Ilka Hoof

Summary

Affiliation: Center for Biological Sequence Analysis
Country: Denmark

Publications

  1. pmc Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution
    Christian Rausch
    Center for Bioinformatics Tübingen ZBIT, Eberhard Karls Universitat Tubingen, Sand 14, Tubingen, Germany
    BMC Evol Biol 7:78. 2007
  2. doi request reprint Humans with chimpanzee-like major histocompatibility complex-specificities control HIV-1 infection
    Ilka Hoof
    Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
    AIDS 22:1299-303. 2008
  3. pmc NetMHCpan, a method for MHC class I binding prediction beyond humans
    Ilka Hoof
    Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Building 208, 2800, Lyngby, Denmark
    Immunogenetics 61:1-13. 2009
  4. doi request reprint Interdisciplinary analysis of HIV-specific CD8+ T cell responses against variant epitopes reveals restricted TCR promiscuity
    Ilka Hoof
    Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Lyngby, Denmark
    J Immunol 184:5383-91. 2010
  5. pmc SigniSite: Identification of residue-level genotype-phenotype correlations in protein multiple sequence alignments
    Leon Eyrich Jessen
    Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Kemitorvet, Building 208, DK 2800 Lyngby, Denmark
    Nucleic Acids Res 41:W286-91. 2013
  6. pmc MHC motif viewer
    Nicolas Rapin
    Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
    Immunogenetics 60:759-65. 2008
  7. pmc Identification of CD8+ T cell epitopes in the West Nile virus polyprotein by reverse-immunology using NetCTL
    Mette Voldby Larsen
    Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
    PLoS ONE 5:e12697. 2010
  8. pmc State of the art and challenges in sequence based T-cell epitope prediction
    Claus Lundegaard
    The Technical University of Denmark DTU, Dept, of Systems Biology, Center for Biological Sequence Analysis CBS, Kemitorvet 208, DK 2800 Kgs, Lyngby, Denmark
    Immunome Res 6:S3. 2010

Collaborators

Detail Information

Publications8

  1. pmc Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution
    Christian Rausch
    Center for Bioinformatics Tübingen ZBIT, Eberhard Karls Universitat Tubingen, Sand 14, Tubingen, Germany
    BMC Evol Biol 7:78. 2007
    ..The homologous Epimerization (E) domain flips the chirality of the last amino acid in the growing peptide; Dual E/C domains catalyze both epimerization and condensation...
  2. doi request reprint Humans with chimpanzee-like major histocompatibility complex-specificities control HIV-1 infection
    Ilka Hoof
    Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
    AIDS 22:1299-303. 2008
    ..Chimpanzees control HIV-1 viral replication and develop a chronic infection without progressing to AIDS. A similar course of disease is observed in human long-term non-progressors...
  3. pmc NetMHCpan, a method for MHC class I binding prediction beyond humans
    Ilka Hoof
    Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Building 208, 2800, Lyngby, Denmark
    Immunogenetics 61:1-13. 2009
    ..The high performance of NetMHCpan-2.0 for non-human primates documents the method's ability to provide broad allelic coverage also beyond human MHC molecules. The method is available at http://www.cbs.dtu.dk/services/NetMHCpan...
  4. doi request reprint Interdisciplinary analysis of HIV-specific CD8+ T cell responses against variant epitopes reveals restricted TCR promiscuity
    Ilka Hoof
    Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Lyngby, Denmark
    J Immunol 184:5383-91. 2010
    ....
  5. pmc SigniSite: Identification of residue-level genotype-phenotype correlations in protein multiple sequence alignments
    Leon Eyrich Jessen
    Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Kemitorvet, Building 208, DK 2800 Lyngby, Denmark
    Nucleic Acids Res 41:W286-91. 2013
    ..For both data sets, SigniSite was found to outperform SPEER. SigniSite is available at: http://www.cbs.dtu.dk/services/SigniSite/. ..
  6. pmc MHC motif viewer
    Nicolas Rapin
    Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
    Immunogenetics 60:759-65. 2008
    ..The MHC motif viewer is available at http://www.cbs.dtu.dk/biotools/MHCMotifViewer/ ...
  7. pmc Identification of CD8+ T cell epitopes in the West Nile virus polyprotein by reverse-immunology using NetCTL
    Mette Voldby Larsen
    Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
    PLoS ONE 5:e12697. 2010
    ..West Nile virus (WNV) is a growing threat to public health and a greater understanding of the immune response raised against WNV is important for the development of prophylactic and therapeutic strategies...
  8. pmc State of the art and challenges in sequence based T-cell epitope prediction
    Claus Lundegaard
    The Technical University of Denmark DTU, Dept, of Systems Biology, Center for Biological Sequence Analysis CBS, Kemitorvet 208, DK 2800 Kgs, Lyngby, Denmark
    Immunome Res 6:S3. 2010
    ..Here, we will go through some of the history of sequence-based predictions of helper as well as cytotoxic T cell epitopes. We will focus on some of the most accurate methods and their basic background...