Daniel G Smith

Summary

Affiliation: H. Lundbeck A/S
Country: Denmark

Publications

  1. ncbi Melanin-concentrating hormone-1 receptor modulates neuroendocrine, behavioral, and corticolimbic neurochemical stress responses in mice
    Daniel G Smith
    Neuroscience Discovery Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Neuropsychopharmacology 31:1135-45. 2006
  2. ncbi Behavioral and biochemical responses to d-amphetamine in MCH1 receptor knockout mice
    Daniel G Smith
    Eli Lilly and Company, Neuroscience Discovery Research, Indianapolis, Indiana 46285, USA
    Synapse 62:128-36. 2008
  3. doi The effects of stressful stimuli and hypothalamic-pituitary-adrenal axis activation are reversed by the melanin-concentrating hormone 1 receptor antagonist SNAP 94847 in rodents
    Daniel G Smith
    Department of Neuroscience, Lundbeck Research USA, 215 College Road, Paramus, NJ 07652, United States
    Behav Brain Res 197:284-91. 2009
  4. ncbi Exposure to predator odor stress increases efflux of frontal cortex acetylcholine and monoamines in mice: comparisons with immobilization stress and reversal by chlordiazepoxide
    Daniel G Smith
    Neuroscience Discovery Research, Eli Lilly and Company, Indianapolis, IN 46278, USA
    Brain Res 1114:24-30. 2006
  5. ncbi Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice
    Daniel G Smith
    Neuroscience Discovery Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA
    J Neurosci 25:914-22. 2005

Detail Information

Publications5

  1. ncbi Melanin-concentrating hormone-1 receptor modulates neuroendocrine, behavioral, and corticolimbic neurochemical stress responses in mice
    Daniel G Smith
    Neuroscience Discovery Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Neuropsychopharmacology 31:1135-45. 2006
    ..Distinct behavioral, physiological, and neurochemical stress, and anxiety-related responses were selectively modulated by the MCHR1, and these actions may involve corticolimbic regulation of stress responsivity and anxiety...
  2. ncbi Behavioral and biochemical responses to d-amphetamine in MCH1 receptor knockout mice
    Daniel G Smith
    Eli Lilly and Company, Neuroscience Discovery Research, Indianapolis, Indiana 46285, USA
    Synapse 62:128-36. 2008
    ....
  3. doi The effects of stressful stimuli and hypothalamic-pituitary-adrenal axis activation are reversed by the melanin-concentrating hormone 1 receptor antagonist SNAP 94847 in rodents
    Daniel G Smith
    Department of Neuroscience, Lundbeck Research USA, 215 College Road, Paramus, NJ 07652, United States
    Behav Brain Res 197:284-91. 2009
    ..The regulation of ACTH release and reversal of the effects of chronic and acute stress by SNAP 94847 are suggestive of a role for MCH(1) receptor blockade in the treatment of disorders characterized by high allostatic load...
  4. ncbi Exposure to predator odor stress increases efflux of frontal cortex acetylcholine and monoamines in mice: comparisons with immobilization stress and reversal by chlordiazepoxide
    Daniel G Smith
    Neuroscience Discovery Research, Eli Lilly and Company, Indianapolis, IN 46278, USA
    Brain Res 1114:24-30. 2006
    ..Overall, we demonstrate a novel method to measure the effects of distinctly different stress modalities on FC neurotransmission and suggest that FC responsivity to stressors may be an important marker for evaluating anxiolytic drugs...
  5. ncbi Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice
    Daniel G Smith
    Neuroscience Discovery Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA
    J Neurosci 25:914-22. 2005
    ..MCH1r may be an important therapeutic target for neuropsychiatric disorders involving dysregulation of limbic monoamine systems...