Klaus H Hansen

Summary

Affiliation: Biotech Research and Innovation Centre
Country: Denmark

Publications

  1. doi request reprint A model for transmission of the H3K27me3 epigenetic mark
    Klaus H Hansen
    Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark
    Nat Cell Biol 10:1291-300. 2008
  2. pmc Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2
    Diego Pasini
    Biotech Research and Innovation Centre BRIC and Centre for Epigenetics, University of Copenhagen, 2200 Copenhagen, Denmark
    Genes Dev 22:1345-55. 2008
  3. pmc The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
    Adrian P Bracken
    Centre for Epigenetics, Biotech Research and Innovation Centre BRIC, University of Copenhagen, Copenhagen 2200, Denmark
    Genes Dev 21:525-30. 2007
  4. ncbi request reprint RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3
    Jesper Christensen
    Centre for Epigenetics, University of Copenhagen, Copenhagen, Denmark
    Cell 128:1063-76. 2007
  5. pmc Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus
    Nikolaj Dietrich
    Centre for Epigenetics and Biotech Research and Innovation Centre BRIC, University of Copenhagen, Copenhagen, Denmark
    EMBO J 26:1637-48. 2007
  6. ncbi request reprint Epigenetic inheritance through self-recruitment of the polycomb repressive complex 2
    Klaus H Hansen
    Biotech Research and Innovation Centre BRIC, University of Copenhagen, Copenhagen, Denmark
    Epigenetics 4:133-8. 2009
  7. ncbi request reprint The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
    Paul A C Cloos
    Biotech Research and Innovation Centre, Fruebjergvej 3, 2100 Copenhagen, Denmark
    Nature 442:307-11. 2006

Detail Information

Publications7

  1. doi request reprint A model for transmission of the H3K27me3 epigenetic mark
    Klaus H Hansen
    Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark
    Nat Cell Biol 10:1291-300. 2008
    ....
  2. pmc Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2
    Diego Pasini
    Biotech Research and Innovation Centre BRIC and Centre for Epigenetics, University of Copenhagen, 2200 Copenhagen, Denmark
    Genes Dev 22:1345-55. 2008
    ..Taken together, these results demonstrate an elegant mechanism for repression of developmental genes by the coordinated regulation of epigenetic marks involved in repression and activation of transcription...
  3. pmc The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
    Adrian P Bracken
    Centre for Epigenetics, Biotech Research and Innovation Centre BRIC, University of Copenhagen, Copenhagen 2200, Denmark
    Genes Dev 21:525-30. 2007
    ..These results provide a model for how the INK4A-ARF locus is activated and how Polycombs contribute to cancer...
  4. ncbi request reprint RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3
    Jesper Christensen
    Centre for Epigenetics, University of Copenhagen, Copenhagen, Denmark
    Cell 128:1063-76. 2007
    ..Taken together, these results suggest that H3K4me3/me2 demethylation regulated by the JARID1 family plays an important role during development...
  5. pmc Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus
    Nikolaj Dietrich
    Centre for Epigenetics and Biotech Research and Innovation Centre BRIC, University of Copenhagen, Copenhagen, Denmark
    EMBO J 26:1637-48. 2007
    ..On the basis of these results, we conclude that CBX8 is an essential component of one of the PRC1 complexes, which directly regulate the expression of numerous target genes, including the INK4A-ARF locus, involved in cell-fate decisions...
  6. ncbi request reprint Epigenetic inheritance through self-recruitment of the polycomb repressive complex 2
    Klaus H Hansen
    Biotech Research and Innovation Centre BRIC, University of Copenhagen, Copenhagen, Denmark
    Epigenetics 4:133-8. 2009
    ..Here we discuss the implications of our results in further detail...
  7. ncbi request reprint The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
    Paul A C Cloos
    Biotech Research and Innovation Centre, Fruebjergvej 3, 2100 Copenhagen, Denmark
    Nature 442:307-11. 2006
    ..Thus, in addition to identifying GASC1 as a histone trimethyl demethylase, we suggest a model for how this enzyme might be involved in cancer development, and propose it as a target for anti-cancer therapy...