L B Tanko

Summary

Affiliation: Center for Clinical and Basic Research
Country: Denmark

Publications

  1. ncbi request reprint The clinical potential of estrogen for the prevention of osteoarthritis: what is known and what needs to be done?
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup Byvej 222, 2750 Ballerup, Denmark
    Womens Health (Lond Engl) 1:125-32. 2005
  2. ncbi request reprint An update on the antiestrogenic effect of smoking: a literature review with implications for researchers and practitioners
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    Menopause 11:104-9. 2004
  3. ncbi request reprint Effective doses of ibandronate do not influence the 3-year progression of aortic calcification in elderly osteoporotic women
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    Osteoporos Int 16:184-90. 2005
  4. ncbi request reprint Safety and efficacy of a novel salmon calcitonin (sCT) technology-based oral formulation in healthy postmenopausal women: acute and 3-month effects on biomarkers of bone turnover
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    J Bone Miner Res 19:1531-8. 2004
  5. ncbi request reprint Novel associations between bioavailable estradiol and adipokines in elderly women with different phenotypes of obesity: implications for atherogenesis
    Laszlo B Tanko
    Prospective Epidemiological Risk Factor PERF study group, Center for Clinical and Basic Research, Ballerup Byvej 222, 2750 Ballerup, Ballerup, Denmark
    Circulation 110:2246-52. 2004
  6. ncbi request reprint Enlarged waist combined with elevated triglycerides is a strong predictor of accelerated atherogenesis and related cardiovascular mortality in postmenopausal women
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup Byvej 222, 2750 Ballerup, Denmark
    Circulation 111:1883-90. 2005
  7. ncbi request reprint [Central fat deposits contribute to atherosclerosis and insulin resistance and peripheral fat deposits protect against atherosclerosis and insulin resistance in postmenopausal women--secondary publication]
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup
    Ugeskr Laeger 167:3597-601. 2005
  8. ncbi request reprint Relationship between osteoporosis and cardiovascular disease in postmenopausal women
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    J Bone Miner Res 20:1912-20. 2005
  9. ncbi request reprint Effects of 17beta-oestradiol plus different doses of drospirenone on adipose tissue, adiponectin and atherogenic metabolites in postmenopausal women
    L B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    J Intern Med 258:544-53. 2005
  10. ncbi request reprint ACDC/adiponectin and PPAR-gamma gene polymorphisms: implications for features of obesity
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    Obes Res 13:2113-21. 2005

Detail Information

Publications31

  1. ncbi request reprint The clinical potential of estrogen for the prevention of osteoarthritis: what is known and what needs to be done?
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup Byvej 222, 2750 Ballerup, Denmark
    Womens Health (Lond Engl) 1:125-32. 2005
    ....
  2. ncbi request reprint An update on the antiestrogenic effect of smoking: a literature review with implications for researchers and practitioners
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    Menopause 11:104-9. 2004
    ..DESIGN Summary of own research and a MEDLINE search of English-language literature on the antiestrogenic effect of smoking in pre- and postmenopausal women published during the past two decades...
  3. ncbi request reprint Effective doses of ibandronate do not influence the 3-year progression of aortic calcification in elderly osteoporotic women
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    Osteoporos Int 16:184-90. 2005
    ..These findings thus suggest that 3-year treatment with effective doses of ibandronate does not pose any cardiovascular risk in terms of altering vascular calcification...
  4. ncbi request reprint Safety and efficacy of a novel salmon calcitonin (sCT) technology-based oral formulation in healthy postmenopausal women: acute and 3-month effects on biomarkers of bone turnover
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    J Bone Miner Res 19:1531-8. 2004
    ..The results show (1) effective enteral absorption, (2) marked inhibition of bone resorption with minimal alteration of formation, and (3) reproducibility of responses over 3 months...
  5. ncbi request reprint Novel associations between bioavailable estradiol and adipokines in elderly women with different phenotypes of obesity: implications for atherogenesis
    Laszlo B Tanko
    Prospective Epidemiological Risk Factor PERF study group, Center for Clinical and Basic Research, Ballerup Byvej 222, 2750 Ballerup, Ballerup, Denmark
    Circulation 110:2246-52. 2004
    ..Peripheral adiposity confers protection against diabetes and atherosclerosis in elderly women. The underlying mechanisms, however, remain to be elucidated...
  6. ncbi request reprint Enlarged waist combined with elevated triglycerides is a strong predictor of accelerated atherogenesis and related cardiovascular mortality in postmenopausal women
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup Byvej 222, 2750 Ballerup, Denmark
    Circulation 111:1883-90. 2005
    ..Whether EWET offers superior disease and event prediction in postmenopausal women, however, remains unknown...
  7. ncbi request reprint [Central fat deposits contribute to atherosclerosis and insulin resistance and peripheral fat deposits protect against atherosclerosis and insulin resistance in postmenopausal women--secondary publication]
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup
    Ugeskr Laeger 167:3597-601. 2005
    ..In postmenopausal women, body fat distribution has more critical implications for metabolic and cardiovascular risk than overall obesity per se...
  8. ncbi request reprint Relationship between osteoporosis and cardiovascular disease in postmenopausal women
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    J Bone Miner Res 20:1912-20. 2005
    ..Accordingly, treatment of postmenopausal osteoporosis should include consideration of measures to prevent adverse cardiovascular outcomes...
  9. ncbi request reprint Effects of 17beta-oestradiol plus different doses of drospirenone on adipose tissue, adiponectin and atherogenic metabolites in postmenopausal women
    L B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    J Intern Med 258:544-53. 2005
    ..To investigate how variation in the dose of the progestogen influence the impact of 17beta-oestradiol plus drospirenone (DRSP) treatment on adipose tissue and its secretor function with direct implications for atherogenic metabolites...
  10. ncbi request reprint ACDC/adiponectin and PPAR-gamma gene polymorphisms: implications for features of obesity
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    Obes Res 13:2113-21. 2005
    ....
  11. ncbi request reprint Biochemical approach to the detection and monitoring of metastatic bone disease: What do we know and what questions need answers?
    Laszlo B Tanko
    Center for Clinical and Basic Research A S, Ballerup Byvej 222, 2750, Ballerup, Denmark
    Cancer Metastasis Rev 25:659-68. 2006
    ....
  12. ncbi request reprint Low bone mineral density in the hip as a marker of advanced atherosclerosis in elderly women
    L B Tanko
    Center for Clinical and Basic Research A S, Aalborg, Denmark
    Calcif Tissue Int 73:15-20. 2003
    ..The results further emphasize that osteoporosis in the hip and peripheral vascular disease are linked by common risk factors and pathomechanisms...
  13. ncbi request reprint Central and peripheral fat mass have contrasting effect on the progression of aortic calcification in postmenopausal women
    Laszlo B Tanko
    Center for Clinical and Basic Research A S, Ballerup, Denmark
    Eur Heart J 24:1531-7. 2003
    ..To investigate the long-term effects of central fat mass (CFM) and peripheral fat mass (PFM) on atherogenic risk profile and the progression of aortic calcification (AC) in postmenopausal women...
  14. ncbi request reprint Axial stretch modifies contractility of porcine coronary arteries by a protein kinase C-dependent mechanism
    L B Tanko
    Department of Pharmacology, University of Aarhus, Denmark
    Pharmacol Toxicol 88:89-97. 2001
    ..These results suggest that axial stretch of the vessel wall enhances the sensitivity of coronary arteries to vasoconstrictors by a protein kinase C-dependent mechanism...
  15. ncbi request reprint The effect of hormone replacement therapy on appendicular lean tissue mass in early postmenopausal women
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    Menopause 9:117-21. 2002
    ..The aim of the present preliminary study was to evaluate the effect of a 3-year HRT program on appendicular lean tissue mass (LTM(A)) in early postmenopausal women aged 45-54 years...
  16. ncbi request reprint Serum placental protein 14: a novel marker of selective oestrogen receptor modulator action on the postmenopausal endometrium
    Laszlo B Tanko
    Centre for Clinical and Basic Research A S, Ballerup Byvej 222, DK 2750 Ballerup, Denmark
    Biomarkers 7:257-66. 2002
    ....
  17. ncbi request reprint Does serum cholesterol contribute to vertebral bone loss in postmenopausal women?
    L B Tanko
    The PERF Study Group, Center for Clinical and Basic Research A S, Hobrovej 42D, 9000 Aalborg, Ballerup, Denmark
    Bone 32:8-14. 2003
    ....
  18. ncbi request reprint Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women
    Laszlo B Tanko
    Center for Clinical and Basic Research, Ballerup Byvej 222, DK 2750 Ballerup, Denmark
    Circulation 107:1626-31. 2003
    ..Although several lines of evidence point to an atherogenic role of central fat mass (CFM), few data are available to address the specific role played by peripheral fat mass (PFM)...
  19. ncbi request reprint The efficacy of 48-week oral ibandronate treatment in postmenopausal osteoporosis when taken 30 versus 60 minutes before breakfast
    L B Tanko
    Center for Clinical and Basic Research A S, Ballerup and Aalborg, Denmark
    Bone 32:421-6. 2003
    ..Another potential solution for improving the convenience with bisphosphonate treatment is expected from weekly or monthly dosing regimens currently under clinical investigations...
  20. ncbi request reprint Oral ibandronate: changes in markers of bone turnover during adequately dosed continuous and weekly therapy and during different suboptimally dosed treatment regimens
    L B Tanko
    Center for Clinical and Basic Research A S, Ballerup Byvej 222, 2750 Ballerup, Denmark
    Bone 32:687-93. 2003
    ..These observations suggest that serial measurements of s-CTX may provide a useful diagnostic tool for the early revelation of suboptimal dosing or noncompliance to already optimized therapies with antiresorptive agents...
  21. ncbi request reprint Dose dependent effects on bone resorption and formation of intermittently administered intravenous ibandronate
    C Christiansen
    Center for Clinical and Basic Research A S, Ballerup Byvej 222, 2750, Ballerup, Denmark
    Osteoporos Int 14:609-13. 2003
    ....
  22. ncbi request reprint Adipose tissue, insulin resistance and low-grade inflammation: implications for atherogenesis and the cardiovascular harm of estrogen plus progestogen therapy
    L B Tanko
    Center for Clinical and Basic Research, Ballerup, Denmark
    Climacteric 9:169-80. 2006
    ....
  23. pmc Cartilage turnover assessed with a newly developed assay measuring collagen type II degradation products: influence of age, sex, menopause, hormone replacement therapy, and body mass index
    U Mouritzen
    Centre for Clinical and Basic Research A S, Ballerup, Denmark
    Ann Rheum Dis 62:332-6. 2003
    ..Cartilage normally has a slow turnover but in arthritis increased metabolism results in degradation of the tissue...
  24. pmc Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se?
    Y Z Bagger
    Center for Clinical and Basic Research A S, Ballerup Byvej 222, DK 2750, Ballerup, Denmark
    Osteoporos Int 18:505-12. 2007
    ..We investigated whether serum lipids and polymorphism in the ApoE gene modifying serum lipids could be a biological linkage...
  25. ncbi request reprint Radiographic measure of aorta calcification is a site-specific predictor of bone loss and fracture risk at the hip
    Y Z Bagger
    Center for Clinical and Basic Research A S, Ballerup, Denmark
    J Intern Med 259:598-605. 2006
    ..To investigate whether aorta calcification (AC) - a surrogate marker of atherosclerosis - is an independent indicator of low bone mass density (BMD), accelerated bone loss, and risk of future fractures in postmenopausal women...
  26. ncbi request reprint Oral weekly ibandronate prevents bone loss in postmenopausal women
    L B Tanko
    Center for Clinical and Basic Research A S, Ballerup and Vejle, Denmark
    J Intern Med 254:159-67. 2003
    ..To investigate the efficacy, safety, and dose-response of once-weekly oral ibandronate in the prevention of postmenopausal bone loss...
  27. ncbi request reprint Vascular reactivity to nifedipine and Ca(2+) in vitro: the role of preactivation, wall tension and geometry
    L B Tanko
    Department of Pharmacology, Aarhus University, The Bartholin Building 240, DK 8000, Aarhus, Denmark
    Eur J Pharmacol 387:303-12. 2000
    ..Furthermore, axial wall tension appears to be a modulator of nifedipine-insensitive transmembrane Ca(2+)-influx that may play a role for the tone and reactivity in large coronary arteries...
  28. ncbi request reprint The long-term impact of 2-3 years of hormone replacement therapy on cardiovascular mortality and atherosclerosis in healthy women
    P Alexandersen
    Center for Clinical and Basic Research, Ballerup, Denmark
    Climacteric 9:108-18. 2006
    ..The aim of this study was to investigate the long-term effects of HRT given for a few years on all-cause and cardiovascular mortality and the severity of atherosclerosis...
  29. pmc A new experimental approach in endothelium-dependent pharmacological investigations on isolated porcine coronary arteries mounted for impedance planimetry
    L B Tanko
    Department of Pharmacology, University of Aarhus, The Bartholin Building, DK 8000 Aarhus C, Denmark
    Br J Pharmacol 128:165-73. 1999
    ....
  30. ncbi request reprint A computer-based measure of irregularity in vertebral alignment is a BMD-independent predictor of fracture risk in postmenopausal women
    P C Pettersen
    Center for Clinical and Basic Research, Ballerup Byvej 222, 2750 Ballerup, Denmark
    Osteoporos Int 18:1525-30. 2007
    ....
  31. doi request reprint Parallel assessment of the impact of different hormone replacement therapies on breast density by radiologist- and computer-based analyses of mammograms
    P C Pettersen
    Center for Clinical and Basic Research, Ballerup, Denmark
    Climacteric 11:135-43. 2008
    ..First, to compare the impact of nasally and orally dosed estradiol on breast density; second, to investigate the utility of computer-based automated approaches to the assessment of breast density with reference to traditional methods...