Research Topics
| Louise BochsenSummaryAffiliation: Copenhagen University Hospital Country: Denmark Publications
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Detail Information
Publications
Higher Thrombelastograph platelet reactivity in cardiac surgery patients than in blood donorsLouise Bochsen
Department of Clinical Immunology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Scand Cardiovasc J 41:321-4. 2007..The aim of this study was to investigate the platelet hyperreactivity and the variability in platelet reactivity due to ADP in cardiac surgery patients and donors...
The influence of platelets, plasma and red blood cells on functional haemostatic assaysLouise Bochsen
Section for Transfusion Medicine, Capital Region Blood Bank, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Blood Coagul Fibrinolysis 22:167-75. 2011..The results emphasize that the concentrations of all cellular and plasmatic components in whole blood should be taken into account when interpreting results obtained by TEG and multiplate...- Platelet hyperreactivity in response to on- and off-pump coronary artery bypass graftingLouise Bochsen
Department of Clinical Immunology 2032, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
J Extra Corpor Technol 41:15-9. 2009..These results suggest that a more aggressive antithrombotic treatment might be warranted for patients undergoing coronary artery bypass grafting, both OPCAB and CABG, presenting with a high MA pre- and postsurgery... - Hemostatic function of buffy coat platelets in additive solution treated with pathogen reduction technologySisse R Ostrowski
Section for Transfusion Medicine, Capital Region Blood Bank, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Transfusion 51:344-56. 2011..To investigate this, buffy coat PLTs (BCPs) stored in PLT additive solution (SSP+) with or without Mirasol PRT treatment (CaridianBCT Biotechnologies) were compared by functional hemostatic assays... - The in vitro effect of recombinant factor VIIa on coated platelet formation and clot dynamics of stored platelet concentratesMette S Svendsen
Blood Bank, Department of Clinical Immunology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
Transfusion 49:2186-94. 2009..We investigated whether activated recombinant factor VII (rFVIIa, NovoSeven, Novo Nordisk A/S) could improve the ability of stored PLTs to support coagulation under conditions that promote the formation of coated PLTs... - The influence of low platelet count on whole blood aggregometry assessed by MultiplateTrine Stissing
Department of Clinical Immunology, Section for Transfusion Medicine, Capital Region Blood Bank, Rigshospitalet 2034, University of Copenhagen, Denmark
Clin Appl Thromb Hemost 17:E211-7. 2011..In conclusion, platelet concentration of <150 × 10(9)/L may influence Multiplate which should be considered in clinical settings. Furthermore, the findings emphasize the importance of evaluating haemostasis in its natural matrix, WB... - Investigation of the effect of kaolin and tissue-factor-activated citrated whole blood, on clot-forming variables, as evaluated by thromboelastographyPär I Johansson
Department of Clinical Immunology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Transfusion 48:2377-83. 2008..Implementing TEG as a routine laboratory-based analysis, however, requires validation of the activators employed and the effect of storage of the WB sample in citrate before analysis... 
Thrombelastography and tromboelastometry in assessing coagulopathy in traumaPär I Johansson
Regional Blood Bank, Rigshospitalet, University of Copenhagen, Denmark
Scand J Trauma Resusc Emerg Med 17:45. 2009....- In vitro cell quality of buffy coat platelets in additive solution treated with pathogen reduction technologySisse R Ostrowski
Section for Transfusion Medicine, Capital Region Blood Bank, Department of Clinical Immunology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Transfusion 50:2210-9. 2010..To investigate this, buffy coat PLTs (BCPs) in PLT additive solution (AS; SSP+) with or without Mirasol PRT (CaridianBCT Biotechnologies) were assessed by quality control tests and four-color flow cytometry... - Hypercoagulability and platelet inhibition after OPCAB. Randomized intervention with clopidogrelAllan Bybeck Nielsen
Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen University Hospital, Denmark
Scand Cardiovasc J 41:325-30. 2007..However, hypercoagulability following OPCAB is still of concern, and acetylsalicylic acid as thromboembolic prophylaxis might be insufficient in the first weeks following OPCAB surgery... - Transfusion packages for massively bleeding patients: the effect on clot formation and stability as evaluated by Thrombelastograph (TEG)Pär I Johansson
Transfusion Service, Department of Clinical Immunology, University of Copenhagen, Rigshospitalet 2034, Blegdamsvej 9, Copenhagen, Denmark
Transfus Apher Sci 39:3-8. 2008..01). In 8 patients damage control surgery was successful and 6 of these patients survived. The result indicates that an early balanced transfusion strategy maintains haemostatic competence in massively bleeding patients... - Effects of nucleotides and nucleosides on coagulationLaurids T Bune
Copenhagen Muscle Research Centre, Rigshospitalet, Denmark
Blood Coagul Fibrinolysis 21:436-41. 2010..The potential clinical significance of these findings should be investigated further because ADP discharged systemically may possibly contribute to the coagulopathy observed in severe sepsis...