Maj Vinberg

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. doi request reprint Impairment of executive function and attention predicts onset of affective disorder in healthy high-risk twins
    Maj Vinberg
    Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Clin Psychiatry 74:e747-53. 2013
  2. doi request reprint Risk markers for affective disorder, a seven-years follow up study of a twin cohort at low and high risk for affective disorder
    Maj Vinberg
    Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Psychiatr Res 47:565-71. 2013
  3. doi request reprint Metabolic syndrome in a cohort of affectively ill patients, a naturalistic study
    Maj Vinberg
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, Copenhagen, Denmark
    Nord J Psychiatry 66:142-5. 2012
  4. doi request reprint No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment
    Jens Drachmann Bukh
    Department of Psychiatry, University Hospital of Copenhagen, Rigshospitalet, Denmark
    Eur Neuropsychopharmacol 20:327-35. 2010
  5. doi request reprint The effect of escitalopram versus placebo on perceived stress and salivary cortisol in healthy first-degree relatives of patients with depression-A randomised trial
    Ulla Knorr
    Psychiatric Centre Copenhagen, Rigshospitalet, Copenhagen University Hospital, Denmark
    Psychiatry Res 200:354-60. 2012
  6. doi request reprint Variations in 5-HTTLPR: relation to familiar risk of affective disorder, life events, neuroticism and cortisol
    Maj Vinberg
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Prog Neuropsychopharmacol Biol Psychiatry 34:86-91. 2010
  7. pmc Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression: a randomized trial
    Ulla Knorr
    Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
    PLoS ONE 7:e31980. 2012
  8. doi request reprint Does bereavement-related first episode depression differ from other kinds of first depressions?
    Lars Vedel Kessing
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Rigshospitalet, Copenhagen Ø, Denmark
    Soc Psychiatry Psychiatr Epidemiol 45:801-8. 2010
  9. doi request reprint Interaction between genetic polymorphisms and stressful life events in first episode depression
    Jens Drachmann Bukh
    Department of Psychiatry, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark
    J Affect Disord 119:107-15. 2009
  10. doi request reprint Is there a difference in subjective experience of cognitive function in patients with unipolar disorder versus bipolar disorder?
    Kamilla Miskowiak
    Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Nord J Psychiatry 66:389-95. 2012

Detail Information

Publications35

  1. doi request reprint Impairment of executive function and attention predicts onset of affective disorder in healthy high-risk twins
    Maj Vinberg
    Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Clin Psychiatry 74:e747-53. 2013
    ..To investigate whether measures of cognitive function can predict onset of affective disorder in individuals at heritable risk...
  2. doi request reprint Risk markers for affective disorder, a seven-years follow up study of a twin cohort at low and high risk for affective disorder
    Maj Vinberg
    Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Psychiatr Res 47:565-71. 2013
    ..Further, they seem to experience more LEs and to be more vulnerable to these...
  3. doi request reprint Metabolic syndrome in a cohort of affectively ill patients, a naturalistic study
    Maj Vinberg
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, Copenhagen, Denmark
    Nord J Psychiatry 66:142-5. 2012
    ..Patients with affective disorder have higher mortality not only because of their affective illness but also because of a higher risk of death from physical illness especially cardiovascular diseases...
  4. doi request reprint No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment
    Jens Drachmann Bukh
    Department of Psychiatry, University Hospital of Copenhagen, Rigshospitalet, Denmark
    Eur Neuropsychopharmacol 20:327-35. 2010
    ..We found no evidence that the effects of the genetic polymorphisms on treatment outcome were dependent on stressful life events experienced by the individual prior to onset of depression...
  5. doi request reprint The effect of escitalopram versus placebo on perceived stress and salivary cortisol in healthy first-degree relatives of patients with depression-A randomised trial
    Ulla Knorr
    Psychiatric Centre Copenhagen, Rigshospitalet, Copenhagen University Hospital, Denmark
    Psychiatry Res 200:354-60. 2012
    ..However, change in salivary cortisol was one out of multiple outcome measures. The results of the present trial do not refute salivary cortisol as a potential endophenotype for depression...
  6. doi request reprint Variations in 5-HTTLPR: relation to familiar risk of affective disorder, life events, neuroticism and cortisol
    Maj Vinberg
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Prog Neuropsychopharmacol Biol Psychiatry 34:86-91. 2010
    ..Variations in the serotonin transporter gene (5-HTTLPR) and stressful life events are associated with affective disorders...
  7. pmc Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression: a randomized trial
    Ulla Knorr
    Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
    PLoS ONE 7:e31980. 2012
    ..The present trial is the first to test the hypothesis that escitalopram may reduce neuroticism in healthy first-degree relatives of patients with major depressive disorder (MD)...
  8. doi request reprint Does bereavement-related first episode depression differ from other kinds of first depressions?
    Lars Vedel Kessing
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Rigshospitalet, Copenhagen Ø, Denmark
    Soc Psychiatry Psychiatr Epidemiol 45:801-8. 2010
    ..It has never been investigated whether first depression differs in patients who have experienced bereavement compared to patients who have not...
  9. doi request reprint Interaction between genetic polymorphisms and stressful life events in first episode depression
    Jens Drachmann Bukh
    Department of Psychiatry, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark
    J Affect Disord 119:107-15. 2009
    ..However, the results from previous studies of gene-environment interactions in depression are inconsistent and might be confounded by the history of depression among participants...
  10. doi request reprint Is there a difference in subjective experience of cognitive function in patients with unipolar disorder versus bipolar disorder?
    Kamilla Miskowiak
    Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Nord J Psychiatry 66:389-95. 2012
    ..However, patients' subjective experience of cognitive difficulties is poorly understood, and it is unclear whether BD and UD patients experience different cognitive difficulties...
  11. doi request reprint The BDNF Val66Met polymorphism: relation to familiar risk of affective disorder, BDNF levels and salivary cortisol
    Maj Vinberg
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Psychoneuroendocrinology 34:1380-9. 2009
    ..The aim of the present study was to investigate whether the BDNF Val66Met polymorphism is associated with a familiar risk of affective disorder and whether these genotypes affect whole blood BDNF level and salivary cortisol...
  12. doi request reprint Gender differences among patients with a single depressive episode
    Jens D Bukh
    Department of Psychiatry, University Hospital of Copenhagen, Rigshospitalet, Denmark
    Psychopathology 43:159-69. 2010
    ..The present study evaluated gender differences in sociodemographic, clinical and treatment variables among patients suffering exclusively from single-episode depression...
  13. doi request reprint The influence of comorbid personality disorder and neuroticism on treatment outcome in first episode depression
    Camilla Bock
    Department of Psychiatry, University Hospital of Copenhagen, Denmark
    Psychopathology 43:197-204. 2010
    ..It has never been investigated whether comorbid personality disorder or neuroticism predicts a poor treatment outcome in first episode depression...
  14. doi request reprint Salivary cortisol in unaffected twins discordant for affective disorder
    Maj Vinberg
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
    Psychiatry Res 161:292-301. 2008
    ..Future prospective family, high-risk and twin studies are needed to decide whether abnormalities in the HPA axis can be identified as an endophenotype of affective disorder...
  15. doi request reprint Coping styles in healthy individuals at risk of affective disorder
    Maj Vinberg
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
    J Nerv Ment Dis 198:39-44. 2010
    ..In conclusion, maladaptive coping style may represent a trait marker for mood disorder improving maladaptive coping styles may be a target for selective prevention focusing on subgroups at high risk of developing an affective disorder...
  16. doi request reprint Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events
    Eva Haastrup
    Department of Clinical Immunology, The Blood Bank, The National University Hospital, Copenhagen, Denmark
    J Affect Disord 136:134-8. 2012
    ..The proinflammatory cytokine interleukin-18 (IL-18) is less investigated in depression but highly relevant since it is produced by activated macrophages and expressed in the brain...
  17. doi request reprint Clinical utility of Standardised Assessment of Personality - Abbreviated Scale (SAPAS) among patients with first episode depression
    Jens Drachmann Bukh
    Psychiatric Center Copenhagen, Copenhagen, Denmark
    J Affect Disord 127:199-202. 2010
    ..However, the diagnosing of personality disorder can be lengthy and requires some training. Therefore, a brief screening interview for comorbid personality disorder among patients suffering from depression would be of clinical use...
  18. pmc Effects of erythropoietin on depressive symptoms and neurocognitive deficits in depression and bipolar disorder
    Kamilla W Miskowiak
    Clinic for Affective Disorders, Department of Psychiatry, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Trials 11:97. 2010
    ....
  19. doi request reprint Erythropoietin: a candidate treatment for mood symptoms and memory dysfunction in depression
    Kamilla W Miskowiak
    Clinic for Affective Disorders, Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet 6211, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Psychopharmacology (Berl) 219:687-98. 2012
    ..Erythropoietin (EPO) has neuroprotective and neurotrophic actions and improves cognitive function in animal models of acute and chronic neurodegenerative conditions and in patients with cognitive decline...
  20. pmc The effects of centralised and specialised combined pharmacological and psychological intervention compared with decentralised and non-specialised treatment in the early course of severe unipolar and bipolar affective disorders--design of two randomised c
    Lars Vedel Kessing
    Mood Disorder Clinic, Psychiatric Centre Copenhagen, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Trials 12:32. 2011
    ..It is not known whether centralised and specialised secondary care intervention initiated early after the onset of the diseases can prevent the progression and thereby improve the prognosis...
  21. pmc Escitalopram and neuroendocrine response in healthy first-degree relatives to depressed patients--a randomized placebo-controlled trial
    Ulla Knorr
    Department of Psychiatry Copenhagen, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 6:e21224. 2011
    ....
  22. ncbi request reprint Whole blood BDNF levels in healthy twins discordant for affective disorder: association to life events and neuroticism
    Viktorija Trajkovska
    Neurobiology Research Unit and Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Section 9201, Blegdamsvej 9, 2100 Copenhagen, Denmark
    J Affect Disord 108:165-9. 2008
    ..Depression has been associated with decreased blood BDNF concentrations; but it is unclear if low blood BDNF levels are a state or a trait marker of depression...
  23. doi request reprint Is there an association between subjective and objective measures of cognitive function in patients with affective disorders?
    Anne M Svendsen
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
    Nord J Psychiatry 66:248-53. 2012
    ..The relationship between subjectively experienced and objectively measured cognitive function is controversial with several studies reporting no correlation between subjective and objective deficits...
  24. doi request reprint Hippocampal volume changes in healthy subjects at risk of unipolar depression
    William F C Baare
    Danish Centre for Magnetic Resonance, MR Department, Hvidovre Hospital, University Hospital of Copenhagen, 2650 Hvidovre, Denmark
    J Psychiatr Res 44:655-62. 2010
    ..Further studies are needed to elucidate the role of (shared) environmental and genetic factors...
  25. doi request reprint Do stressful life events predict medical treatment outcome in first episode of depression?
    Camilla Bock
    Dept of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Copenhagen Ø, Denmark
    Soc Psychiatry Psychiatr Epidemiol 44:752-60. 2009
    ..It is unclear whether medical treatment outcome in first episode depression differ for patients with and without stressful life events prior to onset of depression...
  26. doi request reprint Differences in psychomotor activity in patients suffering from unipolar and bipolar affective disorder in the remitted or mild/moderate depressive state
    Maria Faurholt-Jepsen
    The Copenhagen Affective Disorder Clinic, Psychiatric Centre Copenhagen, Rigshospitalet, Denmark
    J Affect Disord 141:457-63. 2012
    ..Studies measuring differences in psychomotor activity between unipolar and bipolar disorder show divergent results and none have used a combined heart rate and movement monitor for measuring activity during free-living conditions...
  27. doi request reprint Salivary cortisol in depressed patients versus control persons: a systematic review and meta-analysis
    Ulla Knorr
    Department of Psychiatry, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark
    Psychoneuroendocrinology 35:1275-86. 2010
    ..Based on the available studies there is not firm evidence for a difference of salivary cortisol in depressed patients and control persons and salivary cortisol is unable to discriminate between persons with and without depression...
  28. ncbi request reprint Quality of life in unaffected twins discordant for affective disorder
    Maj Vinberg
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Affect Disord 99:133-8. 2007
    ..The disability and hardship associated with affective disorder is shared by the family members of affective patients and might affect the family member's quality of life...
  29. pmc Validity of the diagnosis of a single depressive episode in a case register
    Camilla Bock
    Department of Psychiatry, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
    Clin Pract Epidemiol Ment Health 5:4. 2009
    ..To validate the ICD-10 diagnosis of a single depressive episode as used in daily clinical psychiatric practice and as recorded in the Danish Psychiatric Central Research Register...
  30. doi request reprint State-related alterations of gene expression in bipolar disorder: a systematic review
    Klaus Munkholm
    Psychiatric Center Copenhagen, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Bipolar Disord 14:684-96. 2012
    ..This review therefore evaluated the evidence for whether gene expression in bipolar disorder is state or trait related...
  31. ncbi request reprint [Electronic monitoring of patients with bipolar affective disorder]
    Anne Sophie Jacoby
    Psykiatrisk Center København, Rigshospitalet, Afsnit 6233, Blegdamsvej 9, Copenhagen
    Ugeskr Laeger 174:2707-10. 2012
    ..Hence it is recommended, that controlled trials on the effect of electronic monitoring on patients' course of illness, level of function and quality of life are conducted...
  32. doi request reprint The effect of prolonged duration of untreated depression on antidepressant treatment outcome
    Jens Drachmann Bukh
    Department 6233, Blegdamsvej 9, Psychiatric Center Copenhagen, Rigshospitalet, University Hospital of Copenhagen, DK 2100 Copenhagen, Denmark
    J Affect Disord 145:42-8. 2013
    ..However, there is only sparse data concerning the influence of treatment delay on the outcome of mood disorders. The present study aimed to assess the effect of prolonged untreated depression on the outcome of antidepressant treatment...
  33. doi request reprint Cytokines in bipolar disorder vs. healthy control subjects: a systematic review and meta-analysis
    Klaus Munkholm
    Psychiatric Center Copenhagen, Rigshospitalet, University of Copenhagen, Denmark
    J Psychiatr Res 47:1119-33. 2013
    ..Our aim was to systematically review evidence of peripheral cytokine alterations in bipolar disorder integrating findings from various affective states...
  34. doi request reprint Cytokines in bipolar disorder: a systematic review and meta-analysis
    Klaus Munkholm
    Psychiatric Center Copenhagen, Rigshospitalet, University of Copenhagen, Denmark
    J Affect Disord 144:16-27. 2013
    ..Our objective was to systematically review evidence of cytokine alterations in bipolar disorder according to affective state...
  35. pmc Rationale and design of the participant, investigator, observer, and data-analyst-blinded randomized AGENDA trial on associations between gene-polymorphisms, endophenotypes for depression and antidepressive intervention: the effect of escitalopram versus
    Ulla Knorr
    Department of Psychiatry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Trials 10:66. 2009
    ..The primary outcome measure is the change in plasma cortisol in the dexamethasone-corticotrophin releasing hormone test from baseline to the end of intervention...