Mette Nørgaard

..VTEs may occur even in patients with low platelet count. The conclusion is therefore that clinicians should keep VTE in mind as a potential diagnosis in patients with chronic ITP...

..Maternal infection during pregnancy may be a risk factor for epilepsy in offspring. Use of antibiotics is a valid marker of infection...

..To examine the association of atypical and conventional antipsychotics with the risk of hospitalization for acute pancreatitis...

..To compare the risk of postpartum infections within 30 days after vaginal birth, emergency, or elective cesarean section (CS)...

..To assess 30-day mortality from bacteremia in relation to age and comorbidity and the association between age and mortality with increasing comorbidity...

..We examined the association between COPD and 30-day mortality following bleeding and perforation of a peptic ulcer...

..It is unknown whether a prior diagnosis of monoclonal gammopathy of undetermined significance (MGUS) affects cancer survival...

..We examined the association between the maternal use of fluconazole during pregnancy and the risk of congenital malformations...

..Mortality estimates did not change in relation to the time period between gastroenteritis and cancer. Salmonella/Campylobacter gastroenteritis prior to cancer was associated with neither the cancer stage nor a poorer prognosis...

..We concluded that use of pivmecillinam was associated with an increased risk of miscarriage, but the risk was not significantly (p=0.64) different from the risk associated with use of sulfamethizole...

..Human data on the teratogenicity of selective serotonin reuptake inhibitors (SSRIs) are limited. We examined the association between SSRI use during early pregnancy and the risk of congenital malformations in the offspring...

..We aimed to examine the association of age with short-term mortality after perforated and bleeding peptic ulcer and to determine the impact of comorbidity on this association...

..83 (95% CI: 0.46-1.50). Our data showed that self-reported maternal use of oral contraceptives during pregnancy was not associated with an increased risk of hypospadias in the offspring...

..To determine the impact of preexisting ischemic heart disease (IHD) and stroke on overall survival in prostate cancer patients...

..Patients with haematological malignancy had increased long-term risk of enquiring Salmonella or Campylobacter gastroenteritis...

..To examine the association between maternal use of oral contraceptives in early pregnancy and increased prevalence of hypospadias in male offspring...

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..7 (95% CI, 0.3-2.0) and the prevalence ratio of bone malformations was 2.2 (95% CI, 0.7-6.7). Our study raises the concern that prenatal fluoroquinolone exposure may be associated with an increased risk of bone malformations...

..3 (95% CI, 1.8-3.0). In summary, primary chronic ITP was associated with substantially increased long-term risk of infections, hemorrhagic episodes requiring hospitalization, hematologic malignancies, and mortality...

..Patients with multiple myeloma are at increased risk of venous thromboembolism (VTE), but little information is available on VTE risk in patients with the precursor condition monoclonal gammopathy of undetermined significance (MGUS)...

..Few population-based studies exist on incidence, risk of infection and mortality in hairy cell leukaemia (HCL)...

..To examine whether acute pancreatitis is associated with the use of postmenopausal hormonal replacement therapy in Danish women over 45 yr of age...

..In addition, this study does not suggest any risk differential between maternal exposure to loratadine and other antihistamines. However, the statistical precision of the risk estimates was low...

..We describe mortality in patients with prostate cancer with and without bone metastasis further characterized by skeletal related events...

..Little is known about temporal trends in the incidence and mortality associated with bacteremia in the general population...

..Therefore, our data suggest that the increased risk is related to confounding by lifestyle factors or the underlying depression...

..Few epidemiological data exist on SREs after primary diagnosis of BrCa and subsequent bone metastasis. We therefore estimated the incidence of bone metastases and SREs in newly-diagnosed BrCa patients in Denmark from 1999 through 2007...

..e., patients' perceived frailty) cause the physicians to use the procedure cautiously...

..Failure to control anal cancer and complications of treatment are alternative indications for colostomy. However, no data exist on cause-specific colostomy rates. We examined this in a cohort study...

..To examine the association between febrile seizures and cognitive performance in early adulthood...

..3), respectively. We found that increasing age was associated with increased mortality from bacteraemia in patients with haematological malignancies. An increased burden of comorbidity among the elderly did not explain this association...

..To the authors' knowledge, little information is available regarding the incidence of cholecystitis among patients with cancer...

..Therefore, our data challenge the hypothesis that valproic acid is an independent risk factor for acute pancreatitis...

..There are limited data describing how pre-existing heart failure affects mortality following pneumonia...

..Few longitudinal studies examined this issue. In a population-based setting, we studied changes in the incidence and prognosis of PLC and LMUO over time...

..Endocarditis may be a marker for bacteremia-associated occult cancer. Intensive antibiotic treatment in endocarditis is suggested to reduce long-term cancer risk. We examined these hypotheses in a nationwide cohort study...

..To assess the impact of obesity and diabetes on the risk of post-cesarean infections...

..19 (95% confidence interval [CI] 0.68-2.06), and in the entire pregnancy was OR 0.94 (95% CI 0.61-1.44). Self-reported maternal herpes labialis during pregnancy was not associated with a substantially increased risk of NTDs in infants...

..08 and 1.83. Thus, this study found that penicillin use and use of other antibiotics were similarly associated with increased risk of MS, suggesting that the underlying infections may be causally associated with MS...

..Our aim was to study possible changes in survival of patients with kidney cancer after implementation of two national Danish cancer plans...

..6 (95% CI, 1.1-2.2)] and MGUS with kappa light chain [1.4 (95% CI, 1.1-1.7)]. MGUS patients had an increased risk of fractures, which could not be explained by comorbidity, advanced age, gender or malignant transformation...

..Confounding by indication may have contributed to the increased risks, but the study provides no evidence to suggest that recent NSAID intake may be protective for lung cancer...

..Our aims were to examine the extent of disease at the time of the diagnosis of ovarian cancer and to estimate the impact of VTE on survival of ovarian cancer...

..The impact of comorbidity on the outcome of colorectal cancer is poorly understood. We examined the prevalence of comorbidity and its impact on survival among Danish colorectal cancer patients...

..We conducted this population-based study to monitor recent trends in colon and rectal cancer survival in the central and northern regions of Denmark...

..In this review, we describe patient-specific factors associated with the outcome of disease, the clinical course of immune thrombocytopenia including the potential adverse impact of some treatments and finally the overall prognosis...

..We therefore examined risk factors, use, and efficacy of prophylactic antibiotics for surgical site infection SSI among patients with uncomplicated open appendectomy...

..We examined whether diabetes increased 30-day mortality among Danish patients hospitalized with bleeding or perforated peptic ulcers...

..We therefore examined the changes in survival in Danish patients with colorectal carcinoma (CRC) or other solid tumors (non-CRC) who had liver metastases at time of diagnosis...

..24, 95% CI: 0.81-1.86). Thus, bone marrow reticulin and collagen content in chronic ITP patients may be associated with some clinical characteristics...

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..The aim was to examine predictors for and prevalence rates of nonadherence to maintenance treatment among women with UC prior to and during pregnancy...

..However, few updated longitudinal studies examined this issue. In a population-based setting, we studied changes in the prognoses over time...

..To compare microbial agents causing first episodes of bacteraemia in patients with and without haematological malignancies, and to examine mortality within 90 days of follow-up...

..accounted for 25% of the reports stating polar motility. In conclusion, we demonstrated a high accuracy of Gram stain reports, whereas wet mount microscopy was generally less accurate...

..Administrative data may be useful for epidemiological studies of chronic idiopathic thrombocytopenic purpura (ITP). However, the quality of the recorded diagnoses needs evaluation...

..Our aim was to examine possible changes in the short- and long-term survival of patients with prostate cancer during 1998-2009...

..As a result, in 2000, a national strategy to improve cancer survival was introduced. Here we examine time trends in survival and relative mortality among pancreatic cancer patients, using Danish population and medical databases...

..4 (CI: 2.1-40.8)). In conclusion, we found HIV infection, solid organ transplantation, haematologic malignancies and a range of specific autoimmune diseases strongly associated with increased risk of anal SCC...

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..79 (95% CI 0.38-1.68) for exposure within 28 d before delivery. Use of pivmecillinam during pregnancy did not appear to increase the risk of adverse birth and neonatal outcomes; however, statistical precision is still low...

..Compliance did not seem to be influenced by the patients' functional impairment or the MTX dose level...

..To describe patterns of prescribed drug use over time among primiparous women in Denmark...

..We aimed to examine possible changes in survival of Danish breast cancer patients in central and northern Denmark in the period 1998-2009...

..Data on the safety of selective serotonin-reuptake inhibitors (SSRIs) in pregnancy are inconsistent. We examined associations between SSRI use during early pregnancy and risk of congenital malformations in infants...

..To examine time trends of survival and mortality of ovarian cancer in the central and northern Denmark regions during the period 1998-2009...