- The role of APOE polymorphisms in late-onset dementiasE H Corder
Odense University, Denmark
Cell Mol Life Sci 54:928-34. 1998..The association of both types of AD-related changes with the occurrence of epsilon 4 suggests that the APOE polymorphism causally contributes to the pathogenesis of AD...
- HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathyE H Corder
Genetic Epidemiology, Odense University, Denmark
Nat Med 4:1182-4. 1998..0001). Thus, neurologic symptoms for HIV-infection and AD are linked through an etiologic risk factor. Long-term survivors of HIV infection with E4 may be at high risk for AD; conversely, gene-viral interactions may speed AD pathogenesis...