Arne Svejgaard

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. ncbi The immunogenetics of multiple sclerosis
    Arne Svejgaard
    Department of Clinical Immunology, Section 7631, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100, Copenhagen, Denmark
    Immunogenetics 60:275-86. 2008
  2. ncbi [Tissue types]
    Arne Svejgaard
    Vaevstypelaboratoriet, Klinisk Immunologisk Afdeling 7631, H:S Rigshospitalet,
    Ugeskr Laeger 165:4834-6. 2003
  3. ncbi Graft rejection after hematopoietic cell transplantation with nonmyeloablative conditioning
    Tania N Masmas
    Allogeneic Hematopoietic Cell Transplantation Laboratory, Department of Hematology, Rigshospitalet, Copenhagen, Denmark
    Am J Hematol 83:563-9. 2008
  4. ncbi Deficiency of somatic hypermutation of immunoglobulin G transcripts is a better predictor of severe respiratory tract infections than lack of memory B cells in common variable immunodeficiency
    Lone Schejbel
    Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark
    J Clin Immunol 25:392-403. 2005
  5. ncbi Cytokine gene expression in peripheral blood mononuclear cells and alloreactivity in hematopoietic cell transplantation with nonmyeloablative conditioning
    Søren L Petersen
    The Lymphocyte Research Laboratory, Department of Hematology, Rigshospitalet, Copenhagen, Denmark
    Biol Blood Marrow Transplant 12:48-60. 2006
  6. ncbi Evaluation and automation of hematopoietic chimerism analysis based on real-time quantitative polymerase chain reaction
    Tania N Masmas
    Lymphocyte Research Laboratory, Department of Hematology, Rigshospitalet, Copenhagen, Denmark
    Biol Blood Marrow Transplant 11:558-66. 2005
  7. ncbi A functional polymorphism in the Eta-1 promoter is associated with allele specific binding to the transcription factor Sp1 and elevated gene expression
    Tina Hummelshoj
    Department of Clinical Immunology, University Hospital of Copenhagen Rigshospitalet, Blegdamsvej 9, DK2200 Copenhagen, N, Denmark
    Mol Immunol 43:980-6. 2006
  8. ncbi [Genetic epidemiology]
    Arne Svejgaard
    Klinisk Immunologisk Afdeling 7631, Rigshospitalet, Blegdamsvej 9,
    Ugeskr Laeger 165:927-9. 2003
  9. ncbi Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark
    Merete Pedersen
    Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    Arthritis Rheum 56:1446-53. 2007
  10. ncbi C1q deficiency in an Inuit family: identification of a new class of C1q disease-causing mutations
    Hanne Vibeke Marquart
    Dept of Clinical Immunology sect 7631, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Denmark
    Clin Immunol 124:33-40. 2007

Collaborators

Detail Information

Publications24

  1. ncbi The immunogenetics of multiple sclerosis
    Arne Svejgaard
    Department of Clinical Immunology, Section 7631, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100, Copenhagen, Denmark
    Immunogenetics 60:275-86. 2008
    ..It is estimated that the C allele of a single nucleotide polymorphism, rs6897932, within the alternative spliced exon 6 of IL7RA is involved in about 30% of MS cases...
  2. ncbi [Tissue types]
    Arne Svejgaard
    Vaevstypelaboratoriet, Klinisk Immunologisk Afdeling 7631, H:S Rigshospitalet,
    Ugeskr Laeger 165:4834-6. 2003
  3. ncbi Graft rejection after hematopoietic cell transplantation with nonmyeloablative conditioning
    Tania N Masmas
    Allogeneic Hematopoietic Cell Transplantation Laboratory, Department of Hematology, Rigshospitalet, Copenhagen, Denmark
    Am J Hematol 83:563-9. 2008
    ..Retransplantation is feasible and well tolerated after HCT with nonmyeloablative conditioning and should be performed without delay in patients with imminent and manifest graft rejection...
  4. ncbi Deficiency of somatic hypermutation of immunoglobulin G transcripts is a better predictor of severe respiratory tract infections than lack of memory B cells in common variable immunodeficiency
    Lone Schejbel
    Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark
    J Clin Immunol 25:392-403. 2005
    ..Patients with reduced concentrations of switched memory B cells had normal or low SHM, and only the IgG SHM fraction correlated with prediagnostic incidence of severe respiratory tract infections (P = 0.004)...
  5. ncbi Cytokine gene expression in peripheral blood mononuclear cells and alloreactivity in hematopoietic cell transplantation with nonmyeloablative conditioning
    Søren L Petersen
    The Lymphocyte Research Laboratory, Department of Hematology, Rigshospitalet, Copenhagen, Denmark
    Biol Blood Marrow Transplant 12:48-60. 2006
    ..03). In conclusion, a high IL-10 gene expression in the recipient MNCs may be related to a reduced incidence of acute GVHD grades II to IV and a reduced graft-versus-tumor effect after HCT with nonmyeloablative conditioning...
  6. ncbi Evaluation and automation of hematopoietic chimerism analysis based on real-time quantitative polymerase chain reaction
    Tania N Masmas
    Lymphocyte Research Laboratory, Department of Hematology, Rigshospitalet, Copenhagen, Denmark
    Biol Blood Marrow Transplant 11:558-66. 2005
    ..Furthermore, automated setup was feasible in a time-, labor-, and reagent-conserving manner...
  7. ncbi A functional polymorphism in the Eta-1 promoter is associated with allele specific binding to the transcription factor Sp1 and elevated gene expression
    Tina Hummelshoj
    Department of Clinical Immunology, University Hospital of Copenhagen Rigshospitalet, Blegdamsvej 9, DK2200 Copenhagen, N, Denmark
    Mol Immunol 43:980-6. 2006
    ....
  8. ncbi [Genetic epidemiology]
    Arne Svejgaard
    Klinisk Immunologisk Afdeling 7631, Rigshospitalet, Blegdamsvej 9,
    Ugeskr Laeger 165:927-9. 2003
    ....
  9. ncbi Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark
    Merete Pedersen
    Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    Arthritis Rheum 56:1446-53. 2007
    ....
  10. ncbi C1q deficiency in an Inuit family: identification of a new class of C1q disease-causing mutations
    Hanne Vibeke Marquart
    Dept of Clinical Immunology sect 7631, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Denmark
    Clin Immunol 124:33-40. 2007
    ..None of 100 healthy controls carried the mutation. Our findings define a third class of molecular mechanisms behind C1q deficiency, where missense mutations cause a lack of detectable C1q-antigen in serum...
  11. ncbi [Matching for ABO blood groups and HLA tissue types in transplantation with special reference to bone marrow transplantation]
    Bodil K Jakobsen
    Vaevstypelaboratoriet, Klinisk Immunologisk Afdeling 7631, H:S Rigshospitalet,
    Ugeskr Laeger 165:4837-9. 2003
  12. ncbi Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection in common variable immunodeficiency
    Pernille Andersen
    Department of Clinical Immunology, Blood Bank, University Hospital, Copenhagen, Copenhagen, Denmark
    Blood 105:511-7. 2005
    ..01). This suggests that most patients with CVID fail to recruit affinity-maturated B cells, adding a qualitative deficiency to the quantitative deficiency characterizing these patients...
  13. ncbi Concordance for disease course and age of onset in Scandinavian multiple sclerosis coaffected sib pairs
    Annette Bang Oturai
    Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Mult Scler 10:5-8. 2004
    ..The aim of this study was to investigate a possible genetic influence on selected demographic and clinical variables among familial Scandinavian MS cases...
  14. ncbi [Transplantation immunology]
    Ebbe Dickmeiss
    H:S Rigshospitalet, Diagnostisk Center, Klinisk-immunologisk Afdeling, Stamcellesektionen, Vaevstypelaboratoriet,
    Ugeskr Laeger 165:4831-3. 2003
  15. ncbi Mannose-binding lectin variant alleles and HLA-DR4 alleles are associated with giant cell arteritis
    Soren Jacobsen
    Department of Rheumatology, Hvidovre Hospital, Copenhagen, Denmark
    J Rheumatol 29:2148-53. 2002
    ....
  16. ncbi Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy
    Christian Siebold
    Division of Structural Biology, The Henry Wellcome Building for Genomic Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom
    Proc Natl Acad Sci U S A 101:1999-2004. 2004
    ..In narcolepsy, the volume of the P4 pocket appears central to the susceptibility, suggesting that the presentation of a specific peptide population plays a major role...
  17. ncbi Two genome-wide linkage disequilibrium screens in Scandinavian multiple sclerosis patients
    Hanne F Harbo
    Institute of Immunology, Rikshospitalet University Hospital, 0027 Oslo, Norway
    J Neuroimmunol 143:101-6. 2003
    ..Usable data were achieved from the same 3331 markers in both screens. Nine markers from eight genomic regions (1p33, 3q13, 6p21, 6q14, 7p22, 9p21, 9q21 and Xq22) were identified as potentially associated with MS in both screens...
  18. ncbi A functional and structural basis for TCR cross-reactivity in multiple sclerosis
    Heather L E Lang
    Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Nat Immunol 3:940-3. 2002
    ..This provides structural evidence for molecular mimicry involving HLA molecules. The structural details suggest an explanation for the preponderance of MHC class II associations in HLA-associated diseases...
  19. ncbi Nomenclature for factors of the HLA system, 2002
    Steven G E Marsh
    Anthony Nolan Research Institute, Royal Free Hospital, Hampstead, London, UK
    Eur J Immunogenet 29:463-515. 2002
  20. ncbi Nomenclature for factors of the HLA system, 2002
    Steven G E Marsh
    Anthony Nolan Research Institute, Royal Free Hospital, Hampstead, London, United Kingdom
    Hum Immunol 63:1213-68. 2002
  21. ncbi Limited protective effect of the CCR5Delta32/CCR5Delta32 genotype on human immunodeficiency virus infection incidence in a cohort of patients with hemophilia and selection for genotypic X4 virus
    Astrid K N Iversen
    Department of Medical Microbiology and Immunology, Arhus University School of Medicine, Denmark
    J Infect Dis 187:215-25. 2003
    ..Sequence comparisons indicate that X4 virus can be selected in vivo due to either absence of CCR5 receptors or relative increase of CXCR4 receptors...
  22. ncbi Immunogenetic heterogeneity in single-system and multisystem langerhans cell histiocytosis
    Cecilia Bernstrand
    Childhood Cancer Research Unit, Q6 05, Karolinska Hospital, S 171 76 Stockholm, Sweden
    Pediatr Res 54:30-6. 2003
    ..Further studies to confirm these findings are desired...
  23. ncbi Nomenclature for Factors of the HLA System, 2004
    Steven G E Marsh
    Anthony Nolan Research Institute, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, United Kingdom
    Hum Immunol 66:571-636. 2005
  24. ncbi Variant mannose-binding lectin genotypes and outcome in early versus late rheumatoid arthritis: comment on the article by Ip et al
    Niels A Graudal
    Gentofte University Hospital, Denmark
    Arthritis Rheum 46:555-6. 2002