Research Topics
Species | A H LundSummaryAffiliation: Biotech Research and Innovation Centre Country: Denmark Publications
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Detail Information
Publications
Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virusAnnette Balle Sørensen
Department of Molecular Biology, University of Aarhus, Denmark
Retrovirology 4:46. 2007..In the present study we investigate the splice pattern as well as the possible effects of mutating the alternative splice sites on the oncogenic properties of the B-lymphomagenic Akv murine leukemia virus...
Epigenetics and cancerAnders H Lund
Division of Molecular Genetics, The Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands
Genes Dev 18:2315-35. 2004..In contrast to genetic cancer causes, the possibility of reversing epigenetic codes may provide new targets for therapeutic intervention...
miR-10 in development and cancerA H Lund
Biotech Research and Innovation Centre and Center for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 Copenhagen, Denmark
Cell Death Differ 17:209-14. 2010....
p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYCN R Christoffersen
Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark
Cell Death Differ 17:236-45. 2010..Hence, in addition to its integration in the p53 pathway, we show that alternative cancer-related pathways regulate miR-34a, emphasising its significance as a tumour suppressor...
Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivoE Leucci
Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark
Oncogene 31:5081-9. 2012....
Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenanceI Muyrers-Chen
The Netherlands Cancer Institute, Division of Molecular Genetics, 1066 CX Amsterdam, The Netherlands
Cold Spring Harb Symp Quant Biol 69:319-26. 2004
Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient miceAnders H Lund
Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands
Nat Genet 32:160-5. 2002....
Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cellsLisa B Frankel
Biotech Research and Innovation Centre, Bioinformatics Centre, University of Copenhagen, DK 2200 N Copenhagen, Denmark
J Biol Chem 283:1026-33. 2008..We furthermore found that the tumor suppressor protein Programmed Cell Death 4 (PDCD4) is regulated by miR-21 and demonstrated that PDCD4 is a functionally important target for miR-21 in breast cancer cells...
Chromatin-modifying proteins in cancerCathrine K Fog
Biotech Research and Innovation Centre and Centre for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 Copenhagen Denmark
APMIS 115:1060-89. 2007..Here we discuss how epigenetic alterations influence cancer development and review known cancer-associated alterations in chromatin-modifying proteins...
