Research Topics
| Mette V LarsenSummaryAffiliation: Center for Biological Sequence Analysis Country: Denmark Publications
| Collaborators
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Detail Information
Publications
Multilocus sequence typing of total-genome-sequenced bacteriaMette V Larsen
Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
J Clin Microbiol 50:1355-61. 2012..The method presented here enables investigators to determine the sequence types of their isolates on the basis of WGS data. This method is publicly available at www.cbs.dtu.dk/services/MLST...
Identification of CD8+ T cell epitopes in the West Nile virus polyprotein by reverse-immunology using NetCTLMette Voldby Larsen
Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
PLoS ONE 5:e12697. 2010..West Nile virus (WNV) is a growing threat to public health and a greater understanding of the immune response raised against WNV is important for the development of prophylactic and therapeutic strategies...
Large-scale validation of methods for cytotoxic T-lymphocyte epitope predictionMette V Larsen
Center for Biological Sequence Analysis, BioCentrum DTU, Building 208, Technical University of Denmark, DK 2800 Lyngby, Denmark
BMC Bioinformatics 8:424. 2007..Here, we develop such large-scale benchmark and corresponding performance measures and report the performance of an updated version 1.2 of NetCTL in comparison with the four other methods...
The cancer exome generated by alternative mRNA splicing dilutes predicted HLA class I epitope densityThomas Stranzl
Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
PLoS ONE 7:e38670. 2012..This variation contributes to the observed significant lower likelihood of cancer-specific peptides to be predicted epitopes compared to peptides found in normal tissue...
Systematic characterisation of cellular localisation and expression profiles of proteins containing MHC ligandsAgnieszka S Juncker
Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
PLoS ONE 4:e7448. 2009..Presentation of peptides on Major Histocompatibility Complex (MHC) molecules is the cornerstone in immune system activation and increased knowledge of the characteristics of MHC ligands and their source proteins is highly desirable...
