Christian Torp-Pedersen

Summary

Affiliation: Bispebjerg University Hospital
Country: Denmark

Publications

  1. ncbi request reprint The incomplete bucindolol evaluation in acute myocardial infarction Trial (BEAT)
    Christian Torp-Pedersen
    Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
    Eur J Heart Fail 4:495-9. 2002
  2. pmc Effects of metoprolol and carvedilol on pre-existing and new onset diabetes in patients with chronic heart failure: data from the Carvedilol Or Metoprolol European Trial (COMET)
    Christian Torp-Pedersen
    Department of Cardiology, Bispebjerg University Hospital, Copenhagen NV, Denmark
    Heart 93:968-73. 2007
  3. ncbi request reprint Cardiovascular responses to weight management and sibutramine in high-risk subjects: an analysis from the SCOUT trial
    Christian Torp-Pedersen
    Department of Cardiology, Bispebjerg University Hospital, Bispebjerg Bakke 23, Copenhagen 2400 NV, Denmark
    Eur Heart J 28:2915-23. 2007
  4. pmc Significance of K(ATP) channels, L-type Ca²⁺ channels and CYP450-4A enzymes in oxygen sensing in mouse cremaster muscle arterioles in vivo
    Anh Thuc Ngo
    Department of Biomedical Sciences, Faculty of Health and Medical Sciences, The Panum Institute, University of Copenhagen, Blegdamsvej 3, Copenhagen N, DK 2200, Denmark
    BMC Physiol 13:8. 2013
  5. pmc Prognosis after percutaneous coronary intervention in patients with psoriasis: a cohort study using Danish nationwide registries
    Ole Ahlehoff
    Department of Cardiology, Copenhagen University Hospital, Gentofte, Hellerup DK 2900, Denmark
    BMC Cardiovasc Disord 12:79. 2012
  6. doi request reprint Vernakalant: conversion of atrial fibrillation in patients with ischemic heart disease
    Christian Torp-Pedersen
    Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
    Int J Cardiol 166:147-51. 2013
  7. pmc Differential changes in serum uric acid concentrations in sibutramine promoted weight loss in diabetes: results from four weeks of the lead-in period of the SCOUT trial
    Charlotte Andersson
    Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
    Nutr Metab (Lond) 6:42. 2009
  8. pmc Predictors of right ventricular function as measured by tricuspid annular plane systolic excursion in heart failure
    Jesper Kjaergaard
    The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Cardiovasc Ultrasound 7:51. 2009
  9. pmc Endothelial function is unaffected by changing between carvedilol and metoprolol in patients with heart failure--a randomized study
    Britt Falskov
    Department of Cardiology, Gentofte Hospital, Hellerup, Denmark
    Cardiovasc Diabetol 10:91. 2011
  10. pmc Diabetes is an independent predictor of survival 17 years after myocardial infarction: follow-up of the TRACE registry
    Thomas Kümler
    Department of Cardiology, Rigshopitalet University Hospital, Blegdamsvej, Copenhagen, Denmark
    Cardiovasc Diabetol 9:22. 2010

Collaborators

Detail Information

Publications146 found, 100 shown here

  1. ncbi request reprint The incomplete bucindolol evaluation in acute myocardial infarction Trial (BEAT)
    Christian Torp-Pedersen
    Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
    Eur J Heart Fail 4:495-9. 2002
    ..The aim of this study was to evaluate the efficacy of adding the beta-blocker bucindolol to standard therapy shortly after a myocardial infarction in a high-risk population with reduced left ventricular function...
  2. pmc Effects of metoprolol and carvedilol on pre-existing and new onset diabetes in patients with chronic heart failure: data from the Carvedilol Or Metoprolol European Trial (COMET)
    Christian Torp-Pedersen
    Department of Cardiology, Bispebjerg University Hospital, Copenhagen NV, Denmark
    Heart 93:968-73. 2007
    ..Beta blocker treatment may worsen glucose metabolism...
  3. ncbi request reprint Cardiovascular responses to weight management and sibutramine in high-risk subjects: an analysis from the SCOUT trial
    Christian Torp-Pedersen
    Department of Cardiology, Bispebjerg University Hospital, Bispebjerg Bakke 23, Copenhagen 2400 NV, Denmark
    Eur Heart J 28:2915-23. 2007
    ..The study had an initial single-blind, 6-week lead-in period with sibutramine plus weight management. We report the cardiovascular responses and weight loss during this period...
  4. pmc Significance of K(ATP) channels, L-type Ca²⁺ channels and CYP450-4A enzymes in oxygen sensing in mouse cremaster muscle arterioles in vivo
    Anh Thuc Ngo
    Department of Biomedical Sciences, Faculty of Health and Medical Sciences, The Panum Institute, University of Copenhagen, Blegdamsvej 3, Copenhagen N, DK 2200, Denmark
    BMC Physiol 13:8. 2013
    ..For this purpose we utilized the exteriorized cremaster muscle of anesthetized mice, in which the cremaster muscle was exposed to controlled perturbation of tissue PO₂...
  5. pmc Prognosis after percutaneous coronary intervention in patients with psoriasis: a cohort study using Danish nationwide registries
    Ole Ahlehoff
    Department of Cardiology, Copenhagen University Hospital, Gentofte, Hellerup DK 2900, Denmark
    BMC Cardiovasc Disord 12:79. 2012
    ..Psoriasis is an inflammatory disease associated with increased risk of coronary artery disease. However, the potential impact of psoriasis on the prognosis following percutaneous coronary revascularization (PCI) is unknown...
  6. doi request reprint Vernakalant: conversion of atrial fibrillation in patients with ischemic heart disease
    Christian Torp-Pedersen
    Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
    Int J Cardiol 166:147-51. 2013
    ..This analysis assessed the efficacy and safety of intravenous vernakalant for the rapid conversion of atrial fibrillation (AF) to sinus rhythm in patients with a history of ischemic heart disease (IHD)...
  7. pmc Differential changes in serum uric acid concentrations in sibutramine promoted weight loss in diabetes: results from four weeks of the lead-in period of the SCOUT trial
    Charlotte Andersson
    Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
    Nutr Metab (Lond) 6:42. 2009
    ..abstract:..
  8. pmc Predictors of right ventricular function as measured by tricuspid annular plane systolic excursion in heart failure
    Jesper Kjaergaard
    The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Cardiovasc Ultrasound 7:51. 2009
    ..The present study assessed the association of TAPSE and clinical factors, global and regional LV function in 634 patients admitted for symptomatic heart failure...
  9. pmc Endothelial function is unaffected by changing between carvedilol and metoprolol in patients with heart failure--a randomized study
    Britt Falskov
    Department of Cardiology, Gentofte Hospital, Hellerup, Denmark
    Cardiovasc Diabetol 10:91. 2011
    ....
  10. pmc Diabetes is an independent predictor of survival 17 years after myocardial infarction: follow-up of the TRACE registry
    Thomas Kümler
    Department of Cardiology, Rigshopitalet University Hospital, Blegdamsvej, Copenhagen, Denmark
    Cardiovasc Diabetol 9:22. 2010
    ..The aim of this study was to systematically evaluate the development of diabetes as an independent long-term prognostic factor after myocardial infarction...
  11. pmc Metoprolol compared to carvedilol deteriorates insulin-stimulated endothelial function in patients with type 2 diabetes - a randomized study
    Britt Kveiborg
    Department of Medicine, Naestved Hospital, Naestved, Denmark
    Cardiovasc Diabetol 9:21. 2010
    ..The aim of this study was to examine the effect of metoprolol versus carvedilol on endothelial function and insulin-stimulated endothelial function in patients with type 2 diabetes...
  12. pmc Hereditary hemochromatosis (HFE) genotypes in heart failure: relation to etiology and prognosis
    Daniel V Møller
    Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    BMC Med Genet 11:117. 2010
    ..Mutations within several genes are HH-associated, the most common being the HFE gene. In a large cohort of HF patients, we sought to determine the etiological role and the prognostic significance of HFE genotypes...
  13. pmc The weight lowering effect of sibutramine and its impact on serum lipids in cardiovascular high risk patients with and without type 2 diabetes mellitus - an analysis from the SCOUT lead-in period
    Peter Weeke
    Department of Cardiology, Gentofte Hospital, University of Copenhagen, Denmark
    BMC Endocr Disord 10:3. 2010
    ..We examined whether blood lipid changes with short term administration of the weight lowering drug, sibutramine and lifestyle modification in obese and overweight high-risk patients was associated with T2D status at screening...
  14. pmc Renal function at the time of a myocardial infarction maintains prognostic value for more than 10 years
    Thomas Kümler
    Dept of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark
    BMC Cardiovasc Disord 11:37. 2011
    ..We examined the importance of renal function by estimated GFR (eGFR) and se-creatinine as an independent long-term prognostic factor...
  15. pmc Duration of clopidogrel treatment and risk of mortality and recurrent myocardial infarction among 11 680 patients with myocardial infarction treated with percutaneous coronary intervention: a cohort study
    Rikke Sørensen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    BMC Cardiovasc Disord 10:6. 2010
    ..We studied the risk of death or recurrent myocardial infarction (MI) in relation to 6- and 12-months clopidogrel treatment among MI patients treated with PCI...
  16. pmc Increased susceptibility to cardiovascular effects of dihydrocapcaicin in resuscitated rats. Cardiovascular effects of dihydrocapsaicin
    Keld Fosgerau
    Neurokey AS, Diplomvej 372, DK 2800 Lyngby, Denmark
    BMC Cardiovasc Disord 10:39. 2010
    ..These cardiovascular derangements may lead to an increased susceptibility towards the external and internal environment of the cardiovascular system as compared to the healthy situation...
  17. pmc Drug-induced mild therapeutic hypothermia obtained by administration of a transient receptor potential vanilloid type 1 agonist
    Keld Fosgerau
    Neurokey AS, Diplomvej 372, DK 2800 Lyngby, Denmark
    BMC Cardiovasc Disord 10:51. 2010
    ..We investigated the feasibility of using a transient receptor potential vanilloid type 1 (TRPV1) agonist for obtaining drug-induced sustainable mild hypothermia...
  18. ncbi request reprint [A randomized comparison of carvedilol and metoprolol in patients with chronic heart failure. The Carvedilol Or Metoprolol European Trial (COMET) ]
    Christian T Torp-Pedersen
    H S Bispebjerg Hospital, Kardiologisk Klinik Y, København
    Ugeskr Laeger 166:2671-4. 2004
  19. ncbi request reprint Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET
    Christian Torp-Pedersen
    Department of Cardiology, Bispebjerg University Hospital, Copenhagen, Denmark
    Am Heart J 149:370-6. 2005
    ..Beta-blockers with different receptor bindings reduce mortality in patients with chronic heart failure. We compared the effects of the beta1-blocker metoprolol tartrate and the beta1-, beta2-, and alpha1-blocker carvedilol...
  20. pmc Impact of dronedarone on hospitalization burden in patients with atrial fibrillation: results from the ATHENA study
    Christian Torp-Pedersen
    Department of Cardiology, Gentofte Hospital, University of Copenhagen, 2009 Hellerup, Denmark
    Europace 13:1118-26. 2011
    ..This post hoc analysis evaluated the secondary endpoint of CV hospitalization and the clinical benefit of dronedarone on the number and duration of CV hospitalizations in patients with atrial fibrillation (AF)...
  21. ncbi request reprint Dofetilide: a class III anti-arrhythmic drug for the treatment of atrial fibrillation
    C Torp-Pedersen
    Department of Cardiology, Gentofte University Hospital, 2900 Hellerup, Copenhagen, Denmark
    Expert Opin Investig Drugs 9:2695-704. 2000
    ..In the setting of severe heart failure and large myocardial infarctions, only amiodarone and dofetilide have proven safety and dofetilide is a strong candidate for first choice treatment when the aim is to achieve sinus rhythm...
  22. doi request reprint A randomized, placebo-controlled study of vernakalant (oral) for the prevention of atrial fibrillation recurrence after cardioversion
    Christian Torp-Pedersen
    Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
    Circ Arrhythm Electrophysiol 4:637-43. 2011
    ..This study was designed to determine the most appropriate oral dose of vernakalant for the prevention of AF recurrence postcardioversion...
  23. ncbi request reprint Effect of ACE inhibitor trandolapril on life expectancy of patients with reduced left-ventricular function after acute myocardial infarction. TRACE Study Group. Trandolapril Cardiac Evaluation
    C Torp-Pedersen
    Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
    Lancet 354:9-12. 1999
    ..We aimed to calculate the effect of trandolapril on life expectancy with follow-up data from the Trandolapril Cardiac Evaluation (TRACE) Study...
  24. doi request reprint A randomised trial of a pre-synaptic stimulator of DA2-dopaminergic and alpha2-adrenergic receptors on morbidity and mortality in patients with heart failure
    Christian Torp-Pedersen
    Dept Cardiology, Bispebjerg University Hospital, Bispebjerg Bakke, 2400 Copenhagen NV, Denmark
    Eur J Heart Fail 10:89-95. 2008
    ..We performed a clinical study with nolomirole in patients with heart failure (HF)...
  25. ncbi request reprint [Angiotensin-converting enzyme inhibitors after AMI]
    C T Torp-Pedersen
    Kardiologisk Afdeling P, Amtssygehuset i Gentofte
    Ugeskr Laeger 163:32-5. 2001
    ..In the trandolapril group median lifetime was increased by 15.3 months or 27% (7-51%). We conclude that the increase in lifetime by treatment of patients with left ventricular dysfunction after a myocardial infarction is substantial...
  26. ncbi request reprint Risk of death or reinfarction associated with the use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs after acute myocardial infarction
    Gunnar H Gislason
    Department of Cardiology, Gentofte University Hospital, DK 2900 Hellerup, Denmark
    Circulation 113:2906-13. 2006
    ..We analyzed the risk of rehospitalization for acute myocardial infarction (MI) and death related to the use of NSAIDs including selective COX-2 inhibitors in patients with prior MI...
  27. doi request reprint Calcium-channel blockers do not alter the clinical efficacy of clopidogrel after myocardial infarction: a nationwide cohort study
    Jonas B Olesen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    J Am Coll Cardiol 57:409-17. 2011
    ..The purpose of this study was to determine the risk of adverse cardiovascular events associated with concomitant use of clopidogrel and calcium-channel blockers (CCBs) in patients with myocardial infarction (MI)...
  28. ncbi request reprint Nationwide trends in the prescription of beta-blockers and angiotensin-converting enzyme inhibitors after myocardial infarction in Denmark, 1995-2002
    Gunnar H Gislason
    Department of Cardiovascular Medicine, Bispebjerg University Hospital, Copenhagen, Denmark
    Scand Cardiovasc J 39:42-9. 2005
    ..To study the use of beta-blockers and angiotensin-converting enzyme (ACE) inhibitors after acute myocardial infarction (AMI) in Denmark from 1995 to 2002...
  29. doi request reprint Bleeding after initiation of multiple antithrombotic drugs, including triple therapy, in atrial fibrillation patients following myocardial infarction and coronary intervention: a nationwide cohort study
    Morten Lamberts
    Department of Cardiology, Post 635, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Circulation 126:1185-93. 2012
    ..We investigated the risk and time frame for bleeding following myocardial infarction/percutaneous coronary intervention in patients with atrial fibrillation according to antithrombotic treatment...
  30. doi request reprint Diabetes patients requiring glucose-lowering therapy and nondiabetics with a prior myocardial infarction carry the same cardiovascular risk: a population study of 3.3 million people
    Tina Ken Schramm
    Department of Cardiology, Gentofte University Hospital, Niels Andersens Vej 65, DK 2900, Hellerup, Denmark
    Circulation 117:1945-54. 2008
    ..Previous studies reveal major differences in the estimated cardiovascular risk in diabetes mellitus, including uncertainty about the risk in young patients. Therefore, large studies of well-defined populations are needed...
  31. pmc The prognostic importance of a history of hypertension in patients with symptomatic heart failure is substantially worsened by a short mitral inflow deceleration time
    Charlotte Andersson
    Department of Cardiology, Gentofte Hospital, Hellerup, Denmark
    BMC Cardiovasc Disord 12:30. 2012
    ..Hypertension is a common comorbidity in patients with heart failure and may contribute to development and course of disease, but the importance of a history of hypertension in patients with prevalent heart failure remains uncertain...
  32. doi request reprint Vascular disease and stroke risk in atrial fibrillation: a nationwide cohort study
    Jonas Bjerring Olesen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Am J Med 125:826.e13-23. 2012
    ....
  33. doi request reprint Stroke and bleeding in atrial fibrillation with chronic kidney disease
    Jonas Bjerring Olesen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    N Engl J Med 367:625-35. 2012
    ..However, these risks, and the effects of antithrombotic treatment, have not been thoroughly investigated in patients with both conditions...
  34. pmc Temporal trends in the initiation of glucose-lowering medications after a first-time myocardial infarction - a nationwide study between 1997 and 2006
    Mette L Norgaard
    Department of Cardiology, University Hospital of Copenhagen, Gentofte, Denmark
    Cardiovasc Diabetol 10:5. 2011
    ..The aim of the study was to investigate temporal trends in the initiation of GLM among patients discharged after first-time MI...
  35. doi request reprint Risks of thromboembolism and bleeding with thromboprophylaxis in patients with atrial fibrillation: A net clinical benefit analysis using a 'real world' nationwide cohort study
    Jonas Bjerring Olesen
    Department of Cardiology, Post 635, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Thromb Haemost 106:739-49. 2011
    ..Also, the risk of bleeding was increased with both VKA and ASA treatment, but the net clinical benefit was clearly positive, in favour of VKA in patients with increased risk of stroke/thromboembolism...
  36. doi request reprint Efficacy of post-operative clopidogrel treatment in patients revascularized with coronary artery bypass grafting after myocardial infarction
    Rikke Sørensen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Copenhagen, Denmark
    J Am Coll Cardiol 57:1202-9. 2011
    ..The objective of this study was to examine the clinical efficacy of clopidogrel treatment on death and recurrent myocardial infarction (MI) among MI patients revascularized by coronary artery bypass graft surgery (CABG)...
  37. doi request reprint Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillation
    Morten L Hansen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65 2900, Hellerup, Copenhagen, Denmark
    Arch Intern Med 170:1433-41. 2010
    ..Patients with atrial fibrillation (AF) often require anticoagulation and platelet inhibition, but data are limited on the bleeding risk of combination therapy...
  38. doi request reprint Obesity is a risk factor for atrial fibrillation among fertile young women: a nationwide cohort study
    Deniz Karasoy
    Department of Cardiology post 635, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Europace 15:781-6. 2013
    ..We therefore investigated the risk of AF in relation to body mass index (BMI) among young fertile women...
  39. doi request reprint Comparison of incidence, predictors, and the impact of co-morbidity and polypharmacy on the risk of recurrent syncope in patients <85 versus ≥85 years of age
    Martin Huth Ruwald
    Department of Cardiology, Gentofte Hospital, Hellerup, Denmark Division of Cardiology, Heart Research Follow Up Program, University of Rochester Medical Center, Rochester, New York Electronic address
    Am J Cardiol 112:1610-5. 2013
    ..The use of multiple orthostatic medications additively increased the risk of recurrences representing a need for strategies to reduce unnecessary polypharmacy...
  40. doi request reprint Proton-pump inhibitors are associated with increased cardiovascular risk independent of clopidogrel use: a nationwide cohort study
    Mette Charlot
    Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Ann Intern Med 153:378-86. 2010
    ..Controversy remains on whether the dual use of clopidogrel and proton-pump inhibitors (PPIs) affects clinical efficacy of clopidogrel...
  41. pmc Effects of oral glucose-lowering drugs on long term outcomes in patients with diabetes mellitus following myocardial infarction not treated with emergent percutaneous coronary intervention--a retrospective nationwide cohort study
    Casper H Jørgensen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Cardiovasc Diabetol 9:54. 2010
    ....
  42. doi request reprint Oral anticoagulation and antiplatelets in atrial fibrillation patients after myocardial infarction and coronary intervention
    Morten Lamberts
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    J Am Coll Cardiol 62:981-9. 2013
    ....
  43. doi request reprint Clopidogrel discontinuation after myocardial infarction and risk of thrombosis: a nationwide cohort study
    Mette Charlot
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Eur Heart J 33:2527-34. 2012
    ..We analysed the risk of adverse cardiovascular outcomes after discontinuation of 12 months of clopidogrel treatment...
  44. pmc The effect of chronic heart failure and type 2 diabetes on insulin-stimulated endothelial function is similar and additive
    Britt Falskov
    Department of Cardiology, Gentofte Hospital, Denmark
    Vasc Health Risk Manag 7:771-6. 2011
    ..The aim of this investigation was to study insulin-stimulated endothelial function and glucose uptake in skeletal muscles in patients with heart failure in comparison to patients with type 2 diabetes...
  45. doi request reprint Prognostic value of ambulatory heart rate revisited in 6928 subjects from 6 populations
    Tine W Hansen
    Research Center for Prevention and Health and Department of Clinical Physiology, Faculty of Health Sciences, Hvidovre University Hospital, Copenhagen, Denmark
    Hypertension 52:229-35. 2008
    ..With the exception of the night:day heart rate ratio, heart rate did not add to the risk stratification for fatal combined with nonfatal cardiovascular events. Thus, heart rate adds little to the prediction of cardiovascular risk...
  46. doi request reprint Heart failure severity, as determined by loop diuretic dosages, predicts the risk of developing diabetes after myocardial infarction: a nationwide cohort study
    Charlotte Andersson
    Department of Cardiology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, DK 2900 Hellerup, Denmark
    Eur J Heart Fail 12:1333-8. 2010
    ..The aim of the present study was to investigate the relationship between HF severity and risk of developing diabetes in a nationwide cohort of patients with myocardial infarction (MI)...
  47. doi request reprint Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data
    Rikke Sørensen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Lancet 374:1967-74. 2009
    ..However, data for the safety of combinations are sparse. We examined the risk of hospital admission for bleeding associated with different antithrombotic regimens...
  48. doi request reprint Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study
    Anne Marie Schjerning Olsen
    Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark
    Circulation 123:2226-35. 2011
    ..We therefore studied the duration of NSAID treatment and cardiovascular risk in a nationwide cohort of patients with prior myocardial infarction (MI)...
  49. pmc Cause-specific cardiovascular risk associated with nonsteroidal anti-inflammatory drugs among myocardial infarction patients--a nationwide study
    Anne Marie Schjerning Olsen
    Department of Cardiology, Copenhagen University Hospital, Hellerup, Denmark
    PLoS ONE 8:e54309. 2013
    ..Non steroidal anti-inflammatory drugs (NSAIDs) increase mortality and morbidity after myocardial infarction (MI). We examined cause-specific mortality and morbidity associated with NSAIDs in a nationwide cohort of MI patients...
  50. ncbi request reprint The relation between age, sex, comorbidity, and pharmacotherapy and the risk of syncope: a Danish nationwide study
    Martin Huth Ruwald
    Department of Cardiology, Copenhagen University Hospital Gentofte, Denmark
    Europace 14:1506-14. 2012
    ..The objective of this study was to determine the incidence, comorbidity, and pharmacotherapy in a nationwide cohort of patients hospitalized with syncope...
  51. doi request reprint Long-term cardiovascular risk of nonsteroidal anti-inflammatory drug use according to time passed after first-time myocardial infarction: a nationwide cohort study
    Anne Marie Schjerning Olsen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Circulation 126:1955-63. 2012
    ..We analyzed whether the cardiovascular risk associated with using nonsteroidal anti-inflammatory drugs (NSAIDs) was associated with the time elapsed following first-time MI...
  52. doi request reprint Prognostic value of reading-to-reading blood pressure variability over 24 hours in 8938 subjects from 11 populations
    Tine W Hansen
    Department of Clinical Physiology, Faculty of Health Sciences, Hvidovre University Hospital, Research Center for Prevention and Health, Copenhagen, Denmark
    Hypertension 55:1049-57. 2010
    ..In conclusion, in a large population cohort, which provided sufficient statistical power, BP variability assessed from 24-hour ambulatory recordings did not contribute much to risk stratification over and beyond 24-hour BP...
  53. ncbi request reprint The prognostic value of QTc interval and QT dispersion following myocardial infarction in patients treated with or without dofetilide
    Bente Brendorp
    Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark
    Clin Cardiol 26:219-25. 2003
    ..During the first year following MI, close to 50% of deaths are assumed to be due to arrhythmic events...
  54. ncbi request reprint Tetrahydrobiopterin restores endothelial dysfunction induced by an oral glucose challenge in healthy subjects
    Nikolaj Ihlemann
    Department of Cardiology, Bldg 40, Bispebjerg University Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen, Denmark
    Am J Physiol Heart Circ Physiol 285:H875-82. 2003
    ..0001). An oral glucose challenge causes transient, NO-specific, endothelial dysfunction, which may be reversed by BH4. Transient postprandial endothelial dysfunction may be partly explained by reduced bioavailability of BH4 and NO...
  55. doi request reprint Atrial fibrillation pharmacotherapy after hospital discharge between 1995 and 2004: a shift towards beta-blockers
    Morten Lock Hansen
    Department of Cardiology, Bispebjerg University Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen, Denmark
    Europace 10:395-402. 2008
    ..To study evolvement in pharmacotherapy of atrial fibrillation from 1995 to 2004...
  56. doi request reprint Prognosis in heart failure and the value of {beta}-blockers are altered by the use of antidepressants and depend on the type of antidepressants used
    Emil Loldrup Fosbøl
    Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
    Circ Heart Fail 2:582-90. 2009
    ..Guidelines recommend use of selective serotonin reuptake inhibitors (SSRIs), but knowledge of the prognostic effect of different classes of antidepressants is sparse...
  57. pmc Statin use after acute myocardial infarction: a nationwide study in Denmark
    Jeppe N Rasmussen
    National Institute of Public Health, Copenhagen, Denmark
    Br J Clin Pharmacol 60:150-8. 2005
    ..To study outpatient statin use after first acute myocardial infarction (AMI) in Denmark between 1995 and 2002 and to determine the predictors of statin use...
  58. doi request reprint Mortality and reinfarction among patients using different beta-blockers for secondary prevention after a myocardial infarction
    Søren Skøtt Andersen
    Department of Cardiology, Gentofte University Hospital, Niels Andersens Vej 65, Copenhagen, Denmark
    Cardiology 112:144-50. 2009
    ..To study differences in the clinical efficacy of various brands of beta-blocker in secondary prevention after a myocardial infarction (MI)...
  59. doi request reprint Differences between out-of-hospital cardiac arrest in residential and public locations and implications for public-access defibrillation
    Fredrik Folke
    Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark
    Circulation 122:623-30. 2010
    ..We examined whether residential OHCA areas suitable for placement of automated external defibrillators could be identified on the basis of demographic characteristics and characterized individuals with OHCA in residential locations...
  60. ncbi request reprint Vascular insulin response is preserved in non-diabetic patients with coronary artery disease, despite endothelial dysfunction
    Nikolaj Ihlemann
    Department of Cardiology, Bispebjerg University Hospital, Copenhagen, Denmark
    Scand Cardiovasc J 38:22-7. 2004
    ..Recently, it was suggested that a "vascular insulin resistance" could explain this association, causing endothelial dysfunction and hence atherosclerosis. We therefore studied the vascular insulin response in patients with CAD...
  61. ncbi request reprint Long-term compliance with beta-blockers, angiotensin-converting enzyme inhibitors, and statins after acute myocardial infarction
    Gunnar H Gislason
    Department of Cardiovascular Medicine, Bispebjerg University Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
    Eur Heart J 27:1153-8. 2006
    ..To study initiation, dosages, and compliance with beta-blockers, angiotensin-converting enzyme (ACE)-inhibitors, and statins in patients after acute myocardial infarction (AMI) and to identify likely targets for improvement...
  62. doi request reprint Evaluation of the CHADS2 risk score on short- and long-term all-cause and cardiovascular mortality after syncope
    Martin Huth Ruwald
    Department of Cardiology, Gentofte Hospital, Hellerup, Denmark
    Clin Cardiol 36:262-8. 2013
    ..Syncope risk stratification is difficult and has not been implemented clinically...
  63. ncbi request reprint The safety of amiodarone in patients with heart failure
    Christian Torp-Pedersen
    Department of Cardiology, Bispebjerg University Hospital, Copenhagen, Denmark
    J Card Fail 13:340-5. 2007
    ..Uncertainty persists about the safety and efficacy of amiodarone for the management of heart failure...
  64. doi request reprint Relation of body mass index to risk of stent thrombosis after percutaneous coronary intervention
    Michelle Schmiegelow
    Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
    Am J Cardiol 110:1592-7. 2012
    ..01 (CI 0.99 to 1.03) and 0.99 (CI 0.98 to 1.01) for each increase in kilograms per square meter of BMI, respectively. In conclusion, BMI was inversely correlated with risk of definite stent thrombosis after PCI irrespective of stent type...
  65. doi request reprint Importance and inter-relationship of tissue Doppler variables for predicting adverse outcomes in high-risk patients: an analysis of 388 diabetic patients referred for coronary angiography
    Charlotte Andersson
    Department of Cardiology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Eur Heart J Cardiovasc Imaging 13:643-9. 2012
    ..To investigate the relative importance of individual tissue Doppler imaging variables to predict adverse events in a high-risk population with diabetes, ischaemic heart disease, and/or systolic dysfunction...
  66. doi request reprint Increased short-term risk of thrombo-embolism or death after interruption of warfarin treatment in patients with atrial fibrillation
    Jakob Raunsø
    Department of Cardiology, Copenhagen University Hospital Gentofte, Post 67, Hellerup 2900, Denmark
    Eur Heart J 33:1886-92. 2012
    ..The purpose of this study was to assess the risk and timing of thrombo-embolism after warfarin treatment interruption...
  67. pmc Discontinuation of hormone replacement therapy after myocardial infarction and short term risk of adverse cardiovascular events: nationwide cohort study
    Ditte Marie Bretler
    Department of Cardiology, Copenhagen University Hospital Gentofte, Copenhagen, Denmark
    BMJ 344:e1802. 2012
    ..To assess the risk of adverse cardiovascular events in women who discontinue hormone replacement therapy after myocardial infarction compared with those who continue...
  68. pmc Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: nationwide propensity score matched study
    Mette Charlot
    Department of Cardiology, Copenhagen University Hospital Gentofte, Post 635, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    BMJ 342:d2690. 2011
    ..To examine the effect of proton pump inhibitors on adverse cardiovascular events in aspirin treated patients with first time myocardial infarction...
  69. ncbi request reprint Prevalence, prognostic significance, and treatment of atrial fibrillation in congestive heart failure with particular reference to the DIAMOND-CHF study
    Ole Dyg Pedersen
    Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
    Congest Heart Fail 9:333-40. 2003
    ..It is unknown whether one of these strategies is better than the other. In this review the authors discuss the prevalence, impact, and treatment of atrial fibrillation in heart failure patients...
  70. doi request reprint Atrial fibrillation in heart failure is associated with an increased risk of death only in patients with ischaemic heart disease
    Jakob Raunsø
    Department of Cardiology, Gentofte Hospital, Copenhagen University Hospital, Post 67, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Eur J Heart Fail 12:692-7. 2010
    ..In the present study, we investigated the prognostic impact of AF in a large population with HF of various aetiologies...
  71. ncbi request reprint Effect of dofetilide on QT dispersion and the prognostic implications of changes in QT dispersion for patients with congestive heart failure
    Bente Brendorp
    Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark
    Eur J Heart Fail 4:201-6. 2002
    ..Drug-induced changes in QT dispersion may be a way of detecting harmful repolarisation abnormalities for patients receiving antiarrhythmic drugs affecting ventricular repolarisation...
  72. ncbi request reprint Prehospital behaviour of patients admitted with acute coronary syndrome or witnessed cardiac arrest
    Michael Mundt Ottesen
    Department of Cardiology, University Hospital of Copenhagen County, Gentofte, Denmark
    Scand Cardiovasc J 37:141-8. 2003
    ..To study prehospital behaviour of patients admitted with acute coronary syndrome or witnessed cardiac arrest...
  73. doi request reprint Body mass index is closely correlated to incident diabetes in patients with heart failure or myocardial infarction
    Michelle Schmiegelow
    Department of Cardiology, Gentofte University Hospital, Niels Andersens Vej 65, Copenhagen, Denmark
    Eur J Cardiovasc Prev Rehabil 18:305-11. 2011
    ..Diabetes in patients with heart failure or myocardial infarction (MI) increases morbidity and mortality, but little is known about the impact of obesity on the risk of developing diabetes in these populations...
  74. doi request reprint Valproate attenuates the risk of myocardial infarction in patients with epilepsy: a nationwide cohort study
    Jonas Bjerring Olesen
    Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
    Pharmacoepidemiol Drug Saf 20:146-53. 2011
    ..Patients with epilepsy have increased risk of myocardial infarction (MI). Valproate can exert anti-atherosclerotic effects. We therefore examined the risk of MI in patients with epilepsy receiving valproate...
  75. ncbi request reprint Ambulatory arterial stiffness index predicts stroke in a general population
    Tine W Hansen
    Research Center for Prevention and Health, Copenhagen, Denmark
    J Hypertens 24:2247-53. 2006
    ..The ambulatory arterial stiffness index (AASI) can be computed from individual 24-h blood pressure recordings...
  76. doi request reprint Hospital admissions and pharmacotherapy before out-of-hospital cardiac arrest according to age
    Peter Weeke
    Department of Cardiology, Copenhagen University Hospital, Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Resuscitation 83:584-90. 2012
    ..We aimed to determine the specific type of healthcare contact shortly before out-of-hospital cardiac arrest (OHCA) across ages...
  77. doi request reprint Association of warfarin therapy duration after bioprosthetic aortic valve replacement with risk of mortality, thromboembolic complications, and bleeding
    Charlotte Mérie
    Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    JAMA 308:2118-25. 2012
    ..The need for anticoagulation after surgical aortic valve replacement (AVR) with biological prostheses is not well examined...
  78. pmc Incidence of atrial fibrillation in patients with either heart failure or acute myocardial infarction and left ventricular dysfunction: a cohort study
    Michelle D Schmiegelow
    Department of Cardiology, Gentofte University Hospital, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    BMC Cardiovasc Disord 11:19. 2011
    ..Patients were with and without treatment with the class III antiarrhythmic drug dofetilide over 36 months...
  79. doi request reprint Long-term impact of diabetes in patients hospitalized with ischemic and non-ischemic heart failure
    Charlotte Andersson
    Department of Cardiology, Gentofte University Hospital, Denmark
    Scand Cardiovasc J 44:37-44. 2010
    ..Diabetes mellitus (DM) in combination with heart failure (HF) is associated with a high risk of death, but it is uncertain whether the prognosis differs in ischemic and non-ischemic HF groups...
  80. ncbi request reprint A meta-analysis of the effect of angiotensin-converting enzyme inhibitors on functional capacity in patients with symptomatic left ventricular systolic dysfunction
    Jawdat Abdulla
    Department of Cardiology P, Gentofte University Hospital, Niels Andersensvej 65, DK 2990 Hellerup, Denmark
    Eur J Heart Fail 6:927-35. 2004
    ..To determine by meta-analysis whether angiotensin-converting enzyme (ACE) inhibitors improve exercise tolerance in patients with symptomatic left ventricular systolic dysfunction (LVSD)...
  81. doi request reprint Metformin is associated with improved left ventricular diastolic function measured by tissue Doppler imaging in patients with diabetes
    Charlotte Andersson
    Department of Cardiology, Copenhagen University Hospital, Gentofte, Copenhagen, Denmark
    Eur J Endocrinol 163:593-9. 2010
    ..To examine the association between selected glucose-lowering medications and left ventricular (LV) diastolic function in patients with diabetes...
  82. ncbi request reprint Methods of assessing the functional status of patients with left ventricular systolic dysfunction in interventional studies: can brain natriuretic peptide measurement be used as surrogate for the traditional methods?
    Jawdat Abdulla
    Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
    Cardiovasc Drugs Ther 18:219-24. 2004
    ..To review whether brain natriuretic peptides (BNP) can be used as a surrogate for the traditional methods of assessing functional status in interventional studies of patients with left ventricular systolic dysfunction (LVSD)...
  83. ncbi request reprint Female sex is associated with a better long-term survival in patients hospitalized with congestive heart failure
    Finn Gustafsson
    Department of Cardiology Y, Bispebjerg University Hospital, Copenhagen, Denmark
    Eur Heart J 25:129-35. 2004
    ..The aim of this study was determine whether mortality risk in women and men hospitalized with congestive heart failure is different...
  84. ncbi request reprint The reliability of echocardiographic left ventricular wall motion index to identify high-risk patients for multicenter studies
    Gunnar H Gislason
    Department of Cardiovascular Medicine, Bispebjerg University Hospital, Copenhagen, Denmark
    Echocardiography 23:1-6. 2006
    ..To study whether the use of echocardiographic left ventricular (LV) wall motion index (WMI) is a dependable parameter for identifying patients with LV dysfunction to be enrolled in multicenter trials...
  85. ncbi request reprint Persistent use of evidence-based pharmacotherapy in heart failure is associated with improved outcomes
    Gunnar H Gislason
    Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
    Circulation 116:737-44. 2007
    ..We studied initiation and persistence of evidence-based pharmacotherapy in 107,092 patients discharged after first hospitalization for heart failure in Denmark from 1995 to 2004...
  86. pmc Different angiotensin-converting enzyme inhibitors have similar clinical efficacy after myocardial infarction
    Morten L Hansen
    Department of Cardiovascular Medicine, Bispebjerg University Hospital, Copenhagen, Denmark
    Br J Clin Pharmacol 65:217-23. 2008
    ..Therefore, for long-term benefits for patients who need treatment with an ACE inhibitor, a focus of treatment at the recommended dosage is most important and not which ACE inhibitor is used...
  87. ncbi request reprint Congestive heart failure with preserved left ventricular systolic function after acute myocardial infarction: clinical and prognostic implications
    Jacob Eifer Møller
    Department of Cardiology, Odense University Hospital, Odense, Denmark
    Eur J Heart Fail 5:811-9. 2003
    ..To characterise the prevalence, in-hospital complications, management, and long-term outcome of patients with congestive heart failure but preserved left ventricular systolic function after acute myocardial infarction...
  88. doi request reprint The value of the CHA2DS2-VASc score for refining stroke risk stratification in patients with atrial fibrillation with a CHADS2 score 0-1: a nationwide cohort study
    Jonas Bjerring Olesen
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    Thromb Haemost 107:1172-9. 2012
    ..Use of the CHA2DS2-VASc score would significantly improve classification of AF patients at low and intermediate risk of stroke, compared to the commonly used CHADS2 score...
  89. pmc Diabetes is associated with impaired myocardial performance in patients without significant coronary artery disease
    Charlotte Andersson
    Department of Cardiology, Gentofte Hospital, University of Copenhagen, Denmark
    Cardiovasc Diabetol 9:3. 2010
    ..Echocardiographic tissue Doppler imaging was therefore performed in DM patients without significant CAD to examine whether DM per se influenced cardiac function...
  90. ncbi request reprint Hospital variation in use of secondary preventive medicine after discharge for first acute myocardial infarction during 1995-2004
    Søren Rasmussen
    National Institute of Public Health, Copenhagen, Denmark
    Med Care 46:70-7. 2008
    ..To examine temporal trends in hospital use of secondary preventive medicine after discharge for first acute myocardial infarction (AMI) in Denmark...
  91. ncbi request reprint The long-term impact of the angiotensin-converting enzyme inhibitor trandolapril on mortality and hospital admissions in patients with left ventricular dysfunction after a myocardial infarction: follow-up to 12 years
    Pernille Buch
    Department of Cardiology, Bispebjerg University Hospital, Bispebjerg Bakke 23, Building 40, DK 2400 Copenhagen NV, Denmark
    Eur Heart J 26:145-52. 2005
    ..To investigate the long-term benefits of treatment with angiotensin-converting enzyme (ACE)-inhibitors in patients with myocardial infarction (MI) and left ventricular dysfunction (LVD)...
  92. ncbi request reprint Ambulatory blood pressure and mortality: a population-based study
    Tine Willum Hansen
    Research Center for Prevention and Health, Glostrup University Hospital, Copenhagen, Denmark
    Hypertension 45:499-504. 2005
    ..In conclusion, ambulatory blood pressure provided prognostic information on mortality above and beyond that of office blood pressure...
  93. ncbi request reprint Does conversion and prevention of atrial fibrillation enhance survival in patients with left ventricular dysfunction? Evidence from the Danish Investigations of Arrhythmia and Mortality ON Dofetilide/(DIAMOND) study
    Ole Dyg Pedersen
    Department of Cardiology P, Gentofte University Hospital, 2900 Hellerup, Denmark
    Card Electrophysiol Rev 7:220-4. 2003
    ..The present study investigated the potential of dofetilide to restore and maintain sinus rhythm in patients with left ventricular dysfunction, which might reduce mortality and hospitalizations...
  94. ncbi request reprint Quinapril treatment increases insulin-stimulated endothelial function and adiponectin gene expression in patients with type 2 diabetes
    Thomas S Hermann
    Department of Cardiology Y, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, Denmark
    J Clin Endocrinol Metab 91:1001-8. 2006
    ....
  95. ncbi request reprint Right ventricular dysfunction as an independent predictor of short- and long-term mortality in patients with heart failure
    Jesper Kjaergaard
    Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, DK 2100 Copenhagen, Denmark
    Eur J Heart Fail 9:610-6. 2007
    ..Tricuspid annular plane systolic excursion (TAPSE) is a simple echocardiographic measure of RV ejection fraction, but may be affected by co-existing chronic obstructive pulmonary disease (COPD)...
  96. pmc Psoriasis carries an increased risk of venous thromboembolism: a Danish nationwide cohort study
    Ole Ahlehoff
    Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
    PLoS ONE 6:e18125. 2011
    ..Venous thromboembolism (VTE) is potentially lethal and shares risk factors with psoriasis, but the risk of VTE associated with psoriasis is unknown. The present study investigated the potential association between psoriasis and VTE...
  97. doi request reprint Cause-specific cardiovascular risk associated with nonsteroidal antiinflammatory drugs among healthy individuals
    Emil Loldrup Fosbøl
    Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
    Circ Cardiovasc Qual Outcomes 3:395-405. 2010
    ..Studies have raised concern on the cardiovascular safety of nonsteroidal antiinflammatory drugs (NSAIDs). We studied safety of NSAID therapy in a nationwide cohort of healthy individuals...
  98. ncbi request reprint Prolonged local forearm hyperinsulinemia induces sustained enhancement of nitric oxide-dependent vasodilation in healthy subjects
    Thomas S Hermann
    Department of Cardiology Y, Bispebjerg University Hospital, Copenhagen NV, Denmark
    Endothelium 11:231-9. 2004
    ..Four hours of local forearm hyperinsulinemia causes a sustained increase in endothelium dependent vasodilation in resistance vessels, which is mediated by NO...
  99. ncbi request reprint Prognostic importance of complete atrioventricular block complicating acute myocardial infarction
    Mark Aplin
    Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Am J Cardiol 92:853-6. 2003
    ..This report also outlines an important distinction between atrioventricular block in the setting of anterior and inferior wall acute myocardial infarction, with profound clinical and prognostic implications...
  100. doi request reprint Wall motion index, estimated glomerular filtration rate and mortality risk in patients with heart failure or myocardial infarction: a pooled analysis of 18,010 patients
    Morten Schou
    Department of Cardiology, The Heart Centre, Rigshospitalet University Hospital, DK 2100 Copenhagen O, Denmark
    Eur J Heart Fail 10:682-8. 2008
    ....
  101. ncbi request reprint Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure
    Finn Gustafsson
    Department of Cardiology, The Heart Centre, University Hospital of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Eur Heart J 25:1711-7. 2004
    ..To describe the association between age and risk factors in patients hospitalised with congestive heart failure (CHF) and to determine the effect of age on mortality...