Julio E Celis
Affiliation: Danish Cancer Society
Celis J, Moreira J, Gromova I, Cabezon T, Gromov P, Shen T, et al
. Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia. Mol Oncol. 2007;1:97-119 pubmed publisher
..These studies also revealed p53 positive, non-apocrine putative precancerous lesions as well as novel phenotypes for ME and some luminal cells characterized by the expression of cytokeratin 15. ..
Celis J, Gromov P, Moreira J, Cabezon T, Friis E, Vejborg I, et al
. Apocrine cysts of the breast: biomarkers, origin, enlargement, and relation with cancer phenotype. Mol Cell Proteomics. 2006;5:462-83 pubmed
Celis J, Gromov P, Cabezon T, Moreira J, Friis E, Jirstrom K, et al
. 15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma. Mol Cell Proteomics. 2008;7:1795-809 pubmed publisher
Celis J, Gromova I, Cabezon T, Gromov P, Shen T, Timmermans Wielenga V, et al
. Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease. Mol Oncol. 2007;1:321-49 pubmed publisher
Celis J, Cabezon T, Moreira J, Gromov P, Gromova I, Timmermans Wielenga V, et al
. Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort. Mol Oncol. 2009;3:220-37 pubmed publisher
..These results pave the way for addressing issues such as prognosis of IACs, patient stratification for targeted therapeutics, as well as research strategies for identifying novel therapeutic targets for developing new cancer therapies...