Nils Knudsen

Summary

Country: Denmark

Publications

  1. ncbi request reprint Iodine intake and incidence of thyroid cancer in Denmark
    Thomas Sehestedt
    Department of Internal Medicine, Glostrup Hospital, Nordre Ringvej 57, 2600 Glostrup, Denmark
    Clin Endocrinol (Oxf) 65:229-33. 2006
  2. ncbi request reprint Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population
    Nils Knudsen
    Endocrine Unit, Medical Clinic I, Bispebjerg Hospital, Copenhagen, Denmark
    J Clin Endocrinol Metab 90:4019-24. 2005
  3. ncbi request reprint Risk factors for benign thyroid disease
    Nils Knudsen
    Medical Department B, H S Bispebjerg Hospital, Copenhagen, Denmark
    Dan Med Bull 52:160-85. 2005
  4. ncbi request reprint Low goitre prevalence among users of oral contraceptives in a population sample of 3712 women
    Nils Knudsen
    Department of Internal Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Clin Endocrinol (Oxf) 57:71-6. 2002
  5. doi request reprint Lower prevalence of mild hyperthyroidism related to a higher iodine intake in the population: prospective study of a mandatory iodization programme
    Pernille Vejbjerg
    Department of Endocrinology and Gastroenterology, Bispebjerg University Hospital, Copenhagen, Denmark
    Clin Endocrinol (Oxf) 71:440-5. 2009
  6. ncbi request reprint Association of tobacco smoking with goiter in a low-iodine-intake area
    Nils Knudsen
    Danish Centre for Prevention of Thyroid Diseases DanThyr, Glostrup University Hospital, Copenhagen, Denmark
    Arch Intern Med 162:439-43. 2002
  7. ncbi request reprint The association between hypoechogenicity or irregular echo pattern at thyroid ultrasonography and thyroid function in the general population
    Pernille Vejbjerg
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark
    Eur J Endocrinol 155:547-52. 2006
  8. ncbi request reprint Effect of a mandatory iodization program on thyroid gland volume based on individuals' age, gender, and preceding severity of dietary iodine deficiency: a prospective, population-based study
    Pernille Vejbjerg
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Denmark
    J Clin Endocrinol Metab 92:1397-401. 2007
  9. ncbi request reprint Parity is associated with increased thyroid volume solely among smokers in an area with moderate to mild iodine deficiency
    Nils Knudsen
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen, Denmark
    Eur J Endocrinol 146:39-43. 2002
  10. ncbi request reprint A cautious iodization programme bringing iodine intake to a low recommended level is associated with an increase in the prevalence of thyroid autoantibodies in the population
    Inge B Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, AalborgEndocrine Unit, Medical Clinic I, Bispebjerg Hospital, CopenhagenResearch Centre for Prevention and Health, Glostrup University Hospital, GlostrupFaculty of Health Science, University of Copenhagen, CopenhagenDepartment of Gastroenterology, Slagelse Hospital, SlagelseDivision of Nutrition, National Food Institute, Copenhagen, Denmark
    Clin Endocrinol (Oxf) 75:120-6. 2011

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Iodine intake and incidence of thyroid cancer in Denmark
    Thomas Sehestedt
    Department of Internal Medicine, Glostrup Hospital, Nordre Ringvej 57, 2600 Glostrup, Denmark
    Clin Endocrinol (Oxf) 65:229-33. 2006
    ..The objective of the study was to determine whether the incidence of thyroid cancer differs between these two regions, as any difference would have important safety implications for the national iodine supplementation programme...
  2. ncbi request reprint Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population
    Nils Knudsen
    Endocrine Unit, Medical Clinic I, Bispebjerg Hospital, Copenhagen, Denmark
    J Clin Endocrinol Metab 90:4019-24. 2005
    ..Few data have been presented regarding an association between variations in thyroid function seen in the general population and body weight...
  3. ncbi request reprint Risk factors for benign thyroid disease
    Nils Knudsen
    Medical Department B, H S Bispebjerg Hospital, Copenhagen, Denmark
    Dan Med Bull 52:160-85. 2005
  4. ncbi request reprint Low goitre prevalence among users of oral contraceptives in a population sample of 3712 women
    Nils Knudsen
    Department of Internal Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Clin Endocrinol (Oxf) 57:71-6. 2002
    ..This is supported by experimental data, but a recent population study suggested decreased thyroid volumes among users of OC...
  5. doi request reprint Lower prevalence of mild hyperthyroidism related to a higher iodine intake in the population: prospective study of a mandatory iodization programme
    Pernille Vejbjerg
    Department of Endocrinology and Gastroenterology, Bispebjerg University Hospital, Copenhagen, Denmark
    Clin Endocrinol (Oxf) 71:440-5. 2009
    ..We evaluated the influence of a higher iodine intake on thyroid hormone levels and the prevalence of thyroid dysfunction in the Danish population...
  6. ncbi request reprint Association of tobacco smoking with goiter in a low-iodine-intake area
    Nils Knudsen
    Danish Centre for Prevention of Thyroid Diseases DanThyr, Glostrup University Hospital, Copenhagen, Denmark
    Arch Intern Med 162:439-43. 2002
    ..Goiter development depends on genetic and environmental factors. The major environmental factor is iodine intake, whereas diverging results have been published concerning the association between smoking and goiter...
  7. ncbi request reprint The association between hypoechogenicity or irregular echo pattern at thyroid ultrasonography and thyroid function in the general population
    Pernille Vejbjerg
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark
    Eur J Endocrinol 155:547-52. 2006
    ..The aim of this study was to investigate the association between echogenicity of the thyroid/irregular echo pattern, and thyroid function in the general population, i.e. subjects without overt thyroid disease...
  8. ncbi request reprint Effect of a mandatory iodization program on thyroid gland volume based on individuals' age, gender, and preceding severity of dietary iodine deficiency: a prospective, population-based study
    Pernille Vejbjerg
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Denmark
    J Clin Endocrinol Metab 92:1397-401. 2007
    ..We aimed to evaluate prospectively the effect of 4 yr of mandatory iodization of salt (13 ppm iodine) on thyroid volume in two regional areas with respectively mild and moderate iodine deficiency...
  9. ncbi request reprint Parity is associated with increased thyroid volume solely among smokers in an area with moderate to mild iodine deficiency
    Nils Knudsen
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen, Denmark
    Eur J Endocrinol 146:39-43. 2002
    ..We investigated the association between parity and thyroid volume and a possible impact of iodine deficiency and tobacco smoking on this association...
  10. ncbi request reprint A cautious iodization programme bringing iodine intake to a low recommended level is associated with an increase in the prevalence of thyroid autoantibodies in the population
    Inge B Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, AalborgEndocrine Unit, Medical Clinic I, Bispebjerg Hospital, CopenhagenResearch Centre for Prevention and Health, Glostrup University Hospital, GlostrupFaculty of Health Science, University of Copenhagen, CopenhagenDepartment of Gastroenterology, Slagelse Hospital, SlagelseDivision of Nutrition, National Food Institute, Copenhagen, Denmark
    Clin Endocrinol (Oxf) 75:120-6. 2011
    ..The effect of public iodization programmes on antibody prevalence is uncertain...
  11. ncbi request reprint Risk factors for goiter and thyroid nodules
    Nils Knudsen
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Denmark
    Thyroid 12:879-88. 2002
    ..The difference in age maximum in goiter prevalence suggests that monitoring of iodine deficiency disorders should ideally include a spectrum of age groups...
  12. ncbi request reprint Development of autoimmune overt hypothyroidism is highly associated with live births and induced abortions but only in premenopausal women
    Allan Carlé
    Department of Endocrinology A C, I B P, P L, Aalborg University Hospital, DK 9000 Aalborg, Denmark Endocrine Unit N K, H P, Medical Clinic I, Bispebjerg Hospital, DK 2400 Copenhagen, Denmark Department of Internal Medicine L O, Slagelse Hospital, DK 4200 Slagelse, Denmark and National Food Institute L B R, Technical University of Denmark, DK 2800 Copenhagen, Denmark
    J Clin Endocrinol Metab 99:2241-9. 2014
    ..The 1-year postpartum period is often accompanied by increased risk for thyroid disease...
  13. pmc Thyroid function and body weight: a community-based longitudinal study
    Lena Bjergved
    Research Centre for Prevention and Health, The Capital Region of Denmark, Glostrup, Denmark Department of Endocrinology, Bispebjerg University Hospital, Copenhagen, Denmark
    PLoS ONE 9:e93515. 2014
    ..However, for longitudinal data, the association is less clear. Thus, we tested the association between serum thyrotropin (TSH) and body weight in a community-based sample of adult persons followed for 11 years...
  14. ncbi request reprint Humic substances in drinking water and the epidemiology of thyroid disease
    Peter Laurberg
    Department of Endocrinology and Medicine, University Hospital Aalborg, Denmark
    Biofactors 19:145-53. 2003
    ..The effect of humic substances in drinking water on the epidemiology of thyroid disease probably depends on the source of aquifer sediments...
  15. ncbi request reprint Use of dietary supplements in Denmark is associated with health and former smoking
    Vibeke K Knudsen
    Institute of Food Research and Nutrition, Danish Veterinary and Food Administration, Søborg, Denmark
    Public Health Nutr 5:463-8. 2002
    ..To describe the use of dietary supplements in a group of Danish adults and to investigate the differences between users and non-users with respect to age, gender, health and lifestyle factors...
  16. doi request reprint The impact of smoking on thyroid volume and function in relation to a shift towards iodine sufficiency
    Pernille Vejbjerg
    Department of Endocrinology and Gastroenterology, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400, Copenhagen NV, Denmark
    Eur J Epidemiol 23:423-9. 2008
    ..The effect of smoking on hormonal level was unchanged after the iodization. Thus the effect of smoking on thyroid volume seems to be dependent on iodine intake, whereas the effect on function seems mainly to depend on other factors...
  17. ncbi request reprint An increased incidence of overt hypothyroidism after iodine fortification of salt in Denmark: a prospective population study
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 92:3122-7. 2007
    ..We prospectively identified all new cases of overt hypothyroidism in two areas of Denmark before and for the first 7 yr after IF had been introduced...
  18. ncbi request reprint Large differences in incidences of overt hyper- and hypothyroidism associated with a small difference in iodine intake: a prospective comparative register-based population survey
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 87:4462-9. 2002
    ..The optimal level of iodine intake to prevent thyroid disease may be a relatively narrow range around the recommended daily iodine intake of 150 micro g...
  19. ncbi request reprint Relations between various measures of iodine intake and thyroid volume, thyroid nodularity, and serum thyroglobulin
    Lone B Rasmussen
    Institute of Food Research and Nutrition, The Danish Veterinary and Food Administration, Søborg, Denmark
    Am J Clin Nutr 76:1069-76. 2002
    ..Iodine intake can be measured in various ways, and each method may have advantages and disadvantages...
  20. ncbi request reprint The Danish investigation on iodine intake and thyroid disease, DanThyr: status and perspectives
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 155:219-28. 2006
    ..p.m. iodine) was initiated in 2000/2001. The Danish investigation on iodine intake and thyroid disease (DanThyr) is the monitoring of the iodine fortification program...
  21. ncbi request reprint A population study of the association between thyroid autoantibodies in serum and abnormalities in thyroid function and structure
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Denmark
    Clin Endocrinol (Oxf) 62:713-20. 2005
    ..The aims of this study were to evaluate the association between thyroid autoantibodies in serum and abnormalities in thyroid function and structure, and to study the thyroid volume in subjects with subclinical autoimmune hypothyroidism...
  22. ncbi request reprint Epidemiology of subtypes of hypothyroidism in Denmark
    Allan Carlé
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 154:21-8. 2006
    ..We therefore studied incidences of subtypes of primary, overt hypothyroidism in a Danish population cohort and compared incidences in two subcohorts with different levels of iodine intake...
  23. ncbi request reprint Lack of association between thyroid autoantibodies and parity in a population study argues against microchimerism as a trigger of thyroid autoimmunity
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 154:39-45. 2006
    ..It has also been suggested that foetal microchimerism involving transfer of foetal cells into maternal tissue during pregnancy may play an important role...
  24. ncbi request reprint Thyroid peroxidase and thyroglobulin autoantibodies in a large survey of populations with mild and moderate iodine deficiency
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Denmark
    Clin Endocrinol (Oxf) 58:36-42. 2003
    ..In the present study we evaluated if TPO-Ab and Tg-Ab tend to develop in parallel or whether one or the other may be more prevalent in subsets of the population...
  25. ncbi request reprint Increase in incidence of hyperthyroidism predominantly occurs in young people after iodine fortification of salt in Denmark
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 91:3830-4. 2006
    ..We prospectively registered all new cases of overt hyperthyroidism in two areas of Denmark before and for the first 6 yr after iodine fortification...
  26. ncbi request reprint Age modifies the pituitary TSH response to thyroid failure
    Allan Carlé
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Denmark
    Thyroid 17:139-44. 2007
    ..To investigate the association between serum TSH, total T4 and various patient characteristics when hypothyroidism is diagnosed in a population, and to study how age, sex and serum T4 levels influenced pituitary TSH response...
  27. ncbi request reprint Thiocyanate in food and iodine in milk: from domestic animal feeding to improved understanding of cretinism
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aalborg, Denmark
    Thyroid 12:897-902. 2002
    ..It can be speculated that a low-iodine content of mother's milk because of inhibition of NIS in the mammary gland may be one factor of importance for development of myxedematous cretinism...
  28. ncbi request reprint Dietary iodine intake and urinary iodine excretion in a Danish population: effect of geography, supplements and food choice
    Lone B Rasmussen
    Institute of Food Research and Nutrition, Danish Veterinary and Food Administration, Søborg, Denmark
    Br J Nutr 87:61-9. 2002
    ..Even individuals who followed the advice regarding intake of 200-300 g fish/week and 0.5 litres milk/d had an intake below the recommended level if living in Aalborg...
  29. ncbi request reprint Surveyance of disease frequency in a population by linkage to diagnostic laboratory databases. A system for monitoring the incidences of hyper- and hypothyroidism as part of the Danish iodine supplementation program
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Reberbansgade, DK 9000 Aalborg, Denmark
    Comput Methods Programs Biomed 67:209-16. 2002
    ..In Denmark an increase in iodine intake through salt iodization has been introduced in 1998. In parallel a program for surveyance of thyroid diseases in the population was developed as recommended by UNICEF and WHO...
  30. doi request reprint Smoking is negatively associated with the presence of thyroglobulin autoantibody and to a lesser degree with thyroid peroxidase autoantibody in serum: a population study
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 158:367-73. 2008
    ..The knowledge of a possible association between lifestyle factors and circulating thyroid antibodies is limited...