H Bisgaard

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. ncbi request reprint Automatic actuation of a dry powder inhaler into a nonelectrostatic spacer
    H Bisgaard
    Pulmonary Service, Department of Pediatrics, Rigshospitalet, National University Hospital, Copenhagen, Denmark
    Am J Respir Crit Care Med 157:518-21. 1998
  2. ncbi request reprint Pathophysiology of the cysteinyl leukotrienes and effects of leukotriene receptor antagonists in asthma
    H Bisgaard
    Department of Paediatrics, University Hospital of Copenhagen, Cophenhagen, Denmark
    Allergy 56:7-11. 2001
  3. ncbi request reprint Role of leukotrienes in asthma pathophysiology
    H Bisgaard
    Department of Pediatrics, National University Hospital, Rigshospitalet, Copenhagen, Denmark
    Pediatr Pulmonol 30:166-76. 2000
  4. ncbi request reprint Bronchoprotection with a leukotriene receptor antagonist in asthmatic preschool children
    H Bisgaard
    Department of Pediatrics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Am J Respir Crit Care Med 162:187-90. 2000
  5. ncbi request reprint Long-acting beta(2)-agonists in management of childhood asthma: A critical review of the literature
    H Bisgaard
    Department of Pediatrics, National University Hospital, Rigshospitalet, Copenhagen, Denmark
    Pediatr Pulmonol 29:221-34. 2000
  6. ncbi request reprint NO in exhaled air of asthmatic children is reduced by the leukotriene receptor antagonist montelukast
    H Bisgaard
    Department of Paediatrics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Am J Respir Crit Care Med 160:1227-31. 1999
  7. ncbi request reprint Future options for aerosol delivery to children
    H Bisgaard
    Department of Paediatrics, National University Hospital, Copenhagen, Denmark
    Allergy 54:97-103. 1999
  8. ncbi request reprint The effect of inhaled fluticasone propionate in the treatment of young asthmatic children: a dose comparison study
    H Bisgaard
    Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Am J Respir Crit Care Med 160:126-31. 1999
  9. ncbi request reprint Bronchodilation and bronchoprotection in asthmatic preschool children from formoterol administered by mechanically actuated dry-powder inhaler and spacer
    K G Nielsen
    Department of Pediatrics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Am J Respir Crit Care Med 164:256-9. 2001
  10. ncbi request reprint Heterogeneity of FeNO response to inhaled steroid in asthmatic children
    F Buchvald
    Department of Paediatrics, Rigshospitalet, National University Hospital, Copenhagen, Denmark
    Clin Exp Allergy 33:1735-40. 2003

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Automatic actuation of a dry powder inhaler into a nonelectrostatic spacer
    H Bisgaard
    Pulmonary Service, Department of Pediatrics, Rigshospitalet, National University Hospital, Copenhagen, Denmark
    Am J Respir Crit Care Med 157:518-21. 1998
    ..These features should prove advantageous in the treatment of young children with inhaled medication...
  2. ncbi request reprint Pathophysiology of the cysteinyl leukotrienes and effects of leukotriene receptor antagonists in asthma
    H Bisgaard
    Department of Paediatrics, University Hospital of Copenhagen, Cophenhagen, Denmark
    Allergy 56:7-11. 2001
    ..Moreover, the bronchodilator properties of the leukotriene receptor antagonists are additive with those of beta agonists. These data provide strong support for the use of leukotriene receptor antagonists for treating asthma...
  3. ncbi request reprint Role of leukotrienes in asthma pathophysiology
    H Bisgaard
    Department of Pediatrics, National University Hospital, Rigshospitalet, Copenhagen, Denmark
    Pediatr Pulmonol 30:166-76. 2000
    ..The bronchodilator properties of CysLTRAs seem to be additive to those of beta(2)-agonists and corticosteroids. These data suggest that CysLTs are important therapeutic targets in the management of inflammation in asthma...
  4. ncbi request reprint Bronchoprotection with a leukotriene receptor antagonist in asthmatic preschool children
    H Bisgaard
    Department of Pediatrics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Am J Respir Crit Care Med 162:187-90. 2000
    ..The bronchoprotection appeared to be homogeneous among the children, and seemed independent of steroid treatment. This suggests that LTRAs may be of therapeutic use in limiting clinical symptoms of asthma in young children...
  5. ncbi request reprint Long-acting beta(2)-agonists in management of childhood asthma: A critical review of the literature
    H Bisgaard
    Department of Pediatrics, National University Hospital, Rigshospitalet, Copenhagen, Denmark
    Pediatr Pulmonol 29:221-34. 2000
    ..Future studies should examine the positioning of long-acting beta(2)-agonists as an "as needed" rescue medication instead of short-acting beta(2)-agonists for pediatric asthma management...
  6. ncbi request reprint NO in exhaled air of asthmatic children is reduced by the leukotriene receptor antagonist montelukast
    H Bisgaard
    Department of Paediatrics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Am J Respir Crit Care Med 160:1227-31. 1999
    ..In conclusion, FENO in asthmatic children was significantly decreased from montelukast, which corroborates anti- inflammatory properties of LTRA...
  7. ncbi request reprint Future options for aerosol delivery to children
    H Bisgaard
    Department of Paediatrics, National University Hospital, Copenhagen, Denmark
    Allergy 54:97-103. 1999
    ..The spacer is equipped with a face mask that prevents nasal breathing. Such features should improve our ability to treat young children with inhaled drug aerosols...
  8. ncbi request reprint The effect of inhaled fluticasone propionate in the treatment of young asthmatic children: a dose comparison study
    H Bisgaard
    Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Am J Respir Crit Care Med 160:126-31. 1999
    ..Asthmatic symptoms in 1- to 3-yr-old children responded in a significant and dose-related manner to treatment with FP within a pediatric dose range...
  9. ncbi request reprint Bronchodilation and bronchoprotection in asthmatic preschool children from formoterol administered by mechanically actuated dry-powder inhaler and spacer
    K G Nielsen
    Department of Pediatrics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Am J Respir Crit Care Med 164:256-9. 2001
    ..Furthermore, this study suggests that mechanical actuation of DPI using a spacer is effective for aerosol treatment of young asthmatic children...
  10. ncbi request reprint Heterogeneity of FeNO response to inhaled steroid in asthmatic children
    F Buchvald
    Department of Paediatrics, Rigshospitalet, National University Hospital, Copenhagen, Denmark
    Clin Exp Allergy 33:1735-40. 2003
    ..Nitric oxide in exhaled air is regarded as an inflammation marker, and may be used to monitor the anti-inflammatory control from inhaled corticosteroids (ICSs). However, this response to ICSs exhibits a heterogeneous pattern...
  11. ncbi request reprint Discriminative capacity of bronchodilator response measured with three different lung function techniques in asthmatic and healthy children aged 2 to 5 years
    K G Nielsen
    Department of Pediatrics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Am J Respir Crit Care Med 164:554-9. 2001
    ..This may help define asthma in this clinically difficult-to-manage group of young wheezy children. The sensitivity and specificity of the other methods used in the study were less than those of sRaw...
  12. ncbi request reprint Leukotriene modifiers in pediatric asthma management
    H Bisgaard
    Department of Paediatrics, Copenhagen University Hospital, Copenhagen, Denmark
    Pediatrics 107:381-90. 2001
    ..Given their efficacy, antiinflammatory activity, oral administration, and safety, LT modifiers will play an important role in the treatment of asthmatic children...
  13. ncbi request reprint Cost-effectiveness of fluticasone propionate administered via metered-dose inhaler plus babyhaler spacer in the treatment of asthma in preschool-aged children
    H Bisgaard
    Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Chest 120:1835-42. 2001
    ..To evaluate the cost-effectiveness of inhaled fluticasone propionate (FP) in children aged 12 to 47 months with asthma symptoms...
  14. doi request reprint Allergic rhinitis is associated with otitis media with effusion: a birth cohort study
    E Kreiner-Møller
    COPSAC, The Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    Clin Exp Allergy 42:1615-20. 2012
    ..Childhood otitis media with effusion is a common disease and a link to allergic diseases has been suggested...
  15. ncbi request reprint Determinants of lung function and airway hyperresponsiveness in asthmatic children
    H Bisgaard
    Danish Paediatric Asthma Center, Copenhagen University Hospital, Gentofte, DK 2900 Copenhagen, Denmark
    Respir Med 101:1477-82. 2007
    ..This cross-sectional study aimed to elucidate factors contributing to such decline and the possible modifying effect of steroid treatment...
  16. doi request reprint Deep phenotyping of the unselected COPSAC2010 birth cohort study
    H Bisgaard
    Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital, Gentofte and Naestved, Denmark Health Sciences, University of Copenhagen, Copenhagen, Denmark
    Clin Exp Allergy 43:1384-94. 2013
    ....
  17. doi request reprint Cord blood Th2-related chemokine CCL22 levels associate with elevated total-IgE during preschool age
    N V Følsgaard
    Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital, Gentofte, Denmark
    Clin Exp Allergy 42:1596-603. 2012
    ..Early-life immune deviation is suspected in the inception of atopic disease...
  18. ncbi request reprint FeNO measured at fixed exhalation flow rate during controlled tidal breathing in children from the age of 2 yr
    F Buchvald
    Department of Paediatrics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Am J Respir Crit Care Med 163:699-704. 2001
    ..FeNO(controlled) covaries with asthma disease severity and steroid dose. FeNO(controlled) is therefore suggested as a noninvasive diagnostic tool for monitoring asthma disease activity in young children with asthma from the age of 2 yr...
  19. doi request reprint Neonatal size in term children is associated with asthma at age 7, but not with atopic dermatitis or allergic sensitization
    A Sevelsted
    Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen, Gentofte, Copenhagen, Denmark
    Allergy 67:670-5. 2012
    ..We hypothesized that anthropometrics in the newborn is associated with development of asthma later in life...
  20. doi request reprint VEGFA variants are associated with pre-school lung function, but not neonatal lung function
    E Kreiner-Møller
    COPSAC COpenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital, Gentofte, Denmark The Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark
    Clin Exp Allergy 43:1236-45. 2013
    ..We studied VEGFA gene variants and plasma levels and the development of lung function, bronchial hyperresponsiveness and asthma in childhood...
  21. ncbi request reprint Biomarkers of exposure to environmental tobacco smoke in infants
    M Sørensen
    Institute of Public Health, University of Copenhagen, Copenhagen, Denmark
    Biomarkers 12:38-46. 2007
    ..In conclusion, nicotine in hair appears to be the biomarker most strongly associated with parental reports on exposure to ETS in infants...
  22. doi request reprint Objective assessments of allergic and nonallergic rhinitis in young children
    B L K Chawes
    Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte Copenhagen, Denmark
    Allergy 64:1547-53. 2009
    ..Allergic and nonallergic rhinitis are common childhood disorders...
  23. ncbi request reprint Efficacy of steroid treatments in the asthmatic preschool child
    H Bisgaard
    Department of Paediatrics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Allergy 57:32-41. 2002
    ..Asthma represents the most common chronic disease in preschool children. Hospital admission for wheezy disorders is the most common paediatric chronic disease causing hospital admission and more common in young children than later in life...