Ole Raaschou-Nielsen

Summary

Affiliation: Danish Cancer Society
Country: Denmark

Publications

  1. pmc Non-occupational exposure to paint fumes during pregnancy and risk of congenital anomalies: a cohort study
    Dorrit Hjortebjerg
    Danish Cancer Society Research Centre, Copenhagen, Denmark
    Environ Health 11:54. 2012
  2. doi Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE)
    Ole Raaschou-Nielsen
    Danish Cancer Society Research Center, Copenhagen, Denmark
    Lancet Oncol 14:813-22. 2013
  3. doi Long-term exposure to traffic-related air pollution and diabetes-associated mortality: a cohort study
    O Raaschou-Nielsen
    Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen Ø, Denmark
    Diabetologia 56:36-46. 2013
  4. pmc Traffic air pollution and mortality from cardiovascular disease and all causes: a Danish cohort study
    Ole Raaschou-Nielsen
    Danish Cancer Society Research Center, Copenhagen, Denmark
    Environ Health 11:60. 2012
  5. doi Residential radon and lung cancer incidence in a Danish cohort
    Elvira V Bräuner
    Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen, Denmark
    Environ Res 118:130-6. 2012
  6. pmc Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals
    Elvira V Bräuner
    Institute of Public Health, Department of Environmental Health, Health Science Faculty, University of Copenhagen, Denmark
    Part Fibre Toxicol 5:13. 2008
  7. pmc Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries: a prospective study
    Paolo Vineis
    Imperial College London, London UK
    Environ Health 6:7. 2007
  8. pmc Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP
    Bjørn A Nexø
    Institute of Human Genetics, University of Aarhus, DK 8000 Aarhus C, Denmark
    BMC Med Genet 9:56. 2008
  9. ncbi Bulky DNA adducts as risk indicator of lung cancer in a Danish case-cohort study
    Helle Bak
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 118:1618-22. 2006
  10. pmc Air pollution from traffic and cancer incidence: a Danish cohort study
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Environ Health 10:67. 2011

Detail Information

Publications103 found, 100 shown here

  1. pmc Non-occupational exposure to paint fumes during pregnancy and risk of congenital anomalies: a cohort study
    Dorrit Hjortebjerg
    Danish Cancer Society Research Centre, Copenhagen, Denmark
    Environ Health 11:54. 2012
    ..Organic solvents are also used in the home environments in paint products, but no study has investigated the effect of such exposure in a general population...
  2. doi Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE)
    Ole Raaschou-Nielsen
    Danish Cancer Society Research Center, Copenhagen, Denmark
    Lancet Oncol 14:813-22. 2013
    ..Ambient air pollution is suspected to cause lung cancer. We aimed to assess the association between long-term exposure to ambient air pollution and lung cancer incidence in European populations...
  3. doi Long-term exposure to traffic-related air pollution and diabetes-associated mortality: a cohort study
    O Raaschou-Nielsen
    Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen Ø, Denmark
    Diabetologia 56:36-46. 2013
    ..The aim of this study was to investigate whether air pollution from traffic at a residence is associated with mortality related to type 1 or type 2 diabetes...
  4. pmc Traffic air pollution and mortality from cardiovascular disease and all causes: a Danish cohort study
    Ole Raaschou-Nielsen
    Danish Cancer Society Research Center, Copenhagen, Denmark
    Environ Health 11:60. 2012
    ..Traffic air pollution has been linked to cardiovascular mortality, which might be due to co-exposure to road traffic noise. Further, personal and lifestyle characteristics might modify any association...
  5. doi Residential radon and lung cancer incidence in a Danish cohort
    Elvira V Bräuner
    Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen, Denmark
    Environ Res 118:130-6. 2012
    ..Our results provide valuable information at the low-level radon dose range...
  6. pmc Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals
    Elvira V Bräuner
    Institute of Public Health, Department of Environmental Health, Health Science Faculty, University of Copenhagen, Denmark
    Part Fibre Toxicol 5:13. 2008
    ..abstract:..
  7. pmc Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries: a prospective study
    Paolo Vineis
    Imperial College London, London UK
    Environ Health 6:7. 2007
    ..It is therefore useful to estimate the burden of disease associated with indoor and outdoor air pollution...
  8. pmc Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP
    Bjørn A Nexø
    Institute of Human Genetics, University of Aarhus, DK 8000 Aarhus C, Denmark
    BMC Med Genet 9:56. 2008
    ..The study groups included 434 postmenopausal breast cancer cases and an identical number of individually matched controls...
  9. ncbi Bulky DNA adducts as risk indicator of lung cancer in a Danish case-cohort study
    Helle Bak
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 118:1618-22. 2006
    ..Our results indicate that bulky DNA adducts may have a weak association with lung cancer risk...
  10. pmc Air pollution from traffic and cancer incidence: a Danish cohort study
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Environ Health 10:67. 2011
    ..Our aim was to investigate whether air pollution from traffic is associated with risk for other cancers than lung cancer...
  11. pmc Lung cancer incidence and long-term exposure to air pollution from traffic
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Environ Health Perspect 119:860-5. 2011
    ..Previous studies have shown associations between air pollution and risk for lung cancer...
  12. ncbi GPX1 Pro198Leu polymorphism, interactions with smoking and alcohol consumption, and risk for lung cancer
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark
    Cancer Lett 247:293-300. 2007
    ..03). We found stronger associations between several smoking variables and alcohol intake and lung cancer risk among GPX1(TT) carriers than among GPX1(CC) and GPX1(CT) carriers...
  13. doi Air pollution from traffic and risk for lung cancer in three Danish cohorts
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark
    Cancer Epidemiol Biomarkers Prev 19:1284-91. 2010
    ..The purpose was to investigate whether the concentration of nitrogen oxides (NOx) at the residence, used as an indicator of air pollution from traffic, is associated with risk for lung cancer...
  14. pmc Increasing incidence of childhood tumours of the central nervous system in Denmark, 1980-1996
    O Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK 2100 Copenhagen Ø, Denmark
    Br J Cancer 95:416-22. 2006
    ..These data suggest that the incidence rate of CNS tumours among Danish children has truly increased, although alternative explanations cannot be excluded...
  15. doi Indoor radon and childhood leukaemia
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark
    Radiat Prot Dosimetry 132:175-81. 2008
    ....
  16. doi Domestic radon and childhood cancer in Denmark
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Epidemiology 19:536-43. 2008
    ..We tested the hypothesis that domestic radon exposure increases the risk for childhood cancer...
  17. ncbi Polymorphisms in nucleotide excision repair genes, smoking and intake of fruit and vegetables in relation to lung cancer
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark
    Lung Cancer 59:171-9. 2008
    ..The incidence rate ratio for lung cancer was 0.60 (95% confidence interval: 0.43-0.84; p=0.003) per 50% increase in fruit intake. No convincing interactions were detected between the polymorphisms and smoking...
  18. ncbi Adipose organochlorine concentrations and risk of breast cancer among postmenopausal Danish women
    Ole Raaschou-Nielsen
    Danish Cancer Society, Institute of Cancer Epidemiology, Strandboulevarden 49, 2100 Copenhagen, Denmark
    Cancer Epidemiol Biomarkers Prev 14:67-74. 2005
    ..Our purpose was to examine associations between organochlorines and the development of breast cancer in a large prospective study using stored adipose tissue...
  19. ncbi [Effects on health of particulate air pollution in Denmark--a quantitative assessment]
    Ole Raaschou-Nielsen
    Institut for Epidemiologisk Kraeftforskning, Kraeftens Bekaempelse, Strandboulevarden 49, DK 2100 København Ø
    Ugeskr Laeger 164:3959-63. 2002
    ..Ambient air pollution is a risk factor for mortality and morbidity. The aim of this study was to quantify the health effects related to particulate matter (PM10) in Denmark...
  20. ncbi Cancer risk among workers at Danish companies using trichloroethylene: a cohort study
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Am J Epidemiol 158:1182-92. 2003
    ..Associations between trichloroethylene exposure and other cancers are less consistent...
  21. doi Predictors of indoor fine particulate matter in infants' bedrooms in Denmark
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark
    Environ Res 111:87-93. 2011
    ..Particulate matter (PM) in ambient air is responsible for adverse health effects in adults and children. Relatively little is known about the concentrations, sources and health effects of PM in indoor air...
  22. ncbi Urinary concentrations of trichloroacetic acid in Danish workers exposed to trichloroethylene, 1947-1985
    O Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK 2100 Copenhagen Ø, Denmark
    Am J Ind Med 39:320-7. 2001
    ..Since 1947, the National Labour Inspection Service in Denmark has relied upon urinary measurements of trichloroacetic acid (TCA) in surveys of the occupational exposure to trichloroethylene (TCE)...
  23. ncbi Air pollution from traffic at the residence of children with cancer
    O Raaschou-Nielsen
    Danish Cancer Society, Institute of Cancer Epidemiology, Strandboulevarden 49, DK 2100 Copenhagen 0, Denmark
    Am J Epidemiol 153:433-43. 2001
    ..06) and 51% (p for trend = 0.05) for a doubling of the concentration of benzene and nitrogen dioxide, respectively, during the pregnancy. The association was restricted to Hodgkin's disease...
  24. ncbi An air pollution model for use in epidemiological studies: evaluation with measured levels of nitrogen dioxide and benzene
    O Raaschou-Nielsen
    Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen O
    J Expo Anal Environ Epidemiol 10:4-14. 2000
    ..The results indicate that the OSPM used with the presented methods for generation of input data might be useful in assessing long-term exposure to air pollutants in epidemiological studies...
  25. ncbi Ambient air levels and the exposure of children to benzene, toluene, and xylenes in Denmark
    O Raaschou-Nielsen
    Division for Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Environ Res 75:149-59. 1997
    ....
  26. ncbi Socioeconomic status and risk of childhood leukaemia in Denmark
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Scand J Public Health 32:279-86. 2004
    ..The aim of this study was to assess the influence of socioeconomic status on the risk of childhood leukaemia...
  27. doi Lifestyle, environmental, and genetic predictors of bulky DNA adducts in a study population nested within a prospective Danish cohort
    Kirsten Thorup Eriksen
    Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, Denmark
    J Toxicol Environ Health A 73:583-95. 2010
    ..Overall, our study showed only few associations between dietary, environmental, and genetic factors and levels of bulky DNA adducts measured in peripheral leukocytes in a general Danish population...
  28. ncbi XPA A23G, XPC Lys939Gln, XPD Lys751Gln and XPD Asp312Asn polymorphisms, interactions with smoking, alcohol and dietary factors, and risk of colorectal cancer
    Rikke Dalgaard Hansen
    National Research Centre for the Working Environment, Lersø Parkallé 105, 2100 Copenhagen, Denmark
    Mutat Res 619:68-80. 2007
    ..Overall, the results of the present study indicate that the four polymorphisms are not of major importance in colorectal cancer carcinogenesis...
  29. pmc Long-term exposure to traffic-related air pollution associated with blood pressure and self-reported hypertension in a Danish cohort
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Environ Health Perspect 120:418-24. 2012
    ....
  30. doi Chronic obstructive pulmonary disease and long-term exposure to traffic-related air pollution: a cohort study
    Zorana J Andersen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Am J Respir Crit Care Med 183:455-61. 2011
    ..Short-term exposure to air pollution has been associated with exacerbation of chronic obstructive pulmonary disease (COPD), whereas the role of long-term exposures on the development of COPD is not yet fully understood...
  31. doi Stroke and long-term exposure to outdoor air pollution from nitrogen dioxide: a cohort study
    Zorana J Andersen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark
    Stroke 43:320-5. 2012
    ..We examined the association between long-term exposure to traffic-related air pollution and incident and fatal stroke in a prospective cohort study...
  32. pmc Exposure to road traffic and railway noise and associations with blood pressure and self-reported hypertension: a cohort study
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Environ Health 10:92. 2011
    ..Epidemiological studies suggest that long-term exposure to transport noise increases the risk for cardiovascular disorders. The effect of transport noise on blood pressure and hypertension is uncertain...
  33. ncbi Interactions between GSTM1, GSTT1 and GSTP1 polymorphisms and smoking and intake of fruit and vegetables in relation to lung cancer
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark
    Lung Cancer 55:137-44. 2007
    ..There were no significant interactions between the GST polymorphisms and smoking...
  34. doi Stratification for smoking in case-cohort studies of genetic polymorphisms and lung cancer
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark
    Lung Cancer 63:335-40. 2009
    ..Stratification for smoking seems to be advantageous in case-cohort studies of genetic polymorphisms and lung cancer...
  35. doi Association between 8-oxo-7,8-dihydroguanine excretion and risk of lung cancer in a prospective study
    Steffen Loft
    Department of Public Health, Section of Environmental Health, University of Copenhagen, Copenhagen, Denmark
    Free Radic Biol Med 52:167-72. 2012
    ..14 (0.98-1.34) among subjects homozygous for Cys326. The association between urinary 8-oxoGua excretion and lung cancer risk among former and never-smokers suggests that oxidative stress with damage to DNA is important in this group...
  36. doi Is there any interaction between domestic radon exposure and air pollution from traffic in relation to childhood leukemia risk?
    Elvira Vaclavik Bräuner
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark
    Cancer Causes Control 21:1961-4. 2010
    ..In a recent population-based case-control study using 2,400 cases of childhood cancer, we found a statistically significant association between residential radon and acute lymphoblastic leukemia risk...
  37. ncbi Interactions between the OGG1 Ser326Cys polymorphism and intake of fruit and vegetables in relation to lung cancer
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100, Copenhagen, Denmark
    Free Radic Res 40:885-91. 2006
    ..The same tendency was seen in relation to intake of fruit. There were no statistically significant interactions between the OGG1 polymorphism and smoking...
  38. doi Risk of cancer among workers exposed to trichloroethylene: analysis of three Nordic cohort studies
    Johnni Hansen
    Danish Cancer Society Research Center, Copenhagen, Denmark
    J Natl Cancer Inst 105:869-77. 2013
    ..Some epidemiologic studies have reported increased risk of cancer of the kidney, cervix, liver and biliary passages, non-Hodgkin lymphoma, and esophageal adenocarcinoma...
  39. ncbi OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study
    Lotte Hatt
    Institute of Public Health, Department of Environmental Health, Copenhagen, Denmark
    Mutat Res 639:45-54. 2008
    ..The results suggest that OGG1 mRNA levels should be regarded as a biomarker of exposure to oxidative stress with induction of DNA rather than a marker of inborn DNA repair capacity...
  40. pmc Diabetes incidence and long-term exposure to air pollution: a cohort study
    Zorana J Andersen
    1Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Diabetes Care 35:92-8. 2012
    ..We studied the association between long-term exposure to traffic-related air pollution and incidence of diabetes...
  41. doi Long-term exposure to air pollution and asthma hospitalisations in older adults: a cohort study
    Zorana Jovanovic Andersen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, Copenhagen 2100, Denmark
    Thorax 67:6-11. 2012
    ..Exposure to air pollution in early life contributes to the burden of childhood asthma, but it is not clear whether long-term exposure to air pollution can lead to asthma onset or progression in adulthood...
  42. ncbi No association between base excision repair gene polymorphisms and risk of lung cancer
    Ulla Vogel
    National Institute of Occupational Health, Copenhagen, Denmark
    Biochem Genet 42:453-60. 2004
    ..This is the first study of polymorphisms in base excision repair genes in relation to lung cancer among Danes...
  43. doi Predictors of adipose tissue concentrations of organochlorine pesticides in a general Danish population
    Elvira V Bräuner
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    J Expo Sci Environ Epidemiol 22:52-9. 2012
    ..Single determinants varied among the individual compounds, even within related chlordane residues, suggesting that organochlorine pesticides should not be treated as a homogenous group...
  44. pmc A haplotype of polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a Danish prospective case-cohort study
    Rikke D Hansen
    National Research Centre for the Working Environment, Lersø Parkallé 105, 2100 Copenhagen, Denmark
    BMC Cancer 8:54. 2008
    ....
  45. ncbi [Traffic-related air pollution at the place of residence and risk of cancer among children]
    Ole Raaschou-Nielsen
    Institut for Epidemiologisk Kraeftforskning, Kraeftens Bekaempelse, DK 2100 København
    Ugeskr Laeger 164:2283-7. 2002
    ..The hypothesis that exposure to traffic-related air pollution increases the risk of cancer developing during childhood was investigated...
  46. ncbi Physical activity and risk for lung cancer in a Danish cohort
    Helle Bak
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 116:439-44. 2005
    ..Higher levels of occupational physical activity had no protective effect; the lowest IRR was found for sitting work. Our study shows no convincing protective effect of physical activity on lung cancer risk...
  47. pmc A prospective study of organochlorines in adipose tissue and risk of non‑Hodgkin lymphoma
    Elvira Vaclavik Bräuner
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Environ Health Perspect 120:105-11. 2012
    ..Exposure to organochlorines has been examined as a potential risk factor for non-Hodgkin lymphoma (NHL), with inconsistent results that may be related to limited statistical power or to imprecise exposure measurements...
  48. ncbi Genetic polymorphisms in CYP1B1, GSTA1, NQO1 and NAT2 and the risk of lung cancer
    Mette Sørensen
    Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK 2100 Copenhagen O, Denmark
    Cancer Lett 221:185-90. 2005
    ..The NAT2 fast acetylator genotype seemed to be protective against lung cancer in light smokers (< or =20 cigarettes/day) and not among heavy smokers (>20 cigarettes/day)...
  49. ncbi Does insufficient adjustment for smoking explain the preventive effects of fruit and vegetables on lung cancer?
    Halla Skuladottir
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark
    Lung Cancer 45:1-10. 2004
    ..The observed inverse association between high intakes of plant food seems chiefly to be a real protective effect, and not solely due to residual confounding...
  50. doi Perfluorooctanoate and perfluorooctanesulfonate plasma levels and risk of cancer in the general Danish population
    Kirsten T Eriksen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, Copenhagen Ø, Denmark
    J Natl Cancer Inst 101:605-9. 2009
    ..99 to 1.93). Plasma concentrations of perfluorooctanoate and perfluorooctanesulfonate in the general Danish population appear not to be associated with risk of prostate, bladder, pancreatic, or liver cancer...
  51. ncbi Exposure of Danish workers to trichloroethylene, 1947-1989
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen
    Appl Occup Environ Hyg 17:693-703. 2002
    ..Epidemiological studies of health effects of TCE may benefit from evaluating potential risk within different strata of calendar time, number of company employees, sex, and type of industry...
  52. doi GPX1 Pro(198)Leu polymorphism, erythrocyte GPX activity, interaction with alcohol consumption and smoking, and risk of colorectal cancer
    Rikke Dalgaard Hansen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark
    Mutat Res 664:13-9. 2009
    ..Our results indicate that lifestyle-related oxidative stress may be a risk factor for colorectal cancer among subjects with a lowered defence...
  53. pmc Association between plasma PFOA and PFOS levels and total cholesterol in a middle-aged Danish population
    Kirsten T Eriksen
    Danish Cancer Society Research Center, Copenhagen, Denmark
    PLoS ONE 8:e56969. 2013
    ....
  54. ncbi The effect of occasional smoking on smoking-related cancers: in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Bine Kjøller Bjerregaard
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100, Copenhagen Ø, Denmark
    Cancer Causes Control 17:1305-9. 2006
    ..We have investigated the association between occasional smoking and cancer of the bladder, kidney, pancreas, upper aero-digestive tract and lung...
  55. ncbi Glutathione S-transferase T1 null-genotype is associated with an increased risk of lung cancer
    Mette Sørensen
    Institute of Cancer Epidemiology, The Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 110:219-24. 2004
    ..These results suggest that the GSTT1 null-genotype is associated with an increased risk of lung cancer, especially in younger individuals...
  56. pmc Exposure to ultrafine particles from ambient air and oxidative stress-induced DNA damage
    Elvira Vaclavik Bräuner
    Institute of Public Health, Department of Environmental and Occupational Health, University of Copenhagen, Copenhagen, Denmark
    Environ Health Perspect 115:1177-82. 2007
    ..Particulate matter, especially ultrafine particles (UFPs), may cause health effects through generation of oxidative stress, with resulting damage to DNA and other macromolecules...
  57. doi Determinants of plasma PFOA and PFOS levels among 652 Danish men
    Kirsten T Eriksen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Environ Sci Technol 45:8137-43. 2011
    ..Our finding of a higher body burden of PFOA and PFOS among never smokers also warrants further evaluation...
  58. ncbi Prospective study of interaction between alcohol, NSAID use and polymorphisms in genes involved in the inflammatory response in relation to risk of colorectal cancer
    Ulla Vogel
    National Research Centre for the Working Environment, Copenhagen, Denmark
    Mutat Res 624:88-100. 2007
    ..02). Moreover, an interaction between DLG5 R30Q and NSAID use was found (P for interaction=0.02). Our results do not suggest that inborn variations in the inflammatory response play any major role in risk of colorectal cancer...
  59. doi Predictors of polychlorinated biphenyl concentrations in adipose tissue in a general Danish population
    Elvira V Bräuner
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Environ Sci Technol 45:679-85. 2011
    ..Our results indicate that predictors of PCBs varied according to substitution group, suggesting that ortho-substituted groups should be analyzed separately...
  60. pmc Road traffic noise and incident myocardial infarction: a prospective cohort study
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    PLoS ONE 7:e39283. 2012
    ..Both road traffic noise and ambient air pollution have been associated with risk for ischemic heart disease, but only few inconsistent studies include both exposures...
  61. pmc Long-term exposure to road traffic noise and incident diabetes: a cohort study
    Mette Sørensen
    Danish Cancer Society Research Center, Copenhagen, Denmark
    Environ Health Perspect 121:217-22. 2013
    ..Objective: We investigated whether long-term exposure to residential road traffic noise is associated with an increased risk of diabetes...
  62. doi Road traffic noise and stroke: a prospective cohort study
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark
    Eur Heart J 32:737-44. 2011
    ..The aim of this study was to investigate the relation between exposure to road traffic noise and risk for stroke, which has not been studied before...
  63. ncbi Ambient particle source apportionment and daily hospital admissions among children and elderly in Copenhagen
    Zorana J Andersen
    Department of Biostatistics, Copenhagen University, Copenhagen, Denmark
    J Expo Sci Environ Epidemiol 17:625-36. 2007
    ..These novel results may merit future research of potential mechanism, whereas at present, no single PM(10) source can be attributed to all morbidity...
  64. ncbi A genetic polymorphism in prostaglandin synthase 2 (8473, T-->C) and the risk of lung cancer
    Mette Sørensen
    Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK 2100 Copenhagen O, Denmark
    Cancer Lett 226:49-54. 2005
    ..48 (0.19-1.22) in carriers of one variant allele and 0.21 (0.04-1.07) in carriers of two variant alleles, and a significant trend (P=0.04). These results indicate that PTGS2 could be implicated in the development of lung cancer...
  65. ncbi Tobacco smoke and bladder cancer--in the European Prospective Investigation into Cancer and Nutrition
    Bine Kjøller Bjerregaard
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 119:2412-6. 2006
    ....
  66. doi Effects of smoking and antioxidant micronutrients on risk of colorectal cancer
    Rikke Dalgaard Hansen
    Danish Cancer Society Research Center, Copenhagen, Denmark
    Clin Gastroenterol Hepatol 11:406-15.e3. 2013
    ....
  67. ncbi Urinary 1-hydroxypyrene in children living in city and rural residences in Denmark
    Ase Marie Hansen
    National Institute of Occupational Health, Copenhagen Ø, Denmark
    Sci Total Environ 347:98-105. 2005
    ..The present study aims to assess the biological uptake in children of polycyclic aromatic hydrocarbons measured as 1-hydroxypyrene in urine from children living in city and rural residences...
  68. doi Prospective study of NAT1 and NAT2 polymorphisms, tobacco smoking and meat consumption and risk of colorectal cancer
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark
    Cancer Lett 266:186-93. 2008
    ..However, smoking intensity increased CRC risk among carriers of both NAT1 and NAT2 fast. This indicates that N-acetylator status affects the relationship between smoking and CRC risk...
  69. doi Polymorphisms in inflammation genes, tobacco smoke and furred pets and wheeze in children
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden, Copenhagen, Denmark
    Pediatr Allergy Immunol 20:614-23. 2009
    ..Polymorphisms in IL-8 affected the association between pet-keeping and risk of wheeze. Polymorphisms in inflammation genes might affect the association between environmental exposures and risk of recurrent wheeze in early childhood...
  70. ncbi Organochlorines in Danish women: predictors of adipose tissue concentrations
    Elvira Vaclavik
    Institute of Cancer Epidemiology, Danish Cancer Society, 49 Strandboulevarden, DK 2100 Copenhagen, Denmark
    Environ Res 100:362-70. 2006
    ....
  71. pmc Arsenic in drinking-water and risk for cancer in Denmark
    Rikke Baastrup
    Danish Cancer Society, Institute of Cancer Epidemiology, Strandboulevarden 49, Copenhagen, Denmark
    Environ Health Perspect 116:231-7. 2008
    ..Epidemiologic studies have shown increased cancer risks among individuals exposed to high concentrations of arsenic in drinking-water, whereas studies of the carcinogenic effect of low doses have had inconsistent results...
  72. ncbi Urinary 1-hydroxypyrene in children living in city and rural residences in Denmark
    Ase Marie Hansen
    National Institute of Occupational Health, Copenhagen, Denmark
    Sci Total Environ 363:70-7. 2006
    ..The present study aims to assess the biological uptake in children of polycyclic aromatic hydrocarbons measured as 1-hydroxypyrene in urine from children living in city and rural residences...
  73. ncbi Air pollution and childhood cancer: a review of the epidemiological literature
    Ole Raaschou-Nielsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen Ø
    Int J Cancer 118:2920-9. 2006
    ..In particular, nondifferential misclassification of exposure might have masked true, weak associations...
  74. doi Association between short-term exposure to ultrafine particles and hospital admissions for stroke in Copenhagen, Denmark
    Zorana Jovanovic Andersen
    The Danish Cancer Society, Institute of Cancer Epidemiology, Strandboulevarden 49, 2100 Copenhagen, Denmark
    Eur Heart J 31:2034-40. 2010
    ....
  75. doi Non-occupational exposure to paint fumes during pregnancy and fetal growth in a general population
    Mette Sørensen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark
    Environ Res 110:383-7. 2010
    ..Our results suggest that there are no causal relationship between non-occupational exposure to paint fumes in the residence during pregnancy and fetal growth...
  76. pmc Risk for leukaemia and brain and breast cancer among Danish utility workers: a second follow-up
    Christoffer Johansen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK 2100 Copenhagen, Denmark
    Occup Environ Med 64:782-4. 2007
    ..To update a study of risks for leukaemia, brain cancer and breast cancer in a Danish nationwide, population-based cohort of utility employees...
  77. doi Occurrence of organochlorine pesticides in indoor dust
    Elvira V Bräuner
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen Ø, Denmark
    J Environ Monit 13:522-6. 2011
    ..This raises concern and further large scale investigations are warranted to confirm this...
  78. doi Social inequality and incidence of and survival from cancers of the kidney and urinary bladder in a population-based study in Denmark, 1994-2003
    Kirsten Thorup Eriksen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK 2100 Copenhagen Ø, Denmark
    Eur J Cancer 44:2030-42. 2008
    ..We also found a moderate pattern of better survival from cancers at both sites in the most advantaged groups, most clearly reflected by the level of education, disposable income and affiliation to the work market...
  79. pmc Cancer in first-degree relatives and risk of testicular cancer in Denmark
    Rikke Baastrup Nordsborg
    Institute of Cancer Epidemiology, The Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 129:2485-91. 2011
    ..The familial aggregation of testicular and possibly other cancers may be explained by shared genes and/or shared environmental factors, but the mutual importance of each of these is difficult to determine...
  80. ncbi Validation of a job-exposure matrix for assessment of utility worker exposure to magnetic fields
    Christoffer Johansen
    Institute of Cancer Epidemiology, The Danish Cancer Society, Copenhagen
    Appl Occup Environ Hyg 17:304-10. 2002
    ..If the sample size in extreme categories provides enough power, a study in which this job-exposure matrix is used should allow detection of a true association between exposure to 50-Hz magnetic field and disease...
  81. ncbi ERCC1, XPD and RAI mRNA levels in lymphocytes are not associated with lung cancer risk in a prospective study of Danes
    Ulla Vogel
    National Institute of Occupational Health, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    Mutat Res 593:88-96. 2006
    ..41) for ERCC1, 1.00 (CI=0.83-1.21) for XPD and 1.25 (0.89-1.74) for RAI. In conclusion, this study indicated no association between mRNA expression of the DNA-repair genes ERCC1 and XPD and risk of subsequent development of lung cancer...
  82. doi DNA adducts and cancer risk in prospective studies: a pooled analysis and a meta-analysis
    Fabrizio Veglia
    Life Sciences and Epidemiology Unit, ISI Foundation, Torino 10133, Italy
    Carcinogenesis 29:932-6. 2008
    ..The results of our pooled and meta-analyses suggest that bulky DNA adducts are associated with lung cancer arising in current smokers after a follow-up of several years...
  83. ncbi Combinations of polymorphisms in XPD, XPC and XPA in relation to risk of lung cancer
    Ulla Vogel
    National Institute of Occupational Health, Lersoe Parkalle 105, DK 2100 Copenhagen O, Denmark
    Cancer Lett 222:67-74. 2005
    ..We found that XPA A23G and XPC Lys939Gln polymorphisms may be risk factors for lung cancer and evidence that positive interactions between the polymorphisms in XPA/XPD and XPC/XPD may occur...
  84. ncbi Personal exposure to PM2.5, black smoke and NO2 in Copenhagen: relationship to bedroom and outdoor concentrations covering seasonal variation
    Mette Sørensen
    Institute of Public Health, University of Copenhagen, Denmark
    J Expo Anal Environ Epidemiol 15:413-22. 2005
    ..5), BS and NO(2) depends on many factors besides the outdoor levels, and that information on, for example, time of season or outdoor temperature and residence exposure, could improve the accuracy of the personal exposure estimation...
  85. ncbi Air pollution and risk of lung cancer in a prospective study in Europe
    Paolo Vineis
    Imperial College London, London, UK
    Int J Cancer 119:169-74. 2006
    ..The association with NO(2) did not change after adjustment by cotinine and additional potential confounders, including occupational exposures. No clear association was found with other pollutants...
  86. ncbi Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer
    Ulla Vogel
    National Institute of Occupational Health, DK 2100 Copenhagen O, Denmark
    Mutat Res 546:65-74. 2004
    ..We found no interaction between genotypes and duration of smoking. In conclusion, two regions of chromosome 19q13.2-3 seem to be associated with risk of lung cancer...
  87. doi Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study
    Ulla Vogel
    National Research Centre for the Working Environment, DK 2100 Copenhagen O, Denmark
    Mutat Res 639:89-100. 2008
    ..p for interaction was 3 x 10(-6) for COX-2 A-1195G and 9 x 10(-5) for PPARgamma2 Pro(12)Ala. The results suggest that NSAID use may modify risk of lung cancer differently depending on the genotype...
  88. ncbi Air pollution from traffic and schizophrenia risk
    Carsten Bøcker Pedersen
    Schizophr Res 66:83-5. 2004
  89. ncbi [Effects of traffic-generated ultrafine particles on health]
    Marie Louise Vrang
    Afdeling for Miljø og Arbejdsmedicin, Institut for Folkesundhedsvidenskab, Københavns Universitet, Blegdamsvej 3, DK 2200 København N
    Ugeskr Laeger 164:3937-41. 2002
    ..Inhalation of particulate matter, especially ultrafine particles, causes oxidative stress and inflammation in lung tissue, which affects the lung cells per se, as well as the cardiovascular system...
  90. ncbi Prospective study of urinary excretion of 7-methylguanine and the risk of lung cancer: Effect modification by mu class glutathione-S-transferases
    Steffen Loft
    Department of Environmental and Occupational Health, University of Copenhagen, Denmark
    Int J Cancer 121:1579-84. 2007
    ..The finding of an association between m(7)Gua excretion and lung cancer risk mainly among current smokers and subjects with GSTM1 null genotype supports causality in this respect...
  91. ncbi Physical activity and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition Cohort
    Karen Steindorf
    Unit of Environmental Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Int J Cancer 119:2389-97. 2006
    ..It can be assumed that the elevated risks found for occupational physical activity are not produced mechanistically by physical activity itself but rather reflect exposure to occupation-related lung cancer risk factors...
  92. ncbi Gene-environment interactions between smoking and a haplotype of RAI, ASE-1 and ERCC1 polymorphisms among women in relation to risk of lung cancer in a population-based study
    Ulla Vogel
    National Institute of Occupational Health, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    Cancer Lett 247:159-65. 2007
    ..At high smoking intensity (>20g tobacco/day), there was only additional risk of smoking intensity among women who were homozygous carriers of the haplotype (IRR=2.03; 95% CI: 1.10-3.73 per 5 additional g tobacco/day)...
  93. ncbi Prediction of 222Rn in Danish dwellings using geology and house construction information from central databases
    Claus E Andersen
    Risø National Laboratory, DK 4000 Roskilde, Denmark
    Radiat Prot Dosimetry 123:83-94. 2007
    ..0 (one standard deviation). The comparison with the independent test data shows that the model makes sound predictions and that errors of radon predictions are only weakly correlated with the estimates themselves (R(2) = 10%)...
  94. ncbi Bulky DNA adducts as risk indicators of lung cancer in a Danish case-cohort study
    Ole Raaschou-Nielsen
    Int J Cancer 120:212-3. 2007
  95. ncbi Fruit and vegetable consumption and lymphoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Sabine Rohrmann
    Division of Clinical Epidemiology C020, German Cancer Research Centre, Im Neuenheimer Feld 280, Heidelberg, 69120, Germany
    Cancer Causes Control 18:537-49. 2007
    ..The best-established risk factors are related to dys-regulation of immune function, and evidence suggests that factors such as dietary or lifestyle habits may be involved in the etiology...
  96. ncbi Prospective study of 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and the risk of lung cancer
    Steffen Loft
    Department of Environmental and Occupational Health, University of Copenhagen, Denmark
    Carcinogenesis 27:1245-50. 2006
    ..8 (1.21-115) per doubling of 8-oxodG excretion. The association between 8-oxodG excretion and lung cancer risk among never-smokers suggests that oxidative damage to DNA nucleotides is important in this group...
  97. ncbi Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study
    Gitte Ravn-Haren
    Department of Toxicology and Risk Assessment, Danish Institute for Food and Veterinary Research, Søborg, Denmark
    Carcinogenesis 27:820-5. 2006
    ..Results from this prospective study suggest that the GPX1 Pro198Leu-associated lowered GPX activity is associated with higher breast cancer risk among Danish women...
  98. ncbi [Central nervous system tumours in children. An evaluation of the completeness and validity of the Cancer Registry]
    Rikke Thorsteinsson
    Kraeftens Bekaempelse, København
    Ugeskr Laeger 167:3782-5. 2005
    ..The aim of this study was to evaluate the registration of childhood CNS tumours in the Danish Cancer Registry (CR) from 1980 to 1996, based on completeness and validity...
  99. ncbi DNA adducts and lung cancer risk: a prospective study
    Marco Peluso
    Cancer Risk Factor Branch, CSPO Scientific Institute of Tuscany Region, Florence, Italy
    Cancer Res 65:8042-8. 2005
    ..Our prospective study suggests that leukocyte DNA adducts may predict lung cancer risk of never-smokers. Besides, the association of DNA adduct levels with O3 indicates a possible role for photochemical smog in determining DNA damage...
  100. ncbi Occupational exposures, environmental tobacco smoke, and lung cancer
    Fabrizio Veglia
    Institute for Scientific Interchange ISI Foundation, Turin, Italy
    Epidemiology 18:769-75. 2007
    ..We have studied the association between 52 high-risk job titles and lung cancer incidence in a large prospective study, with more than 200,000 participants followed for more than 6 years and 809 incident cases of lung cancer...
  101. ncbi XRCC3 polymorphisms and risk of lung cancer
    Nicklas R Jacobsen
    National Institute of Occupational Health, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    Cancer Lett 213:67-72. 2004
    ..34-14.96) times higher risk of lung cancer compared with homozygous carriers of the wild type allele. Our results indicate that XRCC3 IVS6 C1571T and the associated haplotype AAC are associated with relatively high risk of lung cancer...