Hans Jurgen Hoffmann

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. pmc Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria
    Claus Uhrenholt Christensen
    Allergy Center for West Denmark, Aarhus University Hospital, Aarhus, Denmark Department of Pulmonary Medicine, Aarhus University Hospital, Aarhus, Denmark
    Ann Dermatol 25:522-3. 2013
  2. pmc Research needs in allergy: an EAACI position paper, in collaboration with EFA
    Nikolaos G Papadopoulos
    Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
    Clin Transl Allergy 2:21. 2012
  3. doi request reprint Cultured human mast cells are heterogeneous for expression of the high-affinity IgE receptor FcεRI
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Aarhus University and Hospital, Aarhus, Denmark
    Int Arch Allergy Immunol 157:246-50. 2012
  4. pmc Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapy
    Susan Mikkelsen
    Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Denmark
    Clin Mol Allergy 8:2. 2010
  5. doi request reprint Human skin keratins are the major proteins in exhaled breath condensate
    H J Hoffmann
    Dept of Respiratory Diseases, Aarhus University Hospital, Denmark
    Eur Respir J 31:380-4. 2008
  6. doi request reprint Mast cell FcϵRI density and function dissociate from dependence on soluble IgE concentration at very low and very high IgE concentrations
    Inge Kortekaas Krohn
    Department of Respiratory Medicine, Aarhus University Hospital, Aarhus, Denmark
    J Asthma 50:117-21. 2013
  7. doi request reprint Comparison of short term in vitro cultured human mast cells from different progenitors - Peripheral blood-derived progenitors generate highly mature and functional mast cells
    Hanne Busk Andersen
    Department of Paediatrics, Aarhus University Hospital, DK 8200 Aarhus N, Denmark
    J Immunol Methods 336:166-74. 2008
  8. doi request reprint Seven week culture of functional human mast cells from buffy coat preparations
    Mette Holm
    Department of Human Genetics, University of Aarhus, DK 8000 Aarhus C, Denmark
    J Immunol Methods 336:213-21. 2008
  9. doi request reprint Pretreatment IgE sensitization patterns determine the molecular profile of the IgG4 response during updosing of subcutaneous immunotherapy with timothy grass pollen extract
    Johannes Martin Schmid
    Departments of Respiratory Medicine and Allergy, Aarhus University Hospital, Aarhus, Denmark
    J Allergy Clin Immunol 137:562-70. 2016
  10. doi request reprint Asthmatics able to step down from inhaled corticosteroid treatment without loss of asthma control have low serum eotaxin/CCL11
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Arhus University Hospital, Denmark
    Clin Respir J 2:149-57. 2008

Collaborators

  • Ronald Dahl
  • Christine Dahl
  • Mette Holm
  • Martin Raithel
  • Johannes Martin Schmid
  • Inge Kortekaas Krohn
  • Claus Uhrenholt Christensen
  • Nikolaos G Papadopoulos
  • Peter Oluf Schiøtz
  • Susan Mikkelsen
  • Susan Hansen
  • Hanne Busk Andersen
  • Peter Adler Würtzen
  • Pernille Munk Frandsen
  • Gitte Lund
  • Christian Vestergaard
  • Carina Venter
  • Odilija Rudzeviciene
  • Omer Kalayci
  • Monika Raulf-Heimsoth
  • Graham Roberts
  • Susanne Lau
  • Adriano Mari
  • Francois Spertini
  • Cansin Sackesen
  • Claudia Traidl-Hoffmann
  • Santiago Quirce
  • Zeljka Roje
  • Andrea Siracusa
  • Antoine Magnan
  • Adnan Custovic
  • Ioana Agache
  • Markus Ollert
  • Jurgen Schwarze
  • Lars Olaf Cardell
  • Paula Robson-Ansley
  • Filippo Fassio
  • Philippe Gevaert
  • Moises Calderon
  • Joanna Makowska
  • Ronald Vanree
  • Montserrat Fernandez Rivas
  • Enrico Heffler
  • Mariana Couto
  • Knut Brockow
  • Ingrid Terreehorst
  • Fulvio Braido
  • Marcin Kurowski
  • Carsten Flohr
  • Philippe Eigenmann
  • Benno Schnyder
  • Paul Whitacker
  • George Konstantinou
  • Cemal Cingi
  • Miguel Blanca
  • Javier Fernandez
  • Alexandra F Santos
  • Milena Sokolowska
  • Victoria Cardona
  • Isabel Skypala
  • Nicolette Dejong
  • Ulrike Raap
  • Paraskevi Xepapadaki
  • Claudio Rhyner
  • Lilit Hovhannisyan
  • Sven Seys
  • Kirsty Logan
  • Gunnar Nilsson
  • Gunter Sturm
  • Jean Luc Fauquert
  • Franziska Rueff
  • Jörg Kleine-Tebbe
  • Isabella Annesi-Maesano
  • Heidi Makrinioti
  • Berber Vlieg-Boerstra
  • Ervinç Mingomataj
  • Angel Mazon
  • James Gardner
  • Sevcan Celenk
  • Breda Flood
  • Liam O'Mahony
  • Francesco Annunziato
  • Antti Lauerma
  • Gianni Passalacqua
  • Beatrice M Bilò
  • Jeroen Buters
  • Pia Allegri
  • Gianenrico Senna
  • Roger Lauener
  • Christian Scharf

Detail Information

Publications14

  1. pmc Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria
    Claus Uhrenholt Christensen
    Allergy Center for West Denmark, Aarhus University Hospital, Aarhus, Denmark Department of Pulmonary Medicine, Aarhus University Hospital, Aarhus, Denmark
    Ann Dermatol 25:522-3. 2013
  2. pmc Research needs in allergy: an EAACI position paper, in collaboration with EFA
    Nikolaos G Papadopoulos
    Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
    Clin Transl Allergy 2:21. 2012
    ..Active involvement of all stakeholders, including Patient Organizations and policy makers are necessary to achieve the aims emphasized herein...
  3. doi request reprint Cultured human mast cells are heterogeneous for expression of the high-affinity IgE receptor FcεRI
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Aarhus University and Hospital, Aarhus, Denmark
    Int Arch Allergy Immunol 157:246-50. 2012
    ..We determined the density of FcεRI on mast cells cultured from cord (CBMC) and peripheral blood (PBMC) and studied the kinetics of the response through FcεRI...
  4. pmc Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapy
    Susan Mikkelsen
    Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Denmark
    Clin Mol Allergy 8:2. 2010
    ..Expression of CD203c was compared to CD63 as marker for basophil activation, using a Bland Altman plot and ROC curves...
  5. doi request reprint Human skin keratins are the major proteins in exhaled breath condensate
    H J Hoffmann
    Dept of Respiratory Diseases, Aarhus University Hospital, Denmark
    Eur Respir J 31:380-4. 2008
    ..Filtration of inspired air did not remove contaminating keratin. In conclusion, skin keratin in exhaled breath condensate derives from ambient air and not from the respiratory tract...
  6. doi request reprint Mast cell FcϵRI density and function dissociate from dependence on soluble IgE concentration at very low and very high IgE concentrations
    Inge Kortekaas Krohn
    Department of Respiratory Medicine, Aarhus University Hospital, Aarhus, Denmark
    J Asthma 50:117-21. 2013
    ..This study extends the dependence of effector cell degranulation on IgE concentration to mast cells cultured with IgE for 2 weeks...
  7. doi request reprint Comparison of short term in vitro cultured human mast cells from different progenitors - Peripheral blood-derived progenitors generate highly mature and functional mast cells
    Hanne Busk Andersen
    Department of Paediatrics, Aarhus University Hospital, DK 8200 Aarhus N, Denmark
    J Immunol Methods 336:166-74. 2008
    ..Cord and peripheral blood may give rise to different types of MC. The question addressed should determine the progenitor cell and protocol to be used...
  8. doi request reprint Seven week culture of functional human mast cells from buffy coat preparations
    Mette Holm
    Department of Human Genetics, University of Aarhus, DK 8000 Aarhus C, Denmark
    J Immunol Methods 336:213-21. 2008
    ..g. bone marrow or cord blood-derived progenitors. Consequently, our protocol has great potential in studies on mast cell biology and mast cell pathology, and e.g. on evaluation of drug effects...
  9. doi request reprint Pretreatment IgE sensitization patterns determine the molecular profile of the IgG4 response during updosing of subcutaneous immunotherapy with timothy grass pollen extract
    Johannes Martin Schmid
    Departments of Respiratory Medicine and Allergy, Aarhus University Hospital, Aarhus, Denmark
    J Allergy Clin Immunol 137:562-70. 2016
    ..Allergen immunotherapy is an effective treatment of allergic rhinoconjunctivitis. Clinical efficacy is associated with improvement of basophil sensitivity and an increase in allergen-specific immunoglobulin concentration...
  10. doi request reprint Asthmatics able to step down from inhaled corticosteroid treatment without loss of asthma control have low serum eotaxin/CCL11
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Arhus University Hospital, Denmark
    Clin Respir J 2:149-57. 2008
    ..The addition of a long-acting beta2 agonist (LABA) to inhaled corticosteroid (ICS) may control asthma better than ICS alone. Eosinophil markers may predict symptom severity in asthma...
  11. doi request reprint Determination of blood leukocyte concentration with constant volume acquisition on a flow cytometer is comparable to individualized single platform testing with beads as internal reference standard
    Susan Hansen
    Department of Respiratory Diseases, Aarhus University and Hospital, DK 8000 Aarhus C, Denmark
    J Immunol Methods 338:58-62. 2008
    ..CVA with PanLeukoGating can be established using microscopy as a reference, and is comparable to BT chamber and SPT determination. Leukocyte concentrations can be measured with CVA on flow cytometers in research and clinical settings...
  12. ncbi request reprint Response of respiratory flour allergics in an ingested flour challenge may involve plasmacytoid dendritic cells, CD25+ and CD152+ T cells
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Denmark
    Int Arch Allergy Immunol 140:252-60. 2006
    ..A number of occupational respiratory allergens are food related, and little is known about the responses these allergens elicit in sensitized persons that ingest them...
  13. ncbi request reprint A single exposure to organic dust of non-naïve non-exposed volunteers induces long-lasting symptoms of endotoxin tolerance
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Germany
    Int Arch Allergy Immunol 138:121-6. 2005
    ..Endotoxin tolerance has previously been described in vitro and animal studies as a mechanism that modifies the threshold at which response occurs...
  14. ncbi request reprint Psoriasin binds calcium and is upregulated by calcium to levels that resemble those observed in normal skin
    H J Hoffmann
    Institute of Medical Biochemistry, Aarhus University, Denmark
    J Invest Dermatol 103:370-5. 1994
    ..56) to levels that resemble those observed in unfractionated keratinocyte populations obtained from normal skin...