Ismail Gogenur

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. ncbi Postoperative circadian disturbances
    Ismail Gogenur
    Department of Surgical Gastroenterology, Herlev Hospital, Denmark
    Dan Med Bull 57:B4205. 2010
  2. doi Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial
    Michael Tvilling Madsen
    Department of Surgical Gastroenterology, University of Copenhagen, Herlev Hospital, Herlev, Denmark
    Surg Laparosc Endosc Percutan Tech 22:215-9. 2012
  3. doi Circadian variation in the response to experimental endotoxemia and modulatory effects of exogenous melatonin
    Mahdi Alamili
    Department of Surgical Gastroenterology, University of Copenhagen, Herlev Hospital, Copenhagen, Denmark and
    Chronobiol Int 30:1174-80. 2013
  4. pmc Postoperative use of non-steroidal anti-inflammatory drugs in patients with anastomotic leakage requiring reoperation after colorectal resection: cohort study based on prospective data
    Mads Klein
    Department of Surgery, Herlev Hospital, University of Copenhagen, 2730 Herlev, Denmark
    BMJ 345:e6166. 2012
  5. ncbi Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction
    Natalie L Halladin
    Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark
    In Vivo 28:483-8. 2014
  6. doi Perioperative statin therapy is not associated with reduced risk of anastomotic leakage after colorectal resection
    Anne Sofie Bisgård
    Centre for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark
    Dis Colon Rectum 56:980-6. 2013
  7. ncbi Prevention of parastomal hernia by placement of a polypropylene mesh at the primary operation
    Ismail Gogenur
    Department of Surgical Gastroenterology, University of Copenhagen, Gentofte Hospital, Hellerup, Denmark
    Dis Colon Rectum 49:1131-5. 2006
  8. doi There is no association between the circadian clock gene HPER3 and cognitive dysfunction after noncardiac surgery
    Melissa Voigt Hansen
    Department of Gastroenterology, Surgical Section, D 111, Herlev Hospital, Herlev Ringvej 75 2730 Herlev, Denmark
    Anesth Analg 115:379-85. 2012
  9. doi Effect of melatonin on depressive symptoms and anxiety in patients undergoing breast cancer surgery: a randomized, double-blind, placebo-controlled trial
    Melissa V Hansen
    Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark
    Breast Cancer Res Treat 145:683-95. 2014
  10. doi Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies
    Michael Wilhelmsen
    Department of Surgical Gastroenterology, Herlev Hospital, University of Copenhagen, Herlev, Denmark
    J Pineal Res 51:270-7. 2011

Collaborators

Detail Information

Publications46

  1. ncbi Postoperative circadian disturbances
    Ismail Gogenur
    Department of Surgical Gastroenterology, Herlev Hospital, Denmark
    Dan Med Bull 57:B4205. 2010
    ..It may be indicated in subgroups or if other perioperative treatment algorithms were used, but this has to be investigated in future trials...
  2. doi Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial
    Michael Tvilling Madsen
    Department of Surgical Gastroenterology, University of Copenhagen, Herlev Hospital, Herlev, Denmark
    Surg Laparosc Endosc Percutan Tech 22:215-9. 2012
    ..There was a significant drop in ascorbic acid at 1 hour and 6 hours after the first abdominal incision (P=0.002) for all 19 patients. Laparoscopic surgery was not found to be associated with reduced oxidative stress...
  3. doi Circadian variation in the response to experimental endotoxemia and modulatory effects of exogenous melatonin
    Mahdi Alamili
    Department of Surgical Gastroenterology, University of Copenhagen, Herlev Hospital, Copenhagen, Denmark and
    Chronobiol Int 30:1174-80. 2013
    ..The effect of circadian time on the endotoxemia response and possible modulatory effects of melatonin need further investigations in a human endotoxemia model. ..
  4. pmc Postoperative use of non-steroidal anti-inflammatory drugs in patients with anastomotic leakage requiring reoperation after colorectal resection: cohort study based on prospective data
    Mads Klein
    Department of Surgery, Herlev Hospital, University of Copenhagen, 2730 Herlev, Denmark
    BMJ 345:e6166. 2012
    ..To evaluate the effect of postoperative use of non-steroidal anti-inflammatory drugs (NSAIDs) on anastomotic leakage requiring reoperation after colorectal resection...
  5. ncbi Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction
    Natalie L Halladin
    Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark
    In Vivo 28:483-8. 2014
    ..To test whether melatonin reduces oxidative and inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction...
  6. doi Perioperative statin therapy is not associated with reduced risk of anastomotic leakage after colorectal resection
    Anne Sofie Bisgård
    Centre for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark
    Dis Colon Rectum 56:980-6. 2013
    ..Several studies have demonstrated the beneficial pleiotropic effects of statins, and preliminary studies have suggested that perioperative statin treatment may be associated with reduced risk of anastomotic leakage...
  7. ncbi Prevention of parastomal hernia by placement of a polypropylene mesh at the primary operation
    Ismail Gogenur
    Department of Surgical Gastroenterology, University of Copenhagen, Gentofte Hospital, Hellerup, Denmark
    Dis Colon Rectum 49:1131-5. 2006
    ..We studied the safety and prophylactic effect of placing a newly designed polypropylene mesh in an onlay position at the primary operation...
  8. doi There is no association between the circadian clock gene HPER3 and cognitive dysfunction after noncardiac surgery
    Melissa Voigt Hansen
    Department of Gastroenterology, Surgical Section, D 111, Herlev Hospital, Herlev Ringvej 75 2730 Herlev, Denmark
    Anesth Analg 115:379-85. 2012
    ..We hypothesized that patients with the PER3(5/5) genotype would have an increased risk of postoperative cognitive dysfunction (POCD) 1 week after noncardiac surgery...
  9. doi Effect of melatonin on depressive symptoms and anxiety in patients undergoing breast cancer surgery: a randomized, double-blind, placebo-controlled trial
    Melissa V Hansen
    Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark
    Breast Cancer Res Treat 145:683-95. 2014
    ..No differences in side effects were found (P = 0.78). Melatonin significantly reduced the risk of depressive symptoms in women with breast cancer during a three-month period after surgery...
  10. doi Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies
    Michael Wilhelmsen
    Department of Surgical Gastroenterology, Herlev Hospital, University of Copenhagen, Herlev, Denmark
    J Pineal Res 51:270-7. 2011
    ..In this paper, we review the current evidence regarding the analgesic properties of melatonin in animals and humans with chronic pain...
  11. doi Incisional hernia after open versus laparoscopic sigmoid resection
    Lars Peter Holst Andersen
    Department of Surgical Gastroenterology, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
    Surg Endosc 22:2026-9. 2008
    ..Data regarding the long-term hernia risk after laparoscopic colonic surgery are lacking in the literature. In the present study we compared the long-term hernia incidence after laparoscopic versus open sigmoid resection...
  12. pmc Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial
    Mahdi Alamili
    Department of Surgical Gastroenterology, University of Copenhagen, Herlev Hospital, Herlev, Denmark
    PLoS ONE 9:e87413. 2014
    ..Little is known about the relationship between circadian rhythm and sepsis in humans. We aimed to investigate circadian variations in the host response in a human endotoxaemia model...
  13. ncbi [Procedure specific pain management in relation to laparoscopic colonic surgery]
    Lars Peter Holst Andersen
    Afdeling D, Gastroenheden, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark
    Ugeskr Laeger 175:721-5. 2013
    ..Moreover, side effects of the analgesics are presented and individually discussed in relation to the specific procedure. We present recommendations for pain management in relation to laparoscopic colonic resection...
  14. doi Psychological and physical stress among experienced and inexperienced surgeons during laparoscopic cholecystectomy
    Lars Peter Holst Andersen
    Department of Surgical Gastroenterology D, Centre for Perioperative Optimization, Herlev Hospital, University of Copenhagen, Herlev, Denmark
    Surg Laparosc Endosc Percutan Tech 22:73-8. 2012
    ..We investigated the impact of surgical experience on surgeons' stress levels and how perioperative sleep quality may influence surgical performance...
  15. doi Disturbances in the circadian pattern of activity and sleep after laparoscopic versus open abdominal surgery
    Ismail Gogenur
    Department of Surgical Gastroenterology D, University of Copenhagen, Herlev Hospital, Herlev, Denmark
    Surg Endosc 23:1026-31. 2009
    ....
  16. ncbi [Risk of anastomotic leakage in postoperative treatment with non-steroidal anti-inflammatory drugs]
    Mads Klein
    Herlev Hospital, Gastroenheden Kirurgisk Sektion, Denmark
    Ugeskr Laeger 172:1660-2. 2010
    ..We recommend that diclofenac and celecoxib be omitted from analgesic regimens after colorectal surgery involving an anastomosis...
  17. doi Psychological and physical stress in surgeons operating in a standard or modern operating room
    Mads Klein
    Department of Surgical Gastroenterology, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Herlev, Denmark
    Surg Laparosc Endosc Percutan Tech 20:237-42. 2010
    ..The aim of this study was to examine whether optimized ergonomics and technical aids within a modern operating room (OR) affect psychological and physiological stress in experienced laparoscopic surgeons...
  18. ncbi [Renal cell carcinoma with metachronous metastases to the gallbladder after two years]
    Bülent Kücükakin
    Kirurgisk Gastroenterologisk Afdeling D, Gentofte Hospital, DK 2900 Hellerup
    Ugeskr Laeger 171:2486-7. 2009
    ..Ultrasound examination after 1 year revealed a polypoid gallbladder mass. Immunohistochemical examination confirmed the metastasis diagnosis originating from the primary kidney tumour...
  19. doi Oxidative stress in relation to surgery: is there a role for the antioxidant melatonin?
    Bülent Kücükakin
    Department of Surgical Gastroenterology D, University of Copenhagen, Gentofte Hospital, Hellerup, Denmark
    J Surg Res 152:338-47. 2009
    ..This review summarizes the results of animal and human studies wherein melatonin was shown to modulate oxidative stress; this discussion emphasizes the stress response related to surgery...
  20. doi Melatonin reduces cardiac morbidity and markers of myocardial ischemia after elective abdominal aortic aneurism repair: a randomized, placebo-controlled, clinical trial
    Ismail Gogenur
    Department of Surgery, University of Copenhagen, Herlev Hospital, Herlev, Denmark
    J Pineal Res 57:10-5. 2014
    ..Melatonin treatment in the perioperative period decreased clinical cardiac morbidity as well as the occurrence of myocardial ischemia after abdominal aortic aneurism repair. ..
  21. doi Extralevatory abdominoperineal excision (ELAPE) does not result in reduced rate of tumor perforation or rate of positive circumferential resection margin: a nationwide database study
    Mads Klein
    Department of Surgery D, Herlev Hospital, University of Copenhagen, Herlev Ringvej Herlev, Denmark
    Ann Surg 261:933-8. 2015
    ..To evaluate the oncological results and possible benefits associated with extralevatory abdominoperineal excision (ELAPE) when compared with conventional abdominoperineal excision (APE)...
  22. doi Lack of circadian variation and reduction of heart rate variability in women with breast cancer undergoing lumpectomy: a descriptive study
    Melissa V Hansen
    Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark
    Breast Cancer Res Treat 140:317-22. 2013
    ..05) and rMSSD (p < 0.05). This variation was missing for both PO1 and PO14. Patients had a shift of autonomic tone with reduced parasympathetic activity and lack of circadian variation 14 days after lumpectomy. ..
  23. doi Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model
    Mahdi Alamili
    Department of Surgical Gastroenterology, University of Copenhagen, Herlev Hospital, Denmark Electronic address
    J Crit Care 29:184.e9-184.e13. 2014
    ..Melatonin used as an exogenous drug has been documented to have potent antioxidant and anti-inflammatory effects in animal model. We aimed to examine the effect of melatonin in an experimental human sepsis model...
  24. doi Prevention of contrast-induced nephropathy in STEMI patients undergoing primary percutaneous coronary intervention: a systematic review
    Sarah Victoria Ekeløf Busch
    Centre for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark
    J Interv Cardiol 26:97-105. 2013
    ..To evaluate the current prophylactic strategies against CIN in patients with STEMI treated by primary percutaneous coronary intervention...
  25. ncbi [Anxiolytical, analgesic and sedative effects of melatonin in the perioperative phase]
    Michael Wilhelmsen
    Gastroenheden, Kirurgisk Sektion, Herlev Hospital, 2730 Herlev, Denmark
    Ugeskr Laeger 173:1424-7. 2011
    ..Studies show an effect in favour of medication with melatonin with regards to sedation and anxiety but the effect on analgesia has yet to be clarified with further clinical studies...
  26. pmc Decreased heart rate variability in surgeons during night shifts
    Ilda Amirian
    The Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark
    Can J Surg 57:300-4. 2014
    ..Low HRV has been associated with death and increased risk of cardiac events in the general population. The aim of this study was to clarify the effect of a 17-hour night shift on surgeons' HRV...
  27. ncbi Admission medical records made at night time have the same quality as day and evening time records
    Ilda Amirian
    Kirurgisk afdeling, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark
    Dan Med J 61:A4868. 2014
    ..Surgeons' performance might be affected during night shifts due to sleep deprivation. The aim of the study was to assess the quality of admission medical records during day, evening and night time...
  28. doi Pharmacological attenuation of myocardial reperfusion injury in a closed-chest porcine model: a systematic review
    Sarah Ekeløf
    Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark
    J Cardiovasc Transl Res 7:570-80. 2014
    ..The systematic review was performed according to the PRISMA guidelines. ..
  29. doi Analgesic treatment in laparoscopic gastric bypass surgery: a systematic review of randomized trials
    Lars P H Andersen
    Department of Surgery D, Herlev Hospital, University of Copenhagen, 2730, Herlev, Denmark
    Obes Surg 24:462-70. 2014
    ..This review documents a need for high-quality, procedure-specific literature concerning analgesic treatment in LRYGB surgery. ..
  30. ncbi Intracoronary and systemic melatonin to patients with acute myocardial infarction: protocol for the IMPACT trial
    Natalie L Halladin
    Department of Surgery, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark
    Dan Med J 61:A4773. 2014
    ..Given intracoronarily, it enables melatonin to work directly at the site of reperfusion. We wish to test if melatonin, as an antioxidant, can minimise the reperfusion injury following pPCI in patients with AMI...
  31. doi Reduced oxidative stress in STEMI patients treated by primary percutaneous coronary intervention and with antioxidant therapy: a systematic review
    Sarah Ekeløf
    Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark
    Cardiovasc Drugs Ther 28:173-81. 2014
    ..Oxidative stress is one of the major factors contributing to IRI. This systematic review focuses on the effect of antioxidant therapy on reperfusion triggered oxidative stress and myocardial IRI in patients with STEMI...
  32. ncbi Emergence delirium
    Louise Munk
    Department of Anaesthesiology I, Herlev Hospital, University of Copenhagen, DK 2730 Herlev, Denmark
    J Perioper Pract 23:251-4. 2013
    ..Treatment strategies are discussed. The review concludes that there is a need for guidelines concerning diagnosis and treatment of ED. Risk factors should be investigated further in the clinical setting in the future...
  33. ncbi [Bariatric surgery is more efficient than medical treatment in achieving remission in diabetes mellitus type 2]
    Mads Klein
    Center for Peri operativ Optimering, Gastroenheden, Herlev Hospital, Denmark
    Ugeskr Laeger 175:1029-32. 2013
    ..These procedures should therefore be considered in the treatment of patients with DMII and obesity...
  34. pmc Long-term recurrence and complication rates after incisional hernia repair with the open onlay technique
    Lars Peter Holst Andersen
    Department of Surgery D, Herlev Hospital, University of Copenhagen, 2730 Herlev, Denmark
    BMC Surg 9:6. 2009
    ..The objective of this study was to evaluate the long-term recurrence rate as well as surgical complications in a consecutive group of patients undergoing open repair using an onlay mesh technique...
  35. ncbi Oral antibiotics for perforated appendicitis is not recommended
    Mahdi Alamili
    Herlev Hospital, Gastroenheden, Denmark
    Dan Med Bull 57:A4177. 2010
    ..There is no evidence to support a conversion of the postoperative antibiotic regimen from intravenous to oral administration in patients with acute perforated appendicitis...
  36. doi Rapidly resorbable vs. non-resorbable suture for experimental colonic anastomoses in rats--a randomized experimental study
    Mads Klein
    Herlev Hospital, University of Copenhagen, Center for Perioperative Optimization, Department of Surgical Gastroenterology D, Herlev Ringvej 75, DK 2730 Herlev, Denmark
    Int J Surg 9:332-4. 2011
    ..The aim of this study was to compare a rapidly resorbable suture with a non-resorbable suture in experimental colorectal anastomoses...
  37. ncbi [Good results after Hartmann's operation for rectal cancer in high risk patients]
    Morten Togsverd-Bo
    Herlev Hospital, Gastroenheden, Kirurgisk Sektion, Denmark
    Ugeskr Laeger 172:2675-8. 2010
    ..The purpose of this study was to evaluate the incidence of per- and postoperative complications of low anterior resection and Hartmann's operation (HO) for rectal cancer. The study was performed in a department with a high frequency of HO...
  38. doi New and chronic use of hypnotics after diagnosis with early breast cancer. A retrospective cohort study
    Lærke Toftegård Andersen
    Herlev Hospital, University of Copenhagen, Department of Surgery, Herlev, Denmark
    Acta Oncol 54:704-11. 2015
    ..To determine use and investigate factors associated with use of hypnotics the first year after a diagnosis with breast cancer...
  39. ncbi [Splenic torsion as cause of acute abdomen in children]
    Neel Maria Helvind
    Center for Perioperativ Optimering, Gastroenheden, Herlev Hospital, Denmark
    Ugeskr Laeger 175:587-8. 2013
    ..The recovery was uneventful. The child had a twin brother who on a routine ultrasound examination was found to have a normally positioned spleen. Challenges in diagnosis and treatment of children with splenic torsion is discussed...
  40. pmc Actigraphy for measurement of sleep and sleep-wake rhythms in relation to surgery
    Michael T Madsen
    Department of Surgical Gastroenterology, University of Copenhagen, Herlev Hospital, Herlev, Denmark
    J Clin Sleep Med 9:387-94. 2013
    ..Actigraphy is a tool that can be used to quantify these disturbances. The aim of this manuscript was to present the literature where actigraphy has been used to measure sleep and sleep-wake rhythms in relation to surgery...
  41. ncbi [Genetic polymorphism affects the clinical effects of opioids after surgery]
    Andreas Frydshou
    Anæstesiologisk Afdeling I, Herlev Hospital, Denmark
    Ugeskr Laeger 175:725-8. 2013
    ..If the genetic profile of each patient becomes easier accessible in the future, PPM might be planned accordingly to surgical procedure as well as to genetic profile to avoid post-operative pain and pharmacological adverse effects...
  42. ncbi [Closed-chest porcine model is superior in intervention studies of ischaemia reperfusion injury]
    Sarah Victoria Ekeløf Busch
    Gastroenheden, Kirurgisk Sektion D, Herlev Hospital, Denmark
    Ugeskr Laeger 174:1807-10. 2012
    ..The model is well suited for future interventional studies...
  43. doi Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components
    Bülent Kücükakin
    Department of Surgical Gastroenterology, University of Copenhagen, Herlev Hospital, Herlev, Denmark
    Scand J Clin Lab Invest 71:299-303. 2011
    ..The aim of the study was to evaluate the quality of buffy-coat reduced red cells in SAG-M additive solution, by assessing biomarkers of oxidative and inflammatory stress during a storage period of 35 days...
  44. doi Acute complicated diverticulitis managed by laparoscopic lavage
    Mahdi Alamili
    Department of Surgery D, Herlev Hospital, Herlev, Denmark
    Dis Colon Rectum 52:1345-9. 2009
    ..The aim of this review was to give an overview of the literature for this new approach and to determine the safety compared with Hartmann's procedure for patients with acute complicated sigmoid diverticulitis...
  45. pmc The effect of MELatOnin on Depression, anxietY, cognitive function and sleep disturbances in patients with breast cancer. The MELODY trial: protocol for a randomised, placebo-controlled, double-blinded trial
    Melissa Voigt Hansen
    Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark
    BMJ Open 2:e000647. 2012
    ..The PER3 genotype is also to be determined in blood samples...
  46. ncbi Disturbances in melatonin, cortisol and core body temperature rhythms after major surgery
    Ismail Gogenur
    Department of Surgical Gastroenterology, University Hospital of Copenhagen, Gentofte, Niels Andersens Vej 65, DK 2900, Hellerup, Denmark
    World J Surg 31:290-8. 2007
    ..The objective of this study was to examine the profile of melatonin, cortisol and core body temperature rhythms before and after major surgery...