Lene Udby

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. ncbi An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology L 9322, Rigshospitalet, 9 Blegdamsvej, Copenhagen, Denmark
    J Immunol Methods 263:43-55. 2002
  2. ncbi Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology, Rigshospitalet, Copenhagen, Denmark
    J Leukoc Biol 72:462-9. 2002
  3. ncbi Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Biochemistry 43:12877-86. 2004
  4. ncbi Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract
    Lene Udby
    Granulocyte Research Laboratory 9322, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark
    J Androl 26:333-42. 2005
  5. doi Human CRISP-3 binds serum alpha(1)B-glycoprotein across species
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark
    Biochim Biophys Acta 1800:481-5. 2010
  6. pmc beta-Microseminoprotein binds CRISP-3 in human seminal plasma
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark
    Biochem Biophys Res Commun 333:555-61. 2005
  7. ncbi Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation
    Kim Theilgaard-Monch
    Granulocyte Research Laboratory Department of Hematology, Rigshospitalet, the Laboratory for Gene Therapy Research Department of Clinical Biochemistry, University of Copenhagen, Copenhagen Ø, Denmark
    Blood 108:353-61. 2006
  8. ncbi Prodefensins are matrix proteins of specific granules in human neutrophils
    Mikkel Faurschou
    Department of Hematology, Rigshospitalet 4042, DK 2100 Copenhagen, Denmark
    J Leukoc Biol 78:785-93. 2005
  9. ncbi Subcellular fractionation of human neutrophils and analysis of subcellular markers
    Lene Udby
    Department of Hematology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    Methods Mol Biol 412:35-56. 2007
  10. ncbi Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils
    Kim Theilgaard-Monch
    Granulocyte Research Laboratory, Department of Hematology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark
    J Leukoc Biol 78:462-70. 2005

Collaborators

Detail Information

Publications14

  1. ncbi An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology L 9322, Rigshospitalet, 9 Blegdamsvej, Copenhagen, Denmark
    J Immunol Methods 263:43-55. 2002
    ..8 microg/ml), seminal plasma (11.2 microg/ml), and sweat (0.15 microg/ml), and describe the coexistence of two different molecular weight forms of CRISP-3, representing an N-glycosylated and a non-glycosylated form of the mature protein...
  2. ncbi Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology, Rigshospitalet, Copenhagen, Denmark
    J Leukoc Biol 72:462-9. 2002
    ..The presence of CRISP-3 in peroxidase-negative granules of neutrophils, in granules of eosinophils, and in exocrine secretions indicates a role in the innate host defense...
  3. ncbi Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Biochemistry 43:12877-86. 2004
    ..We suggest that the A1BG-CRISP-3 complex displays a similar function in protecting the circulation from a potentially harmful effect of free CRISP-3...
  4. ncbi Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract
    Lene Udby
    Granulocyte Research Laboratory 9322, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark
    J Androl 26:333-42. 2005
    ..Examination of seminal plasma from vasectomized males indicates that organs downstream of the epididymis are probably the major sources of seminal plasma CRISP-3...
  5. doi Human CRISP-3 binds serum alpha(1)B-glycoprotein across species
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark
    Biochim Biophys Acta 1800:481-5. 2010
    ..Since animal sera are often used to supplement buffers in experiments, in particular such that involve cell cultures, binding proteins present in sera might interfere in the experiments...
  6. pmc beta-Microseminoprotein binds CRISP-3 in human seminal plasma
    Lene Udby
    Granulocyte Research Laboratory, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark
    Biochem Biophys Res Commun 333:555-61. 2005
    ..Structural similarity with an MSP-binding protein from blood plasma suggests that CRISP-3 binds MSP through its aminoterminal SCP-domain...
  7. ncbi Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation
    Kim Theilgaard-Monch
    Granulocyte Research Laboratory Department of Hematology, Rigshospitalet, the Laboratory for Gene Therapy Research Department of Clinical Biochemistry, University of Copenhagen, Copenhagen Ø, Denmark
    Blood 108:353-61. 2006
    ..Hence, neutrophil-derived Hp might reduce tissue damage and bacterial growth at sites of infection or injury by propagating anti-inflammatory activities and Hb clearance...
  8. ncbi Prodefensins are matrix proteins of specific granules in human neutrophils
    Mikkel Faurschou
    Department of Hematology, Rigshospitalet 4042, DK 2100 Copenhagen, Denmark
    J Leukoc Biol 78:785-93. 2005
    ..Thus, human neutrophils not only store large amounts of mature defensins in azurophil granules but also contain a more easily mobilized reservoir of unprocessed prodefensins in specific granules...
  9. ncbi Subcellular fractionation of human neutrophils and analysis of subcellular markers
    Lene Udby
    Department of Hematology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    Methods Mol Biol 412:35-56. 2007
    ..Immunological methods (sandwich enzyme-linked immunosorbent assays) are used for quantitation of proteins that are characteristic constituents of the granule subsets of neutrophils...
  10. ncbi Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils
    Kim Theilgaard-Monch
    Granulocyte Research Laboratory, Department of Hematology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark
    J Leukoc Biol 78:462-70. 2005
    ..Hence, neutrophils, which constitute the first line of defense, are likely to serve as the primary local source of AGP at sites of infection or injury...
  11. ncbi Immunohistochemical detection of cysteine-rich secretory protein 3 in tissue and in serum from men with cancer or benign enlargement of the prostate gland
    Anders Bjartell
    Department of Urology, Malmo University Hospital, Lund University, Malmo, Sweden
    Prostate 66:591-603. 2006
    ..The current aims were to investigate diagnostic use of tissue expression and immunodetection in serum of CRISP-3 for detection or monitoring of PCa...
  12. pmc Association of cysteine-rich secretory protein 3 and beta-microseminoprotein with outcome after radical prostatectomy
    Anders S Bjartell
    Departments of Surgery Urology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 13:4130-8. 2007
    ..We investigated whether these markers are related to biochemical recurrence and whether addition of the markers improves prediction of recurring disease...
  13. ncbi Low salivary dehydroepiandrosterone and androgen-regulated cysteine-rich secretory protein 3 levels in Sjögren's syndrome
    Mikael Laine
    Helsinki University Central Hospital, and University of Helsinki, FIN 00029 HUS, Helsinki, Finland
    Arthritis Rheum 56:2575-84. 2007
    ..We undertook this study to test the hypothesis that SS is characterized by an insufficient androgen effect at the target tissue level...
  14. ncbi Identification of the presenilins in hematopoietic cells with localization of presenilin 1 to neutrophil and platelet granules
    Zeljka Korade Mirinics
    Department of Pediatrics, University of Pittsburgh School of Medicine, Pennsylvania 15261, USA
    Blood Cells Mol Dis 28:28-38. 2002
    ..These studies indicate that PS1 may play multiple roles in blood cell physiology and that blood tissue may provide a model to study PS1 interactions with other proteins...