Majken K Jensen

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. ncbi request reprint Alcohol consumption, TaqIB polymorphism of cholesteryl ester transfer protein, high-density lipoprotein cholesterol, and risk of coronary heart disease in men and women
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Eur Heart J 29:104-12. 2008
  2. doi request reprint Obesity, behavioral lifestyle factors, and risk of acute coronary events
    Majken K Jensen
    Department of Clinical Epidemiology, Aarhus University Hospital, Sdr Skovvej 15, DK 9100 Aalborg, Denmark
    Circulation 117:3062-9. 2008
  3. ncbi request reprint Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA, United States
    Atherosclerosis 195:e172-80. 2007
  4. pmc S447X variant of the lipoprotein lipase gene, lipids, and risk of coronary heart disease in 3 prospective cohort studies
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am Heart J 157:384-90. 2009
  5. pmc Paraoxonase 1 polymorphisms and risk of myocardial infarction in women and men
    Kenneth J Mukamal
    Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Circ J 73:1302-7. 2009
  6. pmc Prospective study of breakfast eating and incident coronary heart disease in a cohort of male US health professionals
    Leah E Cahill
    Harvard School of Public Health, 655 Huntington Ave, Bldg II, Room 349, Boston, MA 02115, USA
    Circulation 128:337-43. 2013
  7. pmc Whole grains and incident hypertension in men
    Alan J Flint
    Department of Epidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Clin Nutr 90:493-8. 2009
  8. ncbi request reprint Whole grains, bran, and germ in relation to homocysteine and markers of glycemic control, lipids, and inflammation 1
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 83:275-83. 2006
  9. pmc Haptoglobin genotype is a consistent marker of coronary heart disease risk among individuals with elevated glycosylated hemoglobin
    Leah E Cahill
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts
    J Am Coll Cardiol 61:728-37. 2013
  10. pmc The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations
    Majken K Jensen
    Department of Clinical Epidemiology, Aarhus University Hospital, Aalborg, Denmark
    Eur Heart J 30:1584-9. 2009

Detail Information

Publications40

  1. ncbi request reprint Alcohol consumption, TaqIB polymorphism of cholesteryl ester transfer protein, high-density lipoprotein cholesterol, and risk of coronary heart disease in men and women
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Eur Heart J 29:104-12. 2008
    ..To investigate whether a common polymorphism in the cholesteryl ester transfer protein (CETP) gene modifies the relationship of alcohol intake with high-density lipoprotein cholesterol (HDL-C) and risk of coronary heart disease (CHD)...
  2. doi request reprint Obesity, behavioral lifestyle factors, and risk of acute coronary events
    Majken K Jensen
    Department of Clinical Epidemiology, Aarhus University Hospital, Sdr Skovvej 15, DK 9100 Aalborg, Denmark
    Circulation 117:3062-9. 2008
    ..Whether physical activity reduces the impact of obesity on the risk of acute coronary events is much debated. However, little is known about the role of other potentially modifiable lifestyle factors in combination with obesity...
  3. ncbi request reprint Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA, United States
    Atherosclerosis 195:e172-80. 2007
    ..Neither the -17C/G SNP nor the 2 the coding polymorphisms were associated with risk of CHD. The -565C/T and the -191G/C variants were inversely associated with risk of CHD among healthy women, without pronounced effects on plasma lipids...
  4. pmc S447X variant of the lipoprotein lipase gene, lipids, and risk of coronary heart disease in 3 prospective cohort studies
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am Heart J 157:384-90. 2009
    ..To provide deeper insight into the role of natural variation in this gene, we investigated the association between the LPL S447X variant with lipids and risk of coronary heart disease (CHD) in 3 independent, prospective studies...
  5. pmc Paraoxonase 1 polymorphisms and risk of myocardial infarction in women and men
    Kenneth J Mukamal
    Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Circ J 73:1302-7. 2009
    ..Previous studies of genetic variants of paraoxonase 1 (PON1) and coronary heart disease (CHD) have been conflicting and the modifying effects of lifestyle factors that affect PON1 activity are uncertain...
  6. pmc Prospective study of breakfast eating and incident coronary heart disease in a cohort of male US health professionals
    Leah E Cahill
    Harvard School of Public Health, 655 Huntington Ave, Bldg II, Room 349, Boston, MA 02115, USA
    Circulation 128:337-43. 2013
    ..However, it remains unknown whether specific eating habits regardless of dietary composition influence coronary heart disease (CHD) risk. The objective of this study was to prospectively examine eating habits and risk of CHD...
  7. pmc Whole grains and incident hypertension in men
    Alan J Flint
    Department of Epidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Clin Nutr 90:493-8. 2009
    ..Prospective data on the relation between whole grain intake and incident hypertension in men are limited, and no previous studies have quantitatively estimated total grams of whole grains in relation to risk of hypertension...
  8. ncbi request reprint Whole grains, bran, and germ in relation to homocysteine and markers of glycemic control, lipids, and inflammation 1
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 83:275-83. 2006
    ..The lower risk associated with high whole-grain intakes may be mediated through improvements in glycemic control, lipid profiles, or reduced inflammation...
  9. pmc Haptoglobin genotype is a consistent marker of coronary heart disease risk among individuals with elevated glycosylated hemoglobin
    Leah E Cahill
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts
    J Am Coll Cardiol 61:728-37. 2013
    ..This study sought to investigate into the biologically plausible interaction between the common haptoglobin (Hp) polymorphism rs#72294371 and glycosylated hemoglobin (HbA(1c)) on risk of coronary heart disease (CHD)...
  10. pmc The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations
    Majken K Jensen
    Department of Clinical Epidemiology, Aarhus University Hospital, Aalborg, Denmark
    Eur Heart J 30:1584-9. 2009
    ..The objective of this study was to address the associations of the T111I variant with plasma lipids and risk of CHD in three independent prospective studies of generally healthy men and women...
  11. pmc Interaction between obesity and the NFKB1 - 94ins/delATTG promoter polymorphism in relation to incident acute coronary syndrome: a follow up study in three independent cohorts
    Jakob Gerhard Stegger
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    PLoS ONE 8:e63004. 2013
    ....
  12. pmc Genetic predisposition to high blood pressure associates with cardiovascular complications among patients with type 2 diabetes: two independent studies
    Qibin Qi
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Diabetes 61:3026-32. 2012
    ..22 [95% CI 1.10-1.35] vs. 1.10 [1.08-1.12]; I² = 71%). Our data indicate that genetic predisposition to high blood pressure is associated with an increased risk of CVD in individuals with T2D...
  13. pmc Sugar-sweetened beverages and genetic risk of obesity
    Qibin Qi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 367:1387-96. 2012
    ..Temporal increases in the consumption of sugar-sweetened beverages have paralleled the rise in obesity prevalence, but whether the intake of such beverages interacts with the genetic predisposition to adiposity is unknown...
  14. doi request reprint Fish intake and acute coronary syndrome
    Lone J Bjerregaard
    Department of Cardiology, Aalborg Hospital, Aarhus University Hospital, Sdr Skovvej 15, 9000 Aalborg, Denmark
    Eur Heart J 31:29-34. 2010
    ..To study the effect of fish consumption on the risk of acute coronary syndrome (ACS) in healthy subjects...
  15. doi request reprint Predictive values of acute coronary syndrome discharge diagnoses differed in the Danish National Patient Registry
    Albert Marni Joensen
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Sdr Skovvej 15, DK 9000 Aalborg, Denmark
    J Clin Epidemiol 62:188-94. 2009
    ..To investigate the predictive value of acute coronary syndrome (ACS) diagnoses, including unstable angina pectoris, myocardial infarction, and cardiac arrest, in the Danish National Patient Registry...
  16. doi request reprint Fried food consumption, genetic risk, and body mass index: gene-diet interaction analysis in three US cohort studies
    Qibin Qi
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    BMJ 348:g1610. 2014
    ..To examine the interactions between genetic predisposition and consumption of fried food in relation to body mass index (BMI) and obesity...
  17. ncbi request reprint Drinking frequency, mediating biomarkers, and risk of myocardial infarction in women and men
    Kenneth J Mukamal
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Circulation 112:1406-13. 2005
    ....
  18. pmc Vigorous physical activity, mediating biomarkers, and risk of myocardial infarction
    Andrea K Chomistek
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Med Sci Sports Exerc 43:1884-90. 2011
    ..The degree to which these and other traditional and nontraditional cardiovascular biomarkers mediate the inverse association between physical activity and risk of MI in men remains unclear...
  19. pmc Fetuin-A, type 2 diabetes, and risk of cardiovascular disease in older adults: the cardiovascular health study
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Diabetes Care 36:1222-8. 2013
    ..Preliminary studies suggest that the association of fetuin-A with CVD might differ among individuals with or without type 2 diabetes...
  20. pmc Common FABP4 genetic variants and plasma levels of fatty acid binding protein 4 in older adults
    Kenneth J Mukamal
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Lipids 48:1169-75. 2013
    ..These results demonstrate associations of common SNP and haplotypes in the FABP4 gene with lower plasma FABP4 but higher fasting glucose levels. ..
  21. pmc Protein interaction-based genome-wide analysis of incident coronary heart disease
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circ Cardiovasc Genet 4:549-56. 2011
    ..We aimed to examine if networks of genes that represent experimentally determined protein-protein interactions (PPIs) are enriched in genes associated with risk of coronary heart disease (CHD)...
  22. pmc Fluorescent oxidation products and risk of coronary heart disease: a prospective study in women
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA
    J Am Heart Assoc 2:e000195. 2013
    ..The objective of this study is to determine whether measures of FlOPs are associated with risk of CHD in women over an extended follow-up period...
  23. pmc Association between alcohol consumption and plasma fetuin-A and its contribution to incident type 2 diabetes in women
    Sylvia H Ley
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA, 02115, USA
    Diabetologia 57:93-101. 2014
    ..We therefore hypothesised that moderate alcohol consumption would be associated with lower fetuin-A concentration and that fetuin-A would partly explain the association between alcohol consumption and incident type 2 diabetes...
  24. pmc ASIP genetic variants and the number of non-melanoma skin cancers
    Wen Lin
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Cancer Causes Control 22:495-501. 2011
    ..32; 95% CI, 1.07-1.63). The OR increased to 1.45(1.18-1.78) for those with 2-4 NMSCs and 1.84(1.34-2.53) for those with at least five. The findings suggest that ASIP locus is associated with the number of NMSCs...
  25. pmc Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption
    Marilyn C Cornelis
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Genet 7:e1002033. 2011
    ..4 × 10(-19)), near AHR, and 15q24 (P = 5.2 × 10(-14)), between CYP1A1 and CYP1A2. Both the AHR and CYP1A2 genes are biologically plausible candidates as CYP1A2 metabolizes caffeine and AHR regulates CYP1A2...
  26. ncbi request reprint Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 80:1492-9. 2004
    ..However, methods for the assessment of whole-grain intake differ. Furthermore, any additional effects of added bran and germ, which are components of whole grains, have not been reported...
  27. ncbi request reprint Drinking pattern and mortality in middle-aged men and women
    Janne S Tolstrup
    Centre for Alcohol Research, National Institute of Public Health, Copenhagen, Denmark
    Addiction 99:323-30. 2004
    ..To address the prospective association between alcohol drinking pattern and all-cause mortality...
  28. pmc Prospective study of alcohol drinking patterns and coronary heart disease in women and men
    Janne Tolstrup
    Centre for Alcohol Research, National Institute of Public Health, Øster Farimagsgade 5, DK 1399 Copenhagen, Denmark
    BMJ 332:1244-8. 2006
    ..To determine the association between alcohol drinking patterns and risk of coronary heart disease in women and men...
  29. ncbi request reprint A prospective study of the association between smoking and later alcohol drinking in the general population
    Majken K Jensen
    Copenhagen Centre for Prospective Population Studies, Danish Epidemiology Science Centre at the Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Addiction 98:355-63. 2003
    ..To address the possible prospective association between smoking habits and risk of later heavy drinking in the adult population...
  30. ncbi request reprint [A prospective study of the association between smoking and later alcohol drinking in the Danish population]
    Majken K Jensen
    H S Kommunehospitalet, Institut for Sygdomsforebyggelse, Statens Institut for Folkesundhed, Center for Alkoholforskning, København
    Ugeskr Laeger 166:3718-22. 2004
  31. ncbi request reprint Nonlinear relation between alcohol intake and high-density lipoprotein cholesterol level: results from the Copenhagen City Heart Study
    Ditte Johansen
    Danish Epidemiologic Science Centre at the Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Alcohol Clin Exp Res 27:1305-9. 2003
    ....
  32. ncbi request reprint Intake of beer, wine and spirits and risk of heavy drinking and alcoholic cirrhosis
    Morten Grønbaek
    Centre for Alcohol Research, National Institute of Public Health, Copenhagen, Denmark
    Biol Res 37:195-200. 2004
    ..We conclude that moderate wine drinkers appear to be at lower risk of becoming heavy and excessive drinkers and that this may add to the explanation of the reported beverage-specific differences in morbidity and mortality...
  33. ncbi request reprint Lifetime and baseline alcohol intake and risk of colon and rectal cancers in the European prospective investigation into cancer and nutrition (EPIC)
    Pietro Ferrari
    International Agency for Research on Cancer IARC WHO, Lyon, France
    Int J Cancer 121:2065-72. 2007
    ..03, 95%CI=0.98-1.09). In this large European cohort, both lifetime and baseline alcohol consumption increase colon and rectum cancer risk, with more apparent risk increases for alcohol intakes greater than 30 g/day...
  34. ncbi request reprint Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
    Carlos A Gonzalez
    Department of Epidemiology, Catalan Institute of Oncology, Barcelona ICO IDIBELL, Spain
    Int J Cancer 118:2559-66. 2006
    ..Our study supports a possible protective role of vegetable intake in the intestinal type of GC and the ACO. Citrus fruit consumption may have a role in the protection against cardia GC and ACO...
  35. ncbi request reprint Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC)
    Carlos A Gonzalez
    Department of Epidemiology, Catalan Institute of Oncology, Barcelona, Spain
    J Natl Cancer Inst 98:345-54. 2006
    ..We examined the risks of gastric cancer and esophageal adenocarcinoma associated with meat consumption within the European Prospective Investigation Into Cancer and Nutrition (EPIC) cohort...
  36. ncbi request reprint Ethanol intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Sabine Rohrmann
    Division of Clinical Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Am J Epidemiol 164:1103-14. 2006
    ..Although there was no overall association between ethanol intake and risk of lung cancer, the authors cannot rule out a lower risk for moderate consumption and a possibly increased risk for high lifelong consumption...
  37. ncbi request reprint Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition
    Olga M Sinilnikova
    IARC, Lyon, France
    Cancer Epidemiol Biomarkers Prev 16:409-15. 2007
    ..However, they suggest a possible role of the ACC-alpha common sequence variants in susceptibility to breast cancer and encourage studies of other genes involved in fatty acid synthesis...
  38. doi request reprint Alcohol consumption and the risk for prostate cancer in the European Prospective Investigation into Cancer and Nutrition
    Sabine Rohrmann
    Division of Cancer Epidemiology C020, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 17:1282-7. 2008
    ..No statistically significant association was observed for alcohol intake from specific alcoholic beverages. Our results indicate no association between the consumption of alcohol and prostate cancer in this cohort of European men...
  39. doi request reprint CDH1 gene polymorphisms, smoking, Helicobacter pylori infection and the risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
    Mazda Jenab
    International Agency for Research on Cancer IARC WHO, Lyon, France
    Eur J Cancer 44:774-80. 2008
    ..However, three CDH1 polymorphisms in the same haplotype block, including the CDH1-160C/A, interacted with smoking to increase GC risk in smokers but not in never smokers. These findings should be confirmed in larger independent studies...
  40. ncbi request reprint Alcoholic beverage preference and risk of becoming a heavy drinker
    Majken K Jensen
    Copenhagen Centre for Prospective Population Studies, Danish Epidemiology Science Centre at the Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Epidemiology 13:127-32. 2002
    ..The aim of this study is to examine whether the risk of becoming a heavy or excessive drinker differs among individuals who prefer different types of alcoholic beverages...