Research Topics
Genomes and GenesSpecies | O MorsSummaryAffiliation: Aarhus University Hospital Country: Denmark Publications
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Detail Information
Publications
Effects of family history and place and season of birth on the risk of schizophreniaP B Mortensen
Department of Psychiatric Demography, Institute for Basic Psychiatric Research, Psychiatric Hospital, Aarhus University Hospital, Risskov, Denmark
N Engl J Med 340:603-8. 1999..Although a family history of schizophrenia is the best-established risk factor for schizophrenia, environmental factors such as the place and season of birth may also be important...
A genome-wide search for risk genes using homozygosity mapping and microarrays with 1,494 single-nucleotide polymorphisms in 22 eastern Cuban families with bipolar disorderH Ewald
Centre for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, Risskov, Denmark
Am J Med Genet B Neuropsychiatr Genet 133:25-30. 2005..When analyzing 19 additional microsatellite markers on chromosome 17q the maximum parametric multipoint LOD score was 2.08, 1.5 cM proximal to D17S668. The present study replicates a recent significant linkage finding...
A genome-wide search for alleles and haplotypes associated with autism and related pervasive developmental disorders on the Faroe IslandsM B Lauritsen
Centre for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, Aarhus University Hospital, Shovagervej 2, DK 8240 Risskov, Denmark
Mol Psychiatry 11:37-46. 2006..Our data suggest that markers in these regions are in linkage disequilibrium with genes involved in the etiology of autism, and we hypothesize susceptibility genes for autism and related PDDs to be localized within these regions...
Further evidence for a bipolar risk gene on chromosome 12q24 suggested by investigation of haplotype sharing and allelic association in patients from the Faroe IslandsB Degn
Department of Biological Psychiatry, Institute for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, DK-8240 Risskov, Denmark
Mol Psychiatry 6:450-5. 2001..This area contains the minimum interesting region between D12S342 and D12S1658 suggested by the previously reported haplotypes in the two Danish families with bipolar affective disorder...
A functional variant of the serotonin transporter gene in families with bipolar affective disorderH Ewald
Department of Psychiatric Demography, Institute for Basic Psychiatric Research, Risskov, Denmark
J Affect Disord 48:135-44. 1998..Recently a functionally important 44 basepair deletion in the regulatory region of the SERT gene was described. Association between this variant and affective disorder has been suggested...
Possible evidence for a common risk locus for bipolar affective disorder and schizophrenia on chromosome 4p16 in patients from the Faroe IslandsT D Als
Department of Psychiatric Demography, Institute for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, Aarhus University Hospital, Risskov, Denmark
Mol Psychiatry 9:93-8. 2004..Our study yields support for a common risk gene for schizophrenia and bipolar affective disorder on the short arm of chromosome 4, as suggested by previous findings in the neighbouring Scottish population...
Mutational screening and association study of glutamate decarboxylase 1 as a candidate susceptibility gene for bipolar affective disorder and schizophreniaM D Lundorf
Centre for Basic Psychiatric Research, Psychiatric University Hospital in Aarhus, Risskov, Denmark
Am J Med Genet B Neuropsychiatr Genet 135:94-101. 2005..Thus the results obtained from the Scottish sample suggest that the GAD1 gene variants do not play a major role in the predisposition to schizophrenia...
Support for the possible locus on chromosome 4p16 for bipolar affective disorderH Ewald
Department of Psychiatric Demography, Psychiatric Hospital in Aarhus, Denmark
Mol Psychiatry 3:442-8. 1998..Final proof of a disease locus in the Scottish and our study has to await the identification of a DNA sequence of functional significance for bipolar disorder...
Decreased risk of acute appendicitis in patients with schizophrenia or manic-depressive psychosisH Ewald
Department of Psychiatric Demography, Institute for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, University Hospital, Skovagervej 2, DK 8240, Risskov, Denmark
Schizophr Res 49:287-93. 2001..Further studies of this relationship may help to clarify etiological or pathophysiological aspects of schizophrenia and manic-depressive psychosis...
A haplotype-based study of lithium responding patients with bipolar affective disorder on the Faroe IslandsH Ewald
Department of Psychiatric Demography, Psychiatric Hospital in Aarhus, Denmark
Psychiatr Genet 9:23-34. 1999..However, methods of genetic analysis which might provide a conclusive result are not yet available...
Empirical support for a reclassification of eating disorders NOSJ L Helverskov
Eating Disorder Centre, Regional Centre of Child and Adolescent Psychiatry, Aarhus University Hospital, Risskov, Denmark
Eur Eat Disord Rev 19:303-15. 2011..To explore the empirical support for a reclassification of the eating disorders NOS (EDNOS) category...
A population-based register study of the association between schizophrenia and rheumatoid arthritisO Mors
Department of Psychiatric Demography, Institute for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, Risskov, Denmark
Schizophr Res 40:67-74. 1999..Clinicians are reminded of the difficulties in detecting medical illness among individuals with schizophrenia...
Susceptibility loci for bipolar affective disorder on chromosome 18? A review and a study of Danish familiesH Ewald
Department of Psychiatric Demography, Psychiatric Hospital in Aarhus, Denmark
Psychiatr Genet 7:1-12. 1997..The highest lod score found was for marker D18S67, 1.83 at 0.05 recombination fraction...
A genome-wide scan shows significant linkage between bipolar disorder and chromosome 12q24.3 and suggestive linkage to chromosomes 1p22-21, 4p16, 6q14-22, 10q26 and 16p13.3H Ewald
Department of Psychiatric Demography, Institute for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, Skovagervej, Risskov, Denmark
Mol Psychiatry 7:734-44. 2002..60 (P-value 0.00079) at D1S216 further supported this finding. A number of additional loci on chromosomes 4p16, 6q14-q22, 10q26 and 16p13.3 yielded parametric lod scores around or above 2...
Is head injury a risk factor for schizophrenia?A S Nielsen
Department of Psychiatric Demography, Institute for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, Skovagervej 2, 8240 Risskov, Denmark
Schizophr Res 55:93-8. 2002..The few studies that have examined whether head injury is a risk factor for later schizophrenia have had important methodological problems...
No evidence of increased risk for schizophrenia or bipolar affective disorder in persons with aneuploidies of the sex chromosomesO Mors
Department of Pschiatric Demography, Institute for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, Denmark
Psychol Med 31:425-30. 2001....
Search for common haplotypes on chromosome 22q in patients with schizophrenia or bipolar disorder from the Faroe IslandsT H Jorgensen
Institute for Basic Psychiatric Research, Department of Psychiatric Demography, Psychiatric Hospital in Aarhus, Aarhus University Hospital, Aarhus, Denmark
Am J Med Genet 114:245-52. 2002..We did not find this mutation in schizophrenic or bipolar patients or the controls from the Faroe Islands...
The perceived and predicted implications of psychiatric genetic knowledge among persons with multiple cases of depression in the familyM M Laegsgaard
Centre for Psychiatric Research, Aarhus Psychiatric University Hospital, Risskov, Denmark
Acta Psychiatr Scand 122:470-80. 2010....
The norepinephrine transporter gene is a candidate gene for panic disorderH N Buttenschøn
Centre for Psychiatric Research, Aarhus University Hospital, Risskov, Skovagervej 2, 8240 Risskov, Denmark
J Neural Transm 118:969-76. 2011..Furthermore, the NET gene showed overall evidence for association with the disease (P = 0.000035). In conclusion, the present study indicates that NET could be a susceptibility gene for PD...
Trans-diagnostic outcome of eating disorders: A 30-month follow-up study of 629 patientsJ L Helverskov
Eating Disorder Centre, Regional Centre of Child and Adolescent Psychiatry, Aarhus University Hospital, Risskov, Denmark
Eur Eat Disord Rev 18:453-63. 2010..To assess the 30-month outcome and predictors of outcome in a cohort of patients with any eating disorder (ED)...
