Jørgen Ingerslev

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. pmc Consensus recommendations for the diagnosis and treatment of acquired hemophilia A
    Peter Collins
    Arthur Bloom Hemophilia centre, School of Medicine, Cardiff University, University Hospital of Wales, Cardiff, CF14 4XN, UK
    BMC Res Notes 3:161. 2010
  2. ncbi request reprint Pharmacovigilance studies in haemophilia
    J Ingerslev
    Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby Sygehus, Brendstrupgaardsvej, Aarhus N, Denmark
    Haemophilia 13:121-3. 2007
  3. doi request reprint Parallel use of by-passing agents in haemophilia with inhibitors: a critical review
    Jørgen Ingerslev
    Centre for Haemophilia and Thrombosis, University Hospital Skejby Aarhus, University of Aarhus, Aarhus, Denmark
    Br J Haematol 155:256-62. 2011
  4. ncbi request reprint [Fibrinogen substitution. Use in the treatment of bleeding due to lack of fibrinogen]
    Jørgen Ingerslev
    Klinisk Biokemisk Afdeling, Center for Haemofili og Trombose, Skejby Sygehus, Aarhus Universitetshospital, DK 8200 Arhus
    Ugeskr Laeger 167:2759-61. 2005
  5. ncbi request reprint Surgery in hemophilia. The general view: patient selection, timing, and preoperative assessment
    Jørgen Ingerslev
    Centre for Haemophilia and Thrombosis, Department of Orthopaedic Surgery, University Hospital Aarhus, Aarhus N, Denmark
    Semin Hematol 43:S23-6. 2006
  6. ncbi request reprint Use of recombinant factor VIIa for emergency reversal of anticoagulation
    J Ingerslev
    Centre for Hemophilia and Thrombosis, University Hospital Skejby, Denmark
    J Postgrad Med 53:17-22. 2007
  7. doi request reprint Combination of recombinant factor VIIa and fibrinogen corrects clot formation in primary immune thrombocytopenia at very low platelet counts
    Ole H Larsen
    Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby, Denmark
    Br J Haematol 160:228-36. 2013
  8. doi request reprint Whole blood coagulation in children with thrombocytopenia and the response to platelet replacement, recombinant factor VIIa, and a potent factor VIIa analogue
    Ole H Larsen
    Centre for Haemophilia and Thrombosis, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    Br J Haematol 144:99-106. 2009
  9. ncbi request reprint Reversal of the International Normalized Ratio with recombinant activated factor VII in central nervous system bleeding during warfarin thromboprophylaxis: clinical and biochemical aspects
    Benny Sørensen
    Center for Haemophilia and Thrombosis, Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, Denmark
    Blood Coagul Fibrinolysis 14:469-77. 2003
  10. doi request reprint Citrate artificially masks the haemostatic effect of recombinant factor VIIa in dilutional coagulopathy
    Christian Fenger-Eriksen
    Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, Aarhus N, 8200 Aarhus, Denmark
    Ann Hematol 88:255-60. 2009

Collaborators

Detail Information

Publications21

  1. pmc Consensus recommendations for the diagnosis and treatment of acquired hemophilia A
    Peter Collins
    Arthur Bloom Hemophilia centre, School of Medicine, Cardiff University, University Hospital of Wales, Cardiff, CF14 4XN, UK
    BMC Res Notes 3:161. 2010
    ..AHA usually presents to clinicians without prior experience of the disease, therefore diagnosis is frequently delayed and bleeds under treated...
  2. ncbi request reprint Pharmacovigilance studies in haemophilia
    J Ingerslev
    Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby Sygehus, Brendstrupgaardsvej, Aarhus N, Denmark
    Haemophilia 13:121-3. 2007
  3. doi request reprint Parallel use of by-passing agents in haemophilia with inhibitors: a critical review
    Jørgen Ingerslev
    Centre for Haemophilia and Thrombosis, University Hospital Skejby Aarhus, University of Aarhus, Aarhus, Denmark
    Br J Haematol 155:256-62. 2011
    ....
  4. ncbi request reprint [Fibrinogen substitution. Use in the treatment of bleeding due to lack of fibrinogen]
    Jørgen Ingerslev
    Klinisk Biokemisk Afdeling, Center for Haemofili og Trombose, Skejby Sygehus, Aarhus Universitetshospital, DK 8200 Arhus
    Ugeskr Laeger 167:2759-61. 2005
    ..Acquired fibrinogen deficiency may occur with a variety of underlying pathologies. Fibrinogen substitution may be done with fresh-frozen plasma, cryoprecipitate and virally inactivated concentrates of fibrinogen...
  5. ncbi request reprint Surgery in hemophilia. The general view: patient selection, timing, and preoperative assessment
    Jørgen Ingerslev
    Centre for Haemophilia and Thrombosis, Department of Orthopaedic Surgery, University Hospital Aarhus, Aarhus N, Denmark
    Semin Hematol 43:S23-6. 2006
    ..In this overview, we will address issues related to surgery in hemophilic patients, as well as some practical issues related to the timing of surgery, preoperative testing, perioperative hemostasis, and patient rehabilitation...
  6. ncbi request reprint Use of recombinant factor VIIa for emergency reversal of anticoagulation
    J Ingerslev
    Centre for Hemophilia and Thrombosis, University Hospital Skejby, Denmark
    J Postgrad Med 53:17-22. 2007
    ..Aims: To identify and describe characteristics of subjects who received rFVIIa as part of emergency treatment aimed at improving hemostasis...
  7. doi request reprint Combination of recombinant factor VIIa and fibrinogen corrects clot formation in primary immune thrombocytopenia at very low platelet counts
    Ole H Larsen
    Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby, Denmark
    Br J Haematol 160:228-36. 2013
    ..These data suggest that rFVIIa combined with fibrinogen corrects the coagulopathy of ITP even at very low platelet counts, and may represent an alternative to platelet transfusion...
  8. doi request reprint Whole blood coagulation in children with thrombocytopenia and the response to platelet replacement, recombinant factor VIIa, and a potent factor VIIa analogue
    Ole H Larsen
    Centre for Haemophilia and Thrombosis, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    Br J Haematol 144:99-106. 2009
    ..Compromised platelet function in the study group was assumingly responsible for the weakened haemostatic potential of rFVIIa as well as that of NN1731...
  9. ncbi request reprint Reversal of the International Normalized Ratio with recombinant activated factor VII in central nervous system bleeding during warfarin thromboprophylaxis: clinical and biochemical aspects
    Benny Sørensen
    Center for Haemophilia and Thrombosis, Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, Denmark
    Blood Coagul Fibrinolysis 14:469-77. 2003
    ..The ex-vivo experiments and our clinical data support recent suggestions that rFVIIa might substitute for infusion of FFP or PCC in acute reversal of VKA treatment...
  10. doi request reprint Citrate artificially masks the haemostatic effect of recombinant factor VIIa in dilutional coagulopathy
    Christian Fenger-Eriksen
    Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, Aarhus N, 8200 Aarhus, Denmark
    Ann Hematol 88:255-60. 2009
    ..The effect in vitro of rFVIIa in citrated blood samples may underestimate the haemostatic potential of rFVIIa...
  11. doi request reprint Diagnostic performance and therapeutic consequence of thromboelastometry activated by kaolin versus a panel of specific reagents
    Ole Halfdan Larsen
    Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby, Denmark
    Anesthesiology 115:294-302. 2011
    ....
  12. ncbi request reprint Factor VIIa analogue (V158D/E296V/M298Q-FVIIa) normalises clot formation in whole blood from patients with severe haemophilia A
    Benny Sørensen
    Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby, Aarhus N, Denmark
    Br J Haematol 137:158-65. 2007
    ..Altogether, these in vitro studies on WB revealed a favourable haemostatic potential of NN1731 compared with rFVIIa in severe haemophilia A, both in the absence and presence of enhanced fibrinolytic activity...
  13. ncbi request reprint A direct thrombin inhibitor studied by dynamic whole blood clot formation. Haemostatic response to ex-vivo addition of recombinant factor VIIa or activated prothrombin complex concentrate
    Benny Sørensen
    Center for Haemophilia and Thrombosis, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    Thromb Haemost 96:446-53. 2006
    ..The pronounced stabilizing effect of APCC may be caused by its content of prothrombin and activated coagulation factors...
  14. ncbi request reprint Recombinant activated factor VIIa in uncontrolled bleeding: a haemostasis laboratory study in non-haemophilia patients
    Søren Brandsborg
    Faculty of Health Sciences, Aarhus University Hospital, Skejby, Denmark
    Blood Coagul Fibrinolysis 17:241-9. 2006
    ..With quite low doses of recombinant factor VIIa (<or= 60 microg/kg), the dose of recombinant factor VIIa correlated positively with efficacy. Activation of factor X appeared to predict haemostatic efficacy...
  15. doi request reprint Coagulopathy during induced severe intracranial hypertension in a porcine donor model
    Anne Barklin
    Department of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark
    Anesthesiology 110:1287-92. 2009
    ..The authors investigated dynamic whole-blood clot formation (ROTEM) in a recently developed porcine model of induced severe intracranial hypertension...
  16. ncbi request reprint Antibodies to heterologous proteins in hemophilia A patients receiving recombinant factor VIII (Recombinate)
    Jørgen Ingerslev
    Center for Hemophilia and Thrombosis, Department of Clinical Immunology, University Hospital Skejby, Aarhus, Denmark
    Thromb Haemost 87:626-34. 2002
    ..These data indicate that sustained immune responses to trace levels of heterologous proteins are very infrequent during long-term rhFVIII therapy...
  17. doi request reprint Fibrinogen concentrate--a potential universal hemostatic agent
    Christian Fenger-Eriksen
    Aarhus University Hospital, Department of Anaesthesiology, Skejby, Brendstrupgaardsvej 100, DK 8200 Aarhus N, Denmark
    Expert Opin Biol Ther 9:1325-33. 2009
    ....
  18. doi request reprint Fibrinogen estimates are influenced by methods of measurement and hemodilution with colloid plasma expanders
    Christian Fenger-Eriksen
    Department of Anaesthesiology and the Center for Haemophilia and Thrombosis, Aarhus University Hospital, Denmark
    Transfusion 50:2571-6. 2010
    ....
  19. ncbi request reprint Recurrent thromboembolism in ovarian cancer
    Jens Fuglsang
    Center for Haemophilia and Thrombosis, Skejby Sygehus, Aarhus University Hospital, Aarhus, Denmark
    Acta Obstet Gynecol Scand 83:1218-20. 2004
  20. ncbi request reprint Whole blood laboratory model of thrombocytopenia for use in evaluation of hemostatic interventions
    Ole Halfdan Larsen
    Center for Haemophilia and Thrombosis, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Aarhus N, Denmark
    Ann Hematol 86:217-21. 2007
    ..The WB model appears useful in research, development, and evaluation of the effects of hemostatic interventions in thrombocytopenia...
  21. ncbi request reprint The effect of long-term methylprednisolone treatment on the femoral head in growing pigs
    Wolf Drescher
    Department of Orthopaedics, Aarhus University Hospital, Denmark
    J Orthop Res 20:662-8. 2002
    ..Long-term steroid treatment did not produce FH necrosis or FH IOP alterations in the immature pig model...