Peter Vestergaard

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. ncbi request reprint Vitamin D status, seasonal variations, parathyroid adenoma weight and bone mineral density in primary hyperparathyroidism
    B Moosgaard
    Aarhus Bone and Mineral Research Group Department of Endocrinology and Metabolism C, Aarhus University Hospital, Denmark
    Clin Endocrinol (Oxf) 63:506-13. 2005
  2. ncbi request reprint Anxiolytics, sedatives, antidepressants, neuroleptics and the risk of fracture
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus, Tage Hansens Gade 2, 8000, Aarhus C, Denmark
    Osteoporos Int 17:807-16. 2006
  3. ncbi request reprint Pain-relief medication and risk of fractures
    Peter Vestergaard
    Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Curr Drug Saf 3:199-203. 2008
  4. ncbi request reprint [Treatment and prevention of osteoporosis in patients with decreased renal function]
    Peter Vestergaard
    Aalborg Sygehus, Endokrinologisk Afdeling, Aalborg
    Ugeskr Laeger 170:227-30. 2008
  5. ncbi request reprint Socioeconomic aspects of fractures within universal public healthcare: a nationwide case-control study from Denmark
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus, Denmark
    Scand J Public Health 34:371-7. 2006
  6. ncbi request reprint Fracture risk associated with use of nonsteroidal anti-inflammatory drugs, acetylsalicylic acid, and acetaminophen and the effects of rheumatoid arthritis and osteoarthritis
    P Vestergaard
    Department of Endocrinology and Metabolism, Aarhus Sygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000, Aarhus C, Denmark
    Calcif Tissue Int 79:84-94. 2006
  7. pmc Fractures in users of antidepressants and anxiolytics and sedatives: effects of age and dose
    P Vestergaard
    Department of Endocrinology and Internal Medicine MEA, Aarhus University Hospital THG, Tage Hansens Gade 2, 8000, Aarhus C, Denmark
    Osteoporos Int 24:671-80. 2013
  8. doi request reprint Selective serotonin reuptake inhibitors and other antidepressants and risk of fracture
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000 Aarhus C, Denmark
    Calcif Tissue Int 82:92-101. 2008
  9. doi request reprint Risk of femoral shaft and subtrochanteric fractures among users of bisphosphonates and raloxifene
    P Vestergaard
    Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
    Osteoporos Int 22:993-1001. 2011
  10. ncbi request reprint Codon Y791F mutations in a large kindred: is prophylactic thyroidectomy always indicated?
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Sygehus, Aarhus University Hospital, Aarhus, Tage Hansens Gade 2, 8000, Aarhus C, Denmark
    World J Surg 31:996-1001; discussion 1002-4. 2007

Detail Information

Publications140 found, 100 shown here

  1. ncbi request reprint Vitamin D status, seasonal variations, parathyroid adenoma weight and bone mineral density in primary hyperparathyroidism
    B Moosgaard
    Aarhus Bone and Mineral Research Group Department of Endocrinology and Metabolism C, Aarhus University Hospital, Denmark
    Clin Endocrinol (Oxf) 63:506-13. 2005
    ..Primary hyperparathyroidism (PHPT) and vitamin D insufficiency are common conditions that can occur in combination. However, low plasma 25-hydroxyvitamin D (25OHD) may also enhance the risk of PHPT or modify disease severity...
  2. ncbi request reprint Anxiolytics, sedatives, antidepressants, neuroleptics and the risk of fracture
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus, Tage Hansens Gade 2, 8000, Aarhus C, Denmark
    Osteoporos Int 17:807-16. 2006
    ..Our objective was to study the association between fracture risk and the use of anxiolytics and sedatives (benzodiazepines, etc.), neuroleptics and antidepressants...
  3. ncbi request reprint Pain-relief medication and risk of fractures
    Peter Vestergaard
    Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Curr Drug Saf 3:199-203. 2008
    ..More research is needed to determine if some analgesics are safer than others with respect to fracture risk...
  4. ncbi request reprint [Treatment and prevention of osteoporosis in patients with decreased renal function]
    Peter Vestergaard
    Aalborg Sygehus, Endokrinologisk Afdeling, Aalborg
    Ugeskr Laeger 170:227-30. 2008
    ..Most drugs seem safe in terms of affecting renal function. The aim should be to control calcium and vitamin D metabolism in patients with severely decreased renal function (GFR<30 ml/min) or on dialysis...
  5. ncbi request reprint Socioeconomic aspects of fractures within universal public healthcare: a nationwide case-control study from Denmark
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus, Denmark
    Scand J Public Health 34:371-7. 2006
    ..To investigate the effects of income and other socioeconomic variables on fracture risk adjusted for disease-related confounders as fractures are a major public health problem...
  6. ncbi request reprint Fracture risk associated with use of nonsteroidal anti-inflammatory drugs, acetylsalicylic acid, and acetaminophen and the effects of rheumatoid arthritis and osteoarthritis
    P Vestergaard
    Department of Endocrinology and Metabolism, Aarhus Sygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000, Aarhus C, Denmark
    Calcif Tissue Int 79:84-94. 2006
    ..86, 95% CI 1.68-2.07). Weak analgesics may be associated with fracture risk in a varying way. The effects in most cases were small. Falls may be one reason for the increase in fracture risk with some NSAIDs...
  7. pmc Fractures in users of antidepressants and anxiolytics and sedatives: effects of age and dose
    P Vestergaard
    Department of Endocrinology and Internal Medicine MEA, Aarhus University Hospital THG, Tage Hansens Gade 2, 8000, Aarhus C, Denmark
    Osteoporos Int 24:671-80. 2013
    ..Depression per se did not seem associated with fractures...
  8. doi request reprint Selective serotonin reuptake inhibitors and other antidepressants and risk of fracture
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000 Aarhus C, Denmark
    Calcif Tissue Int 82:92-101. 2008
    ..While selective serotonin receptor uptake inhibitors were associated with an increased fracture risk, tricyclic antidepressants and the group of other antidepressants were not systematically associated with fracture risk...
  9. doi request reprint Risk of femoral shaft and subtrochanteric fractures among users of bisphosphonates and raloxifene
    P Vestergaard
    Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
    Osteoporos Int 22:993-1001. 2011
    ..This may suggest an effect of the underlying disease rather than the drugs used...
  10. ncbi request reprint Codon Y791F mutations in a large kindred: is prophylactic thyroidectomy always indicated?
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Sygehus, Aarhus University Hospital, Aarhus, Tage Hansens Gade 2, 8000, Aarhus C, Denmark
    World J Surg 31:996-1001; discussion 1002-4. 2007
    ..We present a large kindred with the Y791F mutation in the RET proto-oncogene that did not have medullary thyroid carcinomas...
  11. pmc Cohort study on effects of parathyroid surgery on multiple outcomes in primary hyperparathyroidism
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    BMJ 327:530-4. 2003
    ..To assess the effects of surgery compared with conservative treatment (no surgery) for primary hyperparathyroidism...
  12. ncbi request reprint Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes--a meta-analysis
    P Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, 8000, Aarhus C, Denmark
    Osteoporos Int 18:427-44. 2007
    ..Diabetes affects bone metabolism. The hypothesis was that type 1 (T1D) and type 2 (T2D) affects BMD and fracture risk differently...
  13. ncbi request reprint [No effect of calcium supplementation on bone mineral density in children. Survey of a Cochrane review]
    Peter Vestergaard
    Arhus Universitetshospital, Arhus Sygehus, Medicinsk Endokrinologisk Afdeling C, Arhus C
    Ugeskr Laeger 169:2512-5. 2007
  14. ncbi request reprint [Teriparatide (human recombinant 1-34 parathyroid hormone)--a new treatment regimen for severe osteoporosis]
    Peter Vestergaard
    Arhus Universitetshospital, Arhus Sygehus, Medicinsk Endokrinologisk Afdeling C
    Ugeskr Laeger 166:2653-5. 2004
  15. ncbi request reprint [Can measurement of basal calcitonin replace the pentagastrin test?]
    Peter Vestergaard
    Osteoporoseklinikken, Arhus Sygehus, DK 8000 Arhus C
    Ugeskr Laeger 170:3238-42. 2008
    ..Traditionally, stimulation of calcitonin secretion with pentagastrin has been used. This may, however, cause significant discomfort for the patient. We studied whether measurements of basal calcitonin could replace the pentagastrin test...
  16. ncbi request reprint Effects of treatment with fluoride on bone mineral density and fracture risk--a meta-analysis
    P Vestergaard
    The Osteoporosis Clinic, Department of Endocrinology and Metabolism C, Aarhus University Hospital Aarhus Amtssygehus, Tage Hansens Gade 2, 8000 Aarhus C, Denmark
    Osteoporos Int 19:257-68. 2008
    ..3, 95% CI: 0.1-0.9 for vertebral and OR = 0.5, 95% CI: 0.3-0.8 for non-vertebral fractures...
  17. ncbi request reprint [Incidence of primary hyperparathyroidism, frequency of surgical interventions and mortality based on the data from the National Patient Registry]
    Peter Vestergaard
    Arhus Universitetshospital, Arhus Amtssygehus, Medicinsk Endokrinologisk Afdeling C
    Ugeskr Laeger 166:41-5. 2004
  18. ncbi request reprint Reduced bone mineral density and increased bone turnover in Prader-Willi syndrome compared with controls matched for sex and body mass index--a cross-sectional study
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital and Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
    J Pediatr 144:614-9. 2004
    ..To study bone mineral status, body composition, and biochemical markers of bone turnover in Prader-Willi syndrome (PWS)...
  19. ncbi request reprint Fracture risk associated with parkinsonism and anti-Parkinson drugs
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000, Aarhus C, Denmark
    Calcif Tissue Int 81:153-61. 2007
    ..Use of neuroleptics and, to some degree, levodopa was associated with increased risk of fractures...
  20. ncbi request reprint Changes in bone turnover, bone mineral and fracture risk induced by drugs used to treat epilepsy
    Peter Vestergaard
    Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Curr Drug Saf 3:168-72. 2008
    ..From a fracture point of view most AEDs seem to be relatively safe...
  21. ncbi request reprint Effect of tamoxifen and aromatase inhibitors on the risk of fractures in women with breast cancer
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Tage Hansens Gade 2, Aarhus C, Denmark
    Calcif Tissue Int 82:334-40. 2008
    ..Aromatase inhibitors were associated with a significant increase in the risk of fractures. In women at high risk of fractures, supplementary measures, i.e., bisphosphonates, may be considered...
  22. doi request reprint Use of bisphosphonates and risk of breast cancer
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, The Osteoporosis Clinic, Aarhus University Hospital, Tage Hansens Gade 2, 8000 Aarhus C, Denmark
    Calcif Tissue Int 88:255-62. 2011
    ..Bisphosphonate treatment in women was associated with a reduced risk of breast cancer. However, no causal relationship seemed to be present...
  23. ncbi request reprint Fracture risk in patients with celiac Disease, Crohn's disease, and ulcerative colitis: a nationwide follow-up study of 16,416 patients in Denmark
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    Am J Epidemiol 156:1-10. 2002
    ..The severity of the inflammatory process and the amount of corticosteroids given may explain the difference in fracture risk...
  24. ncbi request reprint Smoking and thyroid disorders--a meta-analysis
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 146:153-61. 2002
    ..Smoking has been associated with Graves' disease, but it remains unclear if the association is present in other thyroid disorders...
  25. ncbi request reprint Medical treatment of primary, secondary, and tertiary hyperparathyroidism
    Peter Vestergaard
    Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
    Curr Drug Saf 6:108-13. 2011
    ..It may also be used in tertiary hyperparathyroidism. Newer analogues of vitamin D such as paricalcitol have also been introduced, which may have an advantage over traditional compounds such as alphacalcidol and calcitriol...
  26. doi request reprint Risk of newly diagnosed type 2 diabetes is reduced in users of alendronate
    Peter Vestergaard
    Department of Endocrinology and Internal Medicine, The Osteoporosis Clinic, Aarhus University Hospital THG, Denmark
    Calcif Tissue Int 89:265-70. 2011
    ..Antiresorptive drugs do not seem associated with an increased risk of diabetes, but they may perhaps provide a protective effect related to the suppression of bone turnover. However, further studies are needed...
  27. ncbi request reprint Anti-resorptive therapy for the prevention of postmenopausal osteoporosis : when should treatment begin?
    Peter Vestergaard
    The Osteoporosis Clinic Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    Treat Endocrinol 4:263-77. 2005
    ..In some scenarios, treatment with bisphosphonates may be cost effective in a 50-year-old woman with an absolute hip fracture risk of >or=1.1% over the next 10 years...
  28. ncbi request reprint [Treatment of mineral bone disorder with pharmaceuticals which influence the calcium phosphor turnover]
    Peter Vestergaard
    Endokrinologisk Afdeling, Medicinerhuset, Aalborg Sygehus Syd, Mølleparkvej 4, Aalborg
    Ugeskr Laeger 174:2931-4. 2012
    ..We focus on the management of these conditions by administration of calcium, vitamin D (ergocalciferol and cholecalciferol), vitamin D receptor activators (calcitriol, alphacalcidiol), phosphate binders and calcimimetics (cinacalcet)...
  29. ncbi request reprint Gastric and esophagus events before and during treatment of osteoporosis
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus C, Denmark
    Calcif Tissue Int 86:110-5. 2010
    ..This points at an effect of the underlying condition being treated or comorbid conditions and drugs being provided in patients with osteoporosis, such as nonsteroidal anti-inflammatory drugs and corticosteroids...
  30. doi request reprint Risk of fractures associated with treatment for benign prostate hyperplasia in men
    P Vestergaard
    Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
    Osteoporos Int 22:731-7. 2011
    ..In our study, neither 5-α-reductase inhibitors nor α-blockers were associated with negative effects on fractures, α-blockers perhaps being associated with a limited decrease in fractures...
  31. pmc Vitamin D status and bone and connective tissue turnover in brown bears (Ursus arctos) during hibernation and the active state
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus University Hospital, Aarhus, Denmark tele dk
    PLoS ONE 6:e21483. 2011
    ..In contrast, brown bears (Ursus arctos) are highly immobilised for half of the year during hibernation without signs of bone loss and therefore may serve as a model for prevention of osteoporosis...
  32. pmc Loss of life years after a hip fracture
    Peter Vestergaard
    Department of Endocrinology and Metabolism, Aarhus University Hospital, Aarhus, Denmark
    Acta Orthop 80:525-30. 2009
    ..Patients with a hip fracture have a high mortality; however, it is not clear how large the loss of life-years is over an extended observation period...
  33. pmc Treating postmenopausal osteoporosis in women at increased risk of fracture - critical appraisal of bazedoxifene: a review
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus, Denmark
    Int J Womens Health 1:97-103. 2010
    ..40 to 1.20). In general post-hoc defined subgroup analyses should be interpreted with caution. However, the results indicate that bazedoxifene may be effective in preventing vertebral fractures in postmenopausal women with osteoporosis...
  34. ncbi request reprint Diabetes, cancer and treatment - a mini-review
    Peter Vestergaard
    Clinical Institute, Aalborg University, Room C2 201, Fredrik Bajers Vej 7C, DK 9220 Aalborg, Denmark
    Curr Drug Saf 8:292-5. 2013
    ..To conduct a systematic review of the published pre-clinical in vitro and in vivo evidence for plausible mechanisms underlying the risk of cancer associated with insulin and insulin analogues...
  35. doi request reprint Bone diseases. Incident fractures during treatment for osteoporosis
    Peter Vestergaard
    Department of Clinical Medicine, Aalborg University and Department of Endocrinology, Aalborg University Hospital, Mølleparkvej 4, Aalborg, Denmark
    Nat Rev Rheumatol 9:508-10. 2013
    ..Predictors of the new definition have now been reported and include ≥2 falls within the past year. Preventing fractures in the most at-risk patients, however, requires improved management strategies...
  36. ncbi request reprint Increasing incidence of primary hyperparathyroidism in Denmark
    Ali Abood
    Institute for Medicine and Health Technology, Aalborg University, Aalborg, Denmark
    Dan Med J 60:A4567. 2013
    ..In the present study, we evaluated trends in the incidence of primary hyperparathyroidism in Denmark up to 2010...
  37. doi request reprint Effects of paracetamol, non-steroidal anti-inflammatory drugs, acetylsalicylic acid, and opioids on bone mineral density and risk of fracture: results of the Danish Osteoporosis Prevention Study (DOPS)
    P Vestergaard
    Department of Endocrinology and Internal Medicine MEA, Aarhus University Hospital, Aarhus, Denmark
    Osteoporos Int 23:1255-65. 2012
    ..None of the pain medications influenced bone mineral density or loss. NSAID were associated with an increased fracture risk...
  38. ncbi request reprint Oral contraceptive use and risk of fractures
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Amtssygehus, DK 8000 Aarhus, Denmark
    Contraception 73:571-6. 2006
    ..Prior studies have suggested that oral contraceptives (OCs) may be associated with an increased fracture risk. However, the previous studies have only performed a limited adjustment for other potential risk factors...
  39. doi request reprint Anxiolytics and sedatives and risk of fractures: effects of half-life
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus University, Aarhus, Denmark
    Calcif Tissue Int 82:34-43. 2008
    ..However, the increased risk of fractures with past use may suggest an effect of the condition for which the drug was prescribed rather than the drug per se (confounding by indication)...
  40. ncbi request reprint Proton pump inhibitors, histamine H2 receptor antagonists, and other antacid medications and the risk of fracture
    P Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000, Aarhus C, Denmark
    Calcif Tissue Int 79:76-83. 2006
    ..In all cases, the changes in risk estimates were small and the clinical significance was limited...
  41. ncbi request reprint Methotrexate, azathioprine, cyclosporine, and risk of fracture
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000, Aarhus C, Denmark
    Calcif Tissue Int 79:69-75. 2006
    ..It thus seems that the underlying disease for which the treatment is administered may be responsible for much of the increase in fracture risk rather than the drugs used to treat the disorder in question...
  42. ncbi request reprint Fracture risk in patients with chronic lung diseases treated with bronchodilator drugs and inhaled and oral corticosteroids
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000 Aarhus C, Denmark
    Chest 132:1599-607. 2007
    ..Chronic lung diseases and drugs used to treat patients with chronic lung diseases may be associated with an increased fracture risk...
  43. ncbi request reprint Effects of parathyroid hormone alone or in combination with antiresorptive therapy on bone mineral density and fracture risk--a meta-analysis
    P Vestergaard
    The Osteoporosis Clinic, Department of Endocrinology, Aarhus University Hospital, Aarhus C, Denmark
    Osteoporos Int 18:45-57. 2007
    ..The effects of parathyroid hormone (PTH) alone or in combination with antiresorptive therapy on changes in bone mineral density (BMD) and fracture risk were studied...
  44. ncbi request reprint Fracture risk associated with the use of morphine and opiates
    P Vestergaard
    Department of Endocrinology and Metabolism, Aarhus Sygehus, Aarhus University Hospital, Aarhus, Denmark
    J Intern Med 260:76-87. 2006
    ..To study the effect of morphine and opiates on fracture risk...
  45. ncbi request reprint Severity of vertebral fracture reflects deterioration of bone microarchitecture
    H K Genant
    Department of Radiology, University of California, 533 Parnassus Avenue, Suite U368E, San Francisco, CA 94143 1250, USA
    Osteoporos Int 18:69-76. 2007
    ..The objective of this study was to determine whether assessment of four grades of vertebral fracture severity could serve as a noninvasive surrogate marker for trabecular bone volume and microarchitecture...
  46. ncbi request reprint Fracture reducing potential of hormone replacement therapy on a population level
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Sygehus, Aarhus University Hospital, The Osteoporosis Clinic, Aarhus Amtssygehus, Tage Hansens Gade 2, DK 8000 Aarhus C, Denmark
    Maturitas 54:285-93. 2006
    ....
  47. ncbi request reprint [Strongly increasing incidence of hip fractures in Denmark from 1977 to 1999]
    Peter Vestergaard
    Aalborg Sygehus, Endokrinologisk Afdeling
    Ugeskr Laeger 170:621-3. 2008
    ..The incidence of hip fractures has been increasing throughout the world including the Nordic countries. The aim of this study was to examine if there is a similar trend in Denmark...
  48. doi request reprint Osteoarthritis and risk of fractures
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    Calcif Tissue Int 84:249-56. 2009
    ..OA seems to be associated with a decreased risk of fractures at multiple skeletal sites as well as sites far from the location of OA. This may indicate systemic effects on bone strength, especially in areas rich in cortical bone...
  49. ncbi request reprint [Management of serum calcium with cinacelet in parathyroid cancer]
    Peter Vestergaard
    Medicinsk afdeling C, Arhus Universitetshospital, Arhus Sygehus, DK 8000 Arhus C
    Ugeskr Laeger 171:3004-6. 2009
    ..In the other case, cinacalcet controlled serum calcium during a prolonged time period despite metastases. However, increasing doses of cinacalcet combined with more frequent intravenous bisphosphonate were necessary...
  50. ncbi request reprint Use of bisphosphonates and raloxifene and risk of deep venous thromboembolism and pulmonary embolism
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Tage Hansens Gade 2, 8000 Arhus C, Denmark
    Osteoporos Int 21:1591-7. 2010
    ..In a cohort study, we observed an increased risk also with the bisphosphonates. However, the increase was present already before the start of bisphosphonates pointing at an effect of the underlying condition...
  51. doi request reprint Risk of atrial fibrillation associated with use of bisphosphonates and other drugs against osteoporosis: a cohort study
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Tage Hansens Gade 2, 8000 Arhus C, Denmark
    Calcif Tissue Int 86:335-42. 2010
    ..In conclusion, oral bisphosphonates do not seem to be associated with an excess risk of atrial fibrillation. Any excess risk seen in prior studies may be due to confounding from COPD...
  52. doi request reprint Stroke in relation to use of raloxifene and other drugs against osteoporosis
    P Vestergaard
    Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000 Arhus C, Denmark
    Osteoporos Int 22:1037-45. 2011
    ..In a cohort study, we found no excess risk of stroke with raloxifene; whereas, an excess risk of stroke and fatal stroke was seen with alendronate and etidronate. However, the excess risks were small...
  53. ncbi request reprint High-dose treatment with vitamin A analogues and risk of fractures
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Tage Hansens Gade 2, DK 8000 Aarhus C, Denmark
    Arch Dermatol 146:478-82. 2010
    ..To study fracture risk associated with use of systemic vitamin A analogue (isotretinoin and acitretin) treatment...
  54. ncbi request reprint Skeletal effects of drugs to treat cancer
    Peter Vestergaard
    Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Curr Drug Saf 3:173-7. 2008
    ..With the increasing long-term survival of patients with cancer, preventive measures against osteoporosis must be considered...
  55. doi request reprint Are antiresorptive drugs effective against fractures in patients with diabetes?
    Peter Vestergaard
    The Osteoporosis Clinic, Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Denmark
    Calcif Tissue Int 88:209-14. 2011
    ..Therefore, patients with diabetes should receive treatment for osteoporosis in the same way as nondiabetic patients...
  56. doi request reprint Fracture risks of antidepressants
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Tage Hansens Gade 2, DK 8000 Aarhus C, Denmark
    Expert Rev Neurother 9:137-41. 2009
    ..In the interpretation, the effect of confounding by indication should be remembered; patients with depression may have an increased risk of fractures per se...
  57. doi request reprint Diabetes and its complications and their relationship with risk of fractures in type 1 and 2 diabetes
    Peter Vestergaard
    The Osteoporosis Clinic, Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, 8000 Aarhus C, Denmark
    Calcif Tissue Int 84:45-55. 2009
    ....
  58. ncbi request reprint Fracture risk associated with different types of oral corticosteroids and effect of termination of corticosteroids on the risk of fractures
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus Sygehus, Tage Hansens Gade 2, 8000, Aarhus C, Denmark
    Calcif Tissue Int 82:249-57. 2008
    ..Hydrocortisone was not associated with an increase in the risk of fractures. It may take a year from last use of prednisolone/prednisone before fracture risk returns to that of the general population...
  59. ncbi request reprint [Osteoporosis and fractures associated with drugs]
    Peter Vestergaard
    Arhus Sygehus, Osteoporoseklinikken, Arhus C
    Ugeskr Laeger 170:1550-5. 2008
    ..Pain medication varied from no effect to an increased fracture risk...
  60. ncbi request reprint [Medical treatment of patients with primary hyperparathyroidism]
    Peter Vestergaard
    Osteoporoseklinikken, Arhus Universitetshospital, Arhus Sygehus THG, DK 8000 Arhus C
    Ugeskr Laeger 171:2284-7. 2009
    ..However, PHPT can cause other complications that need special attention regarding prevention and treatment during follow-up...
  61. doi request reprint Fracture risk in patients with different types of cancer
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    Acta Oncol 48:105-15. 2009
    ..Few studies on the risk of fractures in patients with cancer exist, and little is known on the mechanisms of fractures in patients with cancer. We studied the risk of fracture in patients with various types of cancer...
  62. ncbi request reprint Skeletal effects of systemic and topical corticosteroids
    Peter Vestergaard
    Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, Denmark
    Curr Drug Saf 3:190-3. 2008
    ....
  63. ncbi request reprint Fracture risk in very young women using combined oral contraceptives
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, DK 8000 Aarhus, Denmark
    Contraception 78:358-64. 2008
    ..Little is known on fracture risk in young women using oral contraceptives...
  64. doi request reprint The effects of depot medroxyprogesterone acetate and intrauterine device use on fracture risk in Danish women
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, DK 8000 Aarhus, Denmark
    Contraception 78:459-64. 2008
    ..Depot medroxyprogesterone acetate (DMPA) use may be associated with an increased risk of fractures; however, nothing is known about the risk associated with intrauterine contraceptive device (IUD) use...
  65. doi request reprint Hypertension is a risk factor for fractures
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, 8000 Aarhus C, Denmark
    Calcif Tissue Int 84:103-11. 2009
    ..The fracture risk in hypertension may explain why antihypertensive drugs as a class effect are associated with a decreased risk of fractures. These drugs may counter some of the deleterious effects of high blood pressure...
  66. doi request reprint Acute myocardial infarction and atherosclerosis of the coronary arteries in patients treated with drugs against osteoporosis: calcium in the vessels and not the bones?
    Peter Vestergaard
    The Osteoporosis Clinic, Department of Endocrinology and Internal Medicine MEA, Aarhus University Hospital THG, Tage Hansens Gade 2, 8000 Aarhus C, Denmark
    Calcif Tissue Int 90:22-9. 2012
    ..The finding may be spurious due to the "healthy user" effect, but a causal relationship cannot be excluded...
  67. ncbi request reprint Hyperthyroidism, bone mineral, and fracture risk--a meta-analysis
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    Thyroid 13:585-93. 2003
    ..Upon normalization of the hyperthyroid state BMD return to normal even though no specific antiosteoporotic measures are taken other than normalizing the hyperthyroid state...
  68. ncbi request reprint Fractures in patients with hyperthyroidism and hypothyroidism: a nationwide follow-up study in 16,249 patients
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aahus Amtssygehus, Aarhus University Hospital, Denmark
    Thyroid 12:411-9. 2002
    ..To study fracture risk in patients with hyperthyroidism and hypothyroidism...
  69. ncbi request reprint Fracture risk is increased in patients with GH deficiency or untreated prolactinomas--a case-control study
    Peter Vestergaard
    Department of Endocrinology, Aarhus Amtssygehus, Medical Department M Endocrinology and Diabetes, Aarhus Kommunehospital, Aarhus, University Hospital, Aarhus, Denmark
    Clin Endocrinol (Oxf) 56:159-67. 2002
    ..The aim of this study was to examine fracture risk in patients with pituitary disorders with special reference to GH deficiency and hyperprolactinaemia...
  70. ncbi request reprint Smoking as a risk factor for Graves' disease, toxic nodular goiter, and autoimmune hypothyroidism
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Denmark
    Thyroid 12:69-75. 2002
    ..In conclusion, smoking is a powerful risk factor for thyroid disease, especially in populations with a high smoking frequency. Oral contraceptive use is associated with a slightly lower frequency of Graves' disease...
  71. ncbi request reprint Prevalence and pathogenesis of osteoporosis in patients with inflammatory bowel disease
    P Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    Minerva Med 95:469-80. 2004
    ..Despite the limited excess fracture risk, a relatively large percentage of all fractures may be attributable to corticosteroid use among users of corticosteroids...
  72. ncbi request reprint Increased risk of osteoporotic fractures in patients with Cushing's syndrome
    Peter Vestergaard
    The Osteoporosis Clinic, Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Tage Hansens Gade 2, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 146:51-6. 2002
    ..To evaluate if fracture risk was increased in patients with Cushing's syndrome due to the increased endogenous cortisol production...
  73. ncbi request reprint Fracture risk associated with systemic and topical corticosteroids
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus, Denmark
    J Intern Med 257:374-84. 2005
    ..To study the fracture risk associated with the use of corticosteroids in any formulation and administration...
  74. ncbi request reprint Bone loss associated with gastrointestinal disease: prevalence and pathogenesis
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Tage Hansens Gade 2, DK 8000 Aarhus C, Denmark
    Eur J Gastroenterol Hepatol 15:851-6. 2003
    ..Reduced bone mineral density is thus prevalent in these individuals and is compounded by age related bone loss, leading to the development of severe bone disease in some patients...
  75. ncbi request reprint [Glucocorticoid-induced osteoporosis. Occurrence, prophylaxis and treatment]
    Peter Vestergaard
    Arhus Universitetshospital, Arhus Sygehus, Medicinsk Endokrinologisk Afdeling C
    Ugeskr Laeger 167:898-900. 2005
  76. ncbi request reprint Fractures in patients with anorexia nervosa, bulimia nervosa, and other eating disorders--a nationwide register study
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    Int J Eat Disord 32:301-8. 2002
    ..To study fracture risk in patients with anorexia nervosa (AN), bulimia nervosa (BN), or eating disorders not otherwise specified (EDNOS)...
  77. ncbi request reprint Fractures in patients with primary idiopathic hypothyroidism
    P Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Denmark
    Thyroid 10:335-40. 2000
    ..To study fracture risk and risk factors for fractures in patients with primary idiopathic hypothyroidism (ICD 10: E03.9)...
  78. ncbi request reprint Fracture risk associated with use of antiepileptic drugs
    Peter Vestergaard
    Department of Endocrinology and Metabolism, Aarhus University Hospital, Aarhus Sygehus, Aarhus, Denmark
    Epilepsia 45:1330-7. 2004
    ..An increased fracture risk has been reported in patients with epilepsy. Classical AEDs have been associated with decreased bone mineral density. The effects of newer AEDs are unknown...
  79. ncbi request reprint Corticosteroid use and risk of hip fracture: a population-based case-control study in Denmark
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    J Intern Med 254:486-93. 2003
    ..To examine the association between cumulative CS dose and risk of hip fracture...
  80. ncbi request reprint Effects of 5 years of hormonal replacement therapy on menopausal symptoms and blood pressure-a randomised controlled study
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Tage Hansens Gade 2, DK 8000 C Aarhus, Denmark
    Maturitas 46:123-32. 2003
    ..To study the effects of hormonal replacement on hot flushes, other symptoms linked to menopause, and blood pressure...
  81. ncbi request reprint Fracture risk associated with smoking: a meta-analysis
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    J Intern Med 254:572-83. 2003
    ..To assess fracture risk associated with smoking...
  82. ncbi request reprint Parathyroid surgery is associated with a decreased risk of hip and upper arm fractures in primary hyperparathyroidism: a controlled cohort study
    P Vestergaard
    Department of Endocrinology and Metabolism Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    J Intern Med 255:108-14. 2004
    ..To study if parathyroid surgery reduced fracture risk in patients with primary hyperparathyroidism...
  83. ncbi request reprint Osteoporosis is markedly underdiagnosed: a nationwide study from Denmark
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Amtssygehus, Aarhus, Denmark
    Osteoporos Int 16:134-41. 2005
    ..To compare the number of patients diagnosed with osteoporosis and osteoporotic fractures in Denmark, with the number of subjects expected to have osteoporosis...
  84. ncbi request reprint [Cohort study on effects of parathyroid surgery in primary hyperparathyroidism]
    Peter Vestergaard
    Arhus Universitetshospital, Arhus Sygehus, Medicinsk Endokrinologisk Afdeling C
    Ugeskr Laeger 166:2807-10. 2004
  85. ncbi request reprint Cardiovascular events before and after surgery for primary hyperparathyroidism
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Tage Hansens Gade 2, DK 8000 Aarhus, Denmark
    World J Surg 27:216-22. 2003
    ..The risk of MI decreased to a normal level after surgery, which may be important for preventing cardiovascular disease in patients with primary hyperparathyroidism...
  86. ncbi request reprint Fractures in patients with primary hyperparathyroidism: nationwide follow-up study of 1201 patients
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Tage Hansens Gade 2, Aarhus University Hospital, DK 8000, Aarhus C, Denmark
    World J Surg 27:343-9. 2003
    ..58, 95% CI 0.47-0.73). No differences in fracture risk could be demonstrated between those who had and those who did not have surgery, taking age, gender, and previous fractures into account...
  87. ncbi request reprint [Secondary osteoporosis, epidemiology and risk factors]
    Peter Vestergaard
    Arhus Universitetshospital, Arhus Sygehus, Medicinsk Endokrinologisk Afdeling C
    Ugeskr Laeger 167:1020-6. 2005
  88. ncbi request reprint [Cinacalcet--a new drug for the treatment of secondary hyperparathyroidism in patients with uraemia, parathyroid cancer or primary hyperparathyroidism]
    Peter Vestergaard
    Osteoporoseklinikken, Arhus Universitetshospital, Arhus Sygehus, Medicinsk Endokrinologisk Afdeling C, Arhus C
    Ugeskr Laeger 168:29-32. 2006
    ..Cinacalcet decreases plasma calcium and plasma PTH levels in patients with primary hyperparathyroidism or parathyroid cancer...
  89. ncbi request reprint Fracture risk in patients treated for hyperthyroidism
    P Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Denmark
    Thyroid 10:341-8. 2000
    ..To study fracture risk and risk factors for fractures in patients with hyperthyroidism...
  90. pmc Cohort study of risk of fracture before and after surgery for primary hyperparathyroidism
    P Vestergaard
    Department of Endocrinology and Metabolism, Aarhus University Hospital, Aarhus Amtssygehus, Aarhus, Denmark
    BMJ 321:598-602. 2000
    ..To study whether fracture risk before and after surgery was increased in patients with primary hyperparathyroidism...
  91. ncbi request reprint Epilepsy, osteoporosis and fracture risk - a meta-analysis
    P Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Denmark
    Acta Neurol Scand 112:277-86. 2005
    ..05). The deficit in BMD in patients with epilepsy is too small to explain the observed increase in fracture risk. The remainder of the increase in fracture risk may be linked to seizures...
  92. ncbi request reprint Hip fracture prevention: cost-effective strategies
    P Vestergaard
    Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Aarhus University Hospital, Denmark
    Pharmacoeconomics 19:449-68. 2001
    ..Further studies comparing several hip fracture preventive regimens are required in order to establish the most cost-effective strategy...
  93. ncbi request reprint Fracture risk is decreased in acromegaly--a potential beneficial effect of growth hormone
    Peter Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Tage Hansens Gade 2, Aarhus, DK 8000, Denmark
    Osteoporos Int 15:155-9. 2004
    ..8, 95% CI: 4.7-29.3). In conclusion, fracture risk is significantly decreased in patients with acromegaly compared to controls probably due to an anabolic effect of growth hormone on bone...
  94. ncbi request reprint [Cohort study of fracture risk before and after surgery of primary hyperparathyroidism]
    P Vestergaard
    Arhus Universitetshospital, Arhus Amtssygehus, Medicinsk afdeling C, og kirurgisk afdeling L
    Ugeskr Laeger 163:4875-8. 2001
    ..Primary hyperparathyroidism may have started up to ten years before surgery, and the fracture risk is normalised after surgery...
  95. ncbi request reprint Influence of hyper- and hypothyroidism, and the effects of treatment with antithyroid drugs and levothyroxine on fracture risk
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus, Tage Hansens Gade 2, Aarhus, Denmark
    Calcif Tissue Int 77:139-44. 2005
    ..Low-dose levothyroxine was not associated with fracture risk. The effect of antithyroid drugs may be caused by the reduction in thyroid hormone levels...
  96. ncbi request reprint Reduced relative risk of fractures among users of lithium
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus Sygehus, Aarhus, Denmark
    Calcif Tissue Int 77:1-8. 2005
    ..Adjustment for further confounders did not change the results. Lithium treatment was associated with a decreased risk of fractures potentially pointing at bone anabolic properties...
  97. ncbi request reprint Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus, Denmark
    Diabetologia 48:1292-9. 2005
    ..We studied the association between fractures and type 1 and type 2 diabetes mellitus...
  98. ncbi request reprint Increased mortality in patients with a hip fracture-effect of pre-morbid conditions and post-fracture complications
    P Vestergaard
    Department of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
    Osteoporos Int 18:1583-93. 2007
    ..The main reason for the excess mortality was linked to the trauma that caused the hip fracture...
  99. ncbi request reprint [Treatment of osteoporosis with antiresorptive drugs]
    Peter Vestergaard
    Arhus Universitetshospital, Arhus Sygehus, Medicinsk Endokrinologisk Afdeling C
    Ugeskr Laeger 167:883-7. 2005
  100. ncbi request reprint Discordance between changes in bone mineral density measured at different skeletal sites in perimenopausal women--implications for assessment of bone loss and response to therapy: The Danish Osteoporosis Prevention Study
    B Abrahamsen
    Department of Endocrinology, Odense University Hospital, Denmark
    J Bone Miner Res 16:1212-9. 2001
    ..In conclusion, changes at the commonly measured sites are discordant, and DXA of the forearm is less useful than DXA of the hip or spine in determining the overall skeletal response to therapy or assessing bone loss in untreated women...
  101. ncbi request reprint Trends in incidence and mortality in the hospital diagnosis of atrial fibrillation or flutter in Denmark, 1980-1999
    Lars Frost
    Department of Cardiology, Aarhus Amtssygehus, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Int J Cardiol 103:78-84. 2005
    ..We undertook this study to examine recent trends in incidence and mortality in subjects with a hospital diagnosis of atrial fibrillation or flutter in Denmark from 1980 to 1999 by sex, 10-year age group and conditions of comorbidity...