Research Topics
| R W LichtSummaryAffiliation: Aarhus University Hospital Country: Denmark Publications
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Detail Information
Publications
Fixed-dosed risperidone in mania: an open experimental trialR W Licht
Mood Disorders Research Unit, Aarhus University Psychiatric Hospital, Risskov, Denmark
Int Clin Psychopharmacol 16:103-10. 2001..Side-effect profiles were rather similar in the two treatment groups. Despite design limitations, these findings may justify the conduction of randomized controlled trials to investigate the use of risperidone in mania...
Are antidepressants safe in the treatment of bipolar depression? A critical evaluation of their potential risk to induce switch into mania or cycle accelerationR W Licht
Mood Disorders Research Unit, Aarhus University Hospital, Risskov, Denmark
Acta Psychiatr Scand 118:337-46. 2008....
Long-term outcome of patients with bipolar disorder commenced on lithium prophylaxis during hospitalization: a complete 15-year register-based follow-upRasmus W Licht
Mood Disorders Research Unit, Aarhus University Psychiatric Hospital, Risskov, Denmark
Bipolar Disord 10:79-86. 2008..However, the effectiveness of lithium under routine conditions seems less pronounced. In the present study, the overall 15.3-year outcome in BD patients commenced on lithium is described...
[Prophylactic treatment of affective disorders]Rasmus Wentzer Licht
Arhus Universitetshospital, Klinik for Mani og Depression, Risskov
Ugeskr Laeger 169:1453-5. 2007..Even though none of the treatments cause dramatic risk reduction, it is often possible to improve the individual prognosis through integrated long-term management by specialized teams...
Validation of the Bech-Rafaelsen Melancholia Scale and the Hamilton Depression Scale in patients with major depression; is the total score a valid measure of illness severity?R W Licht
Mood Disorders Research Unit, Aarhus University Psychiatric Hospital, Risskov, Denmark
Acta Psychiatr Scand 111:144-9. 2005..On this background, we aimed at comparing the unidimensionality of the Bech-Rafaelsen Melancholia Scale (MES) and the 17-item Hamilton Depression Rating Scale (HAM-D(17))...
Chronic lithium treatment with or without haloperidol fails to affect the morphology of the rat cerebellumR W Licht
Mood Disorders Research Unit, Aarhus University Psychiatric Hospital, Skovagervej 2, DK 8240 Risskov, Denmark
Eur Neuropsychopharmacol 13:173-6. 2003..After 30 weeks of treatment, the animals were killed and the cerebelli were histologically prepared. No statistically significant differences were observed between the groups with respect to the cerebellar measures...
[Psychopharmacological treatment of bipolar disease]Rasmus W Licht
Forskningsafdeling for Affektive Sygdomme, Psykiatrisk Hospital i Arhus, Arhus Universitetshospital, DK 8240 Risskov
Ugeskr Laeger 164:2495-7. 2002..However, for several reasons, for instance treatment failure or side effects, long-term treatment with antiepileptics may often be necessary. Among the antiepileptics, carbamazepine, valproate, and lamotrigine are the best studied...
Treatment strategies in patients with major depression not responding to first-line sertraline treatment. A randomised study of extended duration of treatment, dose increase or mianserin augmentationRasmus W Licht
Mood Disorders Research Unit, Aarhus University Psychiatric Hospital, 8240 Risskov, Denmark
Psychopharmacology (Berl) 161:143-51. 2002..A large proportion of patients with major depression do not respond sufficiently to any first-line treatment...
Limitations in randomised controlled trials evaluating drug effects in maniaR W Licht
Mood Disorders Research Unit, Aarhus University Psychiatric Hospital, Risskov, Denmark
Eur Arch Psychiatry Clin Neurosci 251:II66-71. 2001..These studies maybe randomised but open and use simple but relevant outcome measures...
Lack of interaction between sertraline and lamotrigine in psychiatric patients: a retrospective studyJ Christensen
Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
Pharmacopsychiatry 45:119-21. 2012..This study evaluates the pharmacokinetic interaction between sertraline and lamotrigine in psychiatric patients...
Risk factors of suicide in inpatients and recently discharged patients with affective disorders. A case-control studyE H Høyer
Psychiatric Hospital in Aarhus, University of Aarhus, Skovagervej 2, DK 8240 Risskov, Denmark
Eur Psychiatry 24:317-21. 2009..Patients with affective disorders are at high risk of suicide, especially during inpatient treatment and during the first year after discharge...
50 Years with lithium treatment in affective disorders: present problems and prioritiesP Vestergaard
Mood Disorders Research Unit, Aarhus University Psychiatric Hospital, Skovagervej 2, 8240 Risskov, Denmark
World J Biol Psychiatry 2:18-26. 2001..Finally, although not the main purpose of this review, a short description of alternative mood stabilizing drugs will also be presented...
A lithium clinic for bipolar patients: 2-year outcome of the first 148 patientsR W Licht
Mood Disorders Research Unit, Aarhus University Psychiatric Hospital, Skovagervej 2, DK-8240 Risskov, Denmark
Acta Psychiatr Scand 104:387-90. 2001..Better long-term treatment results for bipolar patients depend on both the development of more effective mood stabilizing drugs or drug combinations and the improvement of patients' adherence to treatment...
Acute and continuation therapy in unipolar depression: observations from the run-in phase of a maintenance trialL F Gram
Clinical Pharmacology, IST, University of Southern Denmark, Winsløwparken 19, DK 5000 Odense C, Denmark
Acta Psychiatr Scand 118:123-9. 2008..The aim of the study was to analyze treatments and outcome in depressed patients...
Under-recruitment of patients for clinical trials: an illustrative example of a failed studyJ M Rendell
Acta Psychiatr Scand 115:337-9. 2007
[Mortality in patients with affective disorder who commenced treatment with lithium. A 16-year follow-up]A Brodersen
Psykiatrisk Hospital, Arhus Universitetshospital, DK-8240 Risskov
Ugeskr Laeger 163:6428-32. 2001..DISCUSSION: Mortality, particularly death from suicide, was significantly increased in unselected affective disorder patients, who commenced lithium treatment, as compared with the background population...
