Ulla Feldt-Rasmussen

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. ncbi request reprint Affective symptoms and cognitive functions in the acute phase of Graves' thyrotoxicosis
    Asmus Vogel
    Memory Disorders Research Group, Department of Neurology, Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, N6702 9, Blegdamsvej 2100 Copenhagen, Denmark
    Psychoneuroendocrinology 32:36-43. 2007
  2. ncbi request reprint Factors influencing the adrenocorticotropin test: role of contemporary cortisol assays, body composition, and oral contraceptive agents
    Marianne Klose
    Department of Medical Endocrinology, PE2131, Copenhagen University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Clin Endocrinol Metab 92:1326-33. 2007
  3. pmc Introduction to European comments on "Medullary Thyroid Cancer: management guidelines of the American Thyroid Association"
    Barbara Jarzab
    Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Wybrzeze Armii Krajowej 15, 44 101 Gliwice, Poland
    Thyroid Res 6:S1. 2013
  4. doi request reprint Response to GH treatment in adult GH deficiency is predicted by gender, age, and IGF1 SDS but not by stimulated GH-peak
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, PE 2132, Rigshospitalet, National University Hospital, Copenhagen University, Copenhagen, Denmark
    Eur J Endocrinol 168:733-43. 2013
  5. pmc Results and summary of voting among the audience during presentation and discussion of Medullary Thyroid Carcinoma clinical guidelines prepared by American Thyroid Association
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, National University Hospital, Copenhagen University, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Thyroid Res 6:S12. 2013
  6. doi request reprint Endocrine disorders in pregnancy: physiological and hormonal aspects of pregnancy
    Ulla Feldt-Rasmussen
    Dept of Medical Endocrinology, Rigshospitalet, University of Copenhagen, Denmark
    Best Pract Res Clin Endocrinol Metab 25:875-84. 2011
  7. pmc Can bone loss be reversed by antithyroid drug therapy in premenopausal women with Graves' disease?
    Tina Z Belsing
    Department of Endocrinology, National University Hospital, Rigshospitalet, Copenhagen, Denmark
    Nutr Metab (Lond) 7:72. 2010
  8. ncbi request reprint Aspects of growth hormone deficiency and replacement in elderly hypopituitary adults
    Ulla Feldt-Rasmussen
    Department of Endocrinology PE 2132, National University Hospital, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Growth Horm IGF Res 14:S51-8. 2004
  9. doi request reprint Diagnostic dilemma: a young woman with Fabry disease symptoms, no family history, and a "sequencing cryptic" α-galactosidase a large deletion
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, National University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Mol Genet Metab 104:314-8. 2011
  10. ncbi request reprint Autoimmunity in differentiated thyroid cancer: significance and related clinical problems
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, Rigshospitalet, National University Hospital, Copenhagen, Denmark
    Hormones (Athens) 9:109-17. 2010

Detail Information

Publications84

  1. ncbi request reprint Affective symptoms and cognitive functions in the acute phase of Graves' thyrotoxicosis
    Asmus Vogel
    Memory Disorders Research Group, Department of Neurology, Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, N6702 9, Blegdamsvej 2100 Copenhagen, Denmark
    Psychoneuroendocrinology 32:36-43. 2007
    ..Reports of cognitive dysfunction may reflect affective and somatic manifestations of thyrotoxicosis and in most patients these symptoms disappear after treatment of Graves' thyrotoxicosis...
  2. ncbi request reprint Factors influencing the adrenocorticotropin test: role of contemporary cortisol assays, body composition, and oral contraceptive agents
    Marianne Klose
    Department of Medical Endocrinology, PE2131, Copenhagen University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Clin Endocrinol Metab 92:1326-33. 2007
    ..The normal cortisol response to an ACTH test remains inconsistently defined, possibly caused by various subject- and test- condition-related factors...
  3. pmc Introduction to European comments on "Medullary Thyroid Cancer: management guidelines of the American Thyroid Association"
    Barbara Jarzab
    Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Wybrzeze Armii Krajowej 15, 44 101 Gliwice, Poland
    Thyroid Res 6:S1. 2013
    ..It is explained why it has been decided to publish the manuscripts within the supplement - to document voices from the discussion and popularize them...
  4. doi request reprint Response to GH treatment in adult GH deficiency is predicted by gender, age, and IGF1 SDS but not by stimulated GH-peak
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, PE 2132, Rigshospitalet, National University Hospital, Copenhagen University, Copenhagen, Denmark
    Eur J Endocrinol 168:733-43. 2013
    ..The patients were divided into three groups of approximately equal size (tertiles) according to the stimulated GH-peak values and baseline IGF1 SDS and were studied at baseline, 12, and 24 months of GH therapy...
  5. pmc Results and summary of voting among the audience during presentation and discussion of Medullary Thyroid Carcinoma clinical guidelines prepared by American Thyroid Association
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, National University Hospital, Copenhagen University, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Thyroid Res 6:S12. 2013
    ....
  6. doi request reprint Endocrine disorders in pregnancy: physiological and hormonal aspects of pregnancy
    Ulla Feldt-Rasmussen
    Dept of Medical Endocrinology, Rigshospitalet, University of Copenhagen, Denmark
    Best Pract Res Clin Endocrinol Metab 25:875-84. 2011
    ..Regulation of the foetal endocrine system relies, to some extent, on precursors secreted by placenta and/or mother...
  7. pmc Can bone loss be reversed by antithyroid drug therapy in premenopausal women with Graves' disease?
    Tina Z Belsing
    Department of Endocrinology, National University Hospital, Rigshospitalet, Copenhagen, Denmark
    Nutr Metab (Lond) 7:72. 2010
    ..Hyperthyroidism can lead to reduced bone mineral density (BMD) and increased fracture risk particularly in postmenopausal women, but the mechanism behind is still unclear...
  8. ncbi request reprint Aspects of growth hormone deficiency and replacement in elderly hypopituitary adults
    Ulla Feldt-Rasmussen
    Department of Endocrinology PE 2132, National University Hospital, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Growth Horm IGF Res 14:S51-8. 2004
    ..These data indicate a positive benefit from GH replacement in older patients with hypopituitarism - particularly in relation to quality of life - using a lower dose of GH for replacement and with appropriate age-related safety controls...
  9. doi request reprint Diagnostic dilemma: a young woman with Fabry disease symptoms, no family history, and a "sequencing cryptic" α-galactosidase a large deletion
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, National University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Mol Genet Metab 104:314-8. 2011
    ..Thus, gene dosage analyses can detect large deletions (>50bp) in suspect heterozygotes for X-linked and autosomal dominant diseases that are "sequencing cryptic," resolving molecular diagnostic dilemmas...
  10. ncbi request reprint Autoimmunity in differentiated thyroid cancer: significance and related clinical problems
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, Rigshospitalet, National University Hospital, Copenhagen, Denmark
    Hormones (Athens) 9:109-17. 2010
    ..However, in such cases serial TgAb measurements may be used as a surrogate marker for recurrence of thyroid cancer during the long-term monitoring of DTC patients...
  11. ncbi request reprint Interactions between growth hormone and the thyroid gland -- with special reference to biochemical diagnosis
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, Rigshospitalet, National University Hospital, Copenhagen, Denmark
    Curr Med Chem 14:2783-8. 2007
    ..Only then can the diagnostic accuracy and the management of patients with both growth hormone and thyroid disorders be improved...
  12. ncbi request reprint Antithyroid drug therapy: predictive parameters
    U Feldt-Rasmussen
    Department of Medical Endocrinology, Rigshospitalet, University Hospital, Copenhagen, Denmark
    Z Arztl Fortbild Qualitatssich 93:53-5. 1999
    ....
  13. ncbi request reprint Thyroid and leptin
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, Rigshospitalet, National University Hospital, Copenhagen, Denmark
    Thyroid 17:413-9. 2007
    ..Despite intensive research in this field, results are still not very clear. The aim of this review has been to update the current state of knowledge of leptin related to thyroid pathophysiology...
  14. ncbi request reprint Fabry disease--a metabolic disorder with a challenge for endocrinologists?
    U Feldt-Rasmussen
    Department of Medical Endocrinology, Rigshospitalet, Institute of Medical Biochemistry and Genetics, University of Copenhagen, Denmark
    Horm Res 58:259-65. 2002
    ..To revisit Fabry disease, a rare X-linked metabolic glycosphingolipid storage disease caused by a deficiency of the lysosomal enzyme alpha-galactosidase A (alpha-gal A)...
  15. ncbi request reprint Treatment of hypothyroidism in elderly patients and in patients with cardiac disease
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, Rigshospitalet, National University Hospital, Copenhagen, Denmark
    Thyroid 17:619-24. 2007
    ..It may be relevant to treat the cardiac vascular occlusion before starting replacement with levothyroxine in some cases, after careful weighting of pros and cons in each individual case...
  16. ncbi request reprint Fabry disease: a new challenge in endocrinology and metabolism?
    U Feldt-Rasmussen
    Department of Medical Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Eur J Endocrinol 146:741-2. 2002
  17. ncbi request reprint Iodine and cancer
    U Feldt-Rasmussen
    Department of Medical Endocrinology, National University Hospital, Rigshospitalet, Copenhagen University, Denmark
    Thyroid 11:483-6. 2001
    ..The overall incidence for a relationship between iodine and cancer is poor and future studies are warranted...
  18. ncbi request reprint Growth hormone deficiency and replacement in hypopituitary patients previously treated for acromegaly or Cushing's disease
    Ulla Feldt-Rasmussen
    Department of Endocrinology, Rigshospitalet, National University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Eur J Endocrinol 146:67-74. 2002
    ..To study the effects of GH therapy in those patients who had completed at least 6 months of GH replacement...
  19. ncbi request reprint Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults - a KIMS database analysis
    Roger Abs
    Department of Endocrinology, University Hospital, Antwerp, Belgium
    Eur J Endocrinol 155:79-90. 2006
    ..The aim of the present study was to clarify the relationship between GH deficiency (GHD) and some cardiovascular risk factors and to analyse the effect of GH replacement therapy in a large number of patients over a prolonged period of time...
  20. ncbi request reprint High risk of adrenal insufficiency in adults previously treated for idiopathic childhood onset growth hormone deficiency
    Martin Lange
    Department of Endocrinology, Rigshospitalet, DK 2100 Copenhagen, Denmark
    J Clin Endocrinol Metab 88:5784-9. 2003
    ..It is imperative that pituitary axes other than the GH axis are tested at regular intervals, even in the absence of GHD in adulthood...
  21. pmc Selenium supplementation for patients with Graves' hyperthyroidism (the GRASS trial): study protocol for a randomized controlled trial
    Torquil Watt
    Department of Medical Endocrinology, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, Copenhagen DK 2100, Denmark
    Trials 14:119. 2013
    ....
  22. ncbi request reprint Osteopenia: a common aspect of Fabry disease. Predictors of bone mineral density
    Henriette Mersebach
    Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
    Genet Med 9:812-8. 2007
    ..We investigated the bone mineral status in patients with untreated Fabry disease (FD)...
  23. doi request reprint Association of thyroid gland volume, serum insulin-like growth factor-I, and anthropometric variables in euthyroid prepubertal children
    Malene Boas
    University Department of Growth and Reproduction, Rigshospitalet, DK 2100 Copenhagen, Denmark
    J Clin Endocrinol Metab 94:4031-5. 2009
    ..We have investigated thyroid gland volume and several hormonal and anthropometric variables in prepubertal children...
  24. doi request reprint Antithyroid drug-induced fetal goitrous hypothyroidism
    Sofie Bliddal
    Department of Medical Endocrinology, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Nat Rev Endocrinol 7:396-406. 2011
    ..The best way to avoid maternal overtreatment with antithyroid drugs is to monitor closely the maternal thyroid status, especially estimates of free T(4) levels...
  25. ncbi request reprint Abnormal sympathoadrenal activity, but normal energy expenditure in hypopituitarism
    Henriette Mersebach
    Department of Endocrinology, Copenhagen University Hospital, DK 2100 Copenhagen, Denmark
    J Clin Endocrinol Metab 88:5689-95. 2003
    ..This may reflect a central defect in hypopituitarism, however the possible impact of long-term GH and hydrocortisone treatment requires further attention...
  26. doi request reprint Improving a newly developed patient-reported outcome for thyroid patients, using cognitive interviewing
    Torquil Watt
    Department of Endocrinology, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark
    Qual Life Res 17:1009-17. 2008
    ..To improve a newly developed patient-reported outcome measure for thyroid patients using cognitive interviewing...
  27. ncbi request reprint Which domains of thyroid-related quality of life are most relevant? Patients and clinicians provide complementary perspectives
    Torquil Watt
    Department of Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Thyroid 17:647-54. 2007
    ..To identify how thyroid diseases impact the patients' lives and to select the most relevant quality of life (QoL) issues for a thyroid-specific questionnaire...
  28. ncbi request reprint Abnormal bone collagen morphology and decreased bone strength in growth hormone-deficient rats
    Martin Lange
    Department of Endocrinology and Nephrology, Rigshospitalet, Copenhagen, Denmark
    Bone 35:178-85. 2004
    ..Whether similar conditions are present in GHD patients need further investigations. The changes described, however, may provide a co-explanation for the increased fracture rate in GHD...
  29. doi request reprint Narrow intra-individual variation of maternal thyroid function in pregnancy based on a longitudinal study on 132 women
    Malene Boas
    University Department of Growth and Reproduction, GR 5064, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Eur J Endocrinol 161:903-10. 2009
    ....
  30. ncbi request reprint Combined dietary and pharmacological weight management in obese hypopituitary patients
    Henriette Mersebach
    Department of Endocrinology, Copenhagen University Hospital 9, Blegdamsvej DK 2100 Copenhagen, Denmark
    Obes Res 12:1835-43. 2004
    ..In this study, we investigated the combined effect of sibutramine, diet, and exercise in obese hypopituitary patients (HPs)...
  31. doi request reprint Validity and reliability of the novel thyroid-specific quality of life questionnaire, ThyPRO
    Torquil Watt
    Department of Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen Ø, Denmark
    Eur J Endocrinol 162:161-7. 2010
    ..However, before clinical use, clinical validity and test-retest reliability should be evaluated...
  32. ncbi request reprint Quality of life in patients with benign thyroid disorders. A review
    Torquil Watt
    Department of Endocrinology, Copenhagen University Hospital, Rigshospitalet, Denmark
    Eur J Endocrinol 154:501-10. 2006
    ..Studies systematically exploring the relative importance of these various aspects to thyroid patients are lacking, as is a comprehensive, validated thyroid-specific HRQL questionnaire...
  33. ncbi request reprint The impact of idiopathic childhood-onset growth hormone deficiency (GHD) on bone mass in subjects without adult GHD
    Martin Lange
    Department of Endocrinology, Rigshospitalet, Glostrup, Denmark
    Clin Endocrinol (Oxf) 62:18-23. 2005
    ..The aim was to evaluate BMD and bone mineral content (BMC) in adults treated for idiopathic childhood-onset (CO) GHD, 18 years after stopping GH treatment...
  34. ncbi request reprint Thyrotropin-releasing hormone stimulation test in patients with pituitary pathology
    Marie Louise Hartoft-Nielsen
    Department of Endocrinology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
    Horm Res 61:53-7. 2004
    ..To evaluate the value of the thyrotropin-releasing hormone (TRH) stimulation test in the diagnostic work-up of the thyroid function in patients with pituitary pathology...
  35. doi request reprint Graves' disease in two pregnancies complicated by fetal goitrous hypothyroidism: successful in utero treatment with levothyroxine
    Sofie Bliddal
    Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen University, Copenhagen, Denmark
    Thyroid 21:75-81. 2011
    ..Treatment of Graves' disease during pregnancy with antithyroid drugs (ATDs) poses a risk of inducing hypothyroidism and, thus, development of a goiter to the fetus...
  36. doi request reprint GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients
    Simon Doessing
    Department of Orthopaedic Surgery M, Faculty of Health Sciences, Institute of Sports Medicine, Bispebjerg Hospital and Centre for Healthy Aging, University of Copenhagen, Bispebjerg Bakke 23, Copenhagen DK 2400, Denmark
    Eur J Endocrinol 163:853-62. 2010
    ..GH/IGF1 is likely to play an important role in the regulation of tendon and muscle collagen. We hypothesized that the local production of collagen is associated with the level of GH/IGF1...
  37. pmc Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth
    Malene Boas
    Department of Growth and Reproduction, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark
    Environ Health Perspect 118:1458-64. 2010
    ..Phthalates are widely used chemicals, and human exposure is extensive. Recent studies have indicated that phthalates may have thyroid-disrupting properties...
  38. ncbi request reprint Circulating leptin and thyroid dysfunction
    Tina Zimmermann-Belsing
    Department of Endocrinology, University Hospital, Rigshospitalet, Copenhagen, Denmark
    Eur J Endocrinol 149:257-71. 2003
    ..In this review, we have focused on leptin in relation to thyroid pathophysiology...
  39. ncbi request reprint Signs of maternal vascular dysfunction precede preeclampsia in women with type 1 diabetes
    Peter Clausen
    Department of Nephrology and Endocrinology, Copenhagen University Hospital, Rigshospitalet, DK 2100, Copenhagen, Denmark
    J Diabetes Complications 21:288-93. 2007
    ..This study aims to test the hypothesis that vascular dysfunction is present early in pregnancy in women with type 1 diabetes who subsequently develop preeclampsia...
  40. doi request reprint Interleukin-8 production from human somatotroph adenoma cells is stimulated by interleukin-1β and inhibited by growth hormone releasing hormone and somatostatin
    Signe Diness Vindeløv
    Department of Medical Endocrinology, PE 2132, Rigshospitalet, Copenhagen University Hospital, University of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Growth Horm IGF Res 21:134-9. 2011
    ..We investigated the role of cytokines, in particular interleukin (IL)-8, in the pathogenesis of growth hormone (GH) producing tumours...
  41. doi request reprint Few items in the thyroid-related quality of life instrument ThyPRO exhibited differential item functioning
    Torquil Watt
    Department of Endocrinology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark
    Qual Life Res 23:327-38. 2014
    ..To evaluate the extent of differential item functioning (DIF) within the thyroid-specific quality of life patient-reported outcome measure, ThyPRO, according to sex, age, education and thyroid diagnosis...
  42. doi request reprint Thyroid effects of endocrine disrupting chemicals
    Malene Boas
    Department of Growth and Reproduction GR, Rigshospitalet, University of Copenhagen, Denmark
    Mol Cell Endocrinol 355:240-8. 2012
    ....
  43. ncbi request reprint Cardiac effects of low-dose growth hormone replacement therapy in growth hormone-deficient adults. An 18-month randomised, placebo-controlled, double-blind study
    Simone B Sneppen
    Department of Endocrinology, The National University Hospital, Copenhagen, Denmark
    Horm Res 58:21-9. 2002
    ..To characterise the effect of long-term low-dose growth hormone (GH) treatment on cardiac anatomy and function...
  44. ncbi request reprint Unsuccessful radioiodine treatment of a non-toxic goiter: a case report
    Marie Louise Hartoft-Nielsen
    Department of Medical Endocrinology, Rigshospitalet, University Hospital of Copenhagen, Denmark
    Basic Clin Pharmacol Toxicol 95:72-5. 2004
    ..However, this reported case should not discredit the use of radioiodine treatment of non-toxic goiters, but focus on patients with a single large solitary adenoma in whom this treatment may be inappropriate...
  45. pmc Escitalopram and neuroendocrine response in healthy first-degree relatives to depressed patients--a randomized placebo-controlled trial
    Ulla Knorr
    Department of Psychiatry Copenhagen, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    PLoS ONE 6:e21224. 2011
    ....
  46. doi request reprint Hypopituitarism is uncommon after aneurysmal subarachnoid haemorrhage
    Marianne Klose
    Department of Medical Endocrinology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark
    Clin Endocrinol (Oxf) 73:95-101. 2010
    ..We aimed at estimating the risk of hypopituitarism after SAH using strict criteria including confirmatory testing in case of suggested insufficiency...
  47. pmc Do Thyroid Disrupting Chemicals Influence Foetal Development during Pregnancy?
    Marie Louise Hartoft-Nielsen
    Department of Medical Endocrinology PE 2131, Rigshospitalet, University Hospital of Copenhagen, 2100 Copenhagen, Denmark
    J Thyroid Res 2011:342189. 2011
    ..Knowledge of the effects is expected to impact the general debate on the use of these chemicals. However, more studies are needed to elucidate the issue, since human studies are scarce...
  48. ncbi request reprint Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnancies
    Pia Ekbom
    The Endocrine Clinic, 2The Obstetric Clinic, The National University Hospital, DK 2100 Copenhagen, Denmark
    Acta Obstet Gynecol Scand 85:143-7. 2006
    ..The aim was to investigate whether activin A and inhibin A in serum were elevated in type I diabetic women after developing pre-eclampsia and, if so, were they clinically useful as predictors of pre-eclampsia...
  49. doi request reprint Gestational age-specific reference ranges from different laboratories misclassify pregnant women's thyroid status: comparison of two longitudinal prospective cohort studies
    Sofie Bliddal
    Department of Endocrinology, Section 2132, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Eur J Endocrinol 170:329-39. 2014
    ..Pregnancy-related changes in maternal thyroid status necessitate the use of gestational age-specific reference ranges. In this study, we investigated between-laboratory reproducibility of thyroid reference ranges in pregnant women...
  50. ncbi request reprint An audit of the insulin-tolerance test in 255 patients with pituitary disease
    Martin Lange
    Department of Endocrinology, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Eur J Endocrinol 147:41-7. 2002
    ..The aim of this study was to determine factors that may influence nadir blood glucose (BG) when using a mean insulin dose of 0.1 IU/kg body weight. Furthermore, we wanted to evaluate the safety and GH-related aspects of the ITT...
  51. ncbi request reprint Ultrasonically measured horizontal eye muscle thickness in thyroid associated orbitopathy: cross-sectional and longitudinal aspects in a Danish series
    Hans C Fledelius
    Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Denmark
    Acta Ophthalmol Scand 81:143-50. 2003
    ..To analyse horizontal extraocular muscle findings by ultrasound and exophthalmometry in a tertiary endocrinology centre series of patients with thyroid associated orbitopathy (TAO)...
  52. ncbi request reprint Pegvisomant treatment in a 4-year-old girl with neurofibromatosis type 1
    Katharina M Main
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Horm Res 65:1-5. 2006
    ..Recently, a GH receptor antagonist, pegvisomant, was introduced for the treatment of adults with acromegaly. We wanted to investigate whether pegvisomant was effective in a child with octreotide-resistant GH excess...
  53. doi request reprint Is increase in bone mineral content caused by increase in skeletal muscle mass/strength in adult patients with GH-treated GH deficiency? A systematic literature analysis
    Oliver Klefter
    Department of Medical Endocrinology, PE 2131, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Eur J Endocrinol 161:213-21. 2009
    ....
  54. ncbi request reprint [Measurement of health-related quality of life in thyroid patients]
    Torquil Watt
    Odense Universitetshospital
    Ugeskr Laeger 170:850-2. 2008
    ..This may be due to the lack of a valid HRQL measurement. Hopefully, increased focus on HRQL and the development of a valid thyroid-specific HRQL measure will improve this status...
  55. doi request reprint Prevalence of posttraumatic growth hormone deficiency is highly dependent on the diagnostic set-up: results from The Danish National Study on Posttraumatic Hypopituitarism
    Marianne Klose
    Department of Medical Endocrinology M K, U F R, Copenhagen University Hospital, Rigshospitalet, DK 2100 Copenhagen, Denmark Department of Internal Medicine and Endocrinology K S, J J, J F, J S C, Aarhus University Hospital, DK 8000 Aarhus, Denmark Department of Medical Endocrinology L L C, M A, Odense University Hospital, DK 5000 Odense, Denmark and Department of Medical Endocrinology P L, Aalborg University Hospital, DK 9100 Aalborg, Denmark
    J Clin Endocrinol Metab 99:101-10. 2014
    ..Predominantly isolated GH deficiency (GHD) was reported in the literature, raising the question of potential methodological bias...
  56. doi request reprint Why glucocorticoid withdrawal may sometimes be as dangerous as the treatment itself
    Stina Dinsen
    Department of Medical Endocrinology, Rigshospitalet, Copenhagen University Hospital, DK 2100 Copenhagen, Denmark
    Eur J Intern Med 24:714-20. 2013
    ..Further awareness of the potential side effect of withdrawal of glucocorticoid and further research are urgently needed. ..
  57. doi request reprint Establishing construct validity for the thyroid-specific patient reported outcome measure (ThyPRO): an initial examination
    Torquil Watt
    Department of Endocrinology, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark
    Qual Life Res 18:483-96. 2009
    ..To establish a reliable and valid scale structure of a patient-reported outcome measuring thyroid-specific quality of life...
  58. doi request reprint Iodine and tri-iodo-thyronine reduce the incidence of type 1 diabetes mellitus in the autoimmune prone BB rats
    Marie Louise Hartoft-Nielsen
    Department of Endocrinology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
    Autoimmunity 42:131-8. 2009
    ..In Wistar rats T3 treatment increased the beta cell mass per bodyweight. The modulation of thyroid function during postnatal development may thus affect the precipitation of T1DM in genetically susceptible individuals...
  59. pmc Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    J Thyroid Res 2011:598712. 2011
    ..Measurement of antithyroperoxidase and/or TSH receptor antibodies adds to the differential diagnosis of autoimmune and nonautoimmune thyroid diseases...
  60. doi request reprint Bridging provocative tests and clinical manifestations of growth hormone deficiency in adults
    Ulla Feldt-Rasmussen
    Department of Medical Endocrinology, National University Hospital, Copenhagen, Denmark
    Horm Res 68:57-8. 2007
  61. doi request reprint Fabry disease mimicking hypertrophic cardiomyopathy: genetic screening needed for establishing the diagnosis in women
    Ole Havndrup
    Department of Cardiology, Heart Centre, The National University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Eur J Heart Fail 12:535-40. 2010
    ..The 'cardiac variant' of Fabry disease which only affects the heart may be missed unless specifically tested for...
  62. ncbi request reprint Growth hormone and body composition
    Henriette Mersebach
    Department of Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
    Front Horm Res 33:185-95. 2005
  63. doi request reprint Elevated third-trimester haemoglobin A 1c predicts preterm delivery in type 1 diabetes
    Pia Ekbom
    Endocrine Clinic, The National University Hospital, Rigshospitalet, Copenhagen, Denmark
    J Diabetes Complications 22:297-302. 2008
    ..The adjusted odds ratio per 1% increment in HbA(1c) at 28 weeks of gestation was 2.8 (95% CI 1.7-4.4). HbA(1c) at 28 weeks of gestation was a clinical significant predictor of preterm delivery in type 1 diabetes...
  64. doi request reprint Agalsidase beta treatment is associated with improved quality of life in patients with Fabry disease: findings from the Fabry Registry
    Torquil Watt
    Department of Endocrinology, National University Hospital, Copenhagen, Denmark
    Genet Med 12:703-12. 2010
    ..To evaluate the effect of agalsidase beta on longitudinal health-related quality of life in patients with Fabry disease...
  65. ncbi request reprint Bone mineral content and bone metabolism during physiological GH treatment in GH-deficient adults--an 18-month randomised, placebo-controlled, double blinded trial
    Simone Bjerregård Sneppen
    Department of Endocrinology, National University Hospital, Copenhagen, Denmark
    Eur J Endocrinol 146:187-95. 2002
    ..To evaluate the effect of physiological adult growth hormone (GH) replacement on bones...
  66. pmc Rationale and design of the participant, investigator, observer, and data-analyst-blinded randomized AGENDA trial on associations between gene-polymorphisms, endophenotypes for depression and antidepressive intervention: the effect of escitalopram versus
    Ulla Knorr
    Department of Psychiatry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Trials 10:66. 2009
    ..The primary outcome measure is the change in plasma cortisol in the dexamethasone-corticotrophin releasing hormone test from baseline to the end of intervention...
  67. doi request reprint Environmental chemicals and thyroid function: an update
    Malene Boas
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Curr Opin Endocrinol Diabetes Obes 16:385-91. 2009
    ..To overview the effects of endocrine disrupters on thyroid function...
  68. ncbi request reprint Characteristics of the Danish families with multiple endocrine neoplasia type 1
    Anne Charlotte Jäger
    Department of Clinical Biochemistry, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Mol Cell Endocrinol 249:123-32. 2006
    ..In contrast, sporadic carcinoid tumours or primary prolactinomas are rarely associated with germ-line MEN1 mutations...
  69. ncbi request reprint Increased risk of osteoporotic fractures in patients with Cushing's syndrome
    Peter Vestergaard
    The Osteoporosis Clinic, Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Tage Hansens Gade 2, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 146:51-6. 2002
    ..To evaluate if fracture risk was increased in patients with Cushing's syndrome due to the increased endogenous cortisol production...
  70. ncbi request reprint Incidence of GH deficiency - a nationwide study
    Kirstine Stochholm
    Medical Department M Endocrinology and Diabetes, Aarhus Sygehus, NBG, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 155:61-71. 2006
    ..Data on incidence rates are scarce in GH deficiency (GHD). Here, we estimate the incidence rate in childhood onset (CO) and adult onset (AO) GHD in Denmark...
  71. ncbi request reprint Mortality and GH deficiency: a nationwide study
    Kirstine Stochholm
    Medical Department M Endocrinology and Diabetes, Aarhus University Hospital, Aarhus Sygehus, NBG, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 157:9-18. 2007
    ..To estimate the mortality in Denmark in patients suffering from GH deficiency (GHD)...
  72. ncbi request reprint Effect of growth hormone replacement therapy on pituitary hormone secretion and hormone replacement therapies in GHD adults
    Erika Hubina
    Department of Medicine, National Medical Center, Budapest, Hungary
    Horm Res 61:211-7. 2004
    ....
  73. ncbi request reprint Obesity: the new worldwide epidemic threat to general health and our complete lack of effective treatment
    Tina Zimmermann-Belsing
    Endocrinology 145:1501-2. 2004
  74. ncbi request reprint Clinical implications of residual growth hormone (GH) response to provocative testing in adults with severe GH deficiency
    Georg Brabant
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Manchester M20 4BX, United Kingdom
    J Clin Endocrinol Metab 92:2604-9. 2007
    ..It is unknown whether the amount of residual GH reserve under the cutoff value has any physiological implication...
  75. ncbi request reprint Females with Fabry disease frequently have major organ involvement: lessons from the Fabry Registry
    William R Wilcox
    Medical Genetics Institute, Cedars Sinai Medical Center, 8700 Beverly Blvd SSB, Los Angeles, CA 90048, USA
    Mol Genet Metab 93:112-28. 2008
    ..Thus, females with FD have a significant risk for major organ involvement and decreased QoL. Females should be regularly monitored for signs and symptoms of FD, and considered for enzyme replacement therapy...
  76. ncbi request reprint Discontinuation of estrogen replacement therapy in GH-treated hypopituitary women alters androgen status and IGF-I
    Jens Juel Christiansen
    Medical Department M, Arhus Sygehus, Arhus University Hospital, Nørrebrogade 44, DK 8000 Arhus C, Denmark
    Eur J Endocrinol 152:719-26. 2005
    ..Twenty six patients were studied twice: with estrogen replacement and after 28 days of estrogen discontinuation in a randomised design...
  77. ncbi request reprint Cotreatment of acromegaly with a somatostatin analog and a growth hormone receptor antagonist
    Jens Otto Lunde Jørgensen
    Medical Department M, Aarhus University Hospital, Norrebrogade 44, DK 8000 C Aarhus, Denmark
    J Clin Endocrinol Metab 90:5627-31. 2005
    ..Pegvisomant is a GH receptor antagonist that blocks the peripheral actions of GH in acromegaly. Pegvisomant, in contrast to somatostatin (SMS) analogs, does not suppress the activity of the GH-producing adenoma...
  78. ncbi request reprint Isolated growth hormone (GH) deficiency in adult patients: baseline clinical characteristics and responses to GH replacement in comparison with hypopituitary patients. A sub-analysis of the KIMS database
    Roger Abs
    Department of Endocrinology, University Hospital Antwerp, Wilrijkstraat 10, B 2650 Edegem, Belgium
    Growth Horm IGF Res 15:349-59. 2005
    ....
  79. doi request reprint Morbidity and GH deficiency: a nationwide study
    Kirstine Stochholm
    Medical Department M Endocrinology and Diabetes, Aarhus University Hospital, Aarhus Sygehus, NBG, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 158:447-57. 2008
    ..To estimate morbidity in Denmark in all patients with GH deficiency (GHD)...
  80. doi request reprint Thyroid autoantibodies and thyroid function in subjects exposed to Chernobyl fallout during childhood: evidence for a transient radiation-induced elevation of serum thyroid antibodies without an increase in thyroid autoimmune disease
    Laura Agate
    Department of Endocrinology, University of Pisa, Via Paradisa 2, Pisa, Italy
    J Clin Endocrinol Metab 93:2729-36. 2008
    ..An increase in the prevalence of thyroid autoantibodies (ATAs) was reported 6-8 yr after the Chernobyl accident in radiation-exposed children and adolescents...
  81. ncbi request reprint Environmental chemicals and thyroid function
    Malene Boas
    University Department of Growth and Reproduction GR 5064, Copenhagen Denmark
    Eur J Endocrinol 154:599-611. 2006
    ..It is therefore urgent to clarify whether the animal data showing effects of chemicals on thyroid function can be extended to humans...
  82. ncbi request reprint Small-fibre neuropathy in female Fabry patients: reduced allodynia and skin blood flow after topical capsaicin
    Anette T Moller
    Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    J Peripher Nerv Syst 11:119-25. 2006
    ..006) in female Fabry patients. This indicates that female Fabry patients have a significant loss of small-fibre function and demonstrates that it is possible to evaluate this by a non-invasive method...
  83. ncbi request reprint Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid disease
    Zubair Baloch
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, USA
    Thyroid 13:3-126. 2003
  84. ncbi request reprint Distribution of alpha-galactosidase A in normal human kidney and renal accumulation and distribution of recombinant alpha-galactosidase A in Fabry mice
    Erik I Christensen
    Department of Cell Biology, Institute of Anatomy, Wilh Meyers Alle, Building 234, University of Aarhus, DK 8000 Aarhus C, Denmark
    J Am Soc Nephrol 18:698-706. 2007
    ....