S F Thomsen

Summary

Affiliation: Bispebjerg Hospital
Country: Denmark

Publications

  1. pmc Principal components analysis of atopy-related traits in a random sample of children
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, 2400 Copenhagen, Denmark
    ISRN Allergy 2011:170989. 2011
  2. pmc Predictors of Serum Total IgE in a Random Sample of 7-17 Year Old Children
    Sofie Strømgaard
    Department of Respiratory Medicine, Bispebjerg Hospital, 2400 Copenhagen, Denmark
    ISRN Allergy 2011:169859. 2011
  3. pmc Urticaria in monozygotic and dizygotic twins
    Simon Francis Thomsen
    Department of Dermato Allergology Gentofte Hospital 2900 Hellerup, Denmark
    J Allergy (Cairo) 2012:125367. 2012
  4. pmc Omalizumab for chronic urticaria: a case series and overview of the literature
    Ilya Ivyanskiy
    Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark
    Case Rep Dermatol 4:19-26. 2012
  5. doi request reprint A study of asthma severity in adult twins
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Clin Respir J 6:228-37. 2012
  6. doi request reprint Intake of paracetamol and risk of asthma in adults
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    J Asthma 45:675-6. 2008
  7. ncbi request reprint Genetic and environmental contributions to hay fever among young adult twins
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, DK 2400 Copenhagen NV, and The Danish Twin Registry, University of Southern Denmark, Odense, Denmark
    Respir Med 100:2177-82. 2006
  8. doi request reprint A note on twin-singleton differences in asthma
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Twin Res Hum Genet 11:161-4. 2008
  9. doi request reprint Genetic influence on the age at onset of asthma: a twin study
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    J Allergy Clin Immunol 126:626-30. 2010
  10. doi request reprint Exploring the association between severe respiratory syncytial virus infection and asthma: a registry-based twin study
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen NV, Denmark
    Am J Respir Crit Care Med 179:1091-7. 2009

Collaborators

Detail Information

Publications43

  1. pmc Principal components analysis of atopy-related traits in a random sample of children
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, 2400 Copenhagen, Denmark
    ISRN Allergy 2011:170989. 2011
    ..Conclusion. Asthma, hay fever, and atopic dermatitis are characterised by different sets of biomarkers suggestive of a high degree of heterogeneity within the atopic syndrome...
  2. pmc Predictors of Serum Total IgE in a Random Sample of 7-17 Year Old Children
    Sofie Strømgaard
    Department of Respiratory Medicine, Bispebjerg Hospital, 2400 Copenhagen, Denmark
    ISRN Allergy 2011:169859. 2011
    ..This study showed a strong positive relationship between markers of the atopic syndrome and serum total IgE levels in children. In contrast to some earlier studies, we did not find a significant relation between smoking status and IgE...
  3. pmc Urticaria in monozygotic and dizygotic twins
    Simon Francis Thomsen
    Department of Dermato Allergology Gentofte Hospital 2900 Hellerup, Denmark
    J Allergy (Cairo) 2012:125367. 2012
    ..01-0.89), P = 0.040. Conclusions. Susceptibility to urticaria is partly determined by genetic factors. Urticaria is more common in women, and in subjects with hay fever and atopic dermatitis, and shares genetic variance with hay fever...
  4. pmc Omalizumab for chronic urticaria: a case series and overview of the literature
    Ilya Ivyanskiy
    Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark
    Case Rep Dermatol 4:19-26. 2012
    ..The collective evidence points to omalizumab as a safe and effective treatment option for patients with chronic urticaria who do not sufficiently respond to standard therapy as recommended by existing guidelines...
  5. doi request reprint A study of asthma severity in adult twins
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Clin Respir J 6:228-37. 2012
    ..The tendency to develop asthma runs in families, but whether the severity of asthma symptoms is inherited is not known...
  6. doi request reprint Intake of paracetamol and risk of asthma in adults
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    J Asthma 45:675-6. 2008
    ..16 (1.03-4.53), p = 0.041. Frequent intake of paracetamol is an independent risk factor for adult-onset asthma...
  7. ncbi request reprint Genetic and environmental contributions to hay fever among young adult twins
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, DK 2400 Copenhagen NV, and The Danish Twin Registry, University of Southern Denmark, Odense, Denmark
    Respir Med 100:2177-82. 2006
    ..The susceptibility to develop hay fever is putatively the result both of genetic and environmental causes. We estimated the significance and magnitude of genetic and environmental contributions to hay fever among young adult twins...
  8. doi request reprint A note on twin-singleton differences in asthma
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Twin Res Hum Genet 11:161-4. 2008
    ..We review some of the possible explanations for these findings and conclude that results from twin studies of asthma can be extrapolated to the general population...
  9. doi request reprint Genetic influence on the age at onset of asthma: a twin study
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    J Allergy Clin Immunol 126:626-30. 2010
    ..Although the genetics of asthma susceptibility have been frequently explored, little is known about genetic factors that influence the age at onset of asthma...
  10. doi request reprint Exploring the association between severe respiratory syncytial virus infection and asthma: a registry-based twin study
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen NV, Denmark
    Am J Respir Crit Care Med 179:1091-7. 2009
    ..Severe respiratory syncytial virus (RSV) infection is associated with asthma but the nature of this association is imperfectly understood...
  11. ncbi request reprint [Diagnostics and treatment of pruritus ani]
    Simon Francis Thomsen
    Kirurgisk gastroenterologisk afdeling, Bispebjerg Hospital, København NV
    Ugeskr Laeger 171:3791-4. 2009
    ..Causes and treatment are reviewed, and it is concluded that the condition, even in its chronic refractory form, has a favourable prognosis...
  12. doi request reprint Estimates of asthma heritability in a large twin sample
    S F Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Clin Exp Allergy 40:1054-61. 2010
    ..Asthma is a complex disease characterized by symptoms of wheezing, shortness of breath, chest tightness, and cough...
  13. doi request reprint Risk of asthma in adult twins with type 2 diabetes and increased body mass index
    S F Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Allergy 66:562-8. 2011
    ..To examine the relationship between asthma, type 2 diabetes and increased body mass index (BMI) in adult twins...
  14. doi request reprint Relationship between type 1 diabetes and atopic diseases in a twin population
    S F Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Allergy 66:645-7. 2011
    ..To study the association between type 1 diabetes and atopic diseases in a twin population...
  15. doi request reprint Increase in the heritability of asthma from 1994 to 2003 among adolescent twins
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, 2400 Copenhagen NV, Denmark
    Respir Med 105:1147-52. 2011
    ..We examined whether the extent to which genetic and environmental factors influence susceptibility to asthma has changed between 1994 and 2003...
  16. doi request reprint Etiological relationships in atopy: a review of twin studies
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Twin Res Hum Genet 11:112-20. 2008
    ..We emphasize that multivariate methods applied to twin studies, especially when genetic marker information is available, provide a valuable framework within which complex etiological mechanisms underlying atopy can be disentangled...
  17. doi request reprint Increased concordance of severe respiratory syncytial virus infection in identical twins
    Simon Francis Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Bispebjerg Bakke 23, Building 60 DK 2400 Copenhagen NV, Denmark
    Pediatrics 121:493-6. 2008
    ..We estimated differences in the severity of respiratory syncytial virus infection attributable to genetic and environmental factors...
  18. ncbi request reprint The incidence of asthma in young adults
    Simon F Thomsen
    Department of Internal Medicine I, Bispebjerg Hospital, DK 2400 Copenhagen NV, Denmark
    Chest 127:1928-34. 2005
    ..The objectives of this study were to determine the incidence of asthma and to establish the risk factors for the development of asthma in subjects who were 12 to 41 years old over an 8-year period...
  19. ncbi request reprint Skin test reactivity among Danish children measured 15 years apart
    Simon Francis Thomsen
    Department of Internal Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    J Asthma 43:151-3. 2006
    ..Knowledge of secular trends in the prevalence of allergy among children stems in large part from questionnaire surveys, whereas repeated cross-sectional studies using objective markers of atopic sensitization are sparse...
  20. ncbi request reprint Early life exposures and risk of atopy among Danish children
    Simon F Thomsen
    Department of Internal Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Allergy Asthma Proc 27:110-4. 2006
    ..Parental knowledge of atopic heredity significantly influences smoking and breast-feeding habits...
  21. ncbi request reprint Multivariate genetic analysis of atopy phenotypes in a selected sample of twins
    S F Thomsen
    Department of Internal Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Clin Exp Allergy 36:1382-90. 2006
    ..Atopic traits often co-occur and this can potentially be caused by common aetiological relationships between traits, i.e. a common genetic or a common environmental background...
  22. ncbi request reprint Findings on the atopic triad from a Danish twin registry
    S F Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Int J Tuberc Lung Dis 10:1268-72. 2006
    ..To estimate to what extent the same genetic and environmental risk factors influence asthma, hay fever and eczema...
  23. ncbi request reprint Change in prevalence of asthma in Danish children and adolescents
    Simon F Thomsen
    Department of Internal Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Ann Allergy Asthma Immunol 92:506-11. 2004
    ..There is evidence suggesting that the prevalence of asthma has increased, especially in industrialized countries...
  24. ncbi request reprint Importance of genetic factors in the etiology of atopic dermatitis: a twin study
    Simon F Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Allergy Asthma Proc 28:535-9. 2007
    ..98). The estimates were adjusted for age. The susceptibility to develop atopic dermatitis is attributable to mainly genetic differences between people. However, differences in environmental exposures also are of importance...
  25. ncbi request reprint Association between obesity and asthma in a twin cohort
    S F Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Allergy 62:1199-204. 2007
    ..Obesity is linked to asthma in a yet poorly understood manner. We examined the relationship between obesity and asthma in a population-based sample of twins...
  26. ncbi request reprint Differences between allergic and nonallergic rhinitis in a large sample of adolescents and adults
    E Mølgaard
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Allergy 62:1033-7. 2007
    ..The aim of this study was to describe differences between allergic rhinitis (AR) and nonallergic rhinitis (NAR) in a large community-based sample of Danish adolescents and adults...
  27. ncbi request reprint Risk factors for asthma in young adults: a co-twin control study
    S F Thomsen
    Department of Internal Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Allergy 61:229-33. 2006
    ..The liability to asthma is influenced both by genetic and environmental factors. The objective of this study was to identify risk factors for asthma in young adult twin pairs during an 8-year period...
  28. doi request reprint Heredity in sarcoidosis: a registry-based twin study
    A Sverrild
    Department of Respiratory Medicine, Bispebjerg Hospital, DK 2400 Copenhagen NV, Denmark
    Thorax 63:894-6. 2008
    ..This paper reports twin concordance and heritability estimates of sarcoidosis in order to assess the overall contribution of genetic factors to the disease susceptibility...
  29. doi request reprint Rhinitis: a complication to asthma
    J W Hansen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark
    Allergy 65:883-8. 2010
    ..We studied disease severity, airway responsiveness, atopy, quality of life and treatment in subjects with both asthma and rhinitis compared to patients with asthma or rhinitis alone...
  30. doi request reprint A quantitative genetic analysis of intermediate asthma phenotypes
    S F Thomsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Allergy 64:427-30. 2009
    ..To study the relative contribution of genetic and environmental factors to the correlation between exhaled nitric oxide (FeNO), airway responsiveness, airway obstruction, and serum total immunoglobulin E (IgE)...
  31. doi request reprint The bronchial response to mannitol is attenuated by a previous methacholine test: but not vice versa
    E Gade
    Department of Respiratory Medicine, Copenhagen University Hospital, Bispebjerg Hospital, Copenhagen, Denmark
    Clin Exp Allergy 39:966-71. 2009
    ..To examine the airway response to inhaled mannitol performed before or after a methacholine challenge test in a group of asthmatics with different levels of disease...
  32. ncbi request reprint A 3-year longitudinal study of asthma quality of life in undiagnosed and diagnosed asthma patients
    V Backer
    Respiratory and Allergy Research Unit, Department of Respiratory Medicine, University Hospital of Copenhagen, HS Bispebjerg Hospital, 2400 Copenhagen NV, Denmark
    Int J Tuberc Lung Dis 11:463-9. 2007
    ....
  33. ncbi request reprint Response to mannitol in asymptomatic subjects with airway hyper-responsiveness to methacholine
    C Porsbjerg
    Respiratory Research Unit, Bispebjerg Hospital University of Copenhagen, Copenhagen NV, Denmark
    Clin Exp Allergy 37:22-8. 2007
    ..Mannitol is an osmotic stimulus that acts indirectly to cause airway narrowing by release of endogenous bronchoconstricting mediators...
  34. doi request reprint Change in prevalence of atopic dermatitis between 1986 and 2001 among children
    Lise Stensen
    Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Allergy Asthma Proc 29:392-6. 2008
    ..In addition, we found that AD was significantly associated with AHR, rhinitis, and elevated levels of IgE, supporting the idea of the atopic triad...
  35. ncbi request reprint Smoking and skin disease
    S F Thomsen
    Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark
    Skin Therapy Lett 15:4-7. 2010
    ..Most likely, alteration of inflammatory cell function and extracellular matrix turnover caused by smoking-induced oxidative stress are involved in the pathophysiologic mechanisms...
  36. doi request reprint Birth weight and risk of asthma in 3-9-year-old twins: exploring the fetal origins hypothesis
    Karin Kindlund
    Department of Respiratory Medicine, Bispebjerg Hospital, DK 2400 Copenhagen NV, Denmark
    Thorax 65:146-9. 2010
    ..To examine the relationship between birth weight and risk of asthma in a population of twins...
  37. ncbi request reprint Lung function in Greenlandic and Danish children and adolescents
    Tyra Grove Krause
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Artillertivej 5, DK 2300 Copenhagen S, Denmark
    Respir Med 99:363-71. 2005
    ..However, our finding that Greenlanders living in settlements had the highest lung function level also suggests a possible role of factors in the traditional Greenlandic lifestyle...
  38. ncbi request reprint Season of birth and risk of atopic disease among children and adolescents
    Thomas Bøllingtoft Knudsen
    Department of Respiratory Medicine, Bispebjerg Hospital, Denmark
    J Asthma 44:257-60. 2007
    ..Season of birth (SOB) has been regarded as a risk factor for atopy. The aim of this study was to explore the relationship between season of birth (SOB) and later development of atopic disease in children and adolescents...
  39. ncbi request reprint Increase in the prevalence of rhinitis among Danish children from 1986 to 2001
    Kåre Håkansson
    Department of Respiratory Medicine, Bispebjerg Hospital, Denmark
    Pediatr Allergy Immunol 18:154-9. 2007
    ..These results underline the importance of using objective measurements such as skin test reactivity when estimating time trends in the prevalence of allergic airways disease, as clinical interviews alone can be misleading...
  40. ncbi request reprint [Exercise-induced inspiratory stridor. An important differential diagnosis of exercise-induced asthma]
    Pernille Christensen
    Bispebjerg Hospital, Lungemedicinsk Forskningsenhed, Lunge medicinsk Klinik L, København NV
    Ugeskr Laeger 169:4047-50. 2007
    ..The pathophysiology, the pathogenesis, and the treatment of the condition are not yet clarified. At present, a population-based study is being conducted in order to address these points...
  41. ncbi request reprint [Chronic obstructive pulmonary disease and genetics]
    Truls Ingebrigtsen
    Bispebjerg Hospital, Lungemedicinsk Forskningsenhed, Lungemedicinsk afdeling L
    Ugeskr Laeger 170:2971-3. 2008
    ..It is therefore important to measure phenotypes and to perform genome-wide scans of COPD patients in order to unravel the contribution of the COPD susceptibility genes...