T Bek

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. doi request reprint Relaxation of porcine retinal arterioles exposed to hypercholesterolemia in vivo is modified by hepatic LDL-receptor deficiency and diabetes mellitus
    Toke Bek
    Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, DK 8000 Aarhus C, Denmark Electronic address
    Exp Eye Res 115:79-86. 2013
  2. pmc Identification of differentially regulated proteins in a patient with Leber's Congenital Amaurosis--a proteomic study
    Henrik Vorum
    Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, DK 8000 Aarhus C, Denmark
    Proteome Sci 5:5. 2007
  3. doi request reprint Regional morphology and pathophysiology of retinal vascular disease
    Toke Bek
    Department of Ophthalmology, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Prog Retin Eye Res 36:247-59. 2013
  4. doi request reprint Spontaneous high frequency diameter oscillations of larger retinal arterioles are reduced in type 2 diabetes mellitus
    Toke Bek
    Department of Ophthalmology, Aarhus University Hospital, Denmark
    Invest Ophthalmol Vis Sci 54:636-40. 2013
  5. ncbi request reprint [Eye complications in type 2 diabetes mellitus]
    Toke Bek
    Øjenafdelingen, Aarhus Universitetshospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
    Ugeskr Laeger 174:2147-50. 2012
  6. doi request reprint GABA-induced relaxation of porcine retinal arterioles in vitro depends on inhibition from the perivascular retina and is mediated by GABAC receptors
    Toke Bek
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Invest Ophthalmol Vis Sci 53:3309-15. 2012
  7. doi request reprint Inner retinal ischaemia: current understanding and needs for further investigations
    Toke Bek
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Acta Ophthalmol 87:362-7. 2009
  8. doi request reprint The prevalence of diabetic retinopathy in patients with screen-detected type 2 diabetes in Denmark: the ADDITION study
    Toke Bek
    Department of Ophthalmology, Arhus University Hospital, Denmark
    Acta Ophthalmol 87:270-4. 2009
  9. doi request reprint Interaction between flicker-induced vasodilatation and pressure autoregulation in early retinopathy of type 2 diabetes
    Toke Bek
    Department of Ophthalmology, Arhus University Hospital, DK 8000 Arhus C, Denmark
    Graefes Arch Clin Exp Ophthalmol 246:763-9. 2008
  10. ncbi request reprint Diabetic retinopathy: a review of the aarhus approach to studies on epidemiology, computerised grading, and the pathophysiology of the disease
    T Bek
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Horm Metab Res 37:35-8. 2005

Detail Information

Publications61

  1. doi request reprint Relaxation of porcine retinal arterioles exposed to hypercholesterolemia in vivo is modified by hepatic LDL-receptor deficiency and diabetes mellitus
    Toke Bek
    Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, DK 8000 Aarhus C, Denmark Electronic address
    Exp Eye Res 115:79-86. 2013
    ..This suggests that transgenic animal models are suitable for studying the influence of systemic diseases on retinal vascular function. ..
  2. pmc Identification of differentially regulated proteins in a patient with Leber's Congenital Amaurosis--a proteomic study
    Henrik Vorum
    Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, DK 8000 Aarhus C, Denmark
    Proteome Sci 5:5. 2007
    ..The tissue was subjected to high resolution two-dimensional gel electrophoresis, image analysis and mass spectrometry, in an effort to identify differentially regulated proteins...
  3. doi request reprint Regional morphology and pathophysiology of retinal vascular disease
    Toke Bek
    Department of Ophthalmology, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Prog Retin Eye Res 36:247-59. 2013
    ..This may constitute the basis for future research in retinal vascular pathophysiology and for the development of new treatment modalities to reduce blindness secondary to retinal vascular disease. ..
  4. doi request reprint Spontaneous high frequency diameter oscillations of larger retinal arterioles are reduced in type 2 diabetes mellitus
    Toke Bek
    Department of Ophthalmology, Aarhus University Hospital, Denmark
    Invest Ophthalmol Vis Sci 54:636-40. 2013
    ..Therefore, the purpose of the present study was to characterize spontaneous oscillations in the diameter of retinal arterioles in normal persons and in persons with different severity of diabetic retinopathy...
  5. ncbi request reprint [Eye complications in type 2 diabetes mellitus]
    Toke Bek
    Øjenafdelingen, Aarhus Universitetshospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
    Ugeskr Laeger 174:2147-50. 2012
    ..However, recently intravitreal angiostatic therapy has been introduced as an effective new modality for the treatment of diabetic retinopathy...
  6. doi request reprint GABA-induced relaxation of porcine retinal arterioles in vitro depends on inhibition from the perivascular retina and is mediated by GABAC receptors
    Toke Bek
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Invest Ophthalmol Vis Sci 53:3309-15. 2012
    ....
  7. doi request reprint Inner retinal ischaemia: current understanding and needs for further investigations
    Toke Bek
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Acta Ophthalmol 87:362-7. 2009
    ..It is conceivable that a more detailed knowledge of these response patterns may help in the design of new treatments for retinal ischaemia and its vision-threatening consequences...
  8. doi request reprint The prevalence of diabetic retinopathy in patients with screen-detected type 2 diabetes in Denmark: the ADDITION study
    Toke Bek
    Department of Ophthalmology, Arhus University Hospital, Denmark
    Acta Ophthalmol 87:270-4. 2009
    ..This article reports the occurrence of diabetic retinopathy in this population...
  9. doi request reprint Interaction between flicker-induced vasodilatation and pressure autoregulation in early retinopathy of type 2 diabetes
    Toke Bek
    Department of Ophthalmology, Arhus University Hospital, DK 8000 Arhus C, Denmark
    Graefes Arch Clin Exp Ophthalmol 246:763-9. 2008
    ..In the present study we tested the working hypothesis that there is an interaction between these mechanisms that might be relevant for understanding and treating flow disturbances in diabetic retinopathy...
  10. ncbi request reprint Diabetic retinopathy: a review of the aarhus approach to studies on epidemiology, computerised grading, and the pathophysiology of the disease
    T Bek
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Horm Metab Res 37:35-8. 2005
    ..This review presents the scientific approach followed at Aarhus University Hospital in relation to three of these aspects-epidemiology, computerised grading, and elucidation of the pathophysiology of diabetic retinopathy...
  11. doi request reprint Lack of correlation between short-term dynamics of diabetic retinopathy lesions and the arterial blood pressure
    Toke Bek
    Department of Ophthalmology, Arhus University Hospital, DK 8000, Arhus C, Denmark
    Graefes Arch Clin Exp Ophthalmol 249:267-71. 2011
    ..However, a possible relationship between short-term fluctuations in diabetic retinopathy and risk factors for the long-term prognosis of diabetic retinopathy, such as the arterial blood pressure, has not been investigated...
  12. ncbi request reprint [Limited value of ophthalmoscopy in arterial hypertension]
    Toke Bek
    Øjenafdelingen, Aarhus Universitetshospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
    Ugeskr Laeger 173:2709-10. 2011
    ..However, this epidemiological tool has no predictive value for the individual patient. Hopefully, this paper may contribute to a limited number of superfluous referrals for ophthalmological examinations...
  13. ncbi request reprint Visual prognosis after panretinal photocoagulation for proliferative diabetic retinopathy
    Toke Bek
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Acta Ophthalmol Scand 84:16-20. 2006
    ..The visual acuity (VA) and grade of retinopathy before treatment are known indicators of the visual prognosis after treatment, but the prognostic value of other clinical background and treatment parameters is unknown...
  14. ncbi request reprint Endothelial dysfunction, ambulatory pulse pressure and albuminuria are associated in Type 2 diabetic subjects
    S T Knudsen
    Medical Department M Diabetes and Endocrinology, Aarhus University Hospital, Aarhus, Denmark
    Diabet Med 24:911-5. 2007
    ..The relation between endothelial dysfunction and PP in diabetic subjects has not previously been examined. We examined the relation between PP, markers of endothelial activation and albuminuria in Type 2 diabetic patients...
  15. doi request reprint Ambulatory pulse pressure, decreased nocturnal blood pressure reduction and progression of nephropathy in type 2 diabetic patients
    S T Knudsen
    Medical Department M Diabetes and Endocrinology, Aarhus University Hospital, Nørrebrogade 44, 8000, Aarhus C, Denmark
    Diabetologia 52:698-704. 2009
    ..We followed type 2 diabetic patients over a long period to evaluate the predictive value of ambulatory pulse pressure (PP) and decreased nocturnal BP reduction (non-dipping) for nephropathy progression...
  16. ncbi request reprint The blood pressure-induced diameter response of retinal arterioles decreases with increasing diabetic maculopathy
    Christian Alcaraz Frederiksen
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Graefes Arch Clin Exp Ophthalmol 244:1255-61. 2006
    ..The aim of the study was to compare the diameter response of retinal arterioles and retinal thickness in patients with different stages of diabetic maculopathy during an increase in the arterial blood pressure...
  17. pmc Impaired retinal autoregulation in small retinal arterioles before and after focal laser treatment for diabetic maculopathy
    P Jeppesen
    Department of Ophthalmology, Arhus University Hospital, Denmark
    Br J Ophthalmol 90:198-201. 2006
    ....
  18. ncbi request reprint The regional distribution of diabetic retinopathy lesions may reflect risk factors for progression of the disease
    T Bek
    Department of Ophthalmology, Arhus University Hospital, DK 8000 Arhus, Denmark
    Acta Ophthalmol Scand 79:501-5. 2001
    ..This grading method mainly considers the type and number of retinopathy lesions, implying that the diagnostic value of the regional distribution of retinopathy lesions is largely unknown...
  19. ncbi request reprint Short term visual prognosis after retinal laser photocoagulation for diabetic maculopathy
    T Bek
    Department of Ophthalmology, Arhus University Hospital, Denmark
    Acta Ophthalmol Scand 78:539-42. 2000
    ..Therefore, parameters are needed that can be used to ensure that treatment is modified or avoided in those patients who are at risk of experiencing visual loss...
  20. ncbi request reprint The prognostic value of post-treatment retinopathy after panretinal photocoagulation for proliferative diabetic retinopathy in type 1 diabetes
    T Bek
    Department of Ophthalmology, Arhus University Hospital, Arhus Denmark
    Eur J Ophthalmol 14:538-42. 2004
    ..However, no parameters are presently known that can be used to define an optimal control interval after the initial panretinal photocoagulation treatment that ensures enhancement of the treatment in cases where this is needed...
  21. ncbi request reprint Effects of losartan on diabetic maculopathy in type 2 diabetic patients: a randomized, double-masked study
    S T Knudsen
    Department of Medical M Diabetes and Endocrinology, Aarhus Kommunehospital, Aarhus, Denmark
    J Intern Med 254:147-58. 2003
    ..We evaluated the effect of treatment with the angiotensin II receptor antagonist losartan on macular oedema and hard exudates in patients with an advanced stage of DMa...
  22. ncbi request reprint Determination of free insulin-like growth factor-I in human serum: comparison of ultrafiltration and direct immunoradiometric assay
    J Frystyk
    Institute of Experimental Clinical Research and Medical Department M, Aarhus University Hospital, Denmark
    Growth Horm IGF Res 11:117-27. 2001
    ..IRMA was less affected than UF by added IGFBP-1 and -2, and reductions in free IGF-I were better revealed by UF than IRMA...
  23. ncbi request reprint Plasma concentrations of osteoprotegerin during normo- and hyperglycaemic clamping
    S T Knudsen
    Medical Department M Diabetes and Endocrinology, Aarhus University Hospital, Aarhus, Denmark
    Scand J Clin Lab Invest 67:135-42. 2007
    ..The aim of the present study was to examine the effect of acute hyperglycaemia on plasma levels of OPG in non-diabetic subjects...
  24. ncbi request reprint Increased blood pressure induces a diameter response of retinal arterioles that increases with decreasing arteriolar diameter
    Peter Jeppesen
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Invest Ophthalmol Vis Sci 48:328-31. 2007
    ..To study the diameter response of retinal arterioles as a function of the arteriolar diameter...
  25. ncbi request reprint The age-dependent decrease in the myogenic response of retinal arterioles as studied with the Retinal Vessel Analyzer
    Peter Jeppesen
    Department of Ophthalmology, Arhus University Hospital, Nørrebrogade 44, 8000, Arhus C, Denmark
    Graefes Arch Clin Exp Ophthalmol 242:914-9. 2004
    ..To study the age-dependent change in myogenic response of retinal arterioles...
  26. ncbi request reprint The prevalence of retinopathy in an unselected population of type 2 diabetes patients from Arhus County, Denmark
    Marianne N Hove
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Acta Ophthalmol Scand 82:443-8. 2004
    ..To determine the prevalence of diabetic retinopathy and the causes of visual impairment in an unselected population of type 2 diabetes patients, and to describe the risk factors for developing diabetic retinopathy in this population...
  27. ncbi request reprint A clinicopathological study of venous loops and reduplications in diabetic retinopathy
    Toke Bek
    Department of Ophthalmology, Arhus University Hospital, Denmark
    Acta Ophthalmol Scand 80:69-75. 2002
    ..To study possible causes of the gradual venous occlusion that precedes the formation of venous loops and reduplications in diabetic retinopathy using histopathological techniques...
  28. ncbi request reprint Quantitative analysis of retinopathy in type 2 diabetes: identification of prognostic parameters for developing visual loss secondary to diabetic maculopathy
    M N Hove
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Acta Ophthalmol Scand 82:679-85. 2004
    ..To describe whether quantitative assessment of early changes in the morphology of retinopathy lesions can predict development of vision-threatening diabetic maculopathy...
  29. ncbi request reprint E-selectin-inducing activity in plasma from type 2 diabetic patients with maculopathy
    S T Knudsen
    Medical Department M Diabetes and Endocrinology, Institute of Pathology, Aarhus University Hospital, Denmark
    Am J Physiol Endocrinol Metab 284:E1-6. 2003
    ..Enhanced expression of E-selectin may contribute to the development of DMa in type 2 diabetes...
  30. ncbi request reprint Quantitative anomaloscopy and optical coherence tomography scanning in central serous chorioretinopathy
    T Bek
    Department of Ophthalmology, Arhus University Hospital, Denmark
    Acta Ophthalmol Scand 78:632-7. 2000
    ..The relative contribution from the two causes is unknown, but may be elucidated by obtaining knowledge of the anatomical derangement in the diseased retina in CSC...
  31. ncbi request reprint ATP-induced relaxation of porcine retinal arterioles depends on the perivascular retinal tissue and acts via an adenosine receptor
    Kim Holmgaard
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Curr Eye Res 32:353-9. 2007
    ..Purinergic compounds and cyclooxygenase inhibitors are involved in the tone regulation of isolated retinal arterioles in vitro, but it is unknown whether the perivascular retinal tissue influences these effects...
  32. ncbi request reprint Response of retinal arteriole diameter to increased blood pressure during acute hyperglycaemia
    Peter Jeppesen
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Acta Ophthalmol Scand 85:280-6. 2007
    ..To study retinal response in terms of arteriole diameter and retinal thickness secondary to an increase in arterial blood pressure during acute hyperglycaemia...
  33. ncbi request reprint The relaxing effect of perivascular tissue on porcine retinal arterioles in vitro is mimicked by N-methyl-D-aspartate and is blocked by prostaglandin synthesis inhibition
    Kim Holmgaard
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Acta Ophthalmol 86:26-33. 2008
    ..The purpose of the present study was to test whether N-methyl-D-aspartate (NMDA) and gamma-amino butyric acid (GABA) receptors, and a cyclooxygenase (COX) product influence this effect of perivascular retinal tissue in vitro...
  34. ncbi request reprint The relationships between risk factors and the distribution of retinopathy lesions in type 2 diabetes
    Marianne Nørgård Hove
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Acta Ophthalmol Scand 84:619-23. 2006
    ..The purpose of the present study was to examine whether the occurrence of retinopathy in these retinal areas is related to known risk factors for progression of retinopathy in type 2 diabetes...
  35. ncbi request reprint Bradykinin relaxation in small porcine retinal arterioles
    Peter Jeppesen
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Invest Ophthalmol Vis Sci 43:1891-6. 2002
    ....
  36. ncbi request reprint Increased serum IGF-I during pregnancy is associated with progression of diabetic retinopathy
    Finn F Lauszus
    Department of Obstetrics Gynecology, Skejby Hospital, Aarhus University Hospital, Aarhus, Denmark
    Diabetes 52:852-6. 2003
    ..01). During pregnancy, serum IGF-I increased with increasing birth weight until a plateau was reached in week 32. Birth weight was significantly associated with a higher level of serum IGF-I (P < 0.01)...
  37. ncbi request reprint The occurrence and causes of registered blindness in diabetes patients in Arhus County, Denmark
    Peter Jeppesen
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Acta Ophthalmol Scand 82:526-30. 2004
    ..To report the occurrence of registered blindness among diabetes patients in Arhus County, Denmark during 1993-2002...
  38. ncbi request reprint The relationship between the circulating IGF system and the presence of retinopathy in Type 1 diabetic patients
    J Frystyk
    Medical Research Laboratories, Institute of Experimental Clinical Research, Aarhus University Hospital, Aarhus, Denmark
    Diabet Med 20:269-76. 2003
    ..To date, interest has focused on the role of circulating total IGF-I in the development of PDR, and there are only sparse data on circulating levels of free IGF-I and IGFBPs...
  39. ncbi request reprint Markers of thrombophilia in retinal vein thrombosis
    L Hansen
    The Department of Ophthalmology, University Hospital Aarhus Skejby, Aarhus, Denmark
    Acta Ophthalmol Scand 78:523-6. 2000
    ..To study the prevalence of risk factors for systemic thromboembolism in patients with retinal vein thrombosis (RVT)...
  40. ncbi request reprint The relation between visual acuity, fixation stability, and the size and location of foveal hard exudates after photocoagulation for diabetic maculopathy: a 1-year follow-up study
    F Møller
    Department of Ophthalmology, Odense University Hospital, 5000, Odense C, Denmark
    Graefes Arch Clin Exp Ophthalmol 241:458-62. 2003
    ..To study the relation between changes in visual acuity, fixation stability and the retinal area covered by hard exudates 3, 6 and 12 months after laser photocoagulation for diabetic maculopathy...
  41. ncbi request reprint Pulse pressure and diurnal blood pressure variation: association with micro- and macrovascular complications in type 2 diabetes
    Søren Tang Knudsen
    Medical Department M Diabetes and Endocrinology, Aarhus Kommunehospital, Aarhus, Denmark
    Am J Hypertens 15:244-50. 2002
    ..We investigated the association between retinopathy, nephropathy, macrovascular disease, PP, and diurnal BP variation in a group of type 2 diabetic patients...
  42. doi request reprint The vasodilating effect of acetazolamide and dorzolamide involves mechanisms other than carbonic anhydrase inhibition
    Maria Skytte Torring
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Invest Ophthalmol Vis Sci 50:345-51. 2009
    ..The purpose of the present study was to investigate whether CO(2), H(+), or factors other than carbonic anhydrase inhibition are involved in this vasodilating effect...
  43. doi request reprint ATP-induced relaxation of porcine retinal arterioles in vitro depends on prostaglandin E synthesized in the perivascular retinal tissue
    Kim Holmgaard
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Invest Ophthalmol Vis Sci 51:5168-75. 2010
    ..The purpose of the present study was to identify the prostaglandins involved in this retina-dependent relaxation...
  44. ncbi request reprint Adenosine relaxation in small retinal arterioles requires functional Na-K pumps and K(ATP) channels
    Peter Jeppesen
    Dept of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Curr Eye Res 25:23-8. 2002
    ..To study the effect of Na-K pump and K(ATP) channel inhibition on the diameter and the adenosine-induced vasodilation of small retinal arterioles...
  45. ncbi request reprint Effect of acidosis on isolated porcine retinal vessels
    Anders Hessellund
    Department of Ophthalmology, Aarhus University Hospital, 8000 Aarhus C, Denmark
    Curr Eye Res 31:427-34. 2006
    ..To study the effect of normocapnic (NA) and hypercapnic acidosis (HA) on the tone, the intracellular calcium level ([Ca(2 +)](i)), and the membrane potential of smooth muscle cells in porcine retinal arterioles...
  46. doi request reprint N-methyl-D-aspartic acid causes relaxation of porcine retinal arterioles through an adenosine receptor-dependent mechanism
    Kim Holmgaard
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Invest Ophthalmol Vis Sci 49:4590-4. 2008
    ..However, it remains to be elucidated whether the relaxing action of the two substances are coupled...
  47. ncbi request reprint Effect of cyclic guanosine-monophosphate on porcine retinal vasomotion
    Anders Hessellund
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Acta Ophthalmol Scand 84:228-33. 2006
    ..Previous evidence from vessels outside the eye suggests that cyclic guanosine-monophosphate (cGMP) is involved in the regulation of vasomotion, but it is unknown whether this compound has an effect on vasomotion in retinal vessels...
  48. ncbi request reprint Variable involvement of the perivascular retinal tissue in carbonic anhydrase inhibitor induced relaxation of porcine retinal arterioles in vitro
    Anne Katrine Kehler
    Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
    Invest Ophthalmol Vis Sci 48:4688-93. 2007
    ..However, the exact nature of this interplay is unknown...
  49. pmc Ocular changes in heredo-oto-ophthalmo-encephalopathy
    T Bek
    Department of Ophthalmology, Arhus University Hospital, DK 8000 Arhus C, Denmark
    Br J Ophthalmol 84:1298-302. 2000
    ..Currently, no detailed description has been given of the ocular changes seen in HOOE. Therefore, the ocular changes of HOOE were described on the basis of clinical and histological data from six affected family members...
  50. pmc Clinical pathology and retinal vascular structure in the Bardet-Biedl syndrome
    T Bek
    Department of Ophthalmology, Arhus University Hospital, Denmark
    Br J Ophthalmol 79:76-80. 1995
    ..The findings are discussed in relation to possible pathophysiological mechanisms involved in the development of retinal dystrophy in the Bardet-Biedl syndrome...
  51. ncbi request reprint Characterization of vasomotion in porcine retinal arterioles
    Anders Hessellund
    Department of Ophthalmology, Arhus University Hospital, Denmark
    Acta Ophthalmol Scand 81:278-82. 2003
    ..To characterize vasomotion in porcine retinal arterioles in vitro using isobaric (pressure myograph) and isometric (wire myograph) methods...
  52. doi request reprint Voltage-gated calcium channels are involved in the regulation of calcium oscillations in vascular smooth muscle cells from isolated porcine retinal arterioles
    Mikkel Wölck Misfeldt
    Aarhus University Hospital, Department of Ophthalmology, Norrebrogade 44, 8000 Aarhus C, Denmark
    Exp Eye Res 91:69-75. 2010
    ..However, both sites of calcium recruitment seem to have unique properties in porcine retinal arterioles as compared to other organs...
  53. ncbi request reprint Myogenic response in isolated porcine retinal arterioles
    Peter Jeppesen
    Department of Ophthalmology, Arhus University Hospital, Denmark
    Curr Eye Res 27:217-22. 2003
    ..To study the myogenic response in large and small porcine retinal arterioles and the effects of blockade of L-type voltage gated calcium channels on the myogenic response...
  54. doi request reprint Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial
    Anne Katrin Sjølie
    Department of Ophthalmology, Odense University Hospital, Odense, Denmark
    Lancet 372:1385-93. 2008
    ..Diabetic retinopathy remains a leading cause of visual loss in people of working age. We examined whether candesartan treatment could slow the progression and, secondly, induce regression of retinopathy in people with type 2 diabetes...
  55. ncbi request reprint Macular edema reflects generalized vascular hyperpermeability in type 2 diabetic patients with retinopathy
    Søren T Knudsen
    Medical Department M Diabetes and Endocrinology, Aarhus Kommunehospital, Denmark
    Diabetes Care 25:2328-34. 2002
    ....
  56. ncbi request reprint The relationship between age and colour content in fundus images
    Bernhard M Ege
    Department of Medical Informatics and Imaging, Institute for Electronic Systems, Aalborg University, Denmark
    Acta Ophthalmol Scand 80:485-9. 2002
    ..The introduction of a method for quantifying this age-related change in colour content may help in diagnosing and grading pathological changes in the eye lens which are secondary to ocular and systemic diseases...
  57. ncbi request reprint TOSCA-Imaging--developing Internet based image processing software for screening and diagnosis of diabetic retinopathy
    Ole Hejlesen
    Department of Health Science and Technology, Aalborg University, Fredrik Bajersvej 7D1, DK 9220 Aalborg, Denmark
    Stud Health Technol Inform 107:222-6. 2004
    ....
  58. ncbi request reprint Using a model of the colour content in retinal fundus images to screen for sight threatening diabetic retinopathy
    Bernhard M Ege
    Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7D, 9220 Aalborg, Denmark
    Stud Health Technol Inform 90:18-23. 2002
    ....
  59. doi request reprint Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials
    Nish Chaturvedi
    International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College Healthcare NHS Trust, London, UK
    Lancet 372:1394-402. 2008
    ..We therefore designed the DIabetic REtinopathy Candesartan Trials (DIRECT) Programme to assess whether candesartan could reduce the incidence and progression of retinopathy in type 1 diabetes...
  60. ncbi request reprint [Diagnostic value of the chromatic contents of fundus photography]
    Toke Bek
    Ojenafdelingen, Arhus Kommunehospital, Arhus Universitetshospital, 8000 Arhus
    Ugeskr Laeger 165:2561-2. 2003
    ..The method is another example of the eye as a significant viewer to the study of generalized diseases and their systemic complications...
  61. ncbi request reprint Thyroid-associated orbitopathy (TAO) treated by lateral orbital decompression
    Dorte Ancher Larsen
    Acta Ophthalmol Scand 82:108-9. 2004