Albert Gjedde

Summary

Country: Denmark

Publications

  1. doi request reprint Data-driven intensity normalization of PET group comparison studies is superior to global mean normalization
    Per Borghammer
    PET Center, Aarhus University Hospitals, Denmark
    Neuroimage 46:981-8. 2009
  2. doi request reprint Cortical hypometabolism and hypoperfusion in Parkinson's disease is extensive: probably even at early disease stages
    Per Borghammer
    Department of Nuclear Medicine, Aarhus University Hospitals, Aarhus Sygehus, Aarhus, Denmark
    Brain Struct Funct 214:303-17. 2010
  3. doi request reprint Relief of fecal incontinence by sacral nerve stimulation linked to focal brain activation
    Lilli Lundby
    Department of Surgery P, Aarhus University Hospital and Aarhus University, Aarhus, Denmark
    Dis Colon Rectum 54:318-23. 2011
  4. pmc Deep brain stimulation reveals emotional impact processing in ventromedial prefrontal cortex
    Albert Gjedde
    Pathophysiology and Experimental Tomography Center, Aarhus University Hospitals, Aarhus, Denmark
    PLoS ONE 4:e8120. 2009
  5. pmc Inverted-U-shaped correlation between dopamine receptor availability in striatum and sensation seeking
    Albert Gjedde
    Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark
    Proc Natl Acad Sci U S A 107:3870-5. 2010
  6. doi request reprint Diffusive insights: on the disagreement of Christian Bohr and August Krogh at the Centennial of the Seven Little Devils
    Albert Gjedde
    Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark
    Adv Physiol Educ 34:174-85. 2010
  7. doi request reprint No oxygen delivery limitation in hepatic encephalopathy
    Albert Gjedde
    Pathophysiology and Experimental Tomography Center, Aarhus Hospital, Aarhus University Hospitals, Aarhus, Denmark
    Metab Brain Dis 25:57-63. 2010
  8. doi request reprint Variable ATP yields and uncoupling of oxygen consumption in human brain
    Albert Gjedde
    Pathophysiology and Experimental Tomography Center, University of Aarhus, Aarhus, Denmark
    Adv Exp Med Biol 701:243-8. 2011
  9. ncbi request reprint The Danish PET/depression project: performance on Stroop's test linked to white matter lesions in the brain
    Poul Videbech
    Institute for Basic Psychiatric Research, Department of Biological Psychiatry, Psychiatric Hospital, Aarhus University Hospitals, DK 8240 Risskov, Denmark
    Psychiatry Res 130:117-30. 2004
  10. ncbi request reprint Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder
    Pedro Rosa-Neto
    Center for Functionally Integrative Neuroscience, Aarhus University and PET Center, Aarhus University Hospitals, 44 Nørrebrogade, Building 10, Aarhus C 8000, Denmark
    Neuroimage 25:868-76. 2005

Detail Information

Publications59

  1. doi request reprint Data-driven intensity normalization of PET group comparison studies is superior to global mean normalization
    Per Borghammer
    PET Center, Aarhus University Hospitals, Denmark
    Neuroimage 46:981-8. 2009
    ..Importantly, such GM differences often elude detection due to the large intrinsic variance in absolute values of cerebral blood flow or glucose consumption. Alternative methods of normalization are needed for this type of data...
  2. doi request reprint Cortical hypometabolism and hypoperfusion in Parkinson's disease is extensive: probably even at early disease stages
    Per Borghammer
    Department of Nuclear Medicine, Aarhus University Hospitals, Aarhus Sygehus, Aarhus, Denmark
    Brain Struct Funct 214:303-17. 2010
    ..Based on the results, we conclude that PD most likely has widespread cortical hypometabolism, even at early disease stages. In contrast, extensive subcortical hypermetabolism is probably not a feature of PD...
  3. doi request reprint Relief of fecal incontinence by sacral nerve stimulation linked to focal brain activation
    Lilli Lundby
    Department of Surgery P, Aarhus University Hospital and Aarhus University, Aarhus, Denmark
    Dis Colon Rectum 54:318-23. 2011
    ..This study aimed to test the hypothesis that sacral nerve stimulation affects afferent vagal projections to the central nervous system associated with frontal cortex activation in patients with fecal incontinence...
  4. pmc Deep brain stimulation reveals emotional impact processing in ventromedial prefrontal cortex
    Albert Gjedde
    Pathophysiology and Experimental Tomography Center, Aarhus University Hospitals, Aarhus, Denmark
    PLoS ONE 4:e8120. 2009
    ....
  5. pmc Inverted-U-shaped correlation between dopamine receptor availability in striatum and sensation seeking
    Albert Gjedde
    Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark
    Proc Natl Acad Sci U S A 107:3870-5. 2010
    ....
  6. doi request reprint Diffusive insights: on the disagreement of Christian Bohr and August Krogh at the Centennial of the Seven Little Devils
    Albert Gjedde
    Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark
    Adv Physiol Educ 34:174-85. 2010
    ..August Krogh, of course, was right in the wider sense that the transport mechanism itself is always entirely passive...
  7. doi request reprint No oxygen delivery limitation in hepatic encephalopathy
    Albert Gjedde
    Pathophysiology and Experimental Tomography Center, Aarhus Hospital, Aarhus University Hospitals, Aarhus, Denmark
    Metab Brain Dis 25:57-63. 2010
    ..We ascribe the inability to use the delivered oxygen of patients with HE to a specific inhibition associated with oxidative metabolism in mitochondria...
  8. doi request reprint Variable ATP yields and uncoupling of oxygen consumption in human brain
    Albert Gjedde
    Pathophysiology and Experimental Tomography Center, University of Aarhus, Aarhus, Denmark
    Adv Exp Med Biol 701:243-8. 2011
    ..Thus the hypothetical threshold of oxygen metabolism coupled to ATP turnover in all subjects is no more than 70% of the average oxygen consumption of that population...
  9. ncbi request reprint The Danish PET/depression project: performance on Stroop's test linked to white matter lesions in the brain
    Poul Videbech
    Institute for Basic Psychiatric Research, Department of Biological Psychiatry, Psychiatric Hospital, Aarhus University Hospitals, DK 8240 Risskov, Denmark
    Psychiatry Res 130:117-30. 2004
    ..We thus partly explain the poorer performance by increased frequency of WML in frontostriatal pathways in the depressed patients, impairing neurotransmission...
  10. ncbi request reprint Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder
    Pedro Rosa-Neto
    Center for Functionally Integrative Neuroscience, Aarhus University and PET Center, Aarhus University Hospitals, 44 Nørrebrogade, Building 10, Aarhus C 8000, Denmark
    Neuroimage 25:868-76. 2005
    ..04). In conclusion, the results link inattention and impulsivity with sensitivity of brain DA receptor availability to an MP challenge, corroborating the hypothesis that MP serves to potentiate decreased DA neurotransmission in ADHD...
  11. ncbi request reprint MDMA-evoked changes in [11C]raclopride and [11C]NMSP binding in living pig brain
    Pedro Rosa-Neto
    Center for Functionally Integrative Neuroscience, Aarhus University and PET Center, Aarhus University Hospitals, Aarhus C, 8000, Denmark
    Synapse 53:222-33. 2004
    ..Distinct properties of MDMA such as simultaneous release of dopamine and serotonin in brain may account for the present finding of progressive decline in the availability of [11C]NMSP binding sites in striatum...
  12. doi request reprint Cognitive and emotional modulation of brain default operation
    Karen Johanne Pallesen
    Center of Functionally Integrative Neuroscience, Aarhus University Hospitals, Denmark
    J Cogn Neurosci 21:1065-80. 2009
    ..The results also indicate that task-related decreases may be further modulated by the emotional stimulus connotation...
  13. pmc Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia
    Michael Gejl
    Department of Biomedicine, Aarhus University, Aarhus, Denmark
    J Cereb Blood Flow Metab 32:2146-52. 2012
    ....
  14. pmc Oxygen consumption and blood flow coupling in human motor cortex during intense finger tapping: implication for a role of lactate
    Manouchehr S Vafaee
    Department of Neuroscience and Pharmacology, Faculty of Health Sciences, University of Copenhagen, Copenhagen N, Denmark
    J Cereb Blood Flow Metab 32:1859-68. 2012
    ..The implied generation of lactate in the tissue suggested an important hypothetical role of the metabolite as regulator of CBF during activation...
  15. ncbi request reprint Parametric mapping of 5HT1A receptor sites in the human brain with the Hypotime method: theory and normal values
    Mette Møller
    Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark
    J Nucl Med 50:1229-36. 2009
    ..Here, we proposed a method of calculation (Hypotime) that specifically uses the washout rather than the accumulation of (11)C-WAY to determine binding potentials (BP(ND)), without the use of regression analysis...
  16. pmc Brain energy metabolism and blood flow differences in healthy aging
    Joel Aanerud
    Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark
    J Cereb Blood Flow Metab 32:1177-87. 2012
    ..The results establish a possible mechanism of progression from healthy to unhealthy brain aging, as the regions most affected by age are the areas that are most vulnerable to neurodegeneration...
  17. doi request reprint Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning
    Adjmal Nahimi
    Center of Functionally Integrative Neuroscience, Aarhus University Hospitals, Aarhus University, Denmark
    J Neurochem 120:806-17. 2012
    ....
  18. doi request reprint Normalization in PET group comparison studies--the importance of a valid reference region
    Per Borghammer
    PET Center, Aarhus University Hospitals, Denmark
    Neuroimage 40:529-40. 2008
    ....
  19. ncbi request reprint Low cerebral oxygen consumption and blood flow in patients with cirrhosis and an acute episode of hepatic encephalopathy
    Peter Iversen
    PET Centre, Aarhus University Hospital, Aarhus, Denmark
    Gastroenterology 136:863-71. 2009
    ..It is unclear whether patients with hepatic encephalopathy (HE) have disturbed brain oxygen metabolism and blood flow...
  20. ncbi request reprint Cerebral metabolic response to low blood flow: possible role of cytochrome oxidase inhibition
    Albert Gjedde
    Pathophysiology and Experimental Tomography Center, Aarhus University Hospital in Aarhus, Aarhus, Denmark
    J Cereb Blood Flow Metab 25:1183-96. 2005
    ..The adjustment of cytochrome c oxidase affinity to the declining oxygen delivery could be ascribed to a hypothetical factor with several properties in common with nitric oxide...
  21. doi request reprint Dopamine release in ventral striatum during Iowa Gambling Task performance is associated with increased excitement levels in pathological gambling
    Jakob Linnet
    Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark
    Addiction 106:383-90. 2011
    ..Here, we tested the hypothesis that dopamine release would be associated with increased excitement levels in Pathological Gamblers compared with Healthy Controls...
  22. doi request reprint Pathological gambling: relation of skin conductance response to dopaminergic neurotransmission and sensation-seeking
    Ericka Peterson
    Department of Neuroscience and Pharmacology, School of Medicine and Health Sciences, University of Copenhagen, 3 Blegdamsvej, Copenhagen, 2200, Denmark
    Eur Neuropsychopharmacol 20:766-75. 2010
    ..05 and P = 0.02, respectively) and together (P < 0.0005). We conclude that SCR is less conditioned by dopaminergic activity in highly sensation-seeking subjects, regardless of PG status...
  23. doi request reprint Attention, emotion, and deactivation of default activity in inferior medial prefrontal cortex
    Jacob Geday
    Pathophysiology and Experimental Tomography Center, Aarhus University Hospitals, Norrebrogade 44, Bygn 10, 8000 Aarhus C, Denmark
    Brain Cogn 69:344-52. 2009
    ..The absent emotional interference with the deactivation of the default state suggests that the inferior prefrontal cortex continued to serve the attention rather than submit to the distraction...
  24. ncbi request reprint Capillary-oxygenation-level-dependent near-infrared spectrometry in frontal lobe of humans
    Peter Rasmussen
    Copenhagen Muscle Research Centre, Department of Anaesthesia, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark
    J Cereb Blood Flow Metab 27:1082-93. 2007
    ....
  25. ncbi request reprint Stimulation of subthalamic nucleus inhibits emotional activation of fusiform gyrus
    Jacob Geday
    Pathophysiology and Experimental Tomography Center, Aarhus University Hospital, Noerrebrogade 44, 8000 Aarhus C, Denmark
    Neuroimage 33:706-14. 2006
    ..The findings suggest that the stimulation of the subthalamic nucleus interferes with the integration of specific neocortical networks involved in the recognition of facial expressions...
  26. ncbi request reprint Subcortical elevation of metabolism in Parkinson's disease--a critical reappraisal in the context of global mean normalization
    Per Borghammer
    PET Centre, Aarhus University Hospitals, Aarhus, Denmark
    Neuroimage 47:1514-21. 2009
    ..In the absence of quantitative evidence for the PDRP, our alternative interpretation of normalization bias seems the more parsimonious explanation for the reports of relative hypermetabolism in PD...
  27. ncbi request reprint As time goes by: temporal constraints on emotional activation of inferior medial prefrontal cortex
    Jacob Geday
    PET Center, Aarhus University Hospitals, Aarhus, Denmark
    Cereb Cortex 17:2753-9. 2007
    ..The results emphasize the importance of implicit cognitive processing during emotional activation, however, unintended...
  28. ncbi request reprint STN-stimulation in Parkinson's disease restores striatal inhibition of thalamocortical projection
    Jacob Geday
    PET Center, Aarhus University Hospitals, Aarhus, Denmark
    Hum Brain Mapp 30:112-21. 2009
    ....
  29. doi request reprint Glucose metabolism in small subcortical structures in Parkinson's disease
    Per Borghammer
    PET Centre, Aarhus University Hospitals, Denmark
    Acta Neurol Scand 125:303-10. 2012
    ..However, the high-resolution research tomograph (HRRT) PET system has a resolution of 2 mm, sufficient for the investigation of important structures such as the pallidum and thalamic subnuclei...
  30. ncbi request reprint Spatially dissociated flow-metabolism coupling in brain activation
    Manouchehr S Vafaee
    Center of Functionally Integrative Neuroscience, University of Aarhus, and PET Center, Aarhus University Hospitals, Aarhus, Denmark
    Neuroimage 21:507-15. 2004
    ..By this mechanism, CBF rose in the putamen before the measurements of CBF and CMRO(2) while CMRO(2) rose when actual motion commenced...
  31. ncbi request reprint ADHD: increased dopamine receptor availability linked to attention deficit and low neonatal cerebral blood flow
    Hans C Lou
    Centre of Functionally Integrative Neuroscience and PET Centre, Aarhus University Hospital, Aarhus, Denmark
    Dev Med Child Neurol 46:179-83. 2004
    ..High dopamine receptor availability was predicted by low neonatal CBF, supporting the hypothesis of cerebral ischaemia as a contributing factor in infants susceptible to ADHD...
  32. ncbi request reprint Separate neural pathways for contour and biological-motion cues in motion-defined animal shapes
    Maurice Ptito
    The PET Center, Aarhus University, 8000C, Aarhus, Denmark
    Neuroimage 19:246-52. 2003
    ..They further support psychophysical results showing that contour and BM cues for motion-defined animal shapes are processed by independent channels...
  33. pmc Increased turnover of dopamine in caudate nucleus of detoxified alcoholic patients
    Yoshitaka Kumakura
    Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark Center for Functionally Integrative Neuroscience, Aarhus University, Aarhus C, Denmark Department of Nuclear Medicine, Tokyo University, Tokyo, Japan
    PLoS ONE 8:e73903. 2013
    ....
  34. pmc Influence of GLP-1 on myocardial glucose metabolism in healthy men during normo- or hypoglycemia
    Michael Gejl
    Department of Biomedicine, Aarhus University, Aarhus, Denmark
    PLoS ONE 9:e83758. 2014
    ..We assessed the effects of GLP-1 on MGU in healthy subjects during normo- and hypoglycemia...
  35. ncbi request reprint Glucagon-like peptide-1 inhibits blood-brain glucose transfer in humans
    Susanne Lerche
    Institute of Pharmacology, University of Aarhus, The Bartholin Building, University Park 1240, 8000 Aarhus C, Denmark
    Diabetes 57:325-31. 2008
    ..Recent research in rodents suggests a protective effect of GLP-1 on brain tissue. The mechanism is unknown. We therefore tested whether these neuroprotective effects could relate to changes of glucose transport and consumption...
  36. ncbi request reprint Neuroprotection in hypothermia linked to redistribution of oxygen in brain
    Masaharu Sakoh
    Center of Functionally Integrative Neuroscience, University of Aarhus, Aarhus Hospitals, Aarhus, Denmark
    Am J Physiol Heart Circ Physiol 285:H17-25. 2003
    ..The results are consistent with the claim that cooling of the brain to 32 degrees C couples both energy metabolism and blood flow to a lower rate of work of the entire tissue...
  37. ncbi request reprint Neural mechanisms of voluntary and involuntary recall: a PET study
    Nicoline Marie Hall
    Center of Functionally Integrative Neuroscience, University of Aarhus, Denmark
    Behav Brain Res 186:261-72. 2008
    ..The relatively higher activity in precuneus during voluntary compared to involuntary recall suggests that activity in this region co-varies not only with retrieval success but also with retrieval intentionality...
  38. doi request reprint Monoaminergic modulation of emotional impact in the inferomedial prefrontal cortex
    Jacob Geday
    PET Center, Aarhus University, Aarhus, Denmark
    Synapse 63:160-6. 2009
    ..We propose a specific pharmacodynamic mechanism that explains the correlation between the emotional impact and the effect of a serotonin-noradrenaline reuptake inhibitor on cerebral blood flow...
  39. ncbi request reprint The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes
    Maja L Johansen
    Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, 2 Universitetsparken, 2100 Copenhagen, Denmark
    Neurochem Int 50:1042-51. 2007
    ..In conclusion, i) neuronal and astrocytic TCA cycle metabolism was not inhibited by ammonium and ii) isoleucine may provide the carbon skeleton for synthesis of glutamate/glutamine in the detoxification of ammonium...
  40. ncbi request reprint Cross-modal plasticity revealed by electrotactile stimulation of the tongue in the congenitally blind
    Maurice Ptito
    PET Centre and CFIN, Aarhus University Hospitals, Aarhus, Denmark
    Brain 128:606-14. 2005
    ..Our data further show that the tongue can act as a portal to convey somatosensory information to visual cortex...
  41. doi request reprint Coupling between the blood lactate-to-pyruvate ratio and MCA Vmean at the onset of exercise in humans
    Peter Rasmussen
    1Department of Anesthesia, Copenhagen Muscle Research Center, Rigshospitalet, Copenhagen, Denmark
    J Appl Physiol (1985) 107:1799-805. 2009
    ..These findings support brain tissue redox state and oxygenation as potential modulators of an increase in cerebral blood flow at the onset of exercise...
  42. doi request reprint Reestablishing speech understanding through musical ear training after cochlear implantation: a study of the potential cortical plasticity in the brain
    Bjørn Petersen
    Center of Functionally Integrative Neuroscience, Aarhus University Hospital, Aarhus, Denmark
    Ann N Y Acad Sci 1169:437-40. 2009
    ..The goal is to find and work out musical methods to improve CI users' auditory capabilities and, in a longer perspective, provide an efficient strategy for improving speech understanding for both adults and children with CIs...
  43. ncbi request reprint MDMA-evoked changes in cerebral blood flow in living porcine brain: correlation with hyperthermia
    Pedro Rosa-Neto
    Center for Functionally Integrative Neuroscience, Aarhus University and PET Center, Aarhus University Hospitals, Aarhus C, 8000, Denmark
    Synapse 53:214-21. 2004
    ....
  44. doi request reprint Principal cell spiking, postsynaptic excitation, and oxygen consumption in the rat cerebellar cortex
    Kirsten Thomsen
    Institute of Neuroscience and Pharmacology, University of Copenhagen, and Department of Clinical Neurophysiology, Glostrup Hospital, Panum Institute 12 5, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    J Neurophysiol 102:1503-12. 2009
    ..Our findings imply that CMRO2 responses cannot a priori be assigned to specific neuronal activities...
  45. doi request reprint Striatal dopamine release codes uncertainty in pathological gambling
    Jakob Linnet
    Research Clinic on Gambling Disorders, Aarhus University Hospital, Nørrebrogade 44, Building 30, DK 8000 Aarhus C, Denmark
    Psychiatry Res 204:55-60. 2012
    ..The findings have implications for understanding dopamine dysfunctions in pathological gambling and addictive behaviors...
  46. doi request reprint Huntington's disease-like and ataxia syndromes: identification of a family with a de novo SCA17/TBP mutation
    Sara Bech
    Department of Cellular and Molecular Medicine, Section of Neurogenetics, The Panum Institute, University of Copenhagen, Denmark
    Parkinsonism Relat Disord 16:12-5. 2010
    ..We conclude that, however rare, SCA17 must be considered as a cause of Huntington's disease-like phenotypes and ataxia syndromes, also in isolated cases...
  47. ncbi request reprint PET studies of net blood-brain clearance of FDOPA to human brain: age-dependent decline of [18F]fluorodopamine storage capacity
    Yoshitaka Kumakura
    PET Centre, Aarhus University Hospitals, Aarhus, Denmark
    J Cereb Blood Flow Metab 25:807-19. 2005
    ..The present results furthermore constitute the first demonstration of an abnormality in the cerebral utilization of FDOPA in caudate and putamen as a function of normal aging, which we attribute to loss of vesicular storage capacity...
  48. ncbi request reprint Emotional valence modulates activity in the posterior fusiform gyrus and inferior medial prefrontal cortex in social perception
    Jacob Geday
    PET Center, Aarhus University and Aarhus University Hospital, Aarhus, Denmark
    Neuroimage 18:675-84. 2003
    ..We believe that this is a crucial part of a network used in normal empathic reactions and social interactions...
  49. ncbi request reprint The Danish PET/depression project: poor verbal fluency performance despite normal prefrontal activation in patients with major depression
    Poul Videbech
    Department of Biological Psychiatry, Psychiatric Hospital, Aarhus University Hospitals, DK 8240 Risskov, Denmark
    Psychiatry Res 123:49-63. 2003
    ....
  50. ncbi request reprint Parametric and regional maps of free serotonin 5HT1A receptor sites in human brain as function of age in healthy humans
    Mette Møller
    Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark
    Neuropsychopharmacology 32:1707-14. 2007
    ..The results demonstrate that the number of available 5HT(1A)-binding sites declines with age...
  51. ncbi request reprint Cortical responses to promontorial stimulation in postlingual deafness
    Malene Vejby Mortensen
    PET Center, Aarhus University Hospitals, Denmark
    Hear Res 209:32-41. 2005
    ..We conclude that the ability to involve the right posterior temporal region is important to duration discrimination. This ability can be evaluated pre-operatively...
  52. ncbi request reprint Minipig negative slow wave demonstrates target/nontarget differences in P300 paradigm
    Sidse Marie Arnfred
    Department of Psychiatry, H S Bispebjerg Hospital, University Hospital of Copenhagen, Copenhagen, Denmark
    Neuroimage 20:587-90. 2003
    ..After training, target NSW amplitude was increased 50% compared to nontarget. A P350 was recognized, but the finding of a lack of target/nontarget difference is not conclusive...
  53. doi request reprint Increased sensitivity to supra-threshold painful stimuli in patients with multiple functional somatic symptoms (MFS)
    Ruta Kuzminskyte
    Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospitals, Aarhus, Denmark
    Brain Res Bull 82:135-40. 2010
    ..Minor increases in stimulus intensity of supra-threshold painful stimuli may lead to disproportionate increases in pain intensity in MFS patients, suggesting a defunct endogenous pain modulatory system...
  54. ncbi request reprint To musicians, the message is in the meter pre-attentive neuronal responses to incongruent rhythm are left-lateralized in musicians
    Peter Vuust
    Centre for Functionally Integrative Neuroscience, University of Aarhus, Aarhus, Denmark
    Neuroimage 24:560-4. 2005
    ..The left-lateralization of the pre-attentive responses suggests functional adaptation of the brain to a task of communication, which is much like that of language...
  55. ncbi request reprint Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated Göttingen miniature pigs
    Paul Cumming
    PET Center, Arhus University Hospitals, Nørrebrogade 44, Aarhus, Denmark
    Nucl Med Biol 30:547-53. 2003
    ..Results of this preliminary study indicate that this tracer meets many requirements for assaying dopamine agonist binding sites by PET...
  56. ncbi request reprint Cerebral blood flow change in arterial hypoxemia is consistent with negligible oxygen tension in brain mitochondria
    Albert Gjedde
    Pathophysiology and Experimental Tomography Center, Aarhus University Hospitals, Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus, 8000 Denmark
    Neuroimage 17:1876-81. 2002
    ....
  57. ncbi request reprint [11C]Mirtazapine for PET neuroimaging: radiosynthesis and initial evaluation in the living porcine brain
    Katalin Marthi
    PET Center, Aarhus University Hospital, Nørrebrogade 44, DK 8000 C, Aarhus, Denmark
    Eur Neuropsychopharmacol 12:427-32. 2002
    ....
  58. ncbi request reprint Putative tests of frontal lobe function: a PET-study of brain activation during Stroop's Test and verbal fluency
    Barbara Ravnkilde
    Institute for Basic Psychiatric Research, Department of Biological Psychiatry, Psychiatric Hospital, Aarhus University Hospitals, Denmark
    J Clin Exp Neuropsychol 24:534-47. 2002
    ..These results bring this latter test closer to being a specific test of prefrontal function...