Betina Kerstin Lundholt

Summary

Affiliation: BioImage A/S
Country: Denmark

Publications

  1. ncbi A simple technique for reducing edge effect in cell-based assays
    Betina Kerstin Lundholt
    BioImage A S, Moerkhoej Bygade 28, DK 2860 Soeborg, Denmark
    J Biomol Screen 8:566-70. 2003
  2. ncbi Identification of RAS-mitogen-activated protein kinase signaling pathway modulators in an ERF1 redistribution screen
    Charlotta Granas
    BioImage A S, Copenhagen, Denmark
    J Biomol Screen 11:423-34. 2006
  3. ncbi A simple cell-based HTS assay system to screen for inhibitors of p53-Hdm2 protein-protein interactions
    Betina Kerstin Lundholt
    Fisher BioImage ApS, Søborg, Denmark
    Assay Drug Dev Technol 4:679-88. 2006
  4. ncbi High content screening for G protein-coupled receptors using cell-based protein translocation assays
    Charlotta Granas
    BioImage A S, Copenhagen, Denmark
    Comb Chem High Throughput Screen 8:301-9. 2005
  5. ncbi Identification of Akt pathway inhibitors using redistribution screening on the FLIPR and the IN Cell 3000 analyzer
    Betina Kerstin Lundholt
    BioImage A/S, Copenhagen, Denmark
    J Biomol Screen 10:20-9. 2005

Collaborators

  • Len Pagliaro
  • Morten Praestegaard
  • Robert Terry
  • Charlotta Granas
  • Hans-Christian Pedersen
  • Viggo Linde
  • Hans Christian Pedersen
  • Eva Maria Damsgaard Nielsen
  • Sara Petersen Bjørn
  • Christian Krogh-Jensen
  • Frosty Loechel
  • Søren Jensby Nielsen
  • Eva-Maria Damsgaard Nielsen
  • Mette M Rosenkilde
  • Christian Krog-Jensen
  • Arne Heydorn

Detail Information

Publications5

  1. ncbi A simple technique for reducing edge effect in cell-based assays
    Betina Kerstin Lundholt
    BioImage A S, Moerkhoej Bygade 28, DK 2860 Soeborg, Denmark
    J Biomol Screen 8:566-70. 2003
    ..Here, the authors show that the simple, inexpensive approach of incubating newly seeded plates at room temperature before placing them in a 37 degrees C CO(2) incubator yields a significant reduction in edge effect...
  2. ncbi Identification of RAS-mitogen-activated protein kinase signaling pathway modulators in an ERF1 redistribution screen
    Charlotta Granas
    BioImage A S, Copenhagen, Denmark
    J Biomol Screen 11:423-34. 2006
    ..The results also show that cell-based, high-content Redistribution screens can detect compounds with different modes of action and reveal novel targets in a pathway known to be disease relevant...
  3. ncbi A simple cell-based HTS assay system to screen for inhibitors of p53-Hdm2 protein-protein interactions
    Betina Kerstin Lundholt
    Fisher BioImage ApS, Søborg, Denmark
    Assay Drug Dev Technol 4:679-88. 2006
    ..Here we show that by taking advantage of the translocation behavior of nonbound p53, it is possible to identify true inhibitors of the p53-Hdm2 interaction by extracting high content information from the acquired images...
  4. ncbi High content screening for G protein-coupled receptors using cell-based protein translocation assays
    Charlotta Granas
    BioImage A S, Copenhagen, Denmark
    Comb Chem High Throughput Screen 8:301-9. 2005
    ....
  5. ncbi Identification of Akt pathway inhibitors using redistribution screening on the FLIPR and the IN Cell 3000 analyzer
    Betina Kerstin Lundholt
    BioImage A/S, Copenhagen, Denmark
    J Biomol Screen 10:20-9. 2005
    ..Protein translocation assays emerge as powerful tools for hit identification and characterization...