C E Mogensen

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. ncbi request reprint The kidney in diabetes: how to control renal and related cardiovascular complications
    C E Mogensen
    Medical Department M, Aarhus Kommunehospital, Aarhus University Hospital, Aarhus, Denmark
    Am J Kidney Dis 37:S2-6. 2001
  2. pmc Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microalbuminuria (CALM) study
    C E Mogensen
    Department of Medicine, M, Kommunehospitalet, University Hospital, DK 8000 Aarhus C, Denmark
    BMJ 321:1440-4. 2000
  3. ncbi request reprint Normal blood pressure and preserved diurnal variation in offspring of type 2 diabetic patients characterized by features of the metabolic syndrome: the Fredericia Study
    C H Foss
    Medical Department, Diabetes and Endocrinology, Aarhus Kommunehospital, Aarhus University Hospital, Denmark
    Diabetes Care 23:283-9. 2000
  4. ncbi request reprint Losartan modifies glomerular hyperfiltration and insulin sensitivity in type 1 diabetes
    S Nielsen
    Medical Department M Endocrinology and Diabetes, Aarhus Kommunehospital, Aarhus, Denmark
    Diabetes Obes Metab 3:463-71. 2001
  5. ncbi request reprint Autonomic neuropathy in nondiabetic offspring of type 2 diabetic subjects is associated with urinary albumin excretion rate and 24-h ambulatory blood pressure: the Fredericia Study
    C H Foss
    Medical Department M, Diabetes and Endocrinology, Aarhus Kommunehospital, Aarhus University Hospital, Denmark
    Diabetes 50:630-6. 2001
  6. ncbi request reprint Early ACE-i intervention in microalbuminuric patients with type 1 diabetes: effects on albumin excretion, 24 h ambulatory blood pressure, and renal function
    P L Poulsen
    Medical Department M, Diabetes and Endocrinology, Aarhus, Denmark
    Diabetes Metab 27:123-8. 2001
  7. ncbi request reprint No deleterious effects of tight blood glucose control on 24-hour ambulatory blood pressure in normoalbuminuric insulin-dependent diabetes mellitus patients
    P L Poulsen
    Medical Department M Diabetes and Endocrinology, Aarhus Kommunehospital, Denmark
    J Clin Endocrinol Metab 85:155-8. 2000
  8. ncbi request reprint Endothelial dysfunction, ambulatory pulse pressure and albuminuria are associated in Type 2 diabetic subjects
    S T Knudsen
    Medical Department M Diabetes and Endocrinology, Aarhus University Hospital, Aarhus, Denmark
    Diabet Med 24:911-5. 2007
  9. ncbi request reprint What is hypertension in diabetes? Ambulatory blood pressure in 137 normotensive and normoalbuminuric Type 1 diabetic patients
    K W Hansen
    Medical Department M, Aarhus Kommunehospital, Aarhus, Denmark
    Diabet Med 18:370-3. 2001
  10. ncbi request reprint Effects of metoprolol on QT interval and QT dispersion in Type 1 diabetic patients with abnormal albuminuria
    E Ebbehøj
    Medical Department M Diabetes and Endocrinology, Kommunehospitalet, Aarhus University Hospital, 8000 Aarhus C, Denmark
    Diabetologia 47:1009-15. 2004

Detail Information

Publications43

  1. ncbi request reprint The kidney in diabetes: how to control renal and related cardiovascular complications
    C E Mogensen
    Medical Department M, Aarhus Kommunehospital, Aarhus University Hospital, Aarhus, Denmark
    Am J Kidney Dis 37:S2-6. 2001
    ..Conversely, ACE inhibitors may have some diabetes-protective effect, but further studies are needed...
  2. pmc Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microalbuminuria (CALM) study
    C E Mogensen
    Department of Medicine, M, Kommunehospitalet, University Hospital, DK 8000 Aarhus C, Denmark
    BMJ 321:1440-4. 2000
    ..To assess and compare the effects of candesartan or lisinopril, or both, on blood pressure and urinary albumin excretion in patients with microalbuminuria, hypertension, and type 2 diabetes...
  3. ncbi request reprint Normal blood pressure and preserved diurnal variation in offspring of type 2 diabetic patients characterized by features of the metabolic syndrome: the Fredericia Study
    C H Foss
    Medical Department, Diabetes and Endocrinology, Aarhus Kommunehospital, Aarhus University Hospital, Denmark
    Diabetes Care 23:283-9. 2000
    ..To examine whether an elevated blood pressure (BP) level and an impaired reduction in nocturnal BP are already present in nondiabetic first-degree relatives of type 2 diabetic patients...
  4. ncbi request reprint Losartan modifies glomerular hyperfiltration and insulin sensitivity in type 1 diabetes
    S Nielsen
    Medical Department M Endocrinology and Diabetes, Aarhus Kommunehospital, Aarhus, Denmark
    Diabetes Obes Metab 3:463-71. 2001
    ....
  5. ncbi request reprint Autonomic neuropathy in nondiabetic offspring of type 2 diabetic subjects is associated with urinary albumin excretion rate and 24-h ambulatory blood pressure: the Fredericia Study
    C H Foss
    Medical Department M, Diabetes and Endocrinology, Aarhus Kommunehospital, Aarhus University Hospital, Denmark
    Diabetes 50:630-6. 2001
    ..This study indicates that parental type 2 diabetes has an impact on the cardiac autonomic function in nondiabetic subjects...
  6. ncbi request reprint Early ACE-i intervention in microalbuminuric patients with type 1 diabetes: effects on albumin excretion, 24 h ambulatory blood pressure, and renal function
    P L Poulsen
    Medical Department M, Diabetes and Endocrinology, Aarhus, Denmark
    Diabetes Metab 27:123-8. 2001
    ..To study the effects of ACE-i in type 1 diabetic patients with early microalbuminuria with regard to: i) UAE, ii) 24 h AMBP, including the effect on diurnal BP variation, and iii) renal haemodynamics...
  7. ncbi request reprint No deleterious effects of tight blood glucose control on 24-hour ambulatory blood pressure in normoalbuminuric insulin-dependent diabetes mellitus patients
    P L Poulsen
    Medical Department M Diabetes and Endocrinology, Aarhus Kommunehospital, Denmark
    J Clin Endocrinol Metab 85:155-8. 2000
    ..Intensive therapy can be implemented without concerns of inducing high nocturnal BP and accelerating diabetic complications...
  8. ncbi request reprint Endothelial dysfunction, ambulatory pulse pressure and albuminuria are associated in Type 2 diabetic subjects
    S T Knudsen
    Medical Department M Diabetes and Endocrinology, Aarhus University Hospital, Aarhus, Denmark
    Diabet Med 24:911-5. 2007
    ..The relation between endothelial dysfunction and PP in diabetic subjects has not previously been examined. We examined the relation between PP, markers of endothelial activation and albuminuria in Type 2 diabetic patients...
  9. ncbi request reprint What is hypertension in diabetes? Ambulatory blood pressure in 137 normotensive and normoalbuminuric Type 1 diabetic patients
    K W Hansen
    Medical Department M, Aarhus Kommunehospital, Aarhus, Denmark
    Diabet Med 18:370-3. 2001
    ..To evaluate the statement of the third working party of the British Hypertension Society (BHS) that a target clinic BP in diabetes < 140/80 corresponds to a target day-time AMBP < 130/75 mmHg...
  10. ncbi request reprint Effects of metoprolol on QT interval and QT dispersion in Type 1 diabetic patients with abnormal albuminuria
    E Ebbehøj
    Medical Department M Diabetes and Endocrinology, Kommunehospitalet, Aarhus University Hospital, 8000 Aarhus C, Denmark
    Diabetologia 47:1009-15. 2004
    ..The aim of our study was to describe the effects of metoprolol treatment on QT interval and QT dispersion in a group of well-characterised Type 1 diabetic patients with elevated urine albumin excretion...
  11. ncbi request reprint Increased QTc dispersion is related to blunted circadian blood pressure variation in normoalbuminuric type 1 diabetic patients
    P L Poulsen
    Medical Department M Diabetes and Endocrinology, Aarhus Kommunehospital, Denmark
    Diabetes 50:837-42. 2001
    ..This coexistence may be operative in the ability of these parameters to predict cardiovascular events...
  12. doi request reprint Ambulatory pulse pressure, decreased nocturnal blood pressure reduction and progression of nephropathy in type 2 diabetic patients
    S T Knudsen
    Medical Department M Diabetes and Endocrinology, Aarhus University Hospital, Nørrebrogade 44, 8000, Aarhus C, Denmark
    Diabetologia 52:698-704. 2009
    ..We followed type 2 diabetic patients over a long period to evaluate the predictive value of ambulatory pulse pressure (PP) and decreased nocturnal BP reduction (non-dipping) for nephropathy progression...
  13. ncbi request reprint Antihypertensive treatment: long-term reversal of progression of albuminuria in incipient diabetic nephropathy. A longitudinal study of renal function
    C K Christensen
    Second University Clinic of Internal Medicine, Kommunehospitalet, Aarhus C, Denmark
    J Diabet Complications 1:45-52. 1987
    ..0% (mean +/- SD); during treatment urinary albumin excretion decreased 19 +/- 10% per year (2p = 0.7%). No changes were seen in renal plasma flow (516 +/- 31.0 ml/min to 520 +/- 66 ml/min (n = 5)).(ABSTRACT TRUNCATED AT 250 WORDS)..
  14. ncbi request reprint Combination of enalapril and low-dose thiazide reduces normoalbuminuria in essential hypertension
    S Nielsen
    Medical Department M, Aarhus Kommunehospital, Denmark
    J Hypertens 16:1539-44. 1998
    ..A secondary objective was to compare the effects of the two regimens in patients with different levels of albuminuria...
  15. ncbi request reprint Diabetic renal disease: from recent studies to improved clinical practice
    C E Mogensen
    Medical Department M, Aarhus Kommunehospital, Aarhus, Denmark
    Diabet Med 21:4-17. 2004
  16. ncbi request reprint Microalbuminuria and hypertension with focus on type 1 and type 2 diabetes
    C E Mogensen
    Medical Department M, Aarhus Kommunehospital, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    J Intern Med 254:45-66. 2003
    ..Before that time it was suggested, mainly from the US, that diabetic renal disease was an untreatable relentlessly progressive condition...
  17. ncbi request reprint Effects of felodipine on urinary albumin excretion and metabolic control in hypertensive non-insulin-dependent diabetics
    A Schmitz
    Second University Clinic of Internal Medicine Kommunehospitalet, Aarhus, Denmark
    Am J Hypertens 3:611-7. 1990
    ..Since microalbuminuria predicts proteinuria and reduced survival, early antihypertensive treatment may be beneficial in NIDDM as it is in IDDM. Long-term consequences on kidney function and mortality remains, however, to be elucidated...
  18. ncbi request reprint Characteristics and prognosis of normoalbuminuric type 1 diabetic patients
    P L Poulsen
    Medical Department M Diabetes and Endocrinology, Aarhus Kommunehospital, Denmark
    Diabetes Care 22:B72-5. 1999
    ....
  19. ncbi request reprint NT-proBNP in normoalbuminuric patients with Type 2 diabetes mellitus
    N H Andersen
    Department of Internal Medicine M, Diabetes and Endocrinology, Aarhus University Hospital, Denmark
    Diabet Med 22:188-95. 2005
    ..To examine levels of NT-proBNP and its relation to hypertension, as well as diastolic function in normoalbuminuric patients with Type 2 diabetes...
  20. ncbi request reprint New concepts in blood pressure-lowering management in diabetic patients: the case for early ACE inhibitor combination therapy with diuretics
    C E Mogensen
    Aarhus University Hospital, Nørrebrogade, Aarhus, Denmark
    J Hum Hypertens 19:S15-20. 2005
    ..Cardiovascular events showed a decreased incidence with the combination therapy with Preterax (perindopril/indapamide) compared with the enalapril group...
  21. pmc Relation between plasma amino-terminal propeptide of procollagen type III and left ventricular longitudinal strain in essential hypertension
    S H Poulsen
    Department of Cardiology, Skejby Hospital, Aarhus University Hospital, DK 8200 Aarhus N, Denmark
    Heart 91:624-9. 2005
    ..To investigate whether myocardial fibrosis assessed non-invasively is related to left ventricular (LV) longitudinal systolic function in patients with essential hypertension...
  22. ncbi request reprint Increased plasma concentrations of osteoprotegerin in type 2 diabetic patients with microvascular complications
    S T Knudsen
    Medical Department M Diabetes Endocrinology, Institute of Pathology, Aarhus Kommunehospital, Aarhus University Hospital, Aarhus, Denmark
    Eur J Endocrinol 149:39-42. 2003
    ..The aim of the present study was to examine the association between plasma OPG levels and microvascular complications and glycemic control in patients with type 2 diabetes...
  23. ncbi request reprint Effects of losartan on diabetic maculopathy in type 2 diabetic patients: a randomized, double-masked study
    S T Knudsen
    Department of Medical M Diabetes and Endocrinology, Aarhus Kommunehospital, Aarhus, Denmark
    J Intern Med 254:147-58. 2003
    ..We evaluated the effect of treatment with the angiotensin II receptor antagonist losartan on macular oedema and hard exudates in patients with an advanced stage of DMa...
  24. ncbi request reprint Plasma concentrations of osteoprotegerin during normo- and hyperglycaemic clamping
    S T Knudsen
    Medical Department M Diabetes and Endocrinology, Aarhus University Hospital, Aarhus, Denmark
    Scand J Clin Lab Invest 67:135-42. 2007
    ..The aim of the present study was to examine the effect of acute hyperglycaemia on plasma levels of OPG in non-diabetic subjects...
  25. ncbi request reprint Lisinopril reduces albuminuria during exercise in low grade microalbuminuric type 1 diabetic patients: a double blind randomized study
    P L Poulsen
    Medical Department, Aarhus Kommunehospital, Aarhus, Denmark
    J Intern Med 249:433-40. 2001
    ..In addition, the possible predictive effect of baseline E-UAE on the progression of overnight UAE remains to be clarified...
  26. ncbi request reprint Effects of smoking on 24-h ambulatory blood pressure and autonomic function in normoalbuminuric insulin-dependent diabetes mellitus patients
    P L Poulsen
    Medical Department M Diabetes and Endocrinology, Aarhus University Hospital, Denmark
    Am J Hypertens 11:1093-9. 1998
    ..Blood pressure elevation, persisting throughout 24 h, might be operative in the association between smoking and development of diabetic nephropathy...
  27. ncbi request reprint E-selectin-inducing activity in plasma from type 2 diabetic patients with maculopathy
    S T Knudsen
    Medical Department M Diabetes and Endocrinology, Institute of Pathology, Aarhus University Hospital, Denmark
    Am J Physiol Endocrinol Metab 284:E1-6. 2003
    ..Enhanced expression of E-selectin may contribute to the development of DMa in type 2 diabetes...
  28. ncbi request reprint High normo- or low microalbuminuria: basis for intervention in insulin-dependent diabetes mellitus
    P L Poulsen
    Department of Medicine M Diabetes and Endocrinology, Aarhus Kommunehospital, Denmark
    Kidney Int Suppl 63:S15-8. 1997
    ..ACEi intervention in selected normoalbuminuric high risk patients (high-normal UAE, high-normal blood pressure, and poor glycemic control) would be of interest...
  29. ncbi request reprint The reno-protective role of AT(1)-receptor blockers
    C E Mogensen
    Aarhus University Hospital, Denmark
    J Hum Hypertens 16:S52-8. 2002
    ..In certain situations, there may be a slight, readily reversible, increase in serum potassium. There may also be a slight reduction in GFR, reflecting a decrease in glomerular filtration pressure...
  30. ncbi request reprint Impact of essential hypertension and diabetes mellitus on left ventricular systolic and diastolic performance
    N H Andersen
    Department of Internal Medicine Diabetes and Endocrinology, Aarhus University Hospital, Denmark
    Eur J Echocardiogr 4:306-12. 2003
    ..To investigate left ventricular systolic and diastolic function in patients with essential hypertension and diabetes mellitus associated with hypertension by the myocardial performance index (MPI)...
  31. ncbi request reprint What is the relevance of the HOPE study in general practice?
    J Kennedy
    Medical Department M Diabetes and Endocrinology, Aarhus Kommunehospital, Denmark
    Int J Clin Pract 55:449-57. 2001
    ..The effectiveness of therapy should also be regularly reviewed and dose adjustments made where necessary. If concern remains, referral to a specialist--a cardiologist or a diabetologist--may ultimately be necessary...
  32. ncbi request reprint Decreased left ventricular longitudinal contraction in normotensive and normoalbuminuric patients with Type II diabetes mellitus: a Doppler tissue tracking and strain rate echocardiography study
    N H Andersen
    Department of Internal Medicine, Diabetes and Endocrinology, Aarhus University Hospital, Nørrebrogade 44, Aarhus C 8000, Denmark
    Clin Sci (Lond) 105:59-66. 2003
    ....
  33. ncbi request reprint Effects on heart rate variability of metoprolol supplementary to ongoing ACE-inhibitor treatment in Type I diabetic patients with abnormal albuminuria
    E Ebbehøj
    Medical Department M, Diabetes and Endocrinology, Kommunehospitalet, Aarhus University Hospital, Denmark
    Diabetologia 45:965-75. 2002
    ....
  34. ncbi request reprint Insulin resistance is accompanied by increased von Willebrand factor levels in nondiabetic women: a study of offspring of type 2 diabetic subjects compared to offspring of nondiabetic subjects
    C H Foss
    Medical Department M, Diabetes and Endocrinology, Aarhus Kommunehospital, Aarhus University Hospital, Aarhus, Denmark
    J Intern Med 252:155-63. 2002
    ..To examine whether levels of von Willebrand factor (vWF), fibrinogen and fibronectin are related to a parental history of type 2 diabetes and to determine possible explanatory factors for high versus low vWF and fibrinogen...
  35. ncbi request reprint Poor prognosis in proteinuric type 2 diabetic patients with retinopathy: insights from the RENAAL study
    H H Parving
    Steno Diabetes Center, Niels Steensensvej 2, DK 2820 Gentofte, Denmark
    QJM 98:119-26. 2005
    ..Retinopathy is the clinical hallmark of generalized microangiopathy in diabetes...
  36. ncbi request reprint Reduction in albuminuria translates to reduction in cardiovascular events in hypertensive patients with left ventricular hypertrophy and diabetes
    H Ibsen
    Department of Cardiology, Holbaek Hospital, Holbaek Denmark
    J Nephrol 21:566-9. 2008
    ..Reduction in albuminuria during treatment translates to reduction in cardiovascular events. Monitoring of albuminuria should be an integrated part of management of hypertension in diabetic as well as nondiabetic patients...
  37. ncbi request reprint Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial
    Anushka Patel
    Cardiovascular Division, The George Institute for International Health, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW 2050, Australia
    Lancet 370:829-40. 2007
    ....
  38. ncbi request reprint Comparison of the combination of enalapril and a very low dose of hydrochlorothiazide with atenolol in patients with mild-to-moderate hypertension. Scandinavian Study Group
    I Os
    Department of Medicine, Ullevaal University Hospital, Oslo, Norway
    Am J Hypertens 10:899-904. 1997
    ..019); there was a trend toward more patients achieving target diastolic BP (<90 mm Hg, P = .053). No clinically important differences in safety and tolerability were observed...
  39. doi request reprint Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    Anushka Patel
    N Engl J Med 358:2560-72. 2008
    ..In patients with type 2 diabetes, the effects of intensive glucose control on vascular outcomes remain uncertain...
  40. ncbi request reprint Ambulatory blood pressure monitoring
    K W Hansen
    Diabet Med 20:509; author reply 509. 2003
  41. ncbi request reprint Left ventricular dysfunction in hypertensive patients with Type 2 diabetes mellitus
    N H Andersen
    Medical Department M Diabetes and Endocrinology Aarhus University Hospital, Denmark
    Diabet Med 22:1218-25. 2005
    ..To characterize left ventricular function in hypertensive patients with Type 2 diabetes and normal ejection fraction, and to relate these findings to pathogenic factors and clinical risk markers...
  42. ncbi request reprint Increased plasma adiponectin in losartan-treated type 1 diabetic patients. a mediator of improved insulin sensitivity?
    S Nielsen
    Medical Departments of Endocrinology and Diabetes, Aarhus University Hospitals, Denmark
    Horm Metab Res 36:194-6. 2004
  43. ncbi request reprint Peripheral vascular disease is associated with reduced glycosuria in newly diagnosed type 2 diabetic patients
    N de Fine Olivarius
    Central Research Unit and Department of General Practice, University of Copenhagen Panum Institute, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Diabetes Metab 30:269-74. 2004
    ..We examined whether the finding of glycosuria and its level in themselves give information of clinical relevance, apart from being an unreliable indicator of glycemic control...