Research Topics
| Gunnar H GislasonSummaryAffiliation: Bispebjerg University Hospital Country: Denmark Publications
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Detail Information
Publications
Increased mortality and cardiovascular morbidity associated with use of nonsteroidal anti-inflammatory drugs in chronic heart failureGunnar H Gislason
Department of Cardiology, Gentofte University Hospital, Niels Andersens Vej 65, 2900 Hellerup, Denmark
Arch Intern Med 169:141-9. 2009..We studied the risk of death and hospitalization because of acute myocardial infarction and heart failure (HF) associated with use of NSAIDs in an unselected cohort of patients with HF...
Nationwide trends in the prescription of beta-blockers and angiotensin-converting enzyme inhibitors after myocardial infarction in Denmark, 1995-2002Gunnar H Gislason
Department of Cardiovascular Medicine, Bispebjerg University Hospital, Copenhagen, Denmark
Scand Cardiovasc J 39:42-9. 2005..To study the use of beta-blockers and angiotensin-converting enzyme (ACE) inhibitors after acute myocardial infarction (AMI) in Denmark from 1995 to 2002...
Long-term compliance with beta-blockers, angiotensin-converting enzyme inhibitors, and statins after acute myocardial infarctionGunnar H Gislason
Department of Cardiovascular Medicine, Bispebjerg University Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
Eur Heart J 27:1153-8. 2006..To study initiation, dosages, and compliance with beta-blockers, angiotensin-converting enzyme (ACE)-inhibitors, and statins in patients after acute myocardial infarction (AMI) and to identify likely targets for improvement...
The reliability of echocardiographic left ventricular wall motion index to identify high-risk patients for multicenter studiesGunnar H Gislason
Department of Cardiovascular Medicine, Bispebjerg University Hospital, Copenhagen, Denmark
Echocardiography 23:1-6. 2006..To study whether the use of echocardiographic left ventricular (LV) wall motion index (WMI) is a dependable parameter for identifying patients with LV dysfunction to be enrolled in multicenter trials...
Risk of death or reinfarction associated with the use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs after acute myocardial infarctionGunnar H Gislason
Department of Cardiology, Gentofte University Hospital, DK 2900 Hellerup, Denmark
Circulation 113:2906-13. 2006..We analyzed the risk of rehospitalization for acute myocardial infarction (MI) and death related to the use of NSAIDs including selective COX-2 inhibitors in patients with prior MI...
Persistent use of evidence-based pharmacotherapy in heart failure is associated with improved outcomesGunnar H Gislason
Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
Circulation 116:737-44. 2007..We studied initiation and persistence of evidence-based pharmacotherapy in 107,092 patients discharged after first hospitalization for heart failure in Denmark from 1995 to 2004...
Renal function at the time of a myocardial infarction maintains prognostic value for more than 10 yearsThomas Kümler
Dept of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark
BMC Cardiovasc Disord 11:37. 2011..We examined the importance of renal function by estimated GFR (eGFR) and se-creatinine as an independent long-term prognostic factor...
Calcium-channel blockers do not alter the clinical efficacy of clopidogrel after myocardial infarction: a nationwide cohort studyJonas B Olesen
Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
J Am Coll Cardiol 57:409-17. 2011..The purpose of this study was to determine the risk of adverse cardiovascular events associated with concomitant use of clopidogrel and calcium-channel blockers (CCBs) in patients with myocardial infarction (MI)...
Antiarrhythmic therapy and risk of death in patients with atrial fibrillation: a nationwide studySøren Skøtt Andersen
Department of Cardiology, Gentofte University Hospital, Niels Andersens Vej 65, Hellerup, Copenhagen DK 2900, Denmark
Europace 11:886-91. 2009..To examine the risk of death associated with antiarrhythmic drug (AAD) therapy in a nationwide unselected cohort of patients with atrial fibrillation (AF)...
Clopidogrel discontinuation after myocardial infarction and risk of thrombosis: a nationwide cohort studyMette Charlot
Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
Eur Heart J 33:2527-34. 2012..We analysed the risk of adverse cardiovascular outcomes after discontinuation of 12 months of clopidogrel treatment...
Efficacy of post-operative clopidogrel treatment in patients revascularized with coronary artery bypass grafting after myocardial infarctionRikke Sørensen
Department of Cardiology, Copenhagen University Hospital Gentofte, Copenhagen, Denmark
J Am Coll Cardiol 57:1202-9. 2011..The objective of this study was to examine the clinical efficacy of clopidogrel treatment on death and recurrent myocardial infarction (MI) among MI patients revascularized by coronary artery bypass graft surgery (CABG)...
Temporal trends in the initiation of glucose-lowering medications after a first-time myocardial infarction - a nationwide study between 1997 and 2006Mette L Norgaard
Department of Cardiology, University Hospital of Copenhagen, Gentofte, Denmark
Cardiovasc Diabetol 10:5. 2011..The aim of the study was to investigate temporal trends in the initiation of GLM among patients discharged after first-time MI...
Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillationMorten L Hansen
Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65 2900, Hellerup, Copenhagen, Denmark
Arch Intern Med 170:1433-41. 2010..Patients with atrial fibrillation (AF) often require anticoagulation and platelet inhibition, but data are limited on the bleeding risk of combination therapy...
Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort studyAnne Marie Schjerning Olsen
Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark
Circulation 123:2226-35. 2011..We therefore studied the duration of NSAID treatment and cardiovascular risk in a nationwide cohort of patients with prior myocardial infarction (MI)...
Diabetes patients requiring glucose-lowering therapy and nondiabetics with a prior myocardial infarction carry the same cardiovascular risk: a population study of 3.3 million peopleTina Ken Schramm
Department of Cardiology, Gentofte University Hospital, Niels Andersens Vej 65, DK 2900, Hellerup, Denmark
Circulation 117:1945-54. 2008..Previous studies reveal major differences in the estimated cardiovascular risk in diabetes mellitus, including uncertainty about the risk in young patients. Therefore, large studies of well-defined populations are needed...
Use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs in high doses increases mortality and risk of reinfarction in patients with prior myocardial infarctionRikke Sørensen
Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
J Cardiovasc Nurs 23:14-9. 2008..Selective COX-2 inhibitors in all dosages and nonselective NSAIDs in high dosages should be used with particular caution in patients with a prior MI...
Mortality and reinfarction among patients using different beta-blockers for secondary prevention after a myocardial infarctionSøren Skøtt Andersen
Department of Cardiology, Gentofte University Hospital, Niels Andersens Vej 65, Copenhagen, Denmark
Cardiology 112:144-50. 2009..To study differences in the clinical efficacy of various brands of beta-blocker in secondary prevention after a myocardial infarction (MI)...
Long-term cardiovascular risk of nonsteroidal anti-inflammatory drug use according to time passed after first-time myocardial infarction: a nationwide cohort studyAnne Marie Schjerning Olsen
Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
Circulation 126:1955-63. 2012..We analyzed whether the cardiovascular risk associated with using nonsteroidal anti-inflammatory drugs (NSAIDs) was associated with the time elapsed following first-time MI...
Effects of oral glucose-lowering drugs on long term outcomes in patients with diabetes mellitus following myocardial infarction not treated with emergent percutaneous coronary intervention--a retrospective nationwide cohort studyCasper H Jørgensen
Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
Cardiovasc Diabetol 9:54. 2010....
The pattern of use of non-steroidal anti-inflammatory drugs (NSAIDs) from 1997 to 2005: a nationwide study on 4.6 million peopleEmil Loldrup Fosbøl
Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
Pharmacoepidemiol Drug Saf 17:822-33. 2008..To describe the nationwide pattern of use of non-steroidal anti-inflammatory drugs (NSAIDs) in the Danish population...
Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry dataRikke Sørensen
Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark
Lancet 374:1967-74. 2009..However, data for the safety of combinations are sparse. We examined the risk of hospital admission for bleeding associated with different antithrombotic regimens...
Prognosis in heart failure and the value of {beta}-blockers are altered by the use of antidepressants and depend on the type of antidepressants usedEmil Loldrup Fosbøl
Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
Circ Heart Fail 2:582-90. 2009..Guidelines recommend use of selective serotonin reuptake inhibitors (SSRIs), but knowledge of the prognostic effect of different classes of antidepressants is sparse...
Relation of body mass index to risk of stent thrombosis after percutaneous coronary interventionMichelle Schmiegelow
Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
Am J Cardiol 110:1592-7. 2012..01 (CI 0.99 to 1.03) and 0.99 (CI 0.98 to 1.01) for each increase in kilograms per square meter of BMI, respectively. In conclusion, BMI was inversely correlated with risk of definite stent thrombosis after PCI irrespective of stent type...
Atrial fibrillation pharmacotherapy after hospital discharge between 1995 and 2004: a shift towards beta-blockersMorten Lock Hansen
Department of Cardiology, Bispebjerg University Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen, Denmark
Europace 10:395-402. 2008..To study evolvement in pharmacotherapy of atrial fibrillation from 1995 to 2004...
Heart failure severity, as determined by loop diuretic dosages, predicts the risk of developing diabetes after myocardial infarction: a nationwide cohort studyCharlotte Andersson
Department of Cardiology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, DK 2900 Hellerup, Denmark
Eur J Heart Fail 12:1333-8. 2010..The aim of the present study was to investigate the relationship between HF severity and risk of developing diabetes in a nationwide cohort of patients with myocardial infarction (MI)...
Different angiotensin-converting enzyme inhibitors have similar clinical efficacy after myocardial infarctionMorten L Hansen
Department of Cardiovascular Medicine, Bispebjerg University Hospital, Copenhagen, Denmark
Br J Clin Pharmacol 65:217-23. 2008..Therefore, for long-term benefits for patients who need treatment with an ACE inhibitor, a focus of treatment at the recommended dosage is most important and not which ACE inhibitor is used...
Importance and inter-relationship of tissue Doppler variables for predicting adverse outcomes in high-risk patients: an analysis of 388 diabetic patients referred for coronary angiographyCharlotte Andersson
Department of Cardiology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark
Eur Heart J Cardiovasc Imaging 13:643-9. 2012..To investigate the relative importance of individual tissue Doppler imaging variables to predict adverse events in a high-risk population with diabetes, ischaemic heart disease, and/or systolic dysfunction...
Psoriasis and risk of atrial fibrillation and ischaemic stroke: a Danish Nationwide Cohort StudyOle Ahlehoff
Department of Cardiology, Copenhagen University Hospital Gentofte, DK 2900 Hellerup, Denmark
Eur Heart J 33:2054-64. 2012..Psoriasis is a chronic inflammatory disease and inflammation contributes to the pathogenesis of atrial fibrillation (AF) and ischaemic stroke. We therefore investigated the risk of these endpoints in patients with psoriasis...
Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: nationwide propensity score matched studyMette Charlot
Department of Cardiology, Copenhagen University Hospital Gentofte, Post 635, Niels Andersens Vej 65, 2900 Hellerup, Denmark
BMJ 342:d2690. 2011..04, 0.79 to 1.38; P=0.78). Conclusion In aspirin treated patients with first time myocardial infarction, treatment with proton pump inhibitors was associated with an increased risk of adverse cardiovascular events...
Statin use after acute myocardial infarction: a nationwide study in DenmarkJeppe N Rasmussen
National Institute of Public Health, Copenhagen, Denmark
Br J Clin Pharmacol 60:150-8. 2005..To study outpatient statin use after first acute myocardial infarction (AMI) in Denmark between 1995 and 2002 and to determine the predictors of statin use...
The prognostic importance of a history of hypertension in patients with symptomatic heart failure is substantially worsened by a short mitral inflow deceleration timeCharlotte Andersson
Department of Cardiology, Gentofte Hospital, Hellerup, Denmark
BMC Cardiovasc Disord 12:30. 2012..Hypertension is a common comorbidity in patients with heart failure and may contribute to development and course of disease, but the importance of a history of hypertension in patients with prevalent heart failure remains uncertain...
Comparable long-term mortality risk associated with individual sulfonylureas in diabetes patients with heart failureCharlotte Andersson
Department of Cardiology, Copenhagen University Hospital, Gentofte, Hellerup, Denmark
Diabetes Res Clin Pract 94:119-25. 2011..The aim was to investigate the outcomes of individual sulfonylureas in patients with heart failure (HF)...
Cause-specific cardiovascular risk associated with nonsteroidal antiinflammatory drugs among healthy individualsEmil Loldrup Fosbøl
Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
Circ Cardiovasc Qual Outcomes 3:395-405. 2010..Studies have raised concern on the cardiovascular safety of nonsteroidal antiinflammatory drugs (NSAIDs). We studied safety of NSAID therapy in a nationwide cohort of healthy individuals...
Metformin is associated with improved left ventricular diastolic function measured by tissue Doppler imaging in patients with diabetesCharlotte Andersson
Department of Cardiology, Copenhagen University Hospital, Gentofte, Copenhagen, Denmark
Eur J Endocrinol 163:593-9. 2010..To examine the association between selected glucose-lowering medications and left ventricular (LV) diastolic function in patients with diabetes...
Increased short-term risk of thrombo-embolism or death after interruption of warfarin treatment in patients with atrial fibrillationJakob Raunsø
Department of Cardiology, Copenhagen University Hospital Gentofte, Post 67, Hellerup 2900, Denmark
Eur Heart J 33:1886-92. 2012..The purpose of this study was to assess the risk and timing of thrombo-embolism after warfarin treatment interruption...
Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetesCharlotte Andersson
Department of Cardiology, Gentofte Hospital, Niels Andersens Vej 65, 2900 Hellerup, Denmark
JAMA 308:882-9. 2012..Clinical trials have not convincingly demonstrated that clopidogrel benefits patients with diabetes as much patients without diabetes...
Hospital variation in use of secondary preventive medicine after discharge for first acute myocardial infarction during 1995-2004Søren Rasmussen
National Institute of Public Health, Copenhagen, Denmark
Med Care 46:70-7. 2008..To examine temporal trends in hospital use of secondary preventive medicine after discharge for first acute myocardial infarction (AMI) in Denmark...
Effects of epilepsy and selected antiepileptic drugs on risk of myocardial infarction, stroke, and death in patients with or without previous stroke: a nationwide cohort studyJonas Bjerring Olesen
Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark
Pharmacoepidemiol Drug Saf 20:964-71. 2011..We evaluated the risk of myocardial infarction (MI), stroke, and death associated with epilepsy and examined if this risk was modified by treatment with antiepileptic drugs (AEDs)...
Clarithromycin use and risk of death in patients with ischemic heart diseaseSøren Skøtt Andersen
Department of Cardiology, Gentofte Hospital, Copenhagen, Denmark
Cardiology 116:89-97. 2010..To examine whether treatment with clarithromycin was associated with an increased risk of death in patients with preexisting ischemic heart disease (IHD)...
Duration of clopidogrel treatment and risk of mortality and recurrent myocardial infarction among 11 680 patients with myocardial infarction treated with percutaneous coronary intervention: a cohort studyRikke Sørensen
Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
BMC Cardiovasc Disord 10:6. 2010..We studied the risk of death or recurrent myocardial infarction (MI) in relation to 6- and 12-months clopidogrel treatment among MI patients treated with PCI...
Differences between out-of-hospital cardiac arrest in residential and public locations and implications for public-access defibrillationFredrik Folke
Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark
Circulation 122:623-30. 2010..We examined whether residential OHCA areas suitable for placement of automated external defibrillators could be identified on the basis of demographic characteristics and characterized individuals with OHCA in residential locations...
Cause-specific cardiovascular risk associated with nonsteroidal anti-inflammatory drugs among myocardial infarction patients--a nationwide studyAnne Marie Schjerning Olsen
Department of Cardiology, Copenhagen University Hospital, Hellerup, Denmark
PLoS ONE 8:e54309. 2013..Non steroidal anti-inflammatory drugs (NSAIDs) increase mortality and morbidity after myocardial infarction (MI). We examined cause-specific mortality and morbidity associated with NSAIDs in a nationwide cohort of MI patients...
Use of nonsteroidal anti-inflammatory drugs prior to chronic renal replacement therapy initiation: a nationwide studySøren Lund Kristensen
Department of Cardiology, Copenhagen University Hospital, Gentofte, Hellerup, Denmark
Pharmacoepidemiol Drug Saf 21:428-34. 2012..In this study, we examined NSAID use, aetiology and comorbidity among a national cohort of patients before the initiation of chronic renal replacement therapy (RRT)...
Hospital admissions and pharmacotherapy before out-of-hospital cardiac arrest according to agePeter Weeke
Department of Cardiology, Copenhagen University Hospital, Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
Resuscitation 83:584-90. 2012..We aimed to determine the specific type of healthcare contact shortly before out-of-hospital cardiac arrest (OHCA) across ages...
Diabetes is an independent predictor of survival 17 years after myocardial infarction: follow-up of the TRACE registryThomas Kümler
Department of Cardiology, Rigshopitalet University Hospital, Blegdamsvej, Copenhagen, Denmark
Cardiovasc Diabetol 9:22. 2010..The aim of this study was to systematically evaluate the development of diabetes as an independent long-term prognostic factor after myocardial infarction...
Pharmacotherapy and hospital admissions before out-of-hospital cardiac arrest: a nationwide studyPeter Weeke
Department of Cardiology, Copenhagen University Hospital Gentofte, Denmark
Resuscitation 81:1657-63. 2010..We aimed to determine the extent of contact to the healthcare system before OHCA...
Prognosis after percutaneous coronary intervention in patients with psoriasis: a cohort study using Danish nationwide registriesOle Ahlehoff
Department of Cardiology, Copenhagen University Hospital, Gentofte, Hellerup DK 2900, Denmark
BMC Cardiovasc Disord 12:79. 2012..Psoriasis is an inflammatory disease associated with increased risk of coronary artery disease. However, the potential impact of psoriasis on the prognosis following percutaneous coronary revascularization (PCI) is unknown...
Diabetes is associated with impaired myocardial performance in patients without significant coronary artery diseaseCharlotte Andersson
Department of Cardiology, Gentofte Hospital, University of Copenhagen, Denmark
Cardiovasc Diabetol 9:3. 2010..Echocardiographic tissue Doppler imaging was therefore performed in DM patients without significant CAD to examine whether DM per se influenced cardiac function...
Long-term prognostic importance of diabetes after a myocardial infarction depends on left ventricular systolic functionCharlotte Andersson
Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
Diabetes Care 34:1788-90. 2011..This study was performed to understand how left ventricular function modulates the prognostic importance of diabetes after myocardial infarction (MI)...
Antiepileptic drugs and risk of suicide: a nationwide studyJonas Bjerring Olesen
Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark
Pharmacoepidemiol Drug Saf 19:518-24. 2010..Studies have suggested that AEDs in general increase the risk of suicidal behaviour shortly after initiation. This study investigated possible differences in suicide risk associated with different AEDs...
Cardiovascular safety of non-steroidal anti-inflammatory drugs among healthy individualsEmil Loldrup Fosbøl
Gentofte University Hospital, Department of Cardiology, Hellerup, Denmark
Expert Opin Drug Saf 9:893-903. 2010..Studies have raised concern on the cardiovascular safety of NSAIDs. We studied safety of NSAID therapy in a nationwide cohort of healthy individuals...
[Psoriasis and atherothrombotic disease]Ole Ahlehoff
Kardiologisk Afdeling P, Gentofte Hospital, 2900 Hellerup, Denmark
Ugeskr Laeger 172:1983-6. 2010..and increased risk of atherothrombotic disease. The current review summarises the available evidence in this area of research and calls for increased awareness of cardiovascular risk assessment and treatment in patients with psoriasis...
Moderate overweight is beneficial and severe obesity detrimental for patients with documented atherosclerotic heart diseaseAziza Azimi
Department of Cardiology, Gentofte Hospital, Post 635, Niels Andersens Vej 65, Hellerup 2900, Denmark
Heart 99:655-60. 2013..We explored this paradox further by examining the influence of obesity on survival in patients with verified atherosclerotic heart disease...
Comparative cardiovascular safety of dementia medications: a cross-national studyEmil L Fosbøl
Duke Clinical Research Institute, School of Medicine, Duke University, Durham, North Carolina 27705, USA
J Am Geriatr Soc 60:2283-9. 2012..To compare the cardiovascular safety of currently marketed dementia medications in new users in the United States and Denmark...
Risk of bleeding related to antithrombotic treatment in cardiovascular diseaseRikke Sørensen
Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark
Curr Pharm Des 18:5362-78. 2012....
No association between metal allergy and cardiac in-stent restenosis in patients with dermatitis-results from a linkage studyJacob P Thyssen
Department of Dermato Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, DK 2900 Hellerup, Denmark
Contact Dermatitis 64:138-41. 2011....
