Research Topics
Genomes and GenesSpecies | Niels EhlersSummaryAffiliation: Aarhus University Hospital Country: Denmark Publications
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Detail Information
Publications
Altered expression of CLC, DSG3, EMP3, S100A2, and SLPI in corneal epithelium from keratoconus patientsKim Nielsen
Department of Ophthalmology, Aarhus University Hospital, Denmark
Cornea 24:661-8. 2005..This investigation was designed to determine whether the five genes, CLC, DSG3, EMP3, S100A2 and SLPI, are differentially expressed in keratoconus, as indicated from another study...
Riboflavin-ultraviolet light induced cross-linking in endothelial decompensationNiels Ehlers
Department of Ophthalmology, Arhus University Hospital, Arhus C, Denmark
Acta Ophthalmol 86:549-51. 2008..To evaluate the potential of collagen cross-linking in the treatment of corneal oedema caused by endothelial decompensation...
Phenotypic variability in Meesmann's dystrophy: clinical review of the literature and presentation of a family genetically identical to the original familyNiels Ehlers
Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
Acta Ophthalmol 86:40-4. 2008..To describe the phenotypic variability in Meesmann's microcystic dystrophy of the corneal epithelium based on a review of the literature and the presentation of a Danish family...
Riboflavin-UVA treatment in the management of edema and nonhealing ulcers of the corneaNiels Ehlers
Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
J Refract Surg 25:S803-6. 2009..The purpose of this study was to evaluate the potential of riboflavin-UVA treatment in the management of corneal disorders, in particular edema due to endothelial decompensation and non-healing ulcers...
Differences in the protein expression in limbal versus central human corneal epithelium--a search for stem cell markersMikkel Lyngholm
Department of Ophthalmology, Aarhus University Hospital, Norrebrogade 44, 8000 Aarhus C, Denmark
Exp Eye Res 87:96-105. 2008..SOD2 and CK15 identify clusters of limbal basal cells and therefore they may serve as markers for limbal stem cells in conjunction with the earliest transient amplifying cells...
Immunohistochemical markers for corneal stem cells in the early developing human eyeMikkel Lyngholm
Department of Ophthalmology, Aarhus University Hospital, Norrebrogade 44, 8000 Aarhus C, Denmark
Exp Eye Res 87:115-21. 2008..PAX6 was expressed in both ectodermally and mesodermally derived parts of the limbal niche, underscoring the importance of PAX6 in niche formation...
Alpha-1--antitrypsin in aqueous humour from patients with corneal allograft rejectionMikkel Funding
Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
Acta Ophthalmol Scand 83:379-84. 2005..To investigate the presence and concentration of alpha1-antitrypsin in aqueous humour at the time of corneal rejection and to compare results obtained from patients with reversible and irreversible rejection...
Re-examination of organ-cultured, cryopreserved human corneal grafts after 27 yearsCharlotte Corydon
Department of Ophthalmology, Arhus University Hospital, Denmark
Acta Ophthalmol 87:173-5. 2009..To determine the long-term fate of cryopreserved corneas. Review of 17 organ-cultered cryopreserved corneas grafted in 1978-1979...
Soluble CD163 and interleukin-6 are increased in aqueous humour from patients with endothelial rejection of corneal graftsMikkel Funding
Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
Acta Ophthalmol Scand 83:234-9. 2005....
Morphological evaluation of normal human corneal epitheliumNiels Ehlers
Department of Ophthalmology, University of Copenhagen, Denmark
Acta Ophthalmol 88:858-61. 2010..The purpose of this study is systemically to revisit the histopathological appearance of 100 corneas...
Attempting to distinguish between endogenous and contaminating cytokeratins in a corneal proteomic studyMikkel Lyngholm
Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
BMC Ophthalmol 11:3. 2011..This issue is especially important in proteomic studies of the corneal epithelium where several CK's have previously been reported to mark the stages of differentiation from corneal epithelial stem cell to the differentiated cell...
Corneal power, thickness, and stiffness: results of a prospective randomized controlled trial of PRK and LASIK for myopiaJesper Ø Hjortdal
Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
J Cataract Refract Surg 31:21-9. 2005....
Comparison of two partial coherence interferometers for corneal pachymetry in high myopia and after LASIKAnders Ivarsen
Department of Ophthalmology, Arhus University Hospital, Nørrebrogade 44, Arhus, Denmark
Acta Ophthalmol 87:392-5. 2009....
Descemet's stripping automated endothelial keratoplasty and penetrating keratoplasty for Fuchs' endothelial dystrophyJesper Hjortdal
Department of Ophthalmology, Aarhus University Hospital, Denmark
Acta Ophthalmol 87:310-4. 2009..To compare the outcome of Descemet's stripping endothelial keratoplasty (DSAEK) to that of penetrating keratoplasty (PK) in patients with Fuchs' endothelial dystrophy...
A novel mutation as the basis for asymptomatic meesmann dystrophy in a Danish familyKim Nielsen
Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
Cornea 27:100-2. 2008..Meesmann dystrophy is a rare inherited corneal disease. This is the description of a unique family in Denmark...
Simultaneous quantification of 17 immune mediators in aqueous humour from patients with corneal rejectionMikkel Funding
Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
Acta Ophthalmol Scand 84:759-65. 2006....
Corneal grafting and bankingNiels Ehlers
Danish Eye Bank, Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
Dev Ophthalmol 43:1-14. 2009..Developments in years to come may lead to control of graft biomechanics and optics. This technical development tends to favour a centralization...
Central corneal thickness in high myopiaLene Pedersen
Department of Ophthalmology, Aarhus University Hospital, Arhus Sygehus, Arhus, Denmark
Acta Ophthalmol Scand 83:539-42. 2005..To examine if central corneal thickness (CCT) is different in emmetropia and high myopia...
Proteome profiling of corneal epithelium and identification of marker proteins for keratoconus, a pilot studyKim Nielsen
Molecular Diagnostic Laboratory, Skejby Sygehus, Brendstrupgaarsvej, 8200 Aarhus N, Denmark
Exp Eye Res 82:201-9. 2006..Three proteins, gelsolin, alpha enolase, and S100A4 were identified to be differentially expressed in keratoconus compared to reference epithelium and thus may be involved in the pathogenesis...
Incidence and prevalence of keratoconus in DenmarkKim Nielsen
Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
Acta Ophthalmol Scand 85:890-2. 2007..To estimate the prevalence and incidence of hospitalized keratoconus (KC) in Denmark...
Proteomic analysis of aqueous humour from patients with acute corneal rejectionMikkel Funding
Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
Acta Ophthalmol Scand 83:31-9. 2005..To compare the basic proteomic composition of aqueous humour (AH) from patients with corneal rejection (patients) with AH from patients with cataract (controls)...
Are cataract and iris atrophy toxic complications of medical treatment of acanthamoeba keratitis?Niels Ehlers
Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
Acta Ophthalmol Scand 82:228-31. 2004..02% and propamidine isethionate 0.1%. It is suggested that these complications were caused by the chemicals, rather than resulting from the amoebae-induced inflammation...
Pupil size and night vision disturbances after LASIK for myopiaAndreas Helgesen
Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
Acta Ophthalmol Scand 82:454-60. 2004..We recommend preoperative evaluation of pupil size in all patients prior to LASIK surgery...
Precision and accuracy of the ICare tonometer - Peripheral and central IOP measurements by rebound tonometryDanson V Muttuvelu
Department of Ophthalmology, Aalborg Hospital Arhus University Hospital, Denmark
Acta Ophthalmol 90:322-6. 2012..The purpose of this study was to evaluate the ICare tonometers precision and accuracy and the extent to which intraocular pressure (IOP) measurements are influenced by measuring position...
Visual outcome, local tumour control, and eye preservation after 106Ru/Rh brachytherapy for choroidal melanomaPeter Isager
Department of Ophthalmology, Arhus University Hospital, Denmark
Acta Oncol 45:285-93. 2006..106Ru/Rh brachytherapy can be regarded as a good treatment option for small and medium-sized tumours but not for large tumours...
Corneal thickness: measurement and implicationsNiels Ehlers
Department of Ophthalmology, Arhus University Hospital, DK 8000 Arhus C, Denmark
Exp Eye Res 78:543-8. 2004..Finally it is discussed to what extent the thickness is a biometric parameter of significance, e.g. in the progression of myopia or in the development of retinal detachment...
Primary corneal myxomaLouise Hillerup Hansen
Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
Acta Ophthalmol Scand 82:224-7. 2004..The tumour was classified as a myxoma of the cornea. The origin of the tumour is discussed. CONCLUSION: This is the second reported case of a corneal myxoma without prior corneal disease...
Identification of differentially expressed genes in keratoconus epithelium analyzed on microarraysKim Nielsen
Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
Invest Ophthalmol Vis Sci 44:2466-76. 2003..Association between alterations at RNA and protein levels was observed for some of the tested candidates...
Corneal banking and grafting: the background to the Danish Eye Bank System, where corneas await their patientsNiels Ehlers
Department of Opthalmology, Arhus University Hospital, Denmark
Acta Ophthalmol Scand 80:572-8. 2002
Danish ophthalmology from 1950 to 1975Niels Ehlers
Dept of Ophthalmology, Arhus University Hospital, , DK-8000 Arhus C, Denmark
Acta Ophthalmol Scand Suppl 234:46-8. 2002
Brown corneaZita Steiber
Department of Ophthalmology, University of Debrecen, Debrecen, Hungary
Graefes Arch Clin Exp Ophthalmol 246:537-41. 2008..A brown cornea is relatively rare. We report a case of progressive brown corneal pigmentation in a patient with a primary acquired melanosis of the conjunctiva. Later the patient developed an iris melanoma...
[Excimer laser treatment of recurrent erosion of the cornea]Thomas Ege Nielsen
Arhus Universitetshospital, Arhus Sygehus, Ojenafdelingen
Ugeskr Laeger 167:1503-5. 2005
Histocompatibility and graftingNiels Ehlers
Acta Ophthalmol Scand 82:3-4. 2004
