Affiliation: Copenhagen University Hospital
- Doubling of the tuberculosis incidence in Greenland over an 8-year period (1990-1997)C Søborg
Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
Int J Tuberc Lung Dis 5:257-65. 2001..To determine the trends in conventional and molecular epidemiology of tuberculosis (TB) in Greenland over an 8-year period...
- Natural resistance-associated macrophage protein 1 polymorphisms are associated with microscopy-positive tuberculosisChristian Søborg
Department of Clinical Immunology, Tissue Typing Laboratory, Rigshospitalet, Denmark
J Infect Dis 186:517-21. 2002..These results indicate that variant alleles in the Nramp1 gene are associated with increased mycobacterial replication rather than susceptibility for tuberculosis and may thus confer increased risk of severe disease...
- Mannose-binding lectin polymorphisms in clinical tuberculosisChristian Søborg
Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark
J Infect Dis 188:777-82. 2003..The same tendency also was observed in patients of other ethnic origin. It may be hypothesized that heterozygosity for MBL variant alleles, which encodes low serum MBL levels, is associated with protection against clinical tuberculosis...
- Influence of candidate susceptibility genes on tuberculosis in a high endemic regionChristian Søborg
Tissue Typing Laboratory of the Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark
Mol Immunol 44:2213-20. 2007..The observed association was seen only in HIV negative patients suggesting that this genetic susceptibility for tuberculosis may be surpassed by co-infections...