A H Lund

Summary

Affiliation: Biotech Research and Innovation Centre
Country: Denmark

Publications

  1. pmc Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus
    Annette Balle Sørensen
    Department of Molecular Biology, University of Aarhus, Denmark
    Retrovirology 4:46. 2007
  2. ncbi request reprint Epigenetics and cancer
    Anders H Lund
    Division of Molecular Genetics, The Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands
    Genes Dev 18:2315-35. 2004
  3. doi request reprint miR-10 in development and cancer
    A H Lund
    Biotech Research and Innovation Centre and Center for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 Copenhagen, Denmark
    Cell Death Differ 17:209-14. 2010
  4. doi request reprint p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC
    N R Christoffersen
    Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark
    Cell Death Differ 17:236-45. 2010
  5. doi request reprint Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo
    E Leucci
    Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark
    Oncogene 31:5081-9. 2012
  6. doi request reprint miR-339-5p regulates the p53 tumor-suppressor pathway by targeting MDM2
    M D Jansson
    Biotech Research and Innovation Centre and Centre for Epigenetics, University of Copenhagen, Copenhagen, Denmark
    Oncogene 34:1908-18. 2015
  7. ncbi request reprint Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance
    I Muyrers-Chen
    The Netherlands Cancer Institute, Division of Molecular Genetics, 1066 CX Amsterdam, The Netherlands
    Cold Spring Harb Symp Quant Biol 69:319-26. 2004
  8. ncbi request reprint Chromatin-modifying proteins in cancer
    Cathrine K Fog
    Biotech Research and Innovation Centre and Centre for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 Copenhagen Denmark
    APMIS 115:1060-89. 2007
  9. ncbi request reprint Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    Lisa B Frankel
    Biotech Research and Innovation Centre, Bioinformatics Centre, University of Copenhagen, DK 2200 N Copenhagen, Denmark
    J Biol Chem 283:1026-33. 2008
  10. ncbi request reprint Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice
    Anders H Lund
    Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands
    Nat Genet 32:160-5. 2002

Collaborators

  • Maarten Van Lohuizen
  • M Oren
  • E Leucci
  • M D Jansson
  • M Lees
  • N R Christoffersen
  • Lisa B Frankel
  • Annette Balle Sørensen
  • Cathrine K Fog
  • I Muyrers-Chen
  • N D Damas
  • A Jacobsen
  • S Kauppinen
  • L Leoncini
  • S Obad
  • C Bellan
  • K T Jensen
  • A Zriwil
  • L H Gregersen
  • F C Nielsen
  • R Shalgi
  • M Klausen
  • L B Frankel
  • Y Pilpel
  • Morten Lindow
  • Anders Jacobsen
  • Anders Krogh
  • Nanna R Christoffersen
  • Bruce Wang
  • Klaus T Jensen
  • Leticia Quintanilla-Martinez
  • Finn Skou Pedersen
  • Sandra Kunder
  • Matthias Wabl
  • Jörg Schmidt
  • B Tolhuis
  • S W M Bruggeman
  • H Theunissen
  • M E Valk-Lingbeek
  • I Hernández-Muñoz
  • P Taghavi
  • E Verhoeven
  • S Noback
  • D Hulsman
  • P van der Stoop
  • E Tanger
  • E Boutsma

Detail Information

Publications10

  1. pmc Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus
    Annette Balle Sørensen
    Department of Molecular Biology, University of Aarhus, Denmark
    Retrovirology 4:46. 2007
    ..In the present study we investigate the splice pattern as well as the possible effects of mutating the alternative splice sites on the oncogenic properties of the B-lymphomagenic Akv murine leukemia virus...
  2. ncbi request reprint Epigenetics and cancer
    Anders H Lund
    Division of Molecular Genetics, The Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands
    Genes Dev 18:2315-35. 2004
    ..In contrast to genetic cancer causes, the possibility of reversing epigenetic codes may provide new targets for therapeutic intervention...
  3. doi request reprint miR-10 in development and cancer
    A H Lund
    Biotech Research and Innovation Centre and Center for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 Copenhagen, Denmark
    Cell Death Differ 17:209-14. 2010
    ....
  4. doi request reprint p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC
    N R Christoffersen
    Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark
    Cell Death Differ 17:236-45. 2010
    ..Hence, in addition to its integration in the p53 pathway, we show that alternative cancer-related pathways regulate miR-34a, emphasising its significance as a tumour suppressor...
  5. doi request reprint Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo
    E Leucci
    Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark
    Oncogene 31:5081-9. 2012
    ....
  6. doi request reprint miR-339-5p regulates the p53 tumor-suppressor pathway by targeting MDM2
    M D Jansson
    Biotech Research and Innovation Centre and Centre for Epigenetics, University of Copenhagen, Copenhagen, Denmark
    Oncogene 34:1908-18. 2015
    ..Furthermore, we show that a negative correlation between miR-339-5p and MDM2 expression exists in human cancer, implying that the interaction is important for cancer development...
  7. ncbi request reprint Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance
    I Muyrers-Chen
    The Netherlands Cancer Institute, Division of Molecular Genetics, 1066 CX Amsterdam, The Netherlands
    Cold Spring Harb Symp Quant Biol 69:319-26. 2004
  8. ncbi request reprint Chromatin-modifying proteins in cancer
    Cathrine K Fog
    Biotech Research and Innovation Centre and Centre for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 Copenhagen Denmark
    APMIS 115:1060-89. 2007
    ..Here we discuss how epigenetic alterations influence cancer development and review known cancer-associated alterations in chromatin-modifying proteins...
  9. ncbi request reprint Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    Lisa B Frankel
    Biotech Research and Innovation Centre, Bioinformatics Centre, University of Copenhagen, DK 2200 N Copenhagen, Denmark
    J Biol Chem 283:1026-33. 2008
    ..We furthermore found that the tumor suppressor protein Programmed Cell Death 4 (PDCD4) is regulated by miR-21 and demonstrated that PDCD4 is a functionally important target for miR-21 in breast cancer cells...
  10. ncbi request reprint Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice
    Anders H Lund
    Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands
    Nat Genet 32:160-5. 2002
    ....