Anne Sabers

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. doi A prospective, randomized, multicentre trial for the treatment of refractory status epilepticus; experiences from evaluating the effect of the novel drug candidate, NS1209
    Anne Sabers
    The Epilepsy Clinic, Department of Neurology, University State Hospital, Rigshospitalet, Copenhagen, Denmark
    Epilepsy Res 106:292-5. 2013
  2. doi Algorithm for lamotrigine dose adjustment before, during, and after pregnancy
    A Sabers
    The Epilepsy Clinic, Department of Neurology, University State Hospital, Rigshospitalet, Copenhagen, Denmark
    Acta Neurol Scand 126:e1-4. 2012
  3. doi No effect of oral contraceptives on the metabolism of levetiracetam
    Anne Sabers
    The Epilepsy Clinic, Department of Neurology, Rigshospitalet University State Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Epilepsy Res 95:277-9. 2011
  4. doi Seizure frequency in pregnant women treated with lamotrigine monotherapy
    Anne Sabers
    The Epilepsy Clinic, Glostrup University Hospital, Glostrup, Denmark
    Epilepsia 50:2163-6. 2009
  5. doi Seizure deterioration in women treated with oxcarbazepine during pregnancy
    Vaiva Petrenaite
    The Epilepsy Clinic, Department of Neurology, Glostrup University Hospital, DK 2600 Glostrup, Denmark
    Epilepsy Res 84:245-9. 2009
  6. ncbi Oral contraceptives induce lamotrigine metabolism: evidence from a double-blind, placebo-controlled trial
    Jakob Christensen
    Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
    Epilepsia 48:484-9. 2007
  7. ncbi [Valproate treatment during pregnancy: description of four cases with foetal valproate syndrome]
    Anne Sabers
    Epilepsiklinikken, Glostrup Hospital, DK 2600 Glostrup
    Ugeskr Laeger 171:221-5. 2009
  8. doi Influences on seizure activity in pregnant women with epilepsy
    Anne Sabers
    The Epilepsy Clinic, Glostrup University Hospital, Ndr Ringvej, Glostrup DK 2600, Denmark
    Epilepsy Behav 15:230-4. 2009
  9. doi Managing antiepileptic drugs during pregnancy and lactation
    Anne Sabers
    The Epilepsy Clinic, Glostrup University Hospital, Glostrup, Denmark
    Curr Opin Neurol 22:157-61. 2009
  10. doi Epilepsy and risk of death and sudden unexpected death in the young: a nationwide study
    Anders Gaarsdal Holst
    The Danish National Research Foundation Center for Cardiac Arrhythmia DARC, Copenhagen, Denmark
    Epilepsia 54:1613-20. 2013

Detail Information

Publications15

  1. doi A prospective, randomized, multicentre trial for the treatment of refractory status epilepticus; experiences from evaluating the effect of the novel drug candidate, NS1209
    Anne Sabers
    The Epilepsy Clinic, Department of Neurology, University State Hospital, Rigshospitalet, Copenhagen, Denmark
    Epilepsy Res 106:292-5. 2013
    ..We conclude that high-quality studies in RSE are difficult to conduct owing to a number of ethical and practical problems associated with this critical illness. Challenges for further studies are discussed...
  2. doi Algorithm for lamotrigine dose adjustment before, during, and after pregnancy
    A Sabers
    The Epilepsy Clinic, Department of Neurology, University State Hospital, Rigshospitalet, Copenhagen, Denmark
    Acta Neurol Scand 126:e1-4. 2012
    ..The extent to which pregnancy affects LTG pharmacokinetics is unpredictable and varies considerably among patients...
  3. doi No effect of oral contraceptives on the metabolism of levetiracetam
    Anne Sabers
    The Epilepsy Clinic, Department of Neurology, Rigshospitalet University State Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Epilepsy Res 95:277-9. 2011
    ..8). In conclusion, combing LEV and OCs seems safe from a pharmacokinetic perspective...
  4. doi Seizure frequency in pregnant women treated with lamotrigine monotherapy
    Anne Sabers
    The Epilepsy Clinic, Glostrup University Hospital, Glostrup, Denmark
    Epilepsia 50:2163-6. 2009
    ..It was demonstrated that with this close monitoring set-up, the risk of increased seizure frequency (19%) was not higher than that reported for other AED treatment regimens...
  5. doi Seizure deterioration in women treated with oxcarbazepine during pregnancy
    Vaiva Petrenaite
    The Epilepsy Clinic, Department of Neurology, Glostrup University Hospital, DK 2600 Glostrup, Denmark
    Epilepsy Res 84:245-9. 2009
    ..There was a trend toward a correlation between seizure deterioration and decrease in plasma concentration of MHD...
  6. ncbi Oral contraceptives induce lamotrigine metabolism: evidence from a double-blind, placebo-controlled trial
    Jakob Christensen
    Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
    Epilepsia 48:484-9. 2007
    ..This study evaluates the effect of oral contraceptives on lamotrigine (LTG) plasma concentrations and urine excretion of LTG metabolites in a double-blind, placebo-controlled, crossover study in patients with epilepsy...
  7. ncbi [Valproate treatment during pregnancy: description of four cases with foetal valproate syndrome]
    Anne Sabers
    Epilepsiklinikken, Glostrup Hospital, DK 2600 Glostrup
    Ugeskr Laeger 171:221-5. 2009
    ..This paper aims to give attention to the syndrome through four case descriptions. Furthermore, possible risk factors and the use of the mutation 677C-T as a risk marker are discussed...
  8. doi Influences on seizure activity in pregnant women with epilepsy
    Anne Sabers
    The Epilepsy Clinic, Glostrup University Hospital, Ndr Ringvej, Glostrup DK 2600, Denmark
    Epilepsy Behav 15:230-4. 2009
    ..001). With some methodological limitations taken into account, it is concluded that women followed in a specialized epilepsy clinic have a lower risk of seizure deterioration during pregnancy compared with those referred after conception...
  9. doi Managing antiepileptic drugs during pregnancy and lactation
    Anne Sabers
    The Epilepsy Clinic, Glostrup University Hospital, Glostrup, Denmark
    Curr Opin Neurol 22:157-61. 2009
    ..This review discusses data on the pharmacokinetics of antiepileptic drugs (AEDs) in pregnancy and lactation, and the clinical consequences thereof, thus providing a basis for a rational management of AEDs during pregnancy and lactation...
  10. doi Epilepsy and risk of death and sudden unexpected death in the young: a nationwide study
    Anders Gaarsdal Holst
    The Danish National Research Foundation Center for Cardiac Arrhythmia DARC, Copenhagen, Denmark
    Epilepsia 54:1613-20. 2013
    ..We aimed to chart the incidence of sudden unexpected death in epilepsy (SUDEP) and estimate the risk of death from all causes and SUD conferred by epilepsy independently...
  11. ncbi Individual changes in lamotrigine plasma concentrations during pregnancy
    Vaiva Petrenaite
    Department of Clinical Neurophysiology 3063, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Epilepsy Res 65:185-8. 2005
    ..The pharmacokinetic changes display marked inter-patient variation, which stresses the importance of evaluating each woman individually by closely monitoring LTG concentrations until term...
  12. doi Pharmacokinetic interactions between contraceptives and antiepileptic drugs
    Anne Sabers
    The Epilepsy Clinic, Department of Neurology, Glostrup University Hospital, Denmark
    Seizure 17:141-4. 2008
    ..It is therefore recommended that change in OC use is assisted by AED monitoring whenever possible...
  13. doi Pharmacokinetics of antiepileptic drugs in pregnancy
    Anne Sabers
    Glostrup University Hospital, The Epilepsy Clinic, Department of Neurology, DK 2600 Glostrup, Denmark
    Expert Rev Clin Pharmacol 1:129-36. 2008
    ....
  14. ncbi Promising effect of vagal stimulation in Danish patients with epilepsy
    Kristin Sjølie Thygesen
    Department of Neurology, Rigshospitalet, 2100 Copenhagen, Denmark
    Dan Med J 60:A4597. 2013
    ..The aims of this study were to evaluate the effect of VNS on seizure frequency and to investigate patient satisfaction of and quality of life effects of VNS treatment...
  15. ncbi Source analysis of epileptic discharges using multiple signal classification analysis
    Sandor Beniczky
    Department of Clinical Neurophysiology, Department of Neurology, Copenhagen University, Glostrup Hospital, Glostrup, Denmark
    Neuroreport 17:1283-7. 2006
    ..Multiple signal classification analysis is a promising tool in localizing foci in patients with complex partial seizures and may contribute to the preoperative evaluation...