Thorkild I A Sørensen

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. pmc Advancing the future of physical activity guidelines in Canada: an independent expert panel interpretation of the evidence
    Antero Kesaniemi
    Institute of Clinical Medicine, Department of Internal Medicine and Biocenter Oulu, University of Oulu, PO Box 5000, FIN 90014, Finland
    Int J Behav Nutr Phys Act 7:41. 2010
  2. pmc Parental socioeconomic position and development of overweight in adolescence: longitudinal study of Danish adolescents
    Camilla Schmidt Morgen
    Institute of Public Health, University of Copenhagen, Denmark
    BMC Public Health 10:520. 2010
  3. pmc Genome wide association study identifies KCNMA1 contributing to human obesity
    Hong Jiao
    Department of Biosciences and Nutrition, Karolinska Institutet, SE 141 83 Huddinge, Sweden
    BMC Med Genomics 4:51. 2011
  4. pmc The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
    Malene Hornbak
    Marie Krogh Center for Metabolic Research, Section of Metabolic Genetics, Faculty of Health Sciences, University of Copenhagen, Denmark
    BMC Med Genet 12:4. 2011
  5. ncbi Obesity as a clinical and public health problem: is there a need for a new definition based on lipotoxicity effects?
    Thorkild I A Sørensen
    Institute of Preventive Medicine, Copenhagen University Hospitals, Copenhagen, Denmark
    Biochim Biophys Acta 1801:400-4. 2010
  6. doi Conference on "Multidisciplinary approaches to nutritional problems". Symposium on "Diabetes and health". Challenges in the study of causation of obesity
    Thorkild I A Sørensen
    Institute of Preventive Medicine, Copenhagen University Hospitals, Centre for Health and Society, Copenhagen DK1357K, Denmark
    Proc Nutr Soc 68:43-54. 2009
  7. doi N-3 polyunsaturated fatty acids, body fat and inflammation
    Anne Sofie Q Lund
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Obes Facts 6:369-79. 2013
  8. doi Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors
    Tanja Stocks
    Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals Part of the Copenhagen University Hospital, the Capital Region, Copenhagen, Denmark
    Obes Facts 6:217-27. 2013
  9. pmc Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men
    Esther Zimmermann
    Institute of Preventive Medicine, Copenhagen University Hospitals, Centre for Health and Society, Copenhagen, Denmark
    PLoS ONE 4:e4428. 2009
  10. ncbi Smallpox vaccination and all-cause infectious disease hospitalization: a Danish register-based cohort study
    Signe Sørup
    Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    Int J Epidemiol 40:955-63. 2011

Detail Information

Publications104 found, 100 shown here

  1. pmc Advancing the future of physical activity guidelines in Canada: an independent expert panel interpretation of the evidence
    Antero Kesaniemi
    Institute of Clinical Medicine, Department of Internal Medicine and Biocenter Oulu, University of Oulu, PO Box 5000, FIN 90014, Finland
    Int J Behav Nutr Phys Act 7:41. 2010
    ..The paper includes also their recommendations for evidence-informed physical activity guidelines...
  2. pmc Parental socioeconomic position and development of overweight in adolescence: longitudinal study of Danish adolescents
    Camilla Schmidt Morgen
    Institute of Public Health, University of Copenhagen, Denmark
    BMC Public Health 10:520. 2010
    ..The objective was to identify the possible association between parental socioeconomic position, weight change and the risk of developing overweight among adolescents between the ages 15 to 21...
  3. pmc Genome wide association study identifies KCNMA1 contributing to human obesity
    Hong Jiao
    Department of Biosciences and Nutrition, Karolinska Institutet, SE 141 83 Huddinge, Sweden
    BMC Med Genomics 4:51. 2011
    ..Thus many genetic variants controlling obesity remain to be identified. The aim of this study was to use GWA followed by multiple stepwise validations to identify additional genes associated with obesity...
  4. pmc The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
    Malene Hornbak
    Marie Krogh Center for Metabolic Research, Section of Metabolic Genetics, Faculty of Health Sciences, University of Copenhagen, Denmark
    BMC Med Genet 12:4. 2011
    ..We aimed to investigate whether the two variants associate with altered insulin release following an oral glucose load or with T2D...
  5. ncbi Obesity as a clinical and public health problem: is there a need for a new definition based on lipotoxicity effects?
    Thorkild I A Sørensen
    Institute of Preventive Medicine, Copenhagen University Hospitals, Copenhagen, Denmark
    Biochim Biophys Acta 1801:400-4. 2010
    ..This test would ideally be a single biomarker that would determine residual capacity for adipose expansion, fatty acid oxidation and safe ectopic lipid deposition...
  6. doi Conference on "Multidisciplinary approaches to nutritional problems". Symposium on "Diabetes and health". Challenges in the study of causation of obesity
    Thorkild I A Sørensen
    Institute of Preventive Medicine, Copenhagen University Hospitals, Centre for Health and Society, Copenhagen DK1357K, Denmark
    Proc Nutr Soc 68:43-54. 2009
    ....
  7. doi N-3 polyunsaturated fatty acids, body fat and inflammation
    Anne Sofie Q Lund
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Obes Facts 6:369-79. 2013
    ..We aimed to investigate if, among humans, intake of n-3 PUFAs was associated with i) total body fat, ii) body fat distribution and iii) obesity-related inflammatory markers...
  8. doi Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors
    Tanja Stocks
    Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals Part of the Copenhagen University Hospital, the Capital Region, Copenhagen, Denmark
    Obes Facts 6:217-27. 2013
    ..To investigate in a secondary analysis of a randomised trial the effects of a low-/high-fat diet and reported change from baseline in energy% from protein (prot%), in relation to changes in body size and metabolic factors...
  9. pmc Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men
    Esther Zimmermann
    Institute of Preventive Medicine, Copenhagen University Hospitals, Centre for Health and Society, Copenhagen, Denmark
    PLoS ONE 4:e4428. 2009
    ..The A-allele of the single nucleotide polymorphism (SNP), rs9939609, in the FTO gene is associated with increased fatness. We hypothesized that the SNP is associated with morbidity and mortality through the effect on fatness...
  10. ncbi Smallpox vaccination and all-cause infectious disease hospitalization: a Danish register-based cohort study
    Signe Sørup
    Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    Int J Epidemiol 40:955-63. 2011
    ..In Denmark, the live vaccine against smallpox was phased out in the 1970s due to the eradication of smallpox. We used the phasing-out period to investigate the effect of smallpox vaccination on the risk of hospitalization for infections...
  11. ncbi Past and current body size affect validity of reported energy intake among middle-aged Danish men
    Birgit M Nielsen
    Institute of Preventive Medicine, Copenhagen University Hospitals, Centre for Health and Society, Copenhagen, Denmark
    J Nutr 139:2337-43. 2009
    ..Thus, underreporting of dietary intake seems to be associated with not only current BMI but also with current BMI in combination with previous BMI...
  12. doi Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype
    Sofia Inez Iqbal Kring
    Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    Obes Facts 1:138-45. 2008
    ..In the present study, we assess the association of seven abdominal, peripheral, and overall obesity phenotypes, which were analyzed quantitatively, and thirteen candidate gene polymorphisms in these ten genes in the same cohort...
  13. pmc 24h urinary sodium excretion and subsequent change in weight, waist circumference and body composition
    Sofus C Larsen
    Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals, Copenhagen University Hospital, the Capital Region, Copenhagen, Denmark
    PLoS ONE 8:e69689. 2013
    ....
  14. pmc TFAP2B influences the effect of dietary fat on weight loss under energy restriction
    Tanja Stocks
    Institute of Preventive Medicine, Copenhagen University Hospital, Frederiksberg, Denmark
    PLoS ONE 7:e43212. 2012
    ..We investigated if 55 SNPs previously associated with BMI or waist measures, modify the effects of fat intake on weight loss and waist reduction under energy restriction...
  15. doi Weight gain in different periods of pregnancy and offspring's body mass index at 7 years of age
    Camilla Schou Andersen
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Int J Pediatr Obes 6:e179-86. 2011
    ..We investigated how average weekly gestational weight gain rates during three periods of pregnancy were related to the offspring's body mass index (BMI) at 7 years of age...
  16. doi Obesity research based on the Copenhagen School Health Records Register
    Jennifer L Baker
    Institute of Preventive Medicine, Øster Søgade 18, 1357 Copenhagen K, Denmark
    Scand J Public Health 39:196-200. 2011
    ..Additional information on the cohort members has been obtained via linkages with population studies and national registers...
  17. pmc Birth weight, childhood body mass index and risk of coronary heart disease in adults: combined historical cohort studies
    Lise Geisler Andersen
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 5:e14126. 2010
    ..We studied individual and combined associations of birth weight and childhood BMI with the risk of CHD in adulthood...
  18. pmc Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of body mass index
    Esther Zimmermann
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 6:e15958. 2011
    ..We aimed to investigate if this gene variant had fatness-independent effects on plasma hs-CRP and 10 additional circulating obesity-related adipokines throughout a broad range of body mass index (BMI) among Danish men...
  19. doi TFAP2B -dietary protein and glycemic index interactions and weight maintenance after weight loss in the DiOGenes trial
    Tanja Stocks
    Institute of Preventive Medicine, Bispebjerg and Frederiksberg University Hospital, Copenhagen, Denmark
    Hum Hered 75:213-9. 2013
    ..We investigated interactions between rs987237 and protein-to-carbohydrate ratio or glycemic index (GI) in relation to weight maintenance after weight loss...
  20. ncbi Increased risk of intestinal cancer in Crohn's disease: a meta-analysis of population-based cohort studies
    Tine Jess
    Department of Medical Gastroenterology C, Herlev University Hospital, Copenhagen, Denmark
    Am J Gastroenterol 100:2724-9. 2005
    ..The global CD population is growing and there is a demand for better knowledge of prognosis of this disease. Hence, the aim of the present study was to conduct a meta-analysis of population-based data on intestinal cancer risk in CD...
  21. doi Longitudinal analysis of leptin variation during weight regain after weight loss in obese children
    Jens Christian Holm
    Department of Pediatrics, Copenhagen University Hospital Glostrup, Copenhagen, Denmark
    Obes Facts 2:243-8. 2009
    ..This study assessed if lower than predicted serum leptin concentrations seen during weight loss persisted during weight regain, with possible implications for weight control...
  22. pmc Educational differences in postmenopausal breast cancer--quantifying indirect effects through health behaviors, body mass index and reproductive patterns
    Ulla Arthur Hvidtfeldt
    Social Medicine Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
    PLoS ONE 8:e78690. 2013
    ..Women of high educational level may be more vulnerable to physical inactivity compared to women of low educational level. ..
  23. doi How do pregnancy-related weight changes and breastfeeding relate to maternal weight and BMI-adjusted waist circumference 7 y after delivery? Results from a path analysis
    Helene Kirkegaard
    Department of Public Health, Section for Epidemiology HK, and the Department of Public Health, Biostatistics HS, Aarhus University, Aarhus, Denmark the Division of Nutritional Sciences, Cornell University, Ithaca, NY KMR the Division of Epidemiology, School of Public Health, University of California, Berkeley, CA BA the Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark TIAS the Institute of Preventive Medicine, Bispebjerg and Frederiksberg University Hospital, Capital Region, Copenhagen, Denmark TIAS and the Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark EAN
    Am J Clin Nutr 99:312-9. 2014
    ..However, the influence of weight changes during the whole reproductive cycle and the modifying effect of breastfeeding are unknown...
  24. ncbi Alcoholic beverage preference and risk of becoming a heavy drinker
    Majken K Jensen
    Copenhagen Centre for Prospective Population Studies, Danish Epidemiology Science Centre at the Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Epidemiology 13:127-32. 2002
    ..The aim of this study is to examine whether the risk of becoming a heavy or excessive drinker differs among individuals who prefer different types of alcoholic beverages...
  25. ncbi A prospective study of the association between smoking and later alcohol drinking in the general population
    Majken K Jensen
    Copenhagen Centre for Prospective Population Studies, Danish Epidemiology Science Centre at the Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Addiction 98:355-63. 2003
    ..To address the possible prospective association between smoking habits and risk of later heavy drinking in the adult population...
  26. ncbi Psychosocial and demographic determinants of regional differences in the prevalence of obesity
    Jytte Halkjaer
    Danish Epidemiology Science Centre, Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    J Biosoc Sci 36:141-52. 2004
    ..In conclusion, the regional differences in the prevalence of obesity could not be explained by birth place or later selective migration, but educational level and intelligence test score did explain some of the difference...
  27. doi Aetiological factors behind adipose tissue inflammation: an unexplored research area
    Bernt J von Scholten
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Public Health Nutr 16:27-35. 2013
    ..In the present narrative review we present potential determinants of adipose tissue inflammation and suggest ways ahead for future research in the field...
  28. pmc Increasing genetic variance of body mass index during the Swedish obesity epidemic
    Benjamin Rokholm
    Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    PLoS ONE 6:e27135. 2011
    ..We tested the hypothesis that the genetic variance of BMI has increased during the obesity epidemic...
  29. pmc Changes in waist circumference and the incidence of acute myocardial infarction in middle-aged men and women
    Tina Landsvig Berentzen
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 6:e26849. 2011
    ..We investigated the association between DWC and the risk of MI in middle-aged men and women, and evaluated the influence from concurrent changes in BMI (DBMI)...
  30. doi Twin study of heritability of eating bread in Danish and Finnish men and women
    Ann L Hasselbalch
    Institute of Preventive Medicine, Copenhagen Capital Region, Copenhagen University Hospitals, Centre for Health and Society, DK 1357 Copenhagen, Denmark
    Twin Res Hum Genet 13:163-7. 2010
    ..Environmental factors shared by the co-twins (e.g., childhood environment) seem to have no significant effects on bread consumption and preference in adulthood...
  31. doi A variant in the fat mass and obesity-associated gene (FTO) and variants near the melanocortin-4 receptor gene (MC4R) do not influence dietary intake
    Ann L Hasselbalch
    Institute of Preventive Medicine, Copenhagen Capital Region, Copenhagen University Hospitals, Centre for Health and Society, Copenhagen, Denmark
    J Nutr 140:831-4. 2010
    ..The outcome of this study indicates that polymorphisms in the FTO gene and near the MC4R gene do not have a role in regulating food intake and preference for specific food items...
  32. doi Common genetic components of obesity traits and serum leptin
    Ann L Hasselbalch
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Obesity (Silver Spring) 16:2723-9. 2008
    ....
  33. doi Studies based on the Danish Adoption Register: schizophrenia, BMI, smoking, and mortality in perspective
    Liselotte Petersen
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, DK 1357 Copenhagen K, Denmark
    Scand J Public Health 39:191-5. 2011
    ..The Danish Adoption Register includes information on all 14,425 non-familial adoptions of Danish children legally granted in Denmark from 1924 to 1947...
  34. pmc Body composition, dietary protein and body weight regulation. Reconciling conflicting results from intervention and observational studies?
    Mikkel Z Ankarfeldt
    Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, the Capital Region, Copenhagen, Denmark Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark
    PLoS ONE 9:e101134. 2014
    ..This study investigates whether the discrepancy in the evidence could be due to recruitment of overweight and obese individuals into clinical trials...
  35. ncbi A prospective study linked both alcohol and tobacco to Dupuytren's disease
    Nina S Godtfredsen
    Copenhagen Centre for Prospective Population Studies, Danish Epidemiology Science Centre, Institute of Preventive Medicine, Copenhagen University Hospital, Svanemøllevej 25, DK 2100 Copenhagen, Denmark
    J Clin Epidemiol 57:858-63. 2004
    ..To address the role of alcohol intake and tobacco smoking and the combination of the two on subsequent risk of Dupuytren's disease...
  36. ncbi Stability of the association between birth weight and childhood overweight during the development of the obesity epidemic
    Susi Rugholm
    Danish Epidemiology Science Centre, Institute of Preventive Medicine, Kommunehospitalet, Copenhagen, Denmark
    Obes Res 13:2187-94. 2005
    ..To assess whether changes in the birth weight distribution or changes in the association of birth weight with the later risk of childhood overweight have contributed to the development of the obesity epidemic...
  37. ncbi Birth cohort effect on the obesity epidemic in Denmark
    Lina W Olsen
    Danish Epidemiology Science Centre, Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Epidemiology 17:292-5. 2006
    ..In Denmark, the obesity epidemic has developed in phases. To investigate if this has been a birth cohort phenomenon, we explored the secular trend in the prevalence of obesity among boys and young men...
  38. ncbi Intelligence test score and educational level in relation to BMI changes and obesity
    Jytte Halkjaer
    Danish Epidemiology Science Centre at the Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Obes Res 11:1238-45. 2003
    ..To investigate whether intelligence and education are related to subsequent BMI changes and development and persistence of obesity in men from young adulthood through middle-age...
  39. ncbi Intelligence in relation to later beverage preference and alcohol intake
    Laust H Mortensen
    Danish Epidemiology Science Centre, Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Addiction 100:1445-52. 2005
    ..The health effects of drinking may be related to psychological characteristics influencing both health and drinking habits. This study aims to examine the relationship between intelligence, later beverage preference and alcohol intake...
  40. pmc Intention to lose weight, weight changes, and 18-y mortality in overweight individuals without co-morbidities
    Thorkild I A Sørensen
    Danish Epidemiology Science Centre, Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS Med 2:e171. 2005
    ..We investigated the influence on mortality of intention to lose weight and subsequent weight changes among overweight individuals without known co-morbidities...
  41. ncbi Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes
    Kristoffer Sølvsten Burgdorf
    Hagedorn Research Institute, Niels Steensens Vej 1, NLD 2 13, 2820 Gentofte, Copenhagen, Denmark
    Eur J Endocrinol 163:81-7. 2010
    ..Our aim was to validate the reported findings in the Danish population...
  42. doi A cross-sectional study on trans-fatty acids and risk markers of CHD among middle-aged men representing a broad range of BMI
    Birgit M Nielsen
    Institute of Preventive Medicine, Copenhagen University Hospitals, Copenhagen Capital Region, Øster Søgade 18, DK 1357 Copenhagen K, Denmark
    Br J Nutr 106:1245-52. 2011
    ....
  43. ncbi Alcohol drinking frequency in relation to subsequent changes in waist circumference
    Janne S Tolstrup
    Center for Alcohol Research, National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark
    Am J Clin Nutr 87:957-63. 2008
    ..Cross-sectional studies have reported a lower prevalence of abdominal obese persons among frequent drinkers than among nonfrequent drinkers...
  44. pmc Trends in prevalence of overweight and obesity in danish infants, children and adolescents--are we still on a plateau?
    Camilla Schmidt Morgen
    National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark
    PLoS ONE 8:e69860. 2013
    ..After the worldwide steep increase in child and adolescent overweight and obesity during the last decades, there is now evidence of a levelling off in the prevalence in many countries in the Western world...
  45. pmc Contributions of incidence and persistence to the prevalence of childhood obesity during the emerging epidemic in Denmark
    Lise Geisler Andersen
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 7:e42521. 2012
    ..We investigated whether increasing incidence and/or persistence during childhood drove the prevalence of childhood obesity during the emerging epidemic...
  46. pmc Assortative marriages by body mass index have increased simultaneously with the obesity epidemic
    Teresa A Ajslev
    Institute of Preventive Medicine, Copenhagen University Hospital Copenhagen, Denmark
    Front Genet 3:125. 2012
    ..Yet, there were assorted marriages between spouses with high BMI at age 13 years and the tendency increased alongside with the obesity epidemic which may increase the offsprings' predisposition to obesity...
  47. ncbi Risk of lymphoma and leukaemia after bacille Calmette-Guérin and smallpox vaccination: a Danish case-cohort study
    Marie Villumsen
    Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Øster Søgade 18, 1st Floor, DK 1357 Copenhagen K, Denmark
    Vaccine 27:6950-8. 2009
    ..81 (0.31-2.16); smallpox vaccination HR=1.32 (0.49-3.53)). The present study with very reliable vaccine history information indicates a beneficial effect of BCG vaccination on the risk of lymphomas...
  48. doi Dynamic path analysis in life-course epidemiology
    Michael Gamborg
    Institute of Preventive Medicine, Øster Søgade 18, DK 1357 Copenhagen K, Denmark
    Am J Epidemiol 173:1131-9. 2011
    ..In conclusion, dynamic path analysis is a flexible tool that by the decomposition of effects can be used to increase the understanding of mechanisms that underlie the etiology of chronic disease...
  49. pmc Associations between APOE variants and metabolic traits and the impact of psychological stress
    Sofia I Iqbal Kring
    Institute of Preventive Medicine, Copenhagen, Denmark
    PLoS ONE 6:e15745. 2011
    ....
  50. pmc FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness
    Sofia I I Kring
    Institute of Preventive Medicine, Copenhagen University Hospitals, Centre for Health and Society, Copenhagen, Denmark
    PLoS ONE 3:e2958. 2008
    ..We investigated the association of this SNP with abdominal and peripheral fatness and obesity-related metabolic traits in middle-aged men through a broad range of fatness present already in adolescence...
  51. doi Studies of twins indicate that genetics influence dietary intake
    Ann Louise Hasselbalch
    Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    J Nutr 138:2406-12. 2008
    ..Although the remaining nonshared environmental effects include measurement errors, there appears to be considerable potential for individually modifiable effects...
  52. doi Weight at birth and all-cause mortality in adulthood
    Jennifer L Baker
    Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    Epidemiology 19:197-203. 2008
    ..The overall impact of these opposing effects on mortality throughout the lifespan is unclear because causes of death change with age...
  53. ncbi Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes
    Lesli H Larsen
    Steno Diabetes Center and Hagedorn Research Institute, Copenhagen, Denmark
    Clin Biochem 38:420-4. 2005
    ..To investigate the preproghrelin gene for variants and their association with obesity and type 2 diabetes...
  54. ncbi Changes since 1980 in body mass index and the prevalence of overweight among inschooling children in Nuuk, Greenland
    Christina Schnohr
    Department of Social Medicine, The Panum Institute, Copenhagen, Denmark
    Int J Circumpolar Health 64:157-62. 2005
    ..The aim of the study was to examine the trends which have occurred during the past generation in body mass index (BMI) and in the prevalence of overweight and obesity among children in public schools in Nuuk, Greenland...
  55. pmc Forty years trends in timing of pubertal growth spurt in 157,000 Danish school children
    Lise Aksglaede
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    PLoS ONE 3:e2728. 2008
    ..The aim of our study was to determine if the age at onset of pubertal growth spurt (OGS) and at peak height velocity (PHV) during puberty show secular trends during four decades in a large cohort of school children...
  56. pmc Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity--a prospective study of three independent cohorts
    Sofus C Larsen
    Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals, the Capital Region, Nordre Fasanvej 57, Hovedvejen, entrance 5, Ground Floor, 2000, Frederiksberg Copenhagen, Denmark
    Nutr J 13:43. 2014
    ....
  57. pmc Childhood height and body mass index were associated with risk of adult thyroid cancer in a large cohort study
    Cari M Kitahara
    Authors Affiliations Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland Institute of Preventive Medicine Bispebjerg and Frederiksberg Hospitals, the Capital Region, Copenhagen and Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
    Cancer Res 74:235-42. 2014
    ....
  58. ncbi Alcohol intake, type of beverage, and risk of breast cancer in pre- and postmenopausal women
    Anette Lykke Petri
    Copenhagen Centre for Prospective Population Studies, Danish Epidemiology Science Centre at the Institute of Preventive Medicine, H S Kommunehospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Alcohol Clin Exp Res 28:1084-90. 2004
    ..Most studies of the relation between alcohol consumption and breast cancer have shown a modestly increased risk, although the results are still conflicting...
  59. ncbi Effects of intended weight loss on morbidity and mortality: possible explanations of controversial results
    Tina Berentzen
    Institute for Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    Nutr Rev 64:502-7. 2006
    ..The effects of weight loss on mortality may be a balance between the effects of the loss of harmful abdominal and ectopic fat mass and the loss of beneficial peripheral subcutaneous fat mass and lean body mass...
  60. pmc Being an only or last-born child increases later risk of obesity
    Line K Haugaard
    Institute of Preventive Medicine, Frederiksberg and Bispebjerg University Hospitals, Frederiksberg, Denmark
    PLoS ONE 8:e56357. 2013
    ..However, studies combining these exposures are needed. This study aimed at investigating obesity in children and young adults in regard to different combinations of family size and birth order...
  61. pmc Waist circumference adjusted for body mass index and intra-abdominal fat mass
    Tina Landsvig Berentzen
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 7:e32213. 2012
    ..We studied the prediction of abdominal subcutaneous fat mass (ASFM) and IAFM by WC alone and by addition of BMI as an explanatory factor...
  62. ncbi TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet
    Katrine Grau
    Institute of Preventive Medicine Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    Am J Clin Nutr 91:472-9. 2010
    ..Transcription factor 7-like 2 (TCF7L2) rs7903146 associates with type 2 diabetes and may operate via impaired glucagon-like peptide 1 secretion, which is stimulated more by fat than by carbohydrate ingestion...
  63. pmc Changes in waist circumference and the incidence of diabetes in middle-aged men and women
    Tina Landsvig Berentzen
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 6:e23104. 2011
    ..We investigated the association between DWC and the subsequent risk of diabetes in middle-aged men and women, and evaluated the influence from concurrent changes in body mass index (DBMI)...
  64. doi Prenatal exposures to perfluorinated chemicals and anthropometric measures in infancy
    Camilla Schou Andersen
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Am J Epidemiol 172:1230-7. 2010
    ..After sex stratification, the inverse associations with weight and body mass index were more pronounced in boys, and no clear association was seen for girls...
  65. pmc Morbidity, including fatal morbidity, throughout life in men entering adult life as obese
    Esther Zimmermann
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 6:e18546. 2011
    ..We investigated somatic morbidity, including fatal morbidity, throughout adulthood in men starting adult life as obese...
  66. doi The Copenhagen School Health Records Register
    Jennifer L Baker
    Institute of Preventive Medicine, Copenhagen University Hospital, 1357 Copenhagen K, Denmark
    Scand J Public Health 39:87-90. 2011
    ..The Copenhagen School Health Records Register is an electronic register of health examination information on 372,636 children who attended school in Copenhagen, Denmark from 1936 to 2005...
  67. ncbi Secular trends in childhood obesity in Denmark during 50 years in relation to economic growth
    Jenny Bua
    Institute of Preventive Medicine, Copenhagen University Hospital, Center for Health and Society, Øster Søgade 18 1, DK 1357 Copenhagen, Denmark
    Obesity (Silver Spring) 15:977-85. 2007
    ..Our aim was to examine whether secular trends in childhood overweight and obesity during five decades could be explained by economic growth...
  68. ncbi Heredity of small hard drusen in twins aged 20-46 years
    Inger Christine Munch
    Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark
    Invest Ophthalmol Vis Sci 48:833-8. 2007
    ..To examine the prevalence and heredity of small hard drusen in 220 healthy twins aged 20-46 years...
  69. ncbi Body mass index in childhood and adult risk of primary liver cancer
    Tina Landsvig Berentzen
    Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals, the Capital Region, Copenhagen, Denmark
    J Hepatol 60:325-30. 2014
    ..We investigated if childhood body size during school ages was associated with the risk of primary liver cancer in adults...
  70. pmc Genome-wide association study identifies four loci associated with eruption of permanent teeth
    Frank Geller
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
    PLoS Genet 7:e1002275. 2011
    ..5 (95% confidence interval: 2.9-4.1) fewer permanent teeth than children with 0 or 1 of these alleles...
  71. pmc Birth weight in relation to leisure time physical activity in adolescence and adulthood: meta-analysis of results from 13 nordic cohorts
    Lise Geisler Andersen
    Institute of Preventive Medicine, Center for Health and Society, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 4:e8192. 2009
    ....
  72. doi The Danish Adoption Register
    Liselotte Petersen
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, DK 1357 Copenhagen K, Denmark
    Scand J Public Health 39:83-6. 2011
    ..The Danish Adoption Register was established in 1963-1964 to explore the genetic and environmental contribution to familial aggregation of schizophrenia...
  73. pmc Increased genetic variance of BMI with a higher prevalence of obesity
    Benjamin Rokholm
    Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    PLoS ONE 6:e20816. 2011
    ..We tested the hypothesis that a higher prevalence of obesity and overweight and a higher BMI mean is associated with a larger genetic variation in BMI...
  74. ncbi Intake of macronutrients as predictors of 5-y changes in waist circumference
    Jytte Halkjaer
    Danish Epidemiology Science Centre, Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Am J Clin Nutr 84:789-97. 2006
    ..The diet may influence the development of abdominal obesity, but the few studies that have prospectively examined the relations between diet and changes in waist circumference (WC) have given inconsistent results...
  75. ncbi Growth patterns and the risk of breast cancer in women
    Martin Ahlgren
    Department of Epidemiology Research, Danish Epidemiology Science Center, Statens Serum Institut, Copenhagen, Denmark
    N Engl J Med 351:1619-26. 2004
    ..Adult height and body-mass index influence the risk of breast cancer in women. Whether these associations reflect growth patterns of the fetus or growth during childhood and adolescence is unknown...
  76. ncbi Birth weight and systolic blood pressure in adolescence and adulthood: meta-regression analysis of sex- and age-specific results from 20 Nordic studies
    Michael Gamborg
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Am J Epidemiol 166:634-45. 2007
    ..This meta-analysis supports the evidence of an inverse birth weight-SBP association, regardless of adjustment for concurrent body size. It also reveals important heterogeneity in the shape and strength of the association by sex and age...
  77. pmc Life course path analysis of birth weight, childhood growth, and adult systolic blood pressure
    Michael Gamborg
    Institute of Preventive Medicine, Copenhagen University Hospital and Center for Health and Society, University of Copenhagen, Copenhagen K, Denmark
    Am J Epidemiol 169:1167-78. 2009
    ..These results suggest that increases in body size prior to age 11 years are less harmful to adult blood pressure than increases occurring after this age...
  78. ncbi High prepregnant body mass index is associated with early termination of full and any breastfeeding in Danish women
    Jennifer L Baker
    Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
    Am J Clin Nutr 86:404-11. 2007
    ..An association between high prepregnant body mass index (BMI) and early termination of breastfeeding has been observed, but this finding may have depended on the sociocultural context...
  79. ncbi [The cost of obesity on the Danish health care system]
    Ann Louise Worre-Jensen
    Københavns Universitetshospital, Institut for Sygdomsforebyggelse, København K
    Ugeskr Laeger 169:2634-7. 2007
    ..Quantitative measures of the economic costs related to obesity constitute a necessary basis for the organization of treatments, health promotion and for health policies...
  80. pmc Childhood body-mass index and the risk of coronary heart disease in adulthood
    Jennifer L Baker
    Institute of Preventive Medicine, Center for Health and Society, Copenhagen, Denmark
    N Engl J Med 357:2329-37. 2007
    ..Risk factors for coronary heart disease (CHD) are already identifiable in overweight children. The severity of the long-term effects of excess childhood weight on CHD, however, remains unknown...
  81. pmc Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes
    Sofia I I Kring
    Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    PLoS ONE 4:e6696. 2009
    ..We investigated the associations of single nucleotide polymorphisms (SNPs) of these genes with obesity and metabolic traits...
  82. pmc Genetic and environmental influences on risk of death due to infections assessed in Danish twins, 1943-2001
    Niels Obel
    Department of Infectious Diseases, Rigshospitalet, Copenhagen University, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Am J Epidemiol 171:1007-13. 2010
    ..The concordance rates were generally low, and, although a genetic influence on the risk of death from infectious diseases could be demonstrated, the absolute effect of the genetic component on mortality was small...
  83. doi Genetic and environmental effects on mortality before age 70 years
    Liselotte Petersen
    Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    Epidemiology 19:472-6. 2008
    ..Adoption studies, which rest on different assumptions, may also be used to estimate separately the genetic and environmental effects on rate of dying...
  84. pmc The influence of early exposure to vitamin D for development of diseases later in life
    Ramune Jacobsen
    Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals a part of Copenhagen University Hospital, Nordre Fasanvej 57, DK 2000 Frederiksberg, Denmark
    BMC Public Health 13:515. 2013
    ..The present study includes an in-depth examination of the influence of exposure to vitamin D early in life for development of fractures of the wrist, arm and clavicle; obesity, and type 1 diabetes (T1D) during child- and adulthood...
  85. doi C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients
    Esther Zimmermann
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    J Hepatol 55:660-5. 2011
    ..We aimed to investigate whether associations between various features of NAFLD and hs-CRP are independent of body mass index (BMI) in its broad range among obese patients...
  86. ncbi Breastfeeding reduces postpartum weight retention
    Jennifer L Baker
    Centre for Health and Society, Institute of Preventive Medicine, Copenhagen, Denmark
    Am J Clin Nutr 88:1543-51. 2008
    ..Weight gained during pregnancy and not lost postpartum may contribute to obesity in women of childbearing age...
  87. doi Economic costs of abdominal obesity
    Betina Højgaard
    Danish Institute for Health Services Research, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark
    Obes Facts 1:146-54. 2008
    ..To examine the relationship between waist circumference and future health care costs across a broad range of waist circumference values based on individual level data...
  88. pmc Maternal postpartum distress and childhood overweight
    Teresa A Ajslev
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 5:e11136. 2010
    ..We investigated associations between maternal postpartum distress covering anxiety, depression and stress and childhood overweight...
  89. pmc Age at puberty and the emerging obesity epidemic
    Lise Aksglaede
    Department of Growth and Reproduction, University of Copenhagen, Copenhagen, Denmark
    PLoS ONE 4:e8450. 2009
    ....
  90. ncbi Influence of lifestyle aspects on the association of body size and shape with all-cause mortality in middle-aged men and women
    Janne Bigaard
    Institute of Cancer Epidemiology, The Danish Cancer Society, Copenhagen, Denmark
    Obes Facts 3:252-60. 2010
    ..Waist circumference, BMI and hip circumference are differentially associated with mortality. We investigated the potential influence of selected lifestyle aspects such as smoking, alcohol intake, sports activity and education...
  91. ncbi Energy adjustment methods applied to alcohol analyses
    Ditte Johansen
    Danish Epidemiology Science Centre at the Institute of Preventive Medicine, DK 1399 Copenhagen University Hospital, Copenhagen, Denmark
    Alcohol 31:11-7. 2003
    ..For most diseases, the effect of ethanol predominates over that of substances in the beverage type, which makes the density method less relevant in alcohol analyses...
  92. pmc Maternal Recreational Exercise during Pregnancy in relation to Children's BMI at 7 Years of Age
    Camilla Schou Andersen
    Institute of Preventive Medicine, Copenhagen University Hospital, Øster Søgade 18, 1, 1357 Copenhagen K, Denmark
    Int J Pediatr 2012:920583. 2012
    ..Additionally, we did not find exercise intensity or changes in exercise habits in pregnancy related to the children's BMI or risk of overweight...
  93. pmc Excess mortality rate during adulthood among Danish adoptees
    Liselotte Petersen
    Institute of Preventive Medicine, Copenhagen University Hospital, and Institute of Public Health and Center for Healthy Aging, University of Copenhagen, Department of Biostatistics, Copenhagen, Denmark
    PLoS ONE 5:e14365. 2010
    ..The aim was to investigate whether the cohort of domestic adoptees used for these studies in Denmark is similar to the general population with respect to all-cause mortality and cause-specific mortality rates...
  94. ncbi Birth weight and risk of cancer
    Martin Ahlgren
    Department of Epidemiology Research, Statens Serum Institute, Copenhagen, Denmark
    Cancer 110:412-9. 2007
    ..High birth weight has been associated with risk of breast cancer, whereas studies of other specific cancers and all cancers together have been less conclusive...
  95. pmc Waist circumference and body mass index as predictors of health care costs
    Betina Højgaard
    Danish Institute for Health Services Research, Copenhagen, Denmark
    PLoS ONE 3:e2619. 2008
    ..We furthermore assessed whether a combination of the two measures predicts health care costs better than either individual measure...
  96. pmc Clarithromycin for 2 weeks for stable coronary heart disease: 6-year follow-up of the CLARICOR randomized trial and updated meta-analysis of antibiotics for coronary heart disease
    Christian Gluud
    The Copenhagen Trial Unit, Center for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Cardiology 111:280-7. 2008
    ..Here we report the 6-year mortality of clarithromycin- versus placebo-exposed patients and updated meta-analyses...
  97. pmc Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes
    Camilla H Andreasen
    Steno Diabetes Center, Copenhagen, Denmark
    PLoS ONE 3:e2872. 2008
    ..We focused on physical activity as an environmental risk factor, and on the GWA identified obesity variants in FTO (rs9939609) and near MC4R (rs17782313) as genetic risk factors...
  98. ncbi Changes in alcohol intake and mortality: a longitudinal population-based study
    Morten Grønbaek
    Copenhagen Centre for Prospective Population Studies, Danish Epidemiology Science Centre, H S Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Epidemiology 15:222-8. 2004
    ..We studied whether changes in individual alcohol intake result in corresponding changes in mortality...
  99. ncbi Overall and cause-specific mortality in ulcerative colitis: meta-analysis of population-based inception cohort studies
    Tine Jess
    Department of Medical Gastroenterology C, Herlev University Hospital, Copenhagen, Denmark
    Am J Gastroenterol 102:609-17. 2007
    ..We aimed to clarify this issue by conducting a meta-analysis of population-based inception cohort studies on overall and cause-specific mortality in patients with UC...
  100. ncbi The journal impact factor as a predictor of trial quality and outcomes: cohort study of hepatobiliary randomized clinical trials
    Lise L Gluud
    The Cochrane Hepato Biliary Group, The Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark
    Am J Gastroenterol 100:2431-5. 2005
    ..To examine the association between the impact factor and characteristics of hepatobiliary randomized clinical trials...
  101. ncbi Lower risk for alcohol-induced cirrhosis in wine drinkers
    Ulrik Becker
    Copenhagen Centre for Prospective Population Studies, Danish Epidemiology Science Centre at the Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Hepatology 35:868-75. 2002
    ..2-0.5) for developing cirrhosis. In conclusion, the results suggest that a high intake of all 3 types of alcohol conveys an increased risk for cirrhosis, but wine drinkers are at a lower risk than beer and spirits drinkers...