epidemiology of subtypes of hypothyroidism in DenmarkAllan Carlé
Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
Eur J Endocrinol 154:21-8. 2006..We therefore studied incidences of subtypes of primary, overt hypothyroidism in a Danish population cohort and compared incidences in two subcohorts with different levels of iodine intake... - Thyroid peroxidase and thyroglobulin autoantibodies in a large survey of populations with mild and moderate iodine deficiencyInge Bülow Pedersen
Department of Endocrinology and Medicine, Aalborg Hospital, Denmark
Clin Endocrinol (Oxf) 58:36-42. 2003..In the present study we evaluated if TPO-Ab and Tg-Ab tend to develop in parallel or whether one or the other may be more prevalent in subsets of the population... - A population study of the association between thyroid autoantibodies in serum and abnormalities in thyroid function and structureInge Bülow Pedersen
Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Denmark
Clin Endocrinol (Oxf) 62:713-20. 2005..The aims of this study were to evaluate the association between thyroid autoantibodies in serum and abnormalities in thyroid function and structure, and to study the thyroid volume in subjects with subclinical autoimmune hypothyroidism... - Humic substances in drinking water and the epidemiology of thyroid diseasePeter Laurberg
Department of Endocrinology and Medicine, University Hospital Aalborg, Denmark
Biofactors 19:145-53. 2003..The effect of humic substances in drinking water on the epidemiology of thyroid disease probably depends on the source of aquifer sediments... - Relations between various measures of iodine intake and thyroid volume, thyroid nodularity, and serum thyroglobulinLone B Rasmussen
Institute of Food Research and Nutrition, The Danish Veterinary and Food Administration, Søborg, Denmark
Am J Clin Nutr 76:1069-76. 2002..Iodine intake can be measured in various ways, and each method may have advantages and disadvantages... - Large differences in incidences of overt hyper- and hypothyroidism associated with a small difference in iodine intake: a prospective comparative register-based population surveyInge Bülow Pedersen
Department of Endocrinology and Medicine, Aalborg Hospital, DK 9000 Aalborg, Denmark
J Clin Endocrinol Metab 87:4462-9. 2002..The optimal level of iodine intake to prevent thyroid disease may be a relatively narrow range around the recommended daily iodine intake of 150 micro g... - Dietary iodine intake and urinary iodine excretion in a Danish population: effect of geography, supplements and food choiceLone B Rasmussen
Institute of Food Research and Nutrition, Danish Veterinary and Food Administration, Søborg, Denmark
Br J Nutr 87:61-9. 2002..Even individuals who followed the advice regarding intake of 200-300 g fish/week and 0.5 litres milk/d had an intake below the recommended level if living in Aalborg... - Age modifies the pituitary TSH response to thyroid failureAllan Carlé
Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Denmark
Thyroid 17:139-44. 2007..To investigate the association between serum TSH, total T4 and various patient characteristics when hypothyroidism is diagnosed in a population, and to study how age, sex and serum T4 levels influenced pituitary TSH response... - Smoking is negatively associated with the presence of thyroglobulin autoantibody and to a lesser degree with thyroid peroxidase autoantibody in serum: a population studyInge Bülow Pedersen
Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
Eur J Endocrinol 158:367-73. 2008..The knowledge of a possible association between lifestyle factors and circulating thyroid antibodies is limited... - Thiocyanate in food and iodine in milk: from domestic animal feeding to improved understanding of cretinismPeter Laurberg
Department of Endocrinology and Medicine, Aalborg Hospital, Aalborg, Denmark
Thyroid 12:897-902. 2002..It can be speculated that a low-iodine content of mother's milk because of inhibition of NIS in the mammary gland may be one factor of importance for development of myxedematous cretinism... - Surveyance of disease frequency in a population by linkage to diagnostic laboratory databases. A system for monitoring the incidences of hyper- and hypothyroidism as part of the Danish iodine supplementation programInge Bülow Pedersen
Department of Endocrinology and Medicine, Aalborg Hospital, Reberbansgade, DK 9000 Aalborg, Denmark
Comput Methods Programs Biomed 67:209-16. 2002..In Denmark an increase in iodine intake through salt iodization has been introduced in 1998. In parallel a program for surveyance of thyroid diseases in the population was developed as recommended by UNICEF and WHO...