J P Thyssen

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. ncbi 10-year prevalence of contact allergy in the general population in Denmark estimated through the CE-DUR method
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermatology, Gentofte University Hospital, 1 2820 Gentofte, Denmark
    Contact Dermatitis 57:265-72. 2007
  2. doi Metal allergy--a review on exposures, penetration, genetics, prevalence, and clinical implications
    Jacob P Thyssen
    National Allergy Research Centre and Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Chem Res Toxicol 23:309-18. 2010
  3. doi Characteristics of nickel-allergic dermatitis patients seen in private dermatology clinics in Denmark: a questionnaire study
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre Department of Dermatology and Allergology, Gentofte University Hospital Ledreborg Allé 40, 1 DK 2820 Gentofte, Denmark
    Acta Derm Venereol 89:384-8. 2009
  4. ncbi The epidemiology of contact allergy. Allergen exposure and recent trends
    J P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, University of Copenhagen, Gentofte Hospital, Denmark
    G Ital Dermatol Venereol 144:507-14. 2009
  5. doi The effect of tobacco smoking and alcohol consumption on the prevalence of self-reported hand eczema: a cross-sectional population-based study
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Hellerup, Gentofte, Denmark
    Br J Dermatol 162:619-26. 2010
  6. pmc A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study
    Jacob P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, Copenhagen, Denmark
    BMJ Open 1:e000062. 2011
  7. doi Xerosis is associated with atopic dermatitis, hand eczema and contact sensitization independent of filaggrin gene mutations
    Jacob P Thyssen
    National Allergy Research Centre, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Acta Derm Venereol 93:406-10. 2013
  8. ncbi Cobalt sensitization and dermatitis: considerations for the clinician
    Jacob P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, Hellerup, Gentofte, Denmark
    Dermatitis 23:203-9. 2012
  9. doi Contact sensitization to common haptens is associated with atopic dermatitis: new insight
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Br J Dermatol 166:1255-61. 2012
  10. doi The association between contact sensitization and atopic disease by linkage of a clinical database and a nationwide patient registry
    J P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Allergy 67:1157-64. 2012

Detail Information

Publications59

  1. ncbi 10-year prevalence of contact allergy in the general population in Denmark estimated through the CE-DUR method
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermatology, Gentofte University Hospital, 1 2820 Gentofte, Denmark
    Contact Dermatitis 57:265-72. 2007
    ..This could probably be explained by a decrease in nickel allergy. The CE-DUR approach holds the potential of being an efficient and easy monitoring method of contact allergy prevalence...
  2. doi Metal allergy--a review on exposures, penetration, genetics, prevalence, and clinical implications
    Jacob P Thyssen
    National Allergy Research Centre and Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Chem Res Toxicol 23:309-18. 2010
    ..Furthermore, metal allergy has been associated with device failure following insertion of intracoronary stents, hip and knee prostheses, as well as other implants. This area is in need of more research...
  3. doi Characteristics of nickel-allergic dermatitis patients seen in private dermatology clinics in Denmark: a questionnaire study
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre Department of Dermatology and Allergology, Gentofte University Hospital Ledreborg Allé 40, 1 DK 2820 Gentofte, Denmark
    Acta Derm Venereol 89:384-8. 2009
    ..No new cases of metal dermatitis were identified after 1985. We conclude that nickel allergy has decreased among young females with dermatitis due to the nickel regulation...
  4. ncbi The epidemiology of contact allergy. Allergen exposure and recent trends
    J P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, University of Copenhagen, Gentofte Hospital, Denmark
    G Ital Dermatol Venereol 144:507-14. 2009
    ..Finally, the prevalence of thiuram allergy is decreasing as a result of improved rubber glove production...
  5. doi The effect of tobacco smoking and alcohol consumption on the prevalence of self-reported hand eczema: a cross-sectional population-based study
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Hellerup, Gentofte, Denmark
    Br J Dermatol 162:619-26. 2010
    ..It has been debated whether life-style factors such as tobacco smoking and alcohol consumption are associated with hand eczema...
  6. pmc A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study
    Jacob P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, Copenhagen, Denmark
    BMJ Open 1:e000062. 2011
    ..This finding was replicated when an independent sample of Danish patients with established type 2 diabetes was compared with control subjects from the general population...
  7. doi Xerosis is associated with atopic dermatitis, hand eczema and contact sensitization independent of filaggrin gene mutations
    Jacob P Thyssen
    National Allergy Research Centre, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Acta Derm Venereol 93:406-10. 2013
    ..These results suggest that generalized xerosis may increase the risk of common skin disorders. ..
  8. ncbi Cobalt sensitization and dermatitis: considerations for the clinician
    Jacob P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, Hellerup, Gentofte, Denmark
    Dermatitis 23:203-9. 2012
    ..Exposure data together with clinical data from metal workers heavily exposed to cobalt suggest that patch-test reactions are sometimes false positive and that patch testers should carefully evaluate their clinical relevance...
  9. doi Contact sensitization to common haptens is associated with atopic dermatitis: new insight
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Br J Dermatol 166:1255-61. 2012
    ..It has been much debated whether atopic dermatitis (AD) is associated with contact sensitization as past findings have been conflicting. A positive association might change our clinical practice...
  10. doi The association between contact sensitization and atopic disease by linkage of a clinical database and a nationwide patient registry
    J P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Allergy 67:1157-64. 2012
    ..The objective was to study the association between contact sensitization and, respectively, atopic dermatitis and asthma using clinical databases...
  11. doi Atopic diseases by filaggrin mutations and birth year
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Allergy 67:705-8. 2012
    ..Filaggrin loss-of-function mutations are common and associated with atopic disorders. We investigated whether the prevalence of filaggrin mutations increased in different birth cohorts in adults from the general population in Denmark...
  12. doi The filaggrin null genotypes R501X and 2282del4 seem not to be associated with psoriasis: results from general population study and meta-analysis
    J P Thyssen
    National Allergy Research Centre Department of Dermato Allergology, Copenhagen University Hospital Gentofte, Denmark
    J Eur Acad Dermatol Venereol 26:782-4. 2012
    ..So far five relatively small patient-based case-control studies have rejected a possible association between psoriasis and the two most prevalent filaggrin null mutations, 2282del4 and R501X...
  13. doi Self-testing for contact sensitization to hair dyes--scientific considerations and clinical concerns of an industry-led screening programme
    Jacob P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, Gentofte, Denmark
    Contact Dermatitis 66:300-11. 2012
    ..If the use of a hair dye self-test to predict contact sensitization becomes widespread, there is severe risk that a tool has been marketed that may cause morbidity in European consumers...
  14. doi Chromium in leather footwear - risk assessment of chromium allergy and dermatitis
    Jacob P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, DK 2900 Hellerup, Denmark
    Contact Dermatitis 66:279-85. 2012
    ..Chromium-tanned leather footwear, which releases >3 ppm hexavalent Cr(VI), may pose a risk of sensitizing and eliciting allergic dermatitis...
  15. doi Individuals who are homozygous for the 2282del4 and R501X filaggrin null mutations do not always develop dermatitis and complete long-term remission is possible
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Denmark
    J Eur Acad Dermatol Venereol 26:386-9. 2012
    ..No studies have investigated whether individuals with the homozygous filaggrin null genotype always develop dermatitis...
  16. doi Cobalt release from implants and consumer items and characteristics of cobalt sensitized patients with dermatitis
    Jacob P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, University of Copenhagen, DK 2900 Hellerup, Denmark
    Contact Dermatitis 66:113-22. 2012
    ..Cobalt allergy is prevalent in dermatitis patients. Very little documentation exists about current sources of cobalt exposure...
  17. doi Filaggrin loss-of-function mutation R501X and 2282del4 carrier status is associated with fissured skin on the hands: results from a cross-sectional population study
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Br J Dermatol 166:46-53. 2012
    ....
  18. doi Assessment of nickel and cobalt release from 200 unused hand-held work tools for sale in Denmark - Sources of occupational metal contact dermatitis?
    Jacob P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, DK 2900 Hellerup, Denmark
    Sci Total Environ 409:4663-6. 2011
    ..Clinical relevance of metal exposure is usually assessed by the treating physician via the medical history and by presentation of allergic contact dermatitis...
  19. doi Cobalt release from inexpensive jewellery: has the use of cobalt replaced nickel following regulatory intervention?
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, DK 2900 Hellerup, Denmark
    Contact Dermatitis 63:70-6. 2010
    ..Before the introduction of the EU Nickel Directive, concern was raised that manufacturers of jewellery might turn from the use of nickel to cobalt following the regulatory intervention on nickel exposure...
  20. doi A spot test for detection of cobalt release - early experience and findings
    Jacob P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, 2820 Gentofte, Denmark
    Contact Dermatitis 63:63-9. 2010
    ..Cobalt-allergic patients may be unaware that they are exposed to cobalt from handling work items, causing hand dermatitis...
  21. doi Sensitivity and specificity of the nickel spot (dimethylglyoxime) test
    Jacob P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, Gentofte, Denmark
    Contact Dermatitis 62:279-88. 2010
    ..Because assessments according to EN 1811 are expensive to perform, time consuming, and may destruct the test item, it should be of great value to know the accuracy of the DMG screening test...
  22. doi Filaggrin null mutations increase the risk and persistence of hand eczema in subjects with atopic dermatitis: results from a general population study
    J P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Br J Dermatol 163:115-20. 2010
    ..Hand eczema is prevalent in the general population. It remains unclear whether or not filaggrin gene (FLG) null mutations increase the overall risk of hand eczema or only increase the risk of hand eczema in subjects with atopic dermatitis...
  23. doi The association between null mutations in the filaggrin gene and contact sensitization to nickel and other chemicals in the general population
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Br J Dermatol 162:1278-85. 2010
    ....
  24. doi Temporal trends of preservative allergy in Denmark (1985-2008)
    Jacob P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
    Contact Dermatitis 62:102-8. 2010
    ..In 1997, Alan Dillarstone predicted a stable development of preservative allergy following mandatory ingredient labelling on cosmetic products...
  25. doi Patch test reactivity to metal allergens following regulatory interventions: a 33-year retrospective study
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, DK 2900 Hellerup, Denmark
    Contact Dermatitis 63:102-6. 2010
    ..Contact allergy epidemics to chromate and nickel were addressed in Denmark in 1983 and 1990 by regulatory interventions...
  26. doi Identification of metallic items that caused nickel dermatitis in Danish patients
    Jacob P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, University of Copenhagen, Hellerup, Denmark
    Contact Dermatitis 63:151-6. 2010
    ..Nickel allergy is prevalent as assessed by epidemiological studies...
  27. doi Pragmatic approach to the clinical work-up of patients with putative allergic disease to metallic orthopaedic implants before and after surgery
    J P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Br J Dermatol 164:473-8. 2011
    ..We propose diagnostic criteria for allergic dermatitis reactions as well as noneczematous complications caused by metal implants...
  28. doi Excessive nickel release from earrings purchased from independent shops and street markets--a field study from Warsaw and London
    J P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    J Eur Acad Dermatol Venereol 25:1021-6. 2011
    ..Nickel allergy is frequent and cause morbidity and increased health care costs...
  29. doi The EU Nickel Directive revisited--future steps towards better protection against nickel allergy
    Jacob P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, DK 2820 Hellerup, Denmark
    Contact Dermatitis 64:121-5. 2011
    ..It is concluded that the EU Nickel Directive has started to change the epidemiology of nickel allergy in Europe but it should be revisited to better protect consumers and workers since nickel allergy and dermatitis remain very frequent...
  30. doi Prevalence of benzocaine and lidocaine patch test sensitivity in Denmark: temporal trends and relevance
    Jacob P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, University of Copenhagen, DK 2900 Hellerup, Denmark
    Contact Dermatitis 65:76-80. 2011
    ..Inclusion of local anaesthetics other than benzocaine in the baseline series has previously been debated...
  31. doi Hypersensitivity to local anaesthetics--update and proposal of evaluation algorithm
    Jacob Pontoppidan Thyssen
    Department of Dermatology, National Allergy Research Centre, Copenhagen, Dennmark
    Contact Dermatitis 59:69-78. 2008
    ..Based on the literature, the proposed algorithm may safely and rapidly distinguish between immediate-type and delayed-type allergic immune reactions...
  32. doi Contact allergy and human biomonitoring--an overview with a focus on metals
    Jacob P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, University of Copenhagen, DK 2900 Hellerup, Denmark
    Contact Dermatitis 65:125-37. 2011
    ..Also, there is a need for prospective studies, as all epidemiological studies so far have been cross-sectional...
  33. doi The epidemiology of hand eczema in the general population--prevalence and main findings
    Jacob P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Contact Dermatitis 62:75-87. 2010
    ..The aetiology of hand eczema is multifactorial and includes environmental as well as genetic factors. Future studies should focus on unresolved areas of hand eczema, for example, genetic predisposition...
  34. doi Effect of tobacco smoking and alcohol consumption on the prevalence of nickel sensitization and contact sensitization
    Jacob P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Gentofte Hospital, University of Copenhagen, DK 2900 Hellerup, Denmark
    Acta Derm Venereol 90:27-33. 2010
    ..50; CI=0.94-2.37) and current heavy smokers (OR=1.56; CI = 0.87-2.80) compared with never smokers. This study confirmed that smoking is associated with nickel sensitization, but rejected an association with alcohol consumption...
  35. pmc The association between metal allergy, total hip arthroplasty, and revision
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Copenhagen
    Acta Orthop 80:646-52. 2009
    ..Furthermore, we compared the prevalence of metal allergy in dermatitis patients with and without THA...
  36. doi Acceptable risk of contact allergy in the general population assessed by CE-DUR--a method to detect and categorize contact allergy epidemics based on patient data
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte University Hospital, DK 2820, Denmark
    Regul Toxicol Pharmacol 54:183-7. 2009
    ..5-8.0% and 2.5-10.4%, respectively. The reverse CE-DUR approach can be used to alert public health authorities if the estimated number of sensitized persons in the general population is above a certain threshold...
  37. doi Contact sensitization to fragrances in the general population: a Koch's approach may reveal the burden of disease
    J P Thyssen
    National Allergy Research Centre, Department of Dermatology and Allergology, Gentofte University Hospital, Gentofte, Denmark
    Br J Dermatol 160:729-35. 2009
    ..Contact sensitization to fragrance mix (FM) I and Myroxylon pereirae (MP) is common among European patients with dermatitis. Recently, FM II was included in the European baseline series as an additional marker of fragrance sensitization...
  38. doi Limonene hydroperoxide analogues differ in allergenic activity
    Johanna Bråred Christensson
    Dermatochemistry and Skin Allergy, Department of Chemistry, University of Gothenburg, SE 412 96 Gothenburg, Sweden
    Contact Dermatitis 59:344-52. 2008
    ..The fragrance terpene R-limonene is a very weak sensitizer but forms allergenic oxidation products upon contact with air. Oxidized (ox.) limonene is a frequent cause of contact allergy in clinical testing...
  39. doi Epidemiological data on consumer allergy to p-phenylenediamine
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermatology, Gentofte University Hospital, Ledreborg Alle 40, 1 Gentofte 2820, Denmark
    Contact Dermatitis 59:327-43. 2008
    ..Contact allergy to PPD is an important health issue for both women and men. More stringent regulation and enforcement are required as public health measures to reduce the burden of disease that exposure to PPD has brought to populations...
  40. doi Trends of contact allergy to fragrance mix I and Myroxylon pereirae among Danish eczema patients tested between 1985 and 2007
    Jacob P Thyssen
    Department of Dermatology, National Allergy Research Centre, Gentofte University Hospital, Ledreborg Alle 40, 1 2820 Gentofte, Denmark
    Contact Dermatitis 59:238-44. 2008
    ..Fragrance contact allergy has for long been recognized as an important health issue. In Denmark, the frequency of fragrance mix (FM) I contact allergy increased between 1985-1986 and 1997-1998 among male and female dermatitis patients...
  41. doi Drug-elicited systemic allergic (contact) dermatitis--update and possible pathomechanisms
    Jacob Pontoppidan Thyssen
    Department of Dermatology, National Allergy Research Centre, Gentofte University Hospital, Ledreborg Alle 40, 1 2820 Gentofte, Denmark
    Contact Dermatitis 59:195-202. 2008
    ..e. p-i concept) reactions are involved. As commonly used terms may be misleading because skin contact is not a prerequisite, we suggest that the term 'systemic allergic dermatitis' should be used in the future...
  42. doi The outcome of dimethylglyoxime testing in a sample of cell phones in Denmark
    Jacob Pontoppidan Thyssen
    Department of Dermatology, National Allergy Research Centre, Gentofte University Hospital, Ledreborg Alle 40, 1, 2820 Gentofte, Denmark
    Contact Dermatitis 59:38-42. 2008
    ..Because little is known about the frequency of nickel release from cell phones, it is difficult to estimate the risk of nickel sensitization and dermatitis among their users...
  43. doi Nickel release from earrings purchased in the United States: the San Francisco earring study
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermatology, Gentofte University Hospital, Gentofte, Denmark
    J Am Acad Dermatol 58:1000-5. 2008
    ..In Europe, decreasing prevalences of nickel sensitization are observed as a result of the European Union Nickel Directive. However, no directive exists in the United States...
  44. ncbi The epidemiology of contact allergy in the general population--prevalence and main findings
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermatology, Gentofte University Hospital, 1 2820 Gentofte, Denmark
    Contact Dermatitis 57:287-99. 2007
    ..Finally, heavy smoking was associated with contact allergy, mostly in women. Population-based epidemiological studies are considered a prerequisite in the surveillance of national and international contact allergy epidemics...
  45. doi p-Phenylenediamine sensitization is more prevalent in central and southern European patch test centres than in Scandinavian: results from a multicentre study
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, DK 2900 Hellerup, Denmark
    Contact Dermatitis 60:314-9. 2009
    ..Cross-sensitization to other contact allergens may occur. Because subjects sensitized to PPD are at risk of clinically severe reactions upon hair dyeing, there is a need for 'current' prevalence data on PPD sensitization...
  46. doi The prevalence and morbidity of sensitization to fragrance mix I in the general population
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, Hellerup 2900, Denmark
    Br J Dermatol 161:95-101. 2009
    ..The prevalence of sensitization to fragrance mix (FM) I and Myroxylon pereirae (MP, balsam of Peru) has decreased in recent years among Danish women with dermatitis...
  47. doi No association between nickel allergy and reporting cosmetic dermatitis from mascara or eye shadow: a cross-sectional general population study
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
    J Eur Acad Dermatol Venereol 24:722-5. 2010
    ..However, an association between nickel eyelid dermatitis and nickel in make-up products remains controversial...
  48. doi The association between hand eczema and nickel allergy has weakened among young women in the general population following the Danish nickel regulation: results from two cross-sectional studies
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, 2900 Hellerup Copenhagen, Denmark
    Contact Dermatitis 61:342-8. 2009
    ..An association between nickel contact allergy and hand eczema has previously been demonstrated. In 1990, Denmark regulated the extent of nickel release in the ear-piercing process as well as nickel release from consumer products...
  49. doi The prevalence of chromium allergy in Denmark is currently increasing as a result of leather exposure
    J P Thyssen
    Department of Dermato Allergology, National Allergy Research Centre, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
    Br J Dermatol 161:1288-93. 2009
    ..An effect from this intervention has previously been demonstrated among Danish construction workers...
  50. doi Prevalence of nickel and cobalt allergy among female patients with dermatitis before and after Danish government regulation: a 23-year retrospective study
    Jacob Pontoppidan Thyssen
    National Allergy Research Center, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
    J Am Acad Dermatol 61:799-805. 2009
    ..5 microg nickel/cm(2)/wk) from consumer products in 1990. Concomitant allergy to nickel and cobalt is often observed among patients with dermatitis, probably as a result of cosensitization...
  51. doi Nickel release from inexpensive jewelry and hair clasps purchased in an EU country - Are consumers sufficiently protected from nickel exposure?
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, 2900Hellerup, Denmark
    Sci Total Environ 407:5315-8. 2009
    ..Despite a decrease, the prevalence of nickel allergy remains high as nearly 10% of young women are nickel allergic...
  52. doi Contact allergy to allergens of the TRUE-test (panels 1 and 2) has decreased modestly in the general population
    J P Thyssen
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark
    Br J Dermatol 161:1124-9. 2009
    ..The prevalence of contact allergy in the general population is nearly 20%...
  53. doi Association between filaggrin null mutations and concomitant atopic dermatitis and contact allergy
    B C Carlsen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Clin Exp Dermatol 36:467-72. 2011
    ..The phenotypic traits of people with the filaggrin mutation (FLG) genotype and atopic dermatitis (AD) are still under elucidation, and the association with concomitant AD and contact allergy (CA) has not previously been examined...
  54. doi Inverse relationship between contact allergy and psoriasis: results from a patient- and a population-based study
    N Bangsgaard
    National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, DK 2900 Hellerup, Denmark
    Br J Dermatol 161:1119-23. 2009
    ..Psoriasis is an autoimmune disease and it has been debated whether contact allergy is less prevalent among patients with psoriasis. Previous studies have shown conflicting results...
  55. doi The role of glutathione S-transferase and claudin-1 gene polymorphisms in contact sensitization: a cross-sectional study
    K Ross-Hansen
    National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Br J Dermatol 168:762-70. 2013
    ..Contact sensitization is frequent in the general population and arises from excessive or repeated skin exposure to chemicals and metals. However, little is known about its genetic susceptibility...
  56. ncbi The association between alcohol consumption and contact sensitization in Danish adults: the Glostrup Allergy Study
    J P Thyssen
    National Allergy Research Centre, Department of Dermatology, Gentofte University Hospital, Ledreborg Allé 10, 1 2820 Gentofte, Denmark
    Br J Dermatol 158:306-12. 2008
    ..However, a possible association between contact sensitization and alcohol consumption in a general population has never been reported...
  57. ncbi Allergic reaction to hydroxyethylmethacrylate following intradermal filler injection
    J P Thyssen
    Department of Dermatology, University of Copenhagen, Gentofte Hospital, Niels Andersensvej 165, 2900 Hellerup, Denmark
    Contact Dermatitis 52:341-2. 2005
  58. ncbi Contact dermatitis from methylisothiazolinone in a paint factory
    J P Thyssen
    Department of Dermato venerology, Gentofte Hospital, University of Copenhagen, Niels Andersensvej 65, 2900 Hellerup, Denmark
    Contact Dermatitis 54:322-4. 2006
    ..Our data show that MI holds a potential for eliciting and propably inducing contact allergy in humans. Whether this preservative is safe to use in cosmetics where billions of consumers are exposed needs a care full monitoring...
  59. doi Improvement in psoriasis after treatment with the glucagon-like peptide-1 receptor agonist liraglutide
    A Faurschou
    Diabetes Research Division, Department of Internal Medicine F, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, 2900, Hellerup, Denmark
    Acta Diabetol 51:147-50. 2014
    ..Randomized clinical trials are needed to reveal whether GLP-1R agonists represent a new therapeutic option for psoriasis...