Henrik Kehlet

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. doi request reprint Postoperative ileus--an update on preventive techniques
    Henrik Kehlet
    Copenhagen University, Rigshospitalet, Copenhagen University, Denmark
    Nat Clin Pract Gastroenterol Hepatol 5:552-8. 2008
  2. doi request reprint Length of stay after laparoscopic colonic surgery - an 11-year nationwide Danish survey
    H Kehlet
    Section for Surgical Pathophysiology, Rigshospitalet Copenhagen University, Copenhagen, Denmark
    Colorectal Dis 14:1118-20. 2012
  3. pmc Patient-reported outcome after fast-track hip arthroplasty: a prospective cohort study
    Kristian Larsen
    Orthopaedic Research Unit, Department of Orthopedics, Holstebro Regional Hospital, Hospital Unit West, Denmark
    Health Qual Life Outcomes 8:144. 2010
  4. ncbi request reprint [Chronic pain after groin hernia repair]
    Henrik Kehlet
    Enhed for Kirurgisk Patofysiologi, Rigshospitalet, 2100 København Ø, Denmark
    Ugeskr Laeger 173:45-7. 2011
  5. doi request reprint Multimodal approach to postoperative recovery
    Henrik Kehlet
    Section of Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Blegdamsvej 9, Copenhagen 2100, Denmark
    Curr Opin Crit Care 15:355-8. 2009
  6. doi request reprint Local anaesthesia as a risk factor for recurrence after groin hernia repair
    H Kehlet
    Section of Surgical Pathophysiology, Copenhagen University Hospital Rigshospitalet, 4074, Copenhagen, Denmark
    Hernia 12:507-9. 2008
  7. doi request reprint Fast-track surgery-an update on physiological care principles to enhance recovery
    Henrik Kehlet
    Section for Surgical Pathophysiology, Rigshospitalet Copenhagen University, Blegdamsvej 9, 2100, Copenhagen, Denmark
    Langenbecks Arch Surg 396:585-90. 2011
  8. doi request reprint Chronic pain after groin hernia repair
    H Kehlet
    Section of Surgical Pathophysiology 4074, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Br J Surg 95:135-6. 2008
  9. doi request reprint Risk of morbidity, mortality, and recurrence after parastomal hernia repair: a nationwide study
    Frederik Helgstrand
    1 The Danish Hernia Database, Copenhagen, Denmark 2 Department of Surgery, Køge Hospital, University of Copenhagen, Køge, Denmark 3 Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark 4 Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark 5 Department of Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark 6 Department of Surgery, Colorectal Division, Aarhus University Hospital, Aarhus, Denmark 7 Department of Surgery, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark
    Dis Colon Rectum 56:1265-72. 2013
  10. doi request reprint Persistent pain, sensory disturbances and functional impairment after adjuvant chemotherapy for breast cancer: cyclophosphamide, epirubicin and fluorouracil compared with docetaxel + epirubicin and cyclophosphamide
    Kenneth Geving Andersen
    Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    Acta Oncol 51:1036-44. 2012

Detail Information

Publications199 found, 100 shown here

  1. doi request reprint Postoperative ileus--an update on preventive techniques
    Henrik Kehlet
    Copenhagen University, Rigshospitalet, Copenhagen University, Denmark
    Nat Clin Pract Gastroenterol Hepatol 5:552-8. 2008
    ..There is a need for data on the effect of these techniques on POI when applied to major upper abdominal surgeries and emergency abdominal operations (e.g. trauma, peritonitis, etc.)...
  2. doi request reprint Length of stay after laparoscopic colonic surgery - an 11-year nationwide Danish survey
    H Kehlet
    Section for Surgical Pathophysiology, Rigshospitalet Copenhagen University, Copenhagen, Denmark
    Colorectal Dis 14:1118-20. 2012
    ..The use of laparoscopic colonic surgery in Denmark was analysed with particular reference to the length of stay...
  3. pmc Patient-reported outcome after fast-track hip arthroplasty: a prospective cohort study
    Kristian Larsen
    Orthopaedic Research Unit, Department of Orthopedics, Holstebro Regional Hospital, Hospital Unit West, Denmark
    Health Qual Life Outcomes 8:144. 2010
    ..The purpose of this study was to describe patient-related outcomes, the need for additional rehabilitation after a fast-track total hip arthroplasty (THA), and the association between generic and disease specific outcomes...
  4. ncbi request reprint [Chronic pain after groin hernia repair]
    Henrik Kehlet
    Enhed for Kirurgisk Patofysiologi, Rigshospitalet, 2100 København Ø, Denmark
    Ugeskr Laeger 173:45-7. 2011
    ..The choice between pharmacological intervention and re-exploration is debatable. A centralisation of the Danish patients with regard to evaluation and treatment is proposed...
  5. doi request reprint Multimodal approach to postoperative recovery
    Henrik Kehlet
    Section of Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Blegdamsvej 9, Copenhagen 2100, Denmark
    Curr Opin Crit Care 15:355-8. 2009
    ..To provide updated information on recent developments within individual components of multimodal interventions to improve postoperative outcome (fast-track methodology)...
  6. doi request reprint Local anaesthesia as a risk factor for recurrence after groin hernia repair
    H Kehlet
    Section of Surgical Pathophysiology, Copenhagen University Hospital Rigshospitalet, 4074, Copenhagen, Denmark
    Hernia 12:507-9. 2008
    ..The literature is inconclusive regarding the effect of local infiltration anaesthesia on the risk of recurrence after groin hernia repair...
  7. doi request reprint Fast-track surgery-an update on physiological care principles to enhance recovery
    Henrik Kehlet
    Section for Surgical Pathophysiology, Rigshospitalet Copenhagen University, Blegdamsvej 9, 2100, Copenhagen, Denmark
    Langenbecks Arch Surg 396:585-90. 2011
    ..The concept of fast-track surgery (enhanced recovery programs) has been evolved and been documented to be successful by decreasing length of stay, morbidity and convalescence across procedures...
  8. doi request reprint Chronic pain after groin hernia repair
    H Kehlet
    Section of Surgical Pathophysiology 4074, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Br J Surg 95:135-6. 2008
  9. doi request reprint Risk of morbidity, mortality, and recurrence after parastomal hernia repair: a nationwide study
    Frederik Helgstrand
    1 The Danish Hernia Database, Copenhagen, Denmark 2 Department of Surgery, Køge Hospital, University of Copenhagen, Køge, Denmark 3 Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark 4 Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark 5 Department of Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark 6 Department of Surgery, Colorectal Division, Aarhus University Hospital, Aarhus, Denmark 7 Department of Surgery, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark
    Dis Colon Rectum 56:1265-72. 2013
    ..Surgical outcome results after repair for parastomal hernia are sparsely reported and based on small-scale studies...
  10. doi request reprint Persistent pain, sensory disturbances and functional impairment after adjuvant chemotherapy for breast cancer: cyclophosphamide, epirubicin and fluorouracil compared with docetaxel + epirubicin and cyclophosphamide
    Kenneth Geving Andersen
    Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    Acta Oncol 51:1036-44. 2012
    ....
  11. ncbi request reprint [Perioperative care of patients with stage IIIC ovarian cancer]
    Dorthe Hjort Jakobsen
    Enhed for Perioperativ Sygepleje Afsnit 3341 Rigshospitalet, Gynakologisk Klinik, Blegdamsvej 9, 2100 København Ø, Denmark
    Ugeskr Laeger 172:2688-91. 2010
    ..The purpose of this study was to assess and discuss perioperative care principles in patients undergoing ovarian cancer surgery with stage IIIC at the six centres in Denmark performing this surgical procedure...
  12. doi request reprint Evidence-based surgical care and the evolution of fast-track surgery
    Henrik Kehlet
    Section of Surgical Pathophysiology 4074, Rigshospitalet, Copenhagen, Denmark
    Ann Surg 248:189-98. 2008
    ..Optimization of postoperative outcome requires the application of evidence-based principles of care carefully integrated into a multimodal rehabilitation program...
  13. doi request reprint Predictive risk factors for persistent postherniotomy pain
    Eske K Aasvang
    Section of Surgical Pathophysiology, The Juliane Marie Centre, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    Anesthesiology 112:957-69. 2010
    ..Persistent postherniotomy pain (PPP) affects everyday activities in 5-10% of patients. Identification of predisposing factors may help to identify the risk groups and guide anesthetic or surgical procedures in reducing risk for PPP...
  14. doi request reprint Acute hospitalization of the older patient: changes in muscle strength and functional performance during hospitalization and 30 days after discharge
    Ann Christine Bodilsen
    Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark
    Am J Phys Med Rehabil 92:789-96. 2013
    ..The aim of this study was to investigate the effect of acute hospitalization as a result of medical disease on muscle strength and functional performance in older medical patients...
  15. doi request reprint Nationwide prospective study of outcomes after elective incisional hernia repair
    Frederik Helgstrand
    The Danish Ventral Hernia Database, Copenhagen, Denmark
    J Am Coll Surg 216:217-28. 2013
    ..The aim of this nationwide study was to analyze surgical risk factors for early and late outcomes after incisional hernia repair...
  16. pmc Why still in hospital after fast-track hip and knee arthroplasty?
    Henrik Husted
    Department of Orthopaedic Surgery, Hvidovre University Hospital, Copenhagen, Denmark
    Acta Orthop 82:679-84. 2011
    ..Earlier studies have identified patient characteristics predicting LOS, but little is known about specific reasons for being hospitalized following fast-track THA and TKA...
  17. doi request reprint Heterogeneous sensory processing in persistent postherniotomy pain
    Eske Kvanner Aasvang
    Section of Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Denmark
    Pain 150:237-42. 2010
    ..Z-score evaluation of sensory function identifies subpopulations in PPP, which may be used in selecting surgical and/or pharmacological treatment strategies...
  18. doi request reprint Can preoperative electrical nociceptive stimulation predict acute pain after groin herniotomy?
    Eske Kvanner Aasvang
    Section of Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark
    J Pain 9:940-4. 2008
    ..Preoperative electrical pain detection threshold and electrical pain tolerance threshold did not correlate to postoperative pain (rho = -0.13, P = .09, and rho = -1.2, P = .4, respectively...
  19. doi request reprint Readmissions after fast-track hip and knee arthroplasty
    Henrik Husted
    Department of Orthopedic Surgery, Hvidovre University Hospital, Copenhagen, Denmark
    Arch Orthop Trauma Surg 130:1185-91. 2010
    ..However, it has been speculated that a decrease in LOS may be associated with an increase in readmissions in general, including risk of dislocation after total hip arthroplasty (THA) or manipulation after total knee arthroplasty (TKA)...
  20. doi request reprint Self-reported arm-lymphedema and functional impairment after breast cancer treatment--a nationwide study of prevalence and associated factors
    Rune Gärtner
    Department of Breast Surgery, Rigshospitalet 3103, Copenhagen University, 2100 Copenhagen, Denmark
    Breast 19:506-15. 2010
    ..Giving up activities was associated with pain and swelling/heaviness, younger age, ALND, chemotherapy, time elapsed since surgery, and surgery on the dominant side. Radiotherapy and type of breast surgery were of no importance...
  21. doi request reprint Chronic pain after lung transplantation: a nationwide study
    Kim Wildgaard
    Department of Cardiothoracic Anesthesia double daggerDivision of Lung Transplantation, Heart Center Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Denmark
    Clin J Pain 26:217-22. 2010
    ..Therefore, we investigated the nationwide incidence of chronic pain after lung transplantations...
  22. ncbi request reprint Does neoadjuvant chemotherapy impair long-term survival for ovarian cancer patients? A nationwide Danish study
    Carsten Lindberg Fagö-Olsen
    Department of Gynecology and Obstetrics, Rigshospitalet, Copenhagen University Hospital, Denmark Electronic address
    Gynecol Oncol 132:292-8. 2014
    ..We aimed to evaluate the impact of first-line treatment on surgical outcome and median overall survival (MOS)...
  23. doi request reprint Does goal-directed fluid therapy affect postoperative orthostatic intolerance?: A randomized trial
    Morten Bundgaard-Nielsen
    Research Fellow, Research Assistant, Section of Surgical Pathophysiology, The Juliane Marie Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, and Department of Anesthesiology, The Abdominal Center, Copenhagen University Hospital, Rigshospitalet Research Fellow, Professor, Section of Surgical Pathophysiology, The Juliane Marie Center, Copenhagen University Hospital, Rigshospitalet Staff Anesthesiologist, Head of Department, Professor, Department of Anesthesiology, The Abdominal Center, Copenhagen University Hospital, Rigshospitalet Professor, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark
    Anesthesiology 119:813-23. 2013
    ....
  24. doi request reprint Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter
    Kim Wildgaard
    Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    Eur J Cardiothorac Surg 41:1072-7. 2012
    ..A simple multimodal approach using an intercostal catheter (ICC) may be of benefit since acute post-operative pain following VATS lobectomy primarily originates from the chest drain area...
  25. doi request reprint Pre-operative pain and sensory function in groin hernia
    Eske K Aasvang
    Section of Surgical Pathophysiology, 4074 Rigshospitalet, Blegdamsvej 9, Copenhagen University, 2100 Copenhagen Ø, Denmark
    Eur J Pain 13:1018-22. 2009
    ..Since pre-operative pain has been demonstrated to be a risk factor for persistent postherniotomy pain, pre-operative alterations in nociceptive function may be a potential pathogenic mechanism...
  26. ncbi request reprint Cognitive dysfunction after fast-track hip and knee replacement
    Lene Krenk
    From the Section of Surgical Pathophysiology and Department of Anesthesia, Centre of Head and Orthopedics, Rigshospitalet, University of Copenhagen The Lundbeck Centre for Fast Track Hip and Knee Arthroplasty, Copenhagen Department of Orthopaedic Surgery, Holstebro Hospital, Holstebro Department of Orthopaedic Surgery, Gentofte Hospital, Gentofte Department of Orthopaedic Surgery, Arhus University Hospital, Århus and Department of Anesthesia, Centre of Head and Orthopaedics, University Hospital of Copenhagen, Copenhagen, Denmark
    Anesth Analg 118:1034-40. 2014
    ..Patients were in an optimized perioperative approach (fast track) with multimodal opioid-sparing analgesia, early mobilization, and short length of stay (LOS ≤3 days) and discharged to home...
  27. doi request reprint Outcomes after emergency versus elective ventral hernia repair: a prospective nationwide study
    Frederik Helgstrand
    Danish Ventral Hernia Database, Copenhagen, Denmark
    World J Surg 37:2273-9. 2013
    ..Thus, the aim of present study was to investigate early results and risk factors for poor 30-day outcome after emergency versus elective repair for ventral hernias...
  28. pmc A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery
    Ole Mathiesen
    Section of Acute Pain Management and Palliative Medicine, Department of Anesthesia 4231, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark
    Eur Spine J 22:2089-96. 2013
    ..This case-control study investigated if a standardized comprehensive pain and postoperative nausea and vomiting (PONV) treatment protocol would improve pain treatment in this population...
  29. ncbi request reprint Activity, sleep and cognition after fast-track hip or knee arthroplasty
    Lene Krenk
    Section of Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Denmark
    J Arthroplasty 28:1265-9. 2013
    ..Objective assessment of these recovery parameters may be valuable in future interventional studies to enhance recovery after THA/TKA...
  30. ncbi request reprint Nationwide quality improvement of groin hernia repair from the Danish Hernia Database of 87,840 patients from 1998 to 2005
    H Kehlet
    Section for Surgical Pathophysiology, Juliane Marie Centre, 4074, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark
    Hernia 12:1-7. 2008
    ....
  31. ncbi request reprint Effect of laxatives on gastrointestinal functional recovery in fast-track hysterectomy: a double-blind, placebo-controlled randomized study
    Charlotte T Hansen
    Department of Gynecology and Obstetrics, Hvidovre University Hospital, Copenhagen, Denmark
    Am J Obstet Gynecol 196:311.e1-7. 2007
    ....
  32. doi request reprint Persistent pain and sensory disturbances after treatment for breast cancer: six year nationwide follow-up study
    Mathias Kvist Mejdahl
    Section for Surgical Pathophysiology, 7621 Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    BMJ 346:f1865. 2013
    ..To examine the development of persistent pain after treatment for breast cancer and to examine risk factors associated with continuing pain...
  33. pmc Functional recovery after open versus laparoscopic colonic resection: a randomized, blinded study
    Linda Basse
    Department of Surgical Gastroenterology, Copenhagen University Hospital, Hvidovre, Kettegaard Alle 30, DK 2650 Hvidovre, Denmark
    Ann Surg 241:416-23. 2005
    ..Since no comparative data between laparoscopic and open colonic resection with multimodal rehabilitation are available, the value of laparoscopy per se is unknown...
  34. doi request reprint Psychological distress among women with newly diagnosed breast cancer
    Birgitte Goldschmidt Mertz
    Department of Breast Surgery, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen Ø, Denmark
    Eur J Oncol Nurs 16:439-43. 2012
    ..Our objectives were to determine the prevalence of distress and to investigate the related problems and the characteristics of women with breast cancer who experienced psychological distress at the time of diagnosis...
  35. doi request reprint Ultrasound-guided ilioinguinal/iliohypogastric nerve blocks for persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial
    Joakim M Bischoff
    Section of Surgical Pathophysiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Anesth Analg 114:1323-9. 2012
    ..In this controlled study, we investigated the analgesic and sensory effects of ultrasound-guided blocks of the ilioinguinal and iliohypogastric nerves with lidocaine...
  36. ncbi request reprint Ejaculatory pain: a specific postherniotomy pain syndrome?
    Eske K Aasvang
    Section of Surgical Pathophysiology, The Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark
    Anesthesiology 107:298-304. 2007
    ..5% of patients. However, the specific psychosexological and neurophysiologic characteristics have not been described, thereby precluding assessment of pathogenic mechanisms and treatment strategies...
  37. ncbi request reprint Pain and sensory dysfunction 6 to 12 months after inguinal herniotomy
    Trine Mikkelsen
    Department of Surgical Gastroenterologye, Hvidovre University Hospital, Copenhagen, Denmark
    Anesth Analg 99:146-51. 2004
    ..Factors other than nerve damage may be involved in the development of chronic posthemiotomy pain...
  38. ncbi request reprint Painful tonic heat stimulation induces GABA accumulation in the prefrontal cortex in man
    Ron Kupers
    Department of Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark
    Pain 142:89-93. 2009
    ..The results are in line with animal findings on the role of GABA in pain processing and with studies in humans showing analgesic efficacy of GABA-related drugs in clinical pain conditions...
  39. doi request reprint Sensory testing in patients with postthoracotomy pain syndrome: Part 1: mirror-image sensory dysfunction
    Mads U Werner
    Multidisciplinary Pain Center, Neuroscience Center Rigshospitalet, Copenhagen, Denmark
    Clin J Pain 29:775-83. 2013
    ..Mirror-image sensory dysfunction (MISD) has not been systematically characterized in persistent postoperative pain...
  40. doi request reprint Lidocaine patch (5%) in treatment of persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial
    Joakim M Bischoff
    Research Assistant, Multidisciplinary Pain Centre 7612, Rigshospitalet, Copenhagen University, Copenhagen, Denmark, and Section of Surgical Pathophysiology 4074, Rigshospitalet, Copenhagen University Research Nurse, Associate Professor, Multidisciplinary Pain Centre 7612, Rigshospitalet, Copenhagen University Assistant Professor, Professor, Department of Neurology, University Hospital of Wurzburg, Wurzburg, Germany professor, Section of Surgical Pathophysiology 4074, Rigshospitalet, Copenhagen University
    Anesthesiology 119:1444-52. 2013
    ..Evidence-based pharmacological treatment options for patients with persistent inguinal postherniorrhaphy pain are lacking...
  41. doi request reprint Quantitative sensory testing in patients with postthoracotomy pain syndrome: Part 2: variability in thermal threshold assessments
    Kim Wildgaard
    Section for Surgical Pathophysiology, Copenhagen University Hospital, Copenhagen, Denmark
    Clin J Pain 29:784-90. 2013
    ..The objective of the study was to assess the test-retest variability of thermal thresholds in patients (n = 14) with the postthoracotomy pain syndrome...
  42. doi request reprint Delirium in the fast-track surgery setting
    Lene Krenk
    Rigshospitalet, Section of Surgical Pathophysiology, The Lundbeck Centre for Fast track Hip and Knee Arthroplasty, Copenhagen O, Denmark
    Best Pract Res Clin Anaesthesiol 26:345-53. 2012
    ..In conclusion, the fast-track methodology may reduce the incidence of postoperative cognitive decline after surgery...
  43. ncbi request reprint Centralized treatment of advanced stages of ovarian cancer improves survival: a nationwide Danish survey
    Carsten L Fagö-Olsen
    Department of Gynecology, Juliane Marie Centre, Copenhagen, Denmark
    Acta Obstet Gynecol Scand 90:273-9. 2011
    ..This retrospective, nationwide, observational study was designed to compare treatment in tertiary referral centers vs. regional hospitals on overall survival for patients with stage IIIC and IV ovarian cancer...
  44. ncbi request reprint Need for improved treatment of postoperative pain
    Ole Mathiesen
    Section of Acute Pain Management and Palliative Care 4114, Rigshospitalet, Denmark
    Dan Med J 59:A4401. 2012
    ..A cross-sectional study was performed at Rigshospitalet, Copenhagen, a Danish tertiary university hospital, to describe current postoperative pain and nausea treatment with a view to identifying areas with improvement potential...
  45. doi request reprint Prevalence of and factors associated with persistent pain following breast cancer surgery
    Rune Gärtner
    Department of Breast Surgery, Rigshospitalet 2101, University of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    JAMA 302:1985-92. 2009
    ..The pathogenic mechanisms are complex and may be related to patient characteristics, surgical technique, and adjuvant therapy...
  46. doi request reprint Postoperative recovery profile after elective abdominal hysterectomy: a prospective, observational study of a multimodal anaesthetic regime
    Kenneth Jensen
    Department of Anaesthesiology and Intensive Care, Acute Pain Service 530, Hvidovre University Hospital, Copenhagen, Denmark
    Eur J Anaesthesiol 26:382-8. 2009
    ..To evaluate the applicability, effectiveness, immediate postoperative complaints and requirements for a postanaesthesia care unit stay after elective abdominal hysterectomy under a well defined, multimodal anaesthetic regime...
  47. ncbi request reprint Organisation and quality of primary surgical intervention for ovarian cancer in Denmark
    Charlotte Marx
    Department of Gynecology, Juliane Marie Centre, Rigshospitalet, Blegdamsvej, Copenhagen, Denmark
    Acta Obstet Gynecol Scand 86:1496-502. 2007
    ..The primary aim of the present study was, therefore, to evaluate the organisation and quality of current primary surgical intervention for ovarian cancer in Denmark...
  48. ncbi request reprint Fast-track surgery for breast cancer is possible
    Birgitte G Mertz
    Sektion for Brystkirurgi, Rigshospitalet, 2100 Copenhagen Ø, Denmark
    Dan Med J 60:A4615. 2013
    ..The aim of this study is to describe the new clinical pathway for breast cancer patients after implementation of a fast-track surgery programme...
  49. doi request reprint Pain-related impairment of daily activities after thoracic surgery: a questionnaire validation
    Thomas K Ringsted
    Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark
    Clin J Pain 29:791-9. 2013
    ..Thus, the purpose was to create a procedure-specific questionnaire for assessment of functional impairment due to PTPS...
  50. doi request reprint Intraoperative local infiltration analgesia for early analgesia after total hip arthroplasty: a randomized, double-blind, placebo-controlled trial
    Troels H Lunn
    Department of Anesthesiology, Hvidovre University Hospital, Copenhagen, Denmark
    Reg Anesth Pain Med 36:424-9. 2011
    ..Therefore, we evaluated whether intraoperative high-volume LIA, in addition to a multimodal oral analgesic regimen, would further reduce acute postoperative pain after THA...
  51. doi request reprint Persistent pain after targeted intraoperative radiotherapy (TARGIT) or external breast radiotherapy for breast cancer: a randomized trial
    Kenneth Geving Andersen
    Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Denmark
    Breast 21:46-9. 2012
    ..The response rate was 98%, leaving 238 patients for the final analysis. Pain prevalence were 33.9% in the EBRT group and 24.6% in the IORT group (p = 0.11). Treatment with IORT may not alter the risk of PPBCT...
  52. doi request reprint Neurophysiological characterization of persistent postthoracotomy pain
    Kim Wildgaard
    Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Denmark
    Clin J Pain 28:136-42. 2012
    ....
  53. doi request reprint Fast-track colorectal surgery
    Henrik Kehlet
    Section for Surgical Pathophysiology 4074, Copenhagen University Hospital, Rigshospitalet, 2100 Copenhagen, Denmark
    Lancet 371:791-3. 2008
  54. doi request reprint No evidence for generalized increased postoperative responsiveness to pain: a combined behavioral and serial functional magnetic resonance imaging study
    Ron Kupers
    Department of Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Anesth Analg 109:600-6. 2009
    ..We tested this hypothesis using a postoperative pain model, in conjunction with serial functional magnetic resonance imaging (fMRI)...
  55. ncbi request reprint A compression bandage improves local infiltration analgesia in total knee arthroplasty
    Lasse Ø Andersen
    Departments of Anesthesiology, Hvidovre University Hospital, Copenhagen, Denmark
    Acta Orthop 79:806-11. 2008
    ..High-volume local infiltration analgesia has been shown to be an effective pain treatment after knee replacement, but the role of bandaging to prolong analgesia has not been evaluated...
  56. doi request reprint Re-recurrence after operation for recurrent inguinal hernia. A nationwide 8-year follow-up study on the role of type of repair
    Thue Bisgaard
    The Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark
    Ann Surg 247:707-11. 2008
    ..We analyze, on a nationwide basis, the risk of re-reoperation with reference to previous inguinal hernia repair technique...
  57. doi request reprint MRI and pathology in persistent postherniotomy pain
    Eske Kvanner Aasvang
    Section of Surgical Pathophysiology, Diagnostics Center, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    J Am Coll Surg 208:1023-8; discussion 1028-9. 2009
    ..MRI can potentially be useful in the investigation of pathogenic mechanisms and guide surgeons in mesh removal and neurectomy. No study has investigated interobserver agreement or MRI-specific findings in persistent postherniotomy pain...
  58. ncbi request reprint [Breast cancer surgery in Denmark]
    Niels Kroman
    Rigshospitalet, HovedOrtoCenteret, Brystkirurgisk Afdeling CE, Denmark
    Ugeskr Laeger 172:2836-9. 2010
    ..In order to investigate the organisation of such procedures, the choice of surgical procedures, length of hospitalisation, and mortality were evaluated using information from The National Board of Health...
  59. pmc High-volume infiltration analgesia in bilateral hip arthroplasty. A randomized, double-blind placebo-controlled trial
    Lasse Ø Andersen
    Department of Anesthesiology, Hvidovre Hospital, Copenhagen, Denmark
    Acta Orthop 82:423-6. 2011
    ..High-volume infiltration analgesia may be effective in postoperative pain management after hip arthroplasty but methodological problems prevent exact interpretation of previous studies...
  60. pmc Fast-track revision knee arthroplasty. A feasibility study
    Henrik Husted
    Department of Orthopedic Surgery Hvidovre University Hospital, Copenhagen, Denmark
    Acta Orthop 82:438-40. 2011
    ..We assessed whether patients undergoing revision TKA for non-septic indications might also benefit from fast-track surgery...
  61. doi request reprint A positron emission tomography study of wind-up pain in chronic postherniotomy pain
    Ron Kupers
    Dept of Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    Eur J Pain 15:698.e1-16. 2011
    ..Since no de novo brain areas were activated by wind-up pain, our data suggest that the processes specific to wind-up pain do not occur at the cerebral level...
  62. ncbi request reprint Phantom breast sensations are frequent after mastectomy
    Dorthe Marie Helbo Hansen
    Department of Breast Surgery, Centre of Head and Orthopaedics, Rigshospitalet, Denmark
    Dan Med Bull 58:A4259. 2011
    ..The reported prevalence and risk factors have not been established in large well-defined patient series. The purpose of this study was to examine the prevalence of PBS following mastectomy and associated risk factors...
  63. doi request reprint Late sensory function after intraoperative capsaicin wound instillation
    E K Aasvang
    Section of Surgical Pathophysiology, Copenhagen University, Rigshospitalet, Copenhagen, Denmark
    Acta Anaesthesiol Scand 54:224-31. 2010
    ..However, no study has evaluated the long-term effects of wound instillation of purified capsaicin on sensory functions...
  64. doi request reprint Prediction of postoperative pain by preoperative pain response to heat stimulation in total knee arthroplasty
    Troels H Lunn
    Department of Anesthesiology, Hvidovre University Hospital, Copenhagen, Denmark
    Pain 154:1878-85. 2013
    ..05 to 0.08). Pain responses to 2 types of preoperative heat stimuli were not independent clinically relevant predictors for postoperative pain after TKA...
  65. doi request reprint Reduced length of stay following hip and knee arthroplasty in Denmark 2000-2009: from research to implementation
    Henrik Husted
    Department of Orthopedic Surgery, Hvidovre University Hospital, Copenhagen, Denmark
    Arch Orthop Trauma Surg 132:101-4. 2012
    ....
  66. doi request reprint Accuracy of the Danish version of the 'distress thermometer'
    Pernille Envold Bidstrup
    Department of Psychosocial Cancer Research, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Psychooncology 21:436-43. 2012
    ..Short screening instruments have been suggested to improve the detection of psychological symptoms. We examined the accuracy of the Danish version of the 'Distress Thermometer'...
  67. doi request reprint Progressive strength training (10 RM) commenced immediately after fast-track total knee arthroplasty: is it feasible?
    Thomas Linding Jakobsen
    Department of Physical Therapy, Clinical Research Centre and Lundbeck Foundation Centre for Fast track Hip and Knee Arthroplasty, Copenhagen University Hospital, Hvidovre, Denmark
    Disabil Rehabil 34:1034-40. 2012
    ..To explore the feasibility of progressive strength training commenced immediately after total knee arthroplasty (TKA)...
  68. ncbi request reprint The effect of accelerated rehabilitation on recovery after surgery for ovarian malignancy
    Charlotte Marx
    Department of Gynecology, The Juliane Marie Centre, Rigshospitalet, Copenhagen University Hospital, Denmark
    Acta Obstet Gynecol Scand 85:488-92. 2006
    ..The aim of this study was to evaluate the postoperative outcome after surgery for ovarian malignancy with conventional care compared to fast-track multimodal rehabilitation...
  69. ncbi request reprint Future perspectives and research initiatives in fast-track surgery
    Henrik Kehlet
    Section for Surgical Pathophysiology, The Juliane Marie Centre, 4074, Rigshospitalet, 2100 Copenhagen, Denmark
    Langenbecks Arch Surg 391:495-8. 2006
    ..The aim of this article was to update recent data on fast-track abdominal surgery and outline future strategies for research...
  70. ncbi request reprint Chronic pain after childhood groin hernia repair
    Eske Kvanner Aasvang
    Section of Surgical Pathophysiology, The Juliane Marie Centre, 2100 Copenhagen, Denmark
    J Pediatr Surg 42:1403-8. 2007
    ..Studies of other childhood surgery before the age of 3 months suggest a risk of increased pain responsiveness later in life, but its potential relationship to chronic pain in adult life is unknown...
  71. doi request reprint Serotonin transporter binding in the hypothalamus correlates negatively with tonic heat pain ratings in healthy subjects: a [11C]DASB PET study
    Ron Kupers
    Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Neuroimage 54:1336-43. 2011
    ..The negative correlation between SERT binding in the hypothalamus and insula with tonic pain ratings suggests a possible serotonergic control of the role of these areas in the modulation or in the affective appreciation of pain...
  72. doi request reprint Local infiltration analgesia in urogenital prolapse surgery: a prospective randomized, double-blind, placebo-controlled study
    Billy B Kristensen
    Department of Anesthesiology, Hvidovre University Hospital, Kettegard Alle 30, Copenhagen, Denmark
    Acta Obstet Gynecol Scand 90:1121-5. 2011
    ..To evaluate the analgesic effect of high-volume infiltration analgesia in urogenital prolapse surgery and provide a detailed description of the infiltration technique...
  73. doi request reprint The effect of wound instillation of a novel purified capsaicin formulation on postherniotomy pain: a double-blind, randomized, placebo-controlled study
    Eske K Aasvang
    Section of Surgical Pathophysiology, The Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark
    Anesth Analg 107:282-91. 2008
    ..Purified capsaicin (ALGRX 4975 98% pure) has demonstrated prolong inhibition of C-fiber function in in vitro, preclinical, and clinical studies, and may be an effective adjunct to postoperative pain management...
  74. pmc Pain and functional impairment 1 year after inguinal herniorrhaphy: a nationwide questionnaire study
    M Bay-Nielsen
    Department of Surgical Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark
    Ann Surg 233:1-7. 2001
    ..To determine the incidence of groin pain 1 year after inguinal herniorrhaphy and to assess the influence of chronic groin pain on function...
  75. doi request reprint Orthostatic function and the cardiovascular response to early mobilization after breast cancer surgery
    R G Muller
    Section of Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Br J Anaesth 104:298-304. 2010
    ..We investigated the cardiovascular response and the incidence of orthostatic intolerance during early mobilization after breast cancer surgery...
  76. doi request reprint Analgesic efficacy of subcutaneous local anaesthetic wound infiltration in bilateral knee arthroplasty: a randomised, placebo-controlled, double-blind trial
    L Ø Andersen
    Department of Anaesthesiology, Hvidovre Hospital, Copenhagen, Denmark
    Acta Anaesthesiol Scand 54:543-8. 2010
    ..High-volume wound local infiltration analgesia is effective in knee arthroplasty, but the analgesic efficacy of subcutaneous wound infiltration has not been evaluated...
  77. ncbi request reprint Neoadjuvant chemotherapy as ovarian cancer treatment: ever more used with major regional differences
    Carsten L Fagö-Olsen
    Gynækologisk Afdeling, Sektion 7821, Juliane Marie Centret, Rigshospitalet, 2100 Copenhagen, Denmark
    Dan Med J 59:A4477. 2012
    ..The aim of this study was to investigate the use of NACT in Denmark in regard to increased use and regional differences...
  78. doi request reprint Pulsed radiofrequency in the treatment of persistent pain after inguinal herniotomy: a systematic review
    Mads U Werner
    Multidisciplinary Pain Center, Rigshospitalet, Copenhagen University, Denmark
    Reg Anesth Pain Med 37:340-3. 2012
    ..In conclusion, the evidence base of PRF in persistent pain after inguinal herniotomy is fairly limited. Suggestions for improved research strategies are presented...
  79. doi request reprint Dysejaculation after laparoscopic inguinal herniorrhaphy: a nationwide questionnaire study
    Joakim M Bischoff
    Section of Surgical Pathophysiology 4074, Rigshospitalet, Copenhagen University, Blegdamsvej 9, 2100, Copenhagen, Denmark
    Surg Endosc 26:979-83. 2012
    ..The aim of this questionnaire study is to assess the prevalence of dysejaculation and pain during sexual activity after laparoscopic inguinal herniorrhaphy on a nationwide basis...
  80. ncbi request reprint Pain related sexual dysfunction after inguinal herniorrhaphy
    Eske Kvanner Aasvang
    Section of Surgical Pathophysiology, The Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark
    Pain 122:258-63. 2006
    ..Intraoperative nerve damage and disposition to other chronic pain conditions are among the most likely pathogenic factors...
  81. doi request reprint Chronic post-thoracotomy pain: a critical review of pathogenic mechanisms and strategies for prevention
    Kim Wildgaard
    Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    Eur J Cardiothorac Surg 36:170-80. 2009
    ..However, intercostal nerve injury seems to be the most important pathogenic factor. Since there is a general agreement on the clinical relevance of PTPS, a proposal for design of future trials is presented...
  82. ncbi request reprint Prolonged length of stay and many readmissions after appendectomy
    Lars Søndergaard Johansen
    Department of Paediatric Surgery, Rigshospitalet, Børnekirurgisk Afdeling C, Rigshospitalet, 2100 København Ø, Denmark
    Dan Med Bull 58:A4296. 2011
    ..The epidemiology of appendicitis seems to be changing; the proportion of complicated appendicitis cases is growing. The outcome of childhood appendectomy in Denmark has not previously been evaluated nationwide in Denmark...
  83. ncbi request reprint Neurophysiological characterization of postherniotomy pain
    Eske Kvanner Aasvang
    Section of Surgical Pathophysiology, 4074, The Juliane Marie Center, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Pain 137:173-81. 2008
    ..Whether the underlying pathophysiological mechanisms are related to direct intraoperative nerve injury or nerve injury due to an inflammatory mesh response remains to be determined...
  84. ncbi request reprint Fast-track colonic surgery: status and perspectives
    Henrik Kehlet
    Section for Surgical Pathophysiology, Rigshospitalet, Section 4074, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Recent Results Cancer Res 165:8-13. 2005
    ..Further data are needed from multi-national institutions on morbidity, safety, and costs...
  85. doi request reprint The effect of mesh removal and selective neurectomy on persistent postherniotomy pain
    Eske K Aasvang
    Copenhagen University, Denmark
    Ann Surg 249:327-34. 2009
    ..Because previous reports on the effect of neurectomy and/or mesh removal suffer from methodological problems we performed a detailed prospective trial of the effect of neurectomy and mesh removal on persistent postherniotomy pain...
  86. doi request reprint Characterization of a novel model of tonic heat pain stimulation in healthy volunteers
    Arne L G Naert
    Department of Surgical Pathophysiology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Pain 138:163-71. 2008
    ..The model can be particularly suitable for brain imaging receptor binding studies which require long stimulation periods...
  87. ncbi request reprint [Early post-operative mobilization and orthostatic intolerance]
    Rasmus Gamborg Müller
    Enhed for Kirurgisk Patofysiologi 4074, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Denmark
    Ugeskr Laeger 173:2183-6. 2011
    ..In reference to find preventive and relevant treatment for OI studies with a multimodal approach have shown promising results, though the pathophysiology behind OI is not fully understood...
  88. doi request reprint Persistent pain after breast cancer treatment: a critical review of risk factors and strategies for prevention
    Kenneth Geving Andersen
    Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
    J Pain 12:725-46. 2011
    ..However, nerve damage and radiotherapy appear to be significant risk factors for chronic pain. A proposal for the design of future prospective studies is presented...
  89. ncbi request reprint Care after colonic operation--is it evidence-based? Results from a multinational survey in Europe and the United States
    Henrik Kehlet
    Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark
    J Am Coll Surg 202:45-54. 2006
    ..This survey investigated clinical practice around colonic operations across Europe and the United States...
  90. ncbi request reprint Wound spread of radiolabeled saline with multi- versus few-hole catheters
    Lasse Ø Andersen
    The Lundbeck Centre for Fast track Hip and Knee Arthroplasty, Department of Anesthesiology, Hvidovre Hospital, Copenhagen, Denmark
    Reg Anesth Pain Med 35:200-2. 2010
    ....
  91. ncbi request reprint Room for improvement in the treatment of hip fractures in Denmark
    Ingrid Egerod
    The University Hospitals Centre for Nursing and Care Research, Rigshospitalet, København Ø, Denmark
    Dan Med Bull 57:A4199. 2010
    ..The aim of our study was to describe the quality of treatment and care related to fast-track hip fracture surgery in Denmark by external audit of patient records...
  92. ncbi request reprint Factors with independent influence on the 'timed up and go' test in patients with hip fracture
    Morten Tange Kristensen
    Lund University, Department of Health Sciences, Division of Physiotherapy, Lund University Hospital, Lasarettsgatan 7, SE 221 85 Lund, Sweden
    Physiother Res Int 14:30-41. 2009
    ..The aims of the present study, therefore, were to assess normative reference values of TUG performances and determine the influence of individual and clinical factors on TUG-test scores in patients with hip fracture...
  93. doi request reprint Knee-extension strength, postural control and function are related to fracture type and thigh edema in patients with hip fracture
    Morten T Kristensen
    Lund University, Department of Health Sciences, Division of Physical Therapy, Lund University Hospital, Sweden
    Clin Biomech (Bristol, Avon) 24:218-24. 2009
    ..The aim of this study was to examine the influence of fracture type and post-surgery edema on physical performances in patients with hip fracture...
  94. ncbi request reprint [Adrenalectomy in Denmark 2002-2006]
    Jan Viberg Jepsen
    Urologisk Afdeling, Herlev Hospital, DK 2730 Herlev
    Ugeskr Laeger 170:4113-6. 2008
    ..The advantages are reduced mortality and morbidity, and shorter postoperative hospitalisation. The organization and short-term outcomes of adrenalectomy in Denmark are largely unknown...
  95. ncbi request reprint High inter-tester reliability of the new mobility score in patients with hip fracture
    Morten Tange Kristensen
    Department of Health Sciences, Lund University, Lund, Sweden
    J Rehabil Med 40:589-91. 2008
    ..To assess the inter-tester reliability of the New Mobility Score in patients with acute hip fracture...
  96. ncbi request reprint [Rehabilitation after total knee arthroplasty]
    Bente Holm
    Fysioterapien, Hvidovre Hospital, DK 2650 Hvidovre
    Ugeskr Laeger 171:691-4. 2009
    ..Thus, the indication for and types of rehabilitation programmes need to be studied within the context of fast-track knee arthroplasty...
  97. doi request reprint Preventive analgesia
    Jørgen B Dahl
    Department of Anaesthesia, Centre of Head and Orthopaedics, Rigshospitalet and Copenhagen University, Denmark
    Curr Opin Anaesthesiol 24:331-8. 2011
    ....
  98. ncbi request reprint Danish Hernia Database recommendations for the management of inguinal and femoral hernia in adults
    Jacob Rosenberg
    Department of Surgical Gastroenterology, Herlev Hospital, Denmark
    Dan Med Bull 58:C4243. 2011
    ..These guidelines will also be available at the website for the Danish Hernia Database (www.herniedatabasen.dk). The guidelines will be updated when new substantial evidence becomes available...
  99. ncbi request reprint [Blood transfusion in major orthopaedic surgery]
    Øivind Jans
    Enhed for Kirurgisk Patofysiologi, 4074, Rigshospitalet, 2100 København Ø, Denmark
    Ugeskr Laeger 173:815-7. 2011
    ..Thus, large randomised studies evaluating a restrictive versus a liberal transfusion strategy in a procedure-specific setup are needed...
  100. doi request reprint Loss of knee-extension strength is related to knee swelling after total knee arthroplasty
    Bente Holm
    The Lundbeck Center for Fast Track Hip and Knee Arthroplasty, Copenhagen University Hospital at Hvidovre, Denmark
    Arch Phys Med Rehabil 91:1770-6. 2010
    ..To examine whether changes in knee-extension strength and functional performance are related to knee swelling after total knee arthroplasty (TKA)...
  101. doi request reprint The role of pain for early rehabilitation in fast track total knee arthroplasty
    Bente Holm
    Department of Physiotherapy, Copenhagen University Hospital at Hvidovre, Hvidovre, Denmark
    Disabil Rehabil 32:300-6. 2010
    ..To investigate the relationship between early functional mobility and pain intensity in a fast track program after total knee arthroplasty (TKA)...