Research Topics
Species | Rikke Riber-HansenSummaryAffiliation: Aarhus University Hospital Country: Denmark Publications
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Detail Information
Publications
Extensive pathological analysis of selected melanoma sentinel lymph nodes: high metastasis detection rates at reduced workloadRikke Riber-Hansen
Institute of Pathology, Aarhus University Hospital, Noerrebrogade 44, Aarhus C, 8000, Denmark
Ann Surg Oncol 15:1492-501. 2008..We aimed to design a protocol that reduced this workload without compromising metastasis detection...
Quantitative real-time RT-PCR in sentinel lymph nodes from melanoma patients. Detection of melanocytic mRNA predicts disease-free survivalRikke Riber-Hansen
Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark
APMIS 116:199-205. 2008..009). This suggests that the presence of submicroscopic metastases may influence prognosis, indicating that RT-PCR detection of melanocytic cells in SLNs may be an important diagnostic marker...
Automated digital volume measurement of melanoma metastases in sentinel nodes predicts disease recurrence and survivalRikke Riber-Hansen
Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark
Histopathology 59:433-40. 2011..However, it is somewhat laborious for routine application. Our aim was to investigate whether digital image analysis can estimate TMV accurately in melanoma SLNs...
Automated quantification of MART1-verified Ki67 indices by digital image analysis in melanocytic lesionsPatricia Switten Nielsen
Department of Pathology, Aarhus University Hospital, Noerrebrogade 44, Aarhus C, Denmark
Arch Pathol Lab Med 136:627-34. 2012..Instead, digital image analysis of Ki67/MART1 double stains may provide fast and novel index computations for entire tumor sections...
Treatment influencing down-staging in EORTC Melanoma Group sentinel node histological protocol compared with complete step-sectioning: a national multicentre studyRikke Riber-Hansen
Institute of Pathology, Aarhus University Hospital, Noerrebrogade 44, DK 8000 Aarhus, Denmark
Eur J Cancer 48:347-52. 2012..We performed a prospective multicentre study to compare the European Organisation for Research and Treatment of Cancer (EORTC) recommended protocol with a protocol of complete step-sectioning...
Stage migration after minor changes in histologic estimation of tumor burden in sentinel lymph nodes: the protocol trapRikke Riber-Hansen
Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark
Cancer 115:2177-87. 2009..Melanoma metastasis size estimates are of prognostic significance for groups of patients, but to the authors' knowledge, measurement consensus does not exist...
The nodal location of metastases in melanoma sentinel lymph nodesRikke Riber-Hansen
Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark
Am J Surg Pathol 33:1522-8. 2009..The design of melanoma sentinel lymph node (SLN) histologic protocols is based on the premise that most metastases are found in the central parts of the nodes, but the evidence for this belief has never been thoroughly tested...
Metastatic melanoma volume in sentinel nodes: objective stereology-based measurement predicts disease recurrence and survivalRikke Riber-Hansen
Institute of Pathology, Aarhus University Hospital, Aarhus University, Aarhus, Denmark
Histopathology 54:796-803. 2009..The aim was to use objective stereological techniques to correlate accurately total SLN tumour burden with recurrence and patient survival...
Tumor and inflammation markers in melanoma using tissue microarrays: a validation studyTrine Ollegaard Jensen
Department of Oncology, Aarhus University Hospital, Aarhus, Denmark
Melanoma Res 21:509-15. 2011..We conclude that TMA technology combined with simplified grading systems are appropriate for analyzing both inflammation and tumor cell markers in melanoma...
Immunohistochemical double stains against Ki67/MART1 and HMB45/MITF: promising diagnostic tools in melanocytic lesionsPatricia Switten Nielsen
Department of Pathology, Aarhus University Hospital, 8000 Aarhus, Denmark
Am J Dermatopathol 33:361-70. 2011..The IHC double stains may potentially reduce misinterpretations of melanomas in histopathology...
Proliferation indices of phosphohistone H3 and Ki67: strong prognostic markers in a consecutive cohort with stage I/II melanomaPatricia S Nielsen
Department of Pathology, Aarhus University Hospital, Aarhus, Denmark
Mod Pathol 26:404-13. 2013..This was particularly true for thick melanomas whereas no specific analyses for thin melanomas only could be performed...
Evaluation of BRAF mutation testing methodologies in formalin-fixed, paraffin-embedded cutaneous melanomasJohanne Lade-Keller
Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark
J Mol Diagn 15:70-80. 2013..CADMA and TaqMan may not require macrodissections for a reliable test. Therefore, the use of more sensitive methods may have a future in testing for BRAF mutations in clinical settings...
Digital image analysis: a review of reproducibility, stability and basic requirements for optimal resultsRikke Riber-Hansen
Institute of Pathology, Aarhus University Hospital, Denmark
APMIS 120:276-89. 2012....
