Silvio Zaina

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. ncbi request reprint Insulin-like growth factor II and its receptors in atherosclerosis and in conditions predisposing to atherosclerosis
    Silvio Zaina
    Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
    Curr Opin Lipidol 14:483-9. 2003
  2. ncbi request reprint Nutrition and aberrant DNA methylation patterns in atherosclerosis: more than just hyperhomocysteinemia?
    Silvio Zaina
    Department of Clinical Biochemistry, Rigshospitalet, 2100 Copenhagen, Denmark
    J Nutr 135:5-8. 2005
  3. ncbi request reprint Insulin-like growth factor II plays a central role in atherosclerosis in a mouse model
    Silvio Zaina
    Experimental Cardiovascular Research, Wallenberg Laboratory, Department of Medicine, University of Lund, Malmo General Hospital, 205 02 Malmo, Sweden
    J Biol Chem 277:4505-11. 2002
  4. ncbi request reprint DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E
    Gertrud Lund
    Department of Plant Biochemistry, Royal Veterinary and Agricultural College, 1871 Frederiksberg, Denmark
    J Biol Chem 279:29147-54. 2004
  5. ncbi request reprint Shortened life span, bradycardia, and hypotension in mice with targeted expression of an Igf2 transgene in smooth muscle cells
    Silvio Zaina
    Department of Medicine Experimental Cardiovascular Research, University of Lund, Malmo General Hospital, 205 02 Malmo, Sweden
    Endocrinology 144:2695-703. 2003
  6. pmc Duplication-dependent CG suppression of the seed storage protein genes of maize
    Gertrud Lund
    Plant Biochemistry Laboratory, Department of Plant Biology, The Royal Veterinary and Agricultural University, DK 1871 Frederiksberg C, Denmark
    Genetics 165:835-48. 2003
  7. ncbi request reprint Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting
    James Harper
    Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom
    Cancer Res 66:1940-8. 2006
  8. ncbi request reprint Atherosclerosis, lipids, inflammation and epigenetics
    Gertrud Lund
    Curr Opin Lipidol 18:699-701. 2007

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Insulin-like growth factor II and its receptors in atherosclerosis and in conditions predisposing to atherosclerosis
    Silvio Zaina
    Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
    Curr Opin Lipidol 14:483-9. 2003
    ..Here we discuss experimental evidence pointing to insulin-like growth factor II and its receptors as important players in cardiovascular diseases...
  2. ncbi request reprint Nutrition and aberrant DNA methylation patterns in atherosclerosis: more than just hyperhomocysteinemia?
    Silvio Zaina
    Department of Clinical Biochemistry, Rigshospitalet, 2100 Copenhagen, Denmark
    J Nutr 135:5-8. 2005
    ..These data have the potential to assist in the identification of preventive or therapeutic avenues for cardiovascular disease...
  3. ncbi request reprint Insulin-like growth factor II plays a central role in atherosclerosis in a mouse model
    Silvio Zaina
    Experimental Cardiovascular Research, Wallenberg Laboratory, Department of Medicine, University of Lund, Malmo General Hospital, 205 02 Malmo, Sweden
    J Biol Chem 277:4505-11. 2002
    ..These observations provide the first direct evidence for an atherogenic activity of insulin-like growth factor II in vivo...
  4. ncbi request reprint DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E
    Gertrud Lund
    Department of Plant Biochemistry, Royal Veterinary and Agricultural College, 1871 Frederiksberg, Denmark
    J Biol Chem 279:29147-54. 2004
    ..Taken together, our results unequivocally show that alterations in DNA methylation profiles are early markers of atherosclerosis in a mouse model and may play a causative role in atherogenesis...
  5. ncbi request reprint Shortened life span, bradycardia, and hypotension in mice with targeted expression of an Igf2 transgene in smooth muscle cells
    Silvio Zaina
    Department of Medicine Experimental Cardiovascular Research, University of Lund, Malmo General Hospital, 205 02 Malmo, Sweden
    Endocrinology 144:2695-703. 2003
    ..These observations are discussed in the light of the proposed therapeutic use of IGF2 in human cardiac diseases...
  6. pmc Duplication-dependent CG suppression of the seed storage protein genes of maize
    Gertrud Lund
    Plant Biochemistry Laboratory, Department of Plant Biology, The Royal Veterinary and Agricultural University, DK 1871 Frederiksberg C, Denmark
    Genetics 165:835-48. 2003
    ..Duplication-dependent CG depletion is likely to occur at other loci as duplicated MITEs and LTR elements, or elements inserted into duplicated gene regions, also exhibit CG depletion...
  7. ncbi request reprint Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting
    James Harper
    Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom
    Cancer Res 66:1940-8. 2006
    ..This evidence shows the functional potency of allelic dosage of an epigenetically regulated gene in cancer and supports the application of an IGF-II ligand-specific therapeutic intervention in colorectal cancer...
  8. ncbi request reprint Atherosclerosis, lipids, inflammation and epigenetics
    Gertrud Lund
    Curr Opin Lipidol 18:699-701. 2007