Laurent Gautier

Summary

Affiliation: Center for Biological Sequence Analysis
Country: Denmark

Publications

  1. pmc Low-bandwidth and non-compute intensive remote identification of microbes from raw sequencing reads
    Laurent Gautier
    Center for Biological Sequence Analysis CBS, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark DTU Multiassay Core DMAC, Technical University of Denmark, Lyngby, Denmark
    PLoS ONE 8:e83784. 2013
  2. pmc Bioconductor: open software development for computational biology and bioinformatics
    Robert C Gentleman
    Department of Biostatistical Science, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    Genome Biol 5:R80. 2004
  3. ncbi request reprint affy--analysis of Affymetrix GeneChip data at the probe level
    Laurent Gautier
    Center for Biological Sequence Analysis CBS, Technical University of Denmark, Building 208, 2800 Lyngby, Denmark
    Bioinformatics 20:307-15. 2004
  4. pmc Alternative mapping of probes to genes for Affymetrix chips
    Laurent Gautier
    Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark
    BMC Bioinformatics 5:111. 2004
  5. pmc An intuitive Python interface for Bioconductor libraries demonstrates the utility of language translators
    Laurent Gautier
    DMAC, Centre for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Matematiktorvet, 2100 Lyngby, Denmark
    BMC Bioinformatics 11:S11. 2010
  6. ncbi request reprint Implementation of a gene expression index calculation method based on the PDNN model
    Henrik Bjørn Nielsen
    Center for Biological Sequence Analysis, BioCentrum DTU Technical University of Denmark Building 208, DK 2800 Lyngby, Denmark
    Bioinformatics 21:687-8. 2005
  7. ncbi request reprint The effect of network biology on drug toxicology
    Laurent Gautier
    Technical University of Denmark, Center for Biological Sequence Analysis, Department of Systems Biology, Lyngby, Denmark
    Expert Opin Drug Metab Toxicol 9:1409-18. 2013
  8. pmc A new non-linear normalization method for reducing variability in DNA microarray experiments
    Christopher Workman
    Genedata AG, Basel, Switzerland
    Genome Biol 3:research0048. 2002

Collaborators

Detail Information

Publications8

  1. pmc Low-bandwidth and non-compute intensive remote identification of microbes from raw sequencing reads
    Laurent Gautier
    Center for Biological Sequence Analysis CBS, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark DTU Multiassay Core DMAC, Technical University of Denmark, Lyngby, Denmark
    PLoS ONE 8:e83784. 2013
    ..A web access is available at http://tapir.cbs.dtu.dk. The source code for a python command-line client, a server, and supplementary data are available at http://bit.ly/1aURxkc...
  2. pmc Bioconductor: open software development for computational biology and bioinformatics
    Robert C Gentleman
    Department of Biostatistical Science, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    Genome Biol 5:R80. 2004
    ..We describe details of our aims and methods, identify current challenges, compare Bioconductor to other open bioinformatics projects, and provide working examples...
  3. ncbi request reprint affy--analysis of Affymetrix GeneChip data at the probe level
    Laurent Gautier
    Center for Biological Sequence Analysis CBS, Technical University of Denmark, Building 208, 2800 Lyngby, Denmark
    Bioinformatics 20:307-15. 2004
    ..The processing of the Affymetrix GeneChip data has been a recent focus for data analysts. Alternatives to the original procedure have been proposed and some of these new methods are widely used...
  4. pmc Alternative mapping of probes to genes for Affymetrix chips
    Laurent Gautier
    Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark
    BMC Bioinformatics 5:111. 2004
    ..However, once probes have been selected and synthesized on an array, it is still possible to re-evaluate the results using an updated mapping of probes to genes, taking into account the latest biological knowledge available...
  5. pmc An intuitive Python interface for Bioconductor libraries demonstrates the utility of language translators
    Laurent Gautier
    DMAC, Centre for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Matematiktorvet, 2100 Lyngby, Denmark
    BMC Bioinformatics 11:S11. 2010
    ..At the same time, Python has matured as a rich and reliable language for the agile development of prototypes or final implementations, as well as for handling large data sets...
  6. ncbi request reprint Implementation of a gene expression index calculation method based on the PDNN model
    Henrik Bjørn Nielsen
    Center for Biological Sequence Analysis, BioCentrum DTU Technical University of Denmark Building 208, DK 2800 Lyngby, Denmark
    Bioinformatics 21:687-8. 2005
    ..2003). Here we describe an open source implementation of the PDNN method for the statistical language R...
  7. ncbi request reprint The effect of network biology on drug toxicology
    Laurent Gautier
    Technical University of Denmark, Center for Biological Sequence Analysis, Department of Systems Biology, Lyngby, Denmark
    Expert Opin Drug Metab Toxicol 9:1409-18. 2013
    ..With this approach, the assessment of chemical safety can be done across multiple scales of complexity from molecular to cellular and system levels in human health. Network biology can be used at several levels of complexity...
  8. pmc A new non-linear normalization method for reducing variability in DNA microarray experiments
    Christopher Workman
    Genedata AG, Basel, Switzerland
    Genome Biol 3:research0048. 2002
    ..Current normalization techniques are most often linear and therefore not capable of fully correcting for these effects...