Research Topics
Species | Ulla Feldt-RasmussenSummaryAffiliation: Copenhagen University Hospital Country: Denmark Publications
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Detail Information
Publications
Affective symptoms and cognitive functions in the acute phase of Graves' thyrotoxicosisAsmus Vogel
Memory Disorders Research Group, Department of Neurology, Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, N6702 9, Blegdamsvej 2100 Copenhagen, Denmark
Psychoneuroendocrinology 32:36-43. 2007..Reports of cognitive dysfunction may reflect affective and somatic manifestations of thyrotoxicosis and in most patients these symptoms disappear after treatment of Graves' thyrotoxicosis...
Factors influencing the adrenocorticotropin test: role of contemporary cortisol assays, body composition, and oral contraceptive agentsMarianne Klose
Department of Medical Endocrinology, PE2131, Copenhagen University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
J Clin Endocrinol Metab 92:1326-33. 2007..The normal cortisol response to an ACTH test remains inconsistently defined, possibly caused by various subject- and test- condition-related factors...
Results and summary of voting among the audience during presentation and discussion of Medullary Thyroid Carcinoma clinical guidelines prepared by American Thyroid AssociationUlla Feldt-Rasmussen
Department of Medical Endocrinology, National University Hospital, Copenhagen University, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
Thyroid Res 6:S12. 2013....
Endocrine disorders in pregnancy: physiological and hormonal aspects of pregnancyUlla Feldt-Rasmussen
Dept of Medical Endocrinology, Rigshospitalet, University of Copenhagen, Denmark
Best Pract Res Clin Endocrinol Metab 25:875-84. 2011..Regulation of the foetal endocrine system relies, to some extent, on precursors secreted by placenta and/or mother...
Antithyroid drug therapy: predictive parametersU Feldt-Rasmussen
Department of Medical Endocrinology, Rigshospitalet, University Hospital, Copenhagen, Denmark
Z Arztl Fortbild Qualitatssich 93:53-5. 1999....
Aspects of growth hormone deficiency and replacement in elderly hypopituitary adultsUlla Feldt-Rasmussen
Department of Endocrinology PE 2132, National University Hospital, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
Growth Horm IGF Res 14:S51-8. 2004..These data indicate a positive benefit from GH replacement in older patients with hypopituitarism - particularly in relation to quality of life - using a lower dose of GH for replacement and with appropriate age-related safety controls...
Treatment of hypothyroidism in elderly patients and in patients with cardiac diseaseUlla Feldt-Rasmussen
Department of Medical Endocrinology, Rigshospitalet, National University Hospital, Copenhagen, Denmark
Thyroid 17:619-24. 2007..It may be relevant to treat the cardiac vascular occlusion before starting replacement with levothyroxine in some cases, after careful weighting of pros and cons in each individual case...
Thyroid and leptinUlla Feldt-Rasmussen
Department of Medical Endocrinology, Rigshospitalet, National University Hospital, Copenhagen, Denmark
Thyroid 17:413-9. 2007..Despite intensive research in this field, results are still not very clear. The aim of this review has been to update the current state of knowledge of leptin related to thyroid pathophysiology...
Fabry disease--a metabolic disorder with a challenge for endocrinologists?U Feldt-Rasmussen
Department of Medical Endocrinology, Rigshospitalet, Institute of Medical Biochemistry and Genetics, University of Copenhagen, Denmark
Horm Res 58:259-65. 2002..To revisit Fabry disease, a rare X-linked metabolic glycosphingolipid storage disease caused by a deficiency of the lysosomal enzyme alpha-galactosidase A (alpha-gal A)...
Autoimmunity in differentiated thyroid cancer: significance and related clinical problemsUlla Feldt-Rasmussen
Department of Medical Endocrinology, Rigshospitalet, National University Hospital, Copenhagen, Denmark
Hormones (Athens) 9:109-17. 2010..However, in such cases serial TgAb measurements may be used as a surrogate marker for recurrence of thyroid cancer during the long-term monitoring of DTC patients...
Can bone loss be reversed by antithyroid drug therapy in premenopausal women with Graves' disease?Tina Z Belsing
Department of Endocrinology, National University Hospital, Rigshospitalet, Copenhagen, Denmark
Nutr Metab (Lond) 7:72. 2010..Hyperthyroidism can lead to reduced bone mineral density (BMD) and increased fracture risk particularly in postmenopausal women, but the mechanism behind is still unclear...
Fabry disease: a new challenge in endocrinology and metabolism?U Feldt-Rasmussen
Department of Medical Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Eur J Endocrinol 146:741-2. 2002
Diagnostic dilemma: a young woman with Fabry disease symptoms, no family history, and a "sequencing cryptic" α-galactosidase a large deletionUlla Feldt-Rasmussen
Department of Medical Endocrinology, National University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
Mol Genet Metab 104:314-8. 2011..Thus, gene dosage analyses can detect large deletions (>50bp) in suspect heterozygotes for X-linked and autosomal dominant diseases that are "sequencing cryptic," resolving molecular diagnostic dilemmas...
Growth hormone deficiency and replacement in hypopituitary patients previously treated for acromegaly or Cushing's diseaseUlla Feldt-Rasmussen
Department of Endocrinology, Rigshospitalet, National University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
Eur J Endocrinol 146:67-74. 2002..To study the effects of GH therapy in those patients who had completed at least 6 months of GH replacement...
Iodine and cancerU Feldt-Rasmussen
Department of Medical Endocrinology, National University Hospital, Rigshospitalet, Copenhagen University, Denmark
Thyroid 11:483-6. 2001..The overall incidence for a relationship between iodine and cancer is poor and future studies are warranted...
Interactions between growth hormone and the thyroid gland -- with special reference to biochemical diagnosisUlla Feldt-Rasmussen
Department of Medical Endocrinology, Rigshospitalet, National University Hospital, Copenhagen, Denmark
Curr Med Chem 14:2783-8. 2007..Only then can the diagnostic accuracy and the management of patients with both growth hormone and thyroid disorders be improved...
Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults - a KIMS database analysisRoger Abs
Department of Endocrinology, University Hospital, Antwerp, Belgium
Eur J Endocrinol 155:79-90. 2006..The aim of the present study was to clarify the relationship between GH deficiency (GHD) and some cardiovascular risk factors and to analyse the effect of GH replacement therapy in a large number of patients over a prolonged period of time...
High risk of adrenal insufficiency in adults previously treated for idiopathic childhood onset growth hormone deficiencyMartin Lange
Department of Endocrinology, Rigshospitalet, DK 2100 Copenhagen, Denmark
J Clin Endocrinol Metab 88:5784-9. 2003..It is imperative that pituitary axes other than the GH axis are tested at regular intervals, even in the absence of GHD in adulthood...
Association of thyroid gland volume, serum insulin-like growth factor-I, and anthropometric variables in euthyroid prepubertal childrenMalene Boas
University Department of Growth and Reproduction, Rigshospitalet, DK 2100 Copenhagen, Denmark
J Clin Endocrinol Metab 94:4031-5. 2009..We have investigated thyroid gland volume and several hormonal and anthropometric variables in prepubertal children...
Antithyroid drug-induced fetal goitrous hypothyroidismSofie Bliddal
Department of Medical Endocrinology, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark
Nat Rev Endocrinol 7:396-406. 2011..The best way to avoid maternal overtreatment with antithyroid drugs is to monitor closely the maternal thyroid status, especially estimates of free T(4) levels...
Abnormal sympathoadrenal activity, but normal energy expenditure in hypopituitarismHenriette Mersebach
Department of Endocrinology, Copenhagen University Hospital, DK 2100 Copenhagen, Denmark
J Clin Endocrinol Metab 88:5689-95. 2003..This may reflect a central defect in hypopituitarism, however the possible impact of long-term GH and hydrocortisone treatment requires further attention...
Which domains of thyroid-related quality of life are most relevant? Patients and clinicians provide complementary perspectivesTorquil Watt
Department of Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Thyroid 17:647-54. 2007..To identify how thyroid diseases impact the patients' lives and to select the most relevant quality of life (QoL) issues for a thyroid-specific questionnaire...
Improving a newly developed patient-reported outcome for thyroid patients, using cognitive interviewingTorquil Watt
Department of Endocrinology, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark
Qual Life Res 17:1009-17. 2008..To improve a newly developed patient-reported outcome measure for thyroid patients using cognitive interviewing...
Abnormal bone collagen morphology and decreased bone strength in growth hormone-deficient ratsMartin Lange
Department of Endocrinology and Nephrology, Rigshospitalet, Copenhagen, Denmark
Bone 35:178-85. 2004..Whether similar conditions are present in GHD patients need further investigations. The changes described, however, may provide a co-explanation for the increased fracture rate in GHD...
Thyrotropin-releasing hormone stimulation test in patients with pituitary pathologyMarie Louise Hartoft-Nielsen
Department of Endocrinology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
Horm Res 61:53-7. 2004..To evaluate the value of the thyrotropin-releasing hormone (TRH) stimulation test in the diagnostic work-up of the thyroid function in patients with pituitary pathology...
Combined dietary and pharmacological weight management in obese hypopituitary patientsHenriette Mersebach
Department of Endocrinology, Copenhagen University Hospital 9, Blegdamsvej DK 2100 Copenhagen, Denmark
Obes Res 12:1835-43. 2004..In this study, we investigated the combined effect of sibutramine, diet, and exercise in obese hypopituitary patients (HPs)...
Quality of life in patients with benign thyroid disorders. A reviewTorquil Watt
Department of Endocrinology, Copenhagen University Hospital, Rigshospitalet, Denmark
Eur J Endocrinol 154:501-10. 2006..Studies systematically exploring the relative importance of these various aspects to thyroid patients are lacking, as is a comprehensive, validated thyroid-specific HRQL questionnaire...
Narrow intra-individual variation of maternal thyroid function in pregnancy based on a longitudinal study on 132 womenMalene Boas
University Department of Growth and Reproduction, GR 5064, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
Eur J Endocrinol 161:903-10. 2009....
Validity and reliability of the novel thyroid-specific quality of life questionnaire, ThyPROTorquil Watt
Department of Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen Ø, Denmark
Eur J Endocrinol 162:161-7. 2010..However, before clinical use, clinical validity and test-retest reliability should be evaluated...
Graves' disease in two pregnancies complicated by fetal goitrous hypothyroidism: successful in utero treatment with levothyroxineSofie Bliddal
Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen University, Copenhagen, Denmark
Thyroid 21:75-81. 2011..Treatment of Graves' disease during pregnancy with antithyroid drugs (ATDs) poses a risk of inducing hypothyroidism and, thus, development of a goiter to the fetus...
GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patientsSimon Doessing
Department of Orthopaedic Surgery M, Faculty of Health Sciences, Institute of Sports Medicine, Bispebjerg Hospital and Centre for Healthy Aging, University of Copenhagen, Bispebjerg Bakke 23, Copenhagen DK 2400, Denmark
Eur J Endocrinol 163:853-62. 2010..GH/IGF1 is likely to play an important role in the regulation of tendon and muscle collagen. We hypothesized that the local production of collagen is associated with the level of GH/IGF1...
Osteopenia: a common aspect of Fabry disease. Predictors of bone mineral densityHenriette Mersebach
Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
Genet Med 9:812-8. 2007..We investigated the bone mineral status in patients with untreated Fabry disease (FD)...
Interleukin-8 production from human somatotroph adenoma cells is stimulated by interleukin-1β and inhibited by growth hormone releasing hormone and somatostatinSigne Diness Vindeløv
Department of Medical Endocrinology, PE 2132, Rigshospitalet, Copenhagen University Hospital, University of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
Growth Horm IGF Res 21:134-9. 2011..We investigated the role of cytokines, in particular interleukin (IL)-8, in the pathogenesis of growth hormone (GH) producing tumours...
Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growthMalene Boas
Department of Growth and Reproduction, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark
Environ Health Perspect 118:1458-64. 2010..Phthalates are widely used chemicals, and human exposure is extensive. Recent studies have indicated that phthalates may have thyroid-disrupting properties...
The impact of idiopathic childhood-onset growth hormone deficiency (GHD) on bone mass in subjects without adult GHDMartin Lange
Department of Endocrinology, Rigshospitalet, Glostrup, Denmark
Clin Endocrinol (Oxf) 62:18-23. 2005..The aim was to evaluate BMD and bone mineral content (BMC) in adults treated for idiopathic childhood-onset (CO) GHD, 18 years after stopping GH treatment...
Signs of maternal vascular dysfunction precede preeclampsia in women with type 1 diabetesPeter Clausen
Department of Nephrology and Endocrinology, Copenhagen University Hospital, Rigshospitalet, DK 2100, Copenhagen, Denmark
J Diabetes Complications 21:288-93. 2007..This study aims to test the hypothesis that vascular dysfunction is present early in pregnancy in women with type 1 diabetes who subsequently develop preeclampsia...
Thyroid effects of endocrine disrupting chemicalsMalene Boas
Department of Growth and Reproduction GR, Rigshospitalet, University of Copenhagen, Denmark
Mol Cell Endocrinol 355:240-8. 2012....
Circulating leptin and thyroid dysfunctionTina Zimmermann-Belsing
Department of Endocrinology, University Hospital, Rigshospitalet, Copenhagen, Denmark
Eur J Endocrinol 149:257-71. 2003..In this review, we have focused on leptin in relation to thyroid pathophysiology...
Escitalopram and neuroendocrine response in healthy first-degree relatives to depressed patients--a randomized placebo-controlled trialUlla Knorr
Department of Psychiatry Copenhagen, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
PLoS ONE 6:e21224. 2011....
Cardiac effects of low-dose growth hormone replacement therapy in growth hormone-deficient adults. An 18-month randomised, placebo-controlled, double-blind studySimone B Sneppen
Department of Endocrinology, The National University Hospital, Copenhagen, Denmark
Horm Res 58:21-9. 2002..CONCLUSION: In adult onset GHD, diastolic dysfunction was present in 40% of the patients. None of the investigated values were different after 18 months of GH compared to placebo...
Unsuccessful radioiodine treatment of a non-toxic goiter: a case reportMarie Louise Hartoft-Nielsen
Department of Medical Endocrinology, Rigshospitalet, University Hospital of Copenhagen, Denmark
Basic Clin Pharmacol Toxicol 95:72-5. 2004..However, this reported case should not discredit the use of radioiodine treatment of non-toxic goiters, but focus on patients with a single large solitary adenoma in whom this treatment may be inappropriate...
Hypopituitarism is uncommon after aneurysmal subarachnoid haemorrhageMarianne Klose
Department of Medical Endocrinology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark
Clin Endocrinol (Oxf) 73:95-101. 2010..We aimed at estimating the risk of hypopituitarism after SAH using strict criteria including confirmatory testing in case of suggested insufficiency...
Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnanciesPia Ekbom
The Endocrine Clinic, 2The Obstetric Clinic, The National University Hospital, DK 2100 Copenhagen, Denmark
Acta Obstet Gynecol Scand 85:143-7. 2006..The aim was to investigate whether activin A and inhibin A in serum were elevated in type I diabetic women after developing pre-eclampsia and, if so, were they clinically useful as predictors of pre-eclampsia...
Establishing construct validity for the thyroid-specific patient reported outcome measure (ThyPRO): an initial examinationTorquil Watt
Department of Endocrinology, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark
Qual Life Res 18:483-96. 2009..To establish a reliable and valid scale structure of a patient-reported outcome measuring thyroid-specific quality of life...
Do Thyroid Disrupting Chemicals Influence Foetal Development during Pregnancy?Marie Louise Hartoft-Nielsen
Department of Medical Endocrinology PE 2131, Rigshospitalet, University Hospital of Copenhagen, 2100 Copenhagen, Denmark
J Thyroid Res 2011:342189. 2011..Knowledge of the effects is expected to impact the general debate on the use of these chemicals. However, more studies are needed to elucidate the issue, since human studies are scarce...
An audit of the insulin-tolerance test in 255 patients with pituitary diseaseMartin Lange
Department of Endocrinology, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark
Eur J Endocrinol 147:41-7. 2002..It was confirmed that IGF-I is not sufficient when diagnosing GHD in adults, and reliable stimulation tests like ITT are required in the diagnosis...
Ultrasonically measured horizontal eye muscle thickness in thyroid associated orbitopathy: cross-sectional and longitudinal aspects in a Danish seriesHans C Fledelius
Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Denmark
Acta Ophthalmol Scand 81:143-50. 2003..To analyse horizontal extraocular muscle findings by ultrasound and exophthalmometry in a tertiary endocrinology centre series of patients with thyroid associated orbitopathy (TAO)...
Pegvisomant treatment in a 4-year-old girl with neurofibromatosis type 1Katharina M Main
University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
Horm Res 65:1-5. 2006..Recently, a GH receptor antagonist, pegvisomant, was introduced for the treatment of adults with acromegaly. We wanted to investigate whether pegvisomant was effective in a child with octreotide-resistant GH excess...
Is increase in bone mineral content caused by increase in skeletal muscle mass/strength in adult patients with GH-treated GH deficiency? A systematic literature analysisOliver Klefter
Department of Medical Endocrinology, PE 2131, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
Eur J Endocrinol 161:213-21. 2009....
[Measurement of health-related quality of life in thyroid patients]Torquil Watt
Odense Universitetshospital
Ugeskr Laeger 170:850-2. 2008..This may be due to the lack of a valid HRQL measurement. Hopefully, increased focus on HRQL and the development of a valid thyroid-specific HRQL measure will improve this status...
Response to GH treatment in adult GH deficiency is predicted by gender, age, and IGF1 SDS but not by stimulated GH-peakUlla Feldt-Rasmussen
Department of Medical Endocrinology, PE 2132, Rigshospitalet, National University Hospital, Copenhagen University, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
Eur J Endocrinol 168:733-43. 2013..The patients were divided into three groups of approximately equal size (tertiles) according to the stimulated GH-peak values and baseline IGF1 SDS and were studied at baseline, 12, and 24 months of GH therapy...
Growth hormone and body compositionHenriette Mersebach
Department of Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
Front Horm Res 33:185-95. 2005
Fabry disease mimicking hypertrophic cardiomyopathy: genetic screening needed for establishing the diagnosis in womenOle Havndrup
Department of Cardiology, Heart Centre, The National University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
Eur J Heart Fail 12:535-40. 2010..The 'cardiac variant' of Fabry disease which only affects the heart may be missed unless specifically tested for...
Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid diseaseUlla Feldt-Rasmussen
Department of Medical Endocrinology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
J Thyroid Res 2011:598712. 2011..Measurement of antithyroperoxidase and/or TSH receptor antibodies adds to the differential diagnosis of autoimmune and nonautoimmune thyroid diseases...
Bridging provocative tests and clinical manifestations of growth hormone deficiency in adultsUlla Feldt-Rasmussen
Department of Medical Endocrinology, National University Hospital, Copenhagen, Denmark
Horm Res 68:57-8. 2007
Elevated third-trimester haemoglobin A 1c predicts preterm delivery in type 1 diabetesPia Ekbom
Endocrine Clinic, The National University Hospital, Rigshospitalet, Copenhagen, Denmark
J Diabetes Complications 22:297-302. 2008..The adjusted odds ratio per 1% increment in HbA(1c) at 28 weeks of gestation was 2.8 (95% CI 1.7-4.4). HbA(1c) at 28 weeks of gestation was a clinical significant predictor of preterm delivery in type 1 diabetes...
Iodine and tri-iodo-thyronine reduce the incidence of type 1 diabetes mellitus in the autoimmune prone BB ratsMarie Louise Hartoft-Nielsen
Department of Endocrinology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
Autoimmunity 42:131-8. 2009..In Wistar rats T3 treatment increased the beta cell mass per bodyweight. The modulation of thyroid function during postnatal development may thus affect the precipitation of T1DM in genetically susceptible individuals...
Agalsidase beta treatment is associated with improved quality of life in patients with Fabry disease: findings from the Fabry RegistryTorquil Watt
Department of Endocrinology, National University Hospital, Copenhagen, Denmark
Genet Med 12:703-12. 2010..To evaluate the effect of agalsidase beta on longitudinal health-related quality of life in patients with Fabry disease...
Bone mineral content and bone metabolism during physiological GH treatment in GH-deficient adults--an 18-month randomised, placebo-controlled, double blinded trialSimone Bjerregård Sneppen
Department of Endocrinology, National University Hospital, Copenhagen, Denmark
Eur J Endocrinol 146:187-95. 2002..To evaluate the effect of physiological adult growth hormone (GH) replacement on bones...
Environmental chemicals and thyroid function: an updateMalene Boas
University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
Curr Opin Endocrinol Diabetes Obes 16:385-91. 2009..To overview the effects of endocrine disrupters on thyroid function...
Rationale and design of the participant, investigator, observer, and data-analyst-blinded randomized AGENDA trial on associations between gene-polymorphisms, endophenotypes for depression and antidepressive intervention: the effect of escitalopram versus Ulla Knorr
Department of Psychiatry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
Trials 10:66. 2009..Assessments are undertaken by assessors blinded to the randomization group...
Characteristics of the Danish families with multiple endocrine neoplasia type 1Anne Charlotte Jäger
Department of Clinical Biochemistry, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
Mol Cell Endocrinol 249:123-32. 2006..In contrast, sporadic carcinoid tumours or primary prolactinomas are rarely associated with germ-line MEN1 mutations...
Increased risk of osteoporotic fractures in patients with Cushing's syndromePeter Vestergaard
The Osteoporosis Clinic, Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Tage Hansens Gade 2, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
Eur J Endocrinol 146:51-6. 2002..To evaluate if fracture risk was increased in patients with Cushing's syndrome due to the increased endogenous cortisol production...
Mortality and GH deficiency: a nationwide studyKirstine Stochholm
Medical Department M Endocrinology and Diabetes, Aarhus University Hospital, Aarhus Sygehus, NBG, DK 8000 Aarhus C, Denmark
Eur J Endocrinol 157:9-18. 2007..To estimate the mortality in Denmark in patients suffering from GH deficiency (GHD)...
Discontinuation of estrogen replacement therapy in GH-treated hypopituitary women alters androgen status and IGF-IJens Juel Christiansen
Medical Department M, Arhus Sygehus, Arhus University Hospital, , DK-8000 Arhus C, Denmark
Eur J Endocrinol 152:719-26. 2005..These effects may contribute to the gender differences observed in the GH-IGF axis in healthy adults as well as in the responsiveness of hypopituitary patients to GH substitution...
Cotreatment of acromegaly with a somatostatin analog and a growth hormone receptor antagonistJens Otto Lunde Jørgensen
Medical Department M, Aarhus University Hospital, Norrebrogade 44, DK 8000 C Aarhus, Denmark
J Clin Endocrinol Metab 90:5627-31. 2005..Pegvisomant is a GH receptor antagonist that blocks the peripheral actions of GH in acromegaly. Pegvisomant, in contrast to somatostatin (SMS) analogs, does not suppress the activity of the GH-producing adenoma...
Females with Fabry disease frequently have major organ involvement: lessons from the Fabry RegistryWilliam R Wilcox
Medical Genetics Institute, Cedars Sinai Medical Center, 8700 Beverly Blvd SSB, Los Angeles, CA 90048, USA
Mol Genet Metab 93:112-28. 2008..Thus, females with FD have a significant risk for major organ involvement and decreased QoL. Females should be regularly monitored for signs and symptoms of FD, and considered for enzyme replacement therapy...
Isolated growth hormone (GH) deficiency in adult patients: baseline clinical characteristics and responses to GH replacement in comparison with hypopituitary patients. A sub-analysis of the KIMS databaseRoger Abs
Department of Endocrinology, University Hospital Antwerp, Wilrijkstraat 10, B 2650 Edegem, Belgium
Growth Horm IGF Res 15:349-59. 2005....
Effect of growth hormone replacement therapy on pituitary hormone secretion and hormone replacement therapies in GHD adultsErika Hubina
Department of Medicine, National Medical Center, Budapest, Hungary
Horm Res 61:211-7. 2004..Monitoring of pituitary hormone axes is advisable after commencement of GH replacement therapy, since changes of hormone replacement therapy was observed in a small but clinically significant number of patients...
Obesity: the new worldwide epidemic threat to general health and our complete lack of effective treatmentTina Zimmermann-Belsing
Endocrinology 145:1501-2. 2004
Incidence of GH deficiency - a nationwide studyKirstine Stochholm
Medical Department M Endocrinology and Diabetes, Aarhus Sygehus, NBG, DK 8000 Aarhus C, Denmark
Eur J Endocrinol 155:61-71. 2006..Data on incidence rates are scarce in GH deficiency (GHD). Here, we estimate the incidence rate in childhood onset (CO) and adult onset (AO) GHD in Denmark...
Clinical implications of residual growth hormone (GH) response to provocative testing in adults with severe GH deficiencyGeorg Brabant
Department of Endocrinology, Christie Hospital, Wilmslow Road, Manchester M20 4BX, United Kingdom
J Clin Endocrinol Metab 92:2604-9. 2007..It is unknown whether the amount of residual GH reserve under the cutoff value has any physiological implication...
Small-fibre neuropathy in female Fabry patients: reduced allodynia and skin blood flow after topical capsaicinAnette T Moller
Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
J Peripher Nerv Syst 11:119-25. 2006..006) in female Fabry patients. This indicates that female Fabry patients have a significant loss of small-fibre function and demonstrates that it is possible to evaluate this by a non-invasive method...
Distribution of alpha-galactosidase A in normal human kidney and renal accumulation and distribution of recombinant alpha-galactosidase A in Fabry miceErik I Christensen
Department of Cell Biology, Institute of Anatomy, Wilh Meyers Alle, Building 234, University of Aarhus, DK 8000 Aarhus C, Denmark
J Am Soc Nephrol 18:698-706. 2007....
Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid diseaseZubair Baloch
Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, USA
Thyroid 13:3-126. 2003
Morbidity and GH deficiency: a nationwide studyKirstine Stochholm
Medical Department M Endocrinology and Diabetes, Aarhus University Hospital, Aarhus Sygehus, NBG, DK 8000 Aarhus C, Denmark
Eur J Endocrinol 158:447-57. 2008..To estimate morbidity in Denmark in all patients with GH deficiency (GHD)...
Environmental chemicals and thyroid functionMalene Boas
University Department of Growth and Reproduction GR 5064, Copenhagen Denmark
Eur J Endocrinol 154:599-611. 2006..It is therefore urgent to clarify whether the animal data showing effects of chemicals on thyroid function can be extended to humans...
Thyroid autoantibodies and thyroid function in subjects exposed to Chernobyl fallout during childhood: evidence for a transient radiation-induced elevation of serum thyroid antibodies without an increase in thyroid autoimmune diseaseLaura Agate
Department of Endocrinology, University of Pisa, Via Paradisa 2, Pisa, Italy
J Clin Endocrinol Metab 93:2729-36. 2008..An increase in the prevalence of thyroid autoantibodies (ATAs) was reported 6-8 yr after the Chernobyl accident in radiation-exposed children and adolescents...
