P Laurberg

Summary

Affiliation: Aalborg Hospital
Country: Denmark

Publications

  1. ncbi request reprint Iodine nutrition in breast-fed infants is impaired by maternal smoking
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 89:181-7. 2004
  2. ncbi request reprint Global or Gaelic epidemic of hypothyroidism?
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Lancet 365:738-40. 2005
  3. ncbi request reprint Hypothyroidism in the elderly: pathophysiology, diagnosis and treatment
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Drugs Aging 22:23-38. 2005
  4. ncbi request reprint Remission of Graves' disease during anti-thyroid drug therapy. Time to reconsider the mechanism?
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 155:783-6. 2006
  5. ncbi request reprint Evaluating iodine deficiency in pregnant women and young infants-complex physiology with a risk of misinterpretation
    P Laurberg
    Department of Endocrinology, Aalborg Hospital, Aalborg, Denmark
    Public Health Nutr 10:1547-52; discussion 1553. 2007
  6. ncbi request reprint Cold adaptation and thyroid hormone metabolism
    P Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Horm Metab Res 37:545-9. 2005
  7. ncbi request reprint Thiocyanate in food and iodine in milk: from domestic animal feeding to improved understanding of cretinism
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aalborg, Denmark
    Thyroid 12:897-902. 2002
  8. ncbi request reprint Humic substances in drinking water and the epidemiology of thyroid disease
    Peter Laurberg
    Department of Endocrinology and Medicine, University Hospital Aalborg, Denmark
    Biofactors 19:145-53. 2003
  9. ncbi request reprint The Danish investigation on iodine intake and thyroid disease, DanThyr: status and perspectives
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 155:219-28. 2006
  10. ncbi request reprint Environmental iodine intake affects the type of nonmalignant thyroid disease
    P Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Denmark
    Thyroid 11:457-69. 2001

Collaborators

Detail Information

Publications82

  1. ncbi request reprint Iodine nutrition in breast-fed infants is impaired by maternal smoking
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 89:181-7. 2004
    ..Smoking during the period of breastfeeding increases the risk of iodine deficiency-induced brain damage in the child. Women who breastfeed should not smoke, but if they do, an extra iodine supplement should be considered...
  2. ncbi request reprint Global or Gaelic epidemic of hypothyroidism?
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Lancet 365:738-40. 2005
  3. ncbi request reprint Hypothyroidism in the elderly: pathophysiology, diagnosis and treatment
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Drugs Aging 22:23-38. 2005
    ..In elderly patients on replacement therapy, care should include estimation of serum TSH level once or twice a year, with small dosage adjustments of levothyroxine sodium to keep serum TSH level within the normal range...
  4. ncbi request reprint Remission of Graves' disease during anti-thyroid drug therapy. Time to reconsider the mechanism?
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 155:783-6. 2006
    ..The conclusion that remission is associated with restoration of the euthyroid state, and that it is not a special drug effect, highlights the importance of making and keeping patients with Graves' disease euthyroid...
  5. ncbi request reprint Evaluating iodine deficiency in pregnant women and young infants-complex physiology with a risk of misinterpretation
    P Laurberg
    Department of Endocrinology, Aalborg Hospital, Aalborg, Denmark
    Public Health Nutr 10:1547-52; discussion 1553. 2007
    ..To review methods for evaluating iodine deficiency in pregnant women and young infants and to discuss factors to be considered in the interpretation of their results...
  6. ncbi request reprint Cold adaptation and thyroid hormone metabolism
    P Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Horm Metab Res 37:545-9. 2005
    ..Another hypothetical possibility is recruitment of brown adipocytes embedded in white adipose tissue in human adults. Understanding cold adaptation in human adults may lead to development of new drugs against obesity...
  7. ncbi request reprint Thiocyanate in food and iodine in milk: from domestic animal feeding to improved understanding of cretinism
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aalborg, Denmark
    Thyroid 12:897-902. 2002
    ..It can be speculated that a low-iodine content of mother's milk because of inhibition of NIS in the mammary gland may be one factor of importance for development of myxedematous cretinism...
  8. ncbi request reprint Humic substances in drinking water and the epidemiology of thyroid disease
    Peter Laurberg
    Department of Endocrinology and Medicine, University Hospital Aalborg, Denmark
    Biofactors 19:145-53. 2003
    ..The effect of humic substances in drinking water on the epidemiology of thyroid disease probably depends on the source of aquifer sediments...
  9. ncbi request reprint The Danish investigation on iodine intake and thyroid disease, DanThyr: status and perspectives
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 155:219-28. 2006
    ..p.m. iodine) was initiated in 2000/2001. The Danish investigation on iodine intake and thyroid disease (DanThyr) is the monitoring of the iodine fortification program...
  10. ncbi request reprint Environmental iodine intake affects the type of nonmalignant thyroid disease
    P Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Denmark
    Thyroid 11:457-69. 2001
    ....
  11. ncbi request reprint Thyroid disorders in mild iodine deficiency
    P Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Denmark
    Thyroid 10:951-63. 2000
    ..Iodine supplementation programs should aim at relatively uniform iodine intake, avoiding deficient or excessive iodine intake in subpopulations. To adopt such a strategy, surveillance programs are needed...
  12. ncbi request reprint Acute presentation of craniopharyngioma in children and adults in a Danish national cohort
    E H Nielsen
    Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, 9000, Aalborg, Denmark
    Pituitary 16:528-35. 2013
    ..Craniopharyngioma presented with acute symptoms in 13% of patients. Childhood onset and radiologic signs of calcification were independent risk factors for acute presentation. Intra-tumour haemorrhage was rare...
  13. ncbi request reprint Variations in urinary iodine excretion and thyroid function. A 1-year study in healthy men
    S Andersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Reberbansgade, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 144:461-5. 2001
    ..g. 25 microg/l, may suggest iodine deficiency in part of the population. However, urinary iodine varies considerably from day to day and the fraction of low samples caused by dispersion remains unsettled...
  14. doi request reprint Assays for thyroid-stimulating hormone receptor antibodies employing different ligands and ligand partners may have similar sensitivity and specificity but are not interchangeable
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aarhus University Hospital, Aalborg, Denmark
    Thyroid 20:127-33. 2010
    ..In the "bTSH-rhTSHR" assay, hTSHR-Ab competes with labeled bovine TSH for binding to recombinant human TSH receptors...
  15. ncbi request reprint Epidemiology of subtypes of hypothyroidism in Denmark
    Allan Carlé
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 154:21-8. 2006
    ..We therefore studied incidences of subtypes of primary, overt hypothyroidism in a Danish population cohort and compared incidences in two subcohorts with different levels of iodine intake...
  16. doi request reprint Serum TSH and serum thyroid peroxidase antibody fluctuate in parallel and high urinary iodine excretion predicts subsequent thyroid failure in a 1-year study of patients with untreated subclinical hypothyroidism
    Jesper Karmisholt
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, 9000 Aalborg, Denmark
    Eur J Endocrinol 158:209-15. 2008
    ....
  17. ncbi request reprint Postpartum thyroid dysfunction in pregnant thyroid peroxidase antibody-positive women living in an area with mild to moderate iodine deficiency: is iodine supplementation safe?
    S B Nøhr
    Department of Obstetrics and Gynecology, Aalborg Hospital, Denmark
    J Clin Endocrinol Metab 85:3191-8. 2000
    ..The study confirmed that screening for TPO-Ab in early pregnancy can predict women at high risk for development of PPTD...
  18. ncbi request reprint An increased incidence of overt hypothyroidism after iodine fortification of salt in Denmark: a prospective population study
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 92:3122-7. 2007
    ..We prospectively identified all new cases of overt hypothyroidism in two areas of Denmark before and for the first 7 yr after IF had been introduced...
  19. ncbi request reprint Smoking as a risk factor for Graves' disease, toxic nodular goiter, and autoimmune hypothyroidism
    Peter Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Denmark
    Thyroid 12:69-75. 2002
    ..In conclusion, smoking is a powerful risk factor for thyroid disease, especially in populations with a high smoking frequency. Oral contraceptive use is associated with a slightly lower frequency of Graves' disease...
  20. ncbi request reprint Thyroid volume in hypothyroidism due to autoimmune disease follows a unimodal distribution: evidence against primary thyroid atrophy and autoimmune thyroiditis being distinct diseases
    Allan Carlé
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 94:833-9. 2009
    ..Primary overt autoimmune hypothyroidism is often divided into primary idiopathic hypothyroidism with thyroid atrophy (Ord's disease) and hypothyroidism with goitre (Hashimoto's disease)...
  21. ncbi request reprint TSH-receptor antibody measurement for differentiation of hyperthyroidism into Graves' disease and multinodular toxic goitre: a comparison of two competitive binding assays
    I B Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aalborg, Denmark
    Clin Endocrinol (Oxf) 55:381-90. 2001
    ..Furthermore, to evaluate the applicability of the H-TRAb assay to discriminate between patients with hyperthyroidism due to Graves' disease (GD) and multinodular toxic goitre (MNTG)...
  22. ncbi request reprint Analytical goals for thyroid function tests when monitoring patients with untreated subclinical hypothyroidism
    Jesper Karmisholt
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Scand J Clin Lab Invest 70:264-8. 2010
    ....
  23. ncbi request reprint Variation in thyroid function tests in patients with stable untreated subclinical hypothyroidism
    Jesper Karmisholt
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Thyroid 18:303-8. 2008
    ..We aimed to describe intra-individual variation in thyroid function in patients with stable, untreated subclinical hypothyroidism (SCH) compared to euthyroid individuals to assess the importance of monitoring SCH patients...
  24. ncbi request reprint Sources of circulating 3,5,3'-triiodothyronine in hyperthyroidism estimated after blocking of type 1 and type 2 iodothyronine deiodinases
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    J Clin Endocrinol Metab 92:2149-56. 2007
    ..Graves' hyperthyroidism and multinodular toxic goiter lead to high serum T(3) compared with serum T(4). The source of this high T(3) has not been clarified...
  25. doi request reprint Hypothyroidism secondary to hypothalamic-pituitary dysfunction may be part of the phenotype in klinefelter syndrome: a case-control study
    Anne Mette Bay Bjørn
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 94:2478-81. 2009
    ..Klinefelter syndrome (KS) may involve a number of abnormalities besides the characteristic testicular insufficiency. Some studies have suggested that thyroid abnormalities may be common, but this has not been clarified...
  26. ncbi request reprint Changes in iodine excretion in 50-69-y-old denizens of an Arctic society in transition and iodine excretion as a biomarker of the frequency of consumption of traditional Inuit foods
    Stig Andersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Denmark
    Am J Clin Nutr 81:656-63. 2005
    ..Iodine intake in Greenland has been hypothesized to exceed 10 times the recommended amount. The transition from a traditional Arctic society may change the iodine intake, but no field studies have been performed...
  27. doi request reprint TSH-receptor autoimmunity in Graves' disease after therapy with anti-thyroid drugs, surgery, or radioiodine: a 5-year prospective randomized study
    Peter Laurberg
    Department of Endocrinology and Internal Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 158:69-75. 2008
    ..Autoimmunity against the TSH receptor is a key pathogenic element in Graves' disease. The autoimmune aberration may be modified by therapy of the hyperthyroidism...
  28. ncbi request reprint Frequent occurrence of pituitary apoplexy in patients with non-functioning pituitary adenoma
    E Husted Nielsen
    Department of Endocrinology, Aarhus University Hospital, Aalborg, Denmark
    Clin Endocrinol (Oxf) 64:319-22. 2006
    ..There is agreement in the literature that pituitary apoplexy is a rare disorder. As our experience differs from this view, we analysed the incidence in patients operated on for a nonfunctioning pituitary adenoma...
  29. ncbi request reprint Increase in incidence of hyperthyroidism predominantly occurs in young people after iodine fortification of salt in Denmark
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 91:3830-4. 2006
    ..We prospectively registered all new cases of overt hyperthyroidism in two areas of Denmark before and for the first 6 yr after iodine fortification...
  30. ncbi request reprint Lack of association between thyroid autoantibodies and parity in a population study argues against microchimerism as a trigger of thyroid autoimmunity
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 154:39-45. 2006
    ..It has also been suggested that foetal microchimerism involving transfer of foetal cells into maternal tissue during pregnancy may play an important role...
  31. ncbi request reprint More hypothyroidism and less hyperthyroidism with sufficient iodine nutrition compared to mild iodine deficiency--a comparative population-based study of older people
    Stig Andersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Hobrovej 18 22, 9000 Aalborg, Denmark
    Maturitas 64:126-31. 2009
    ..To assess the occurrence of thyroid disorders and autoimmunity in a geriatric population with long-standing recommended iodine intake of natural origin compared to mild iodine deficiency...
  32. ncbi request reprint Narrow individual variations in serum T(4) and T(3) in normal subjects: a clue to the understanding of subclinical thyroid disease
    Stig Andersen
    Department of Endocrinology, Aalborg Hospital, Aalborg, Denmark DK 9000
    J Clin Endocrinol Metab 87:1068-72. 2002
    ..For the same degree of thyroid function abnormality, the diagnosis depends to a considerable extent on the position of the patient's normal set point for T(4) and T(3) within the laboratory reference range...
  33. ncbi request reprint Smoking is negatively associated with the presence of thyroglobulin autoantibody and to a lesser degree with thyroid peroxidase autoantibody in serum: a population study
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Eur J Endocrinol 158:367-73. 2008
    ..The knowledge of a possible association between lifestyle factors and circulating thyroid antibodies is limited...
  34. ncbi request reprint Large differences in incidences of overt hyper- and hypothyroidism associated with a small difference in iodine intake: a prospective comparative register-based population survey
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, DK 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 87:4462-9. 2002
    ..The optimal level of iodine intake to prevent thyroid disease may be a relatively narrow range around the recommended daily iodine intake of 150 micro g...
  35. ncbi request reprint Surveyance of disease frequency in a population by linkage to diagnostic laboratory databases. A system for monitoring the incidences of hyper- and hypothyroidism as part of the Danish iodine supplementation program
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Reberbansgade, DK 9000 Aalborg, Denmark
    Comput Methods Programs Biomed 67:209-16. 2002
    ..In Denmark an increase in iodine intake through salt iodization has been introduced in 1998. In parallel a program for surveyance of thyroid diseases in the population was developed as recommended by UNICEF and WHO...
  36. ncbi request reprint Thyroid peroxidase and thyroglobulin autoantibodies in a large survey of populations with mild and moderate iodine deficiency
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Denmark
    Clin Endocrinol (Oxf) 58:36-42. 2003
    ..In the present study we evaluated if TPO-Ab and Tg-Ab tend to develop in parallel or whether one or the other may be more prevalent in subsets of the population...
  37. ncbi request reprint Thyroid peroxidase and thyroglobulin auto-antibodies in patients with newly diagnosed overt hypothyroidism
    Allan Carlé
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Autoimmunity 39:497-503. 2006
    ..Thyroid autoimmunity is a major cause for hypothyroidism. We describe thyroid auto-antibodies in patients with various nosological subtypes of hypothyroidism identified in a population study...
  38. ncbi request reprint A population study of the association between thyroid autoantibodies in serum and abnormalities in thyroid function and structure
    Inge Bülow Pedersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Denmark
    Clin Endocrinol (Oxf) 62:713-20. 2005
    ..The aims of this study were to evaluate the association between thyroid autoantibodies in serum and abnormalities in thyroid function and structure, and to study the thyroid volume in subjects with subclinical autoimmune hypothyroidism...
  39. ncbi request reprint Differences in reproducibility and peak growth hormone responses to repeated testing with various stimulators in healthy adults
    H C Hoeck
    Department of Medicine and Endocrinology, Aalborg Hospital, Denmark
    Growth Horm IGF Res 9:18-24. 1999
    ..Test results in patients should be evaluated against test-specific reference values, and caution is justified in the interpretation of low responses in a single test...
  40. ncbi request reprint Interval between tests and thyroxine estimation method influence outcome of monitoring of subclinical hypothyroidism
    Jesper Karmisholt
    Department of Medical Endocrinology, Aalborg Hospital, Aarhus University Hospital, 9000 Aalborg, Denmark
    J Clin Endocrinol Metab 93:1634-40. 2008
    ....
  41. ncbi request reprint Mortality and GH deficiency: a nationwide study
    Kirstine Stochholm
    Medical Department M Endocrinology and Diabetes, Aarhus University Hospital, Aarhus Sygehus, NBG, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 157:9-18. 2007
    ..To estimate the mortality in Denmark in patients suffering from GH deficiency (GHD)...
  42. ncbi request reprint Age modifies the pituitary TSH response to thyroid failure
    Allan Carlé
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Denmark
    Thyroid 17:139-44. 2007
    ..To investigate the association between serum TSH, total T4 and various patient characteristics when hypothyroidism is diagnosed in a population, and to study how age, sex and serum T4 levels influenced pituitary TSH response...
  43. doi request reprint Speciation of iodine in high iodine groundwater in china associated with goitre and hypothyroidism
    Stig Andersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Arhus University Hospital, Aalborg, Denmark
    Biol Trace Elem Res 128:95-103. 2009
    ..High iodine intake from iodine-rich water suggests the cause of endemic goitre and hypothyroidism in some areas in China being iodine...
  44. ncbi request reprint Iodine intake as a determinant of thyroid disorders in populations
    Peter Laurberg
    Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, DK 9000 Aalborg, Denmark
    Best Pract Res Clin Endocrinol Metab 24:13-27. 2010
    ....
  45. doi request reprint Intake of traditional Inuit diet vary in parallel with inflammation as estimated from YKL-40 and hsCRP in Inuit and non-Inuit in Greenland
    L H Schæbel
    Arctic Health Research Centre, Aalborg University Hospital, Aalborg, Denmark
    Atherosclerosis 228:496-501. 2013
    ..This was rare in pre-western Inuit who lived on a diet that consisted mainly of marine mammals rich in n-3 fatty acids...
  46. doi request reprint Incidence of craniopharyngioma in Denmark (n = 189) and estimated world incidence of craniopharyngioma in children and adults
    E H Nielsen
    Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, 9000, Aalborg, Denmark
    J Neurooncol 104:755-63. 2011
    ..Overall IR of craniopharyngioma in Denmark was 1.86 (1.60-2.14) as compared to 2.14 (1.53-2.92) among children. Weighted estimates of craniopharyngioma world IRs were 1.34 (1.24-1.46) in all ages and 1.44 (1.33-1.56) among children...
  47. ncbi request reprint Fractures in patients with primary idiopathic hypothyroidism
    P Vestergaard
    The Osteoporosis Clinic, Aarhus Amtssygehus, Aarhus University Hospital, Denmark
    Thyroid 10:335-40. 2000
    ..To study fracture risk and risk factors for fractures in patients with primary idiopathic hypothyroidism (ICD 10: E03.9)...
  48. ncbi request reprint Iodine in drinking water in Denmark is bound in humic substances
    Stig Andersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aalborg, Denmark
    Eur J Endocrinol 147:663-70. 2002
    ..We have previously found that iodine in drinking water is related to iodine excretion but whether iodine is present as iodide or bound in other molecules remains unknown...
  49. doi request reprint Morbidity and GH deficiency: a nationwide study
    Kirstine Stochholm
    Medical Department M Endocrinology and Diabetes, Aarhus University Hospital, Aarhus Sygehus, NBG, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 158:447-57. 2008
    ..To estimate morbidity in Denmark in all patients with GH deficiency (GHD)...
  50. doi request reprint Management of Graves' hyperthyroidism in pregnancy: focus on both maternal and foetal thyroid function, and caution against surgical thyroidectomy in pregnancy
    Peter Laurberg
    Department of Endocrinology and Medicine, Aalborg Hospital, Aalborg, Denmark
    Eur J Endocrinol 160:1-8. 2009
    ..Surgical thyroidectomy of a pregnant woman with active disease may lead to isolated foetal hyperthyroidism...
  51. ncbi request reprint Mainly the younger hypothyroid patients are referred to hospital--evidence for referral bias
    Allan Carlé
    Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Denmark
    J Clin Epidemiol 62:446-51. 2009
    ..It is unknown, to what extent such studies are referral biased. Thus, the aim of the present study was to evaluate the magnitude of selection bias in a study of patients newly diagnosed with hypothyroidism...
  52. ncbi request reprint Biologic variation is important for interpretation of thyroid function tests
    Stig Andersen
    Department of Endocrinology and Medicine, University Hospital Aalborg, Aalborg, Denmark
    Thyroid 13:1069-78. 2003
    ..The clinical importance of such small abnormalities in thyroid function in small children and pregnant women for brain development remains to be elucidated...
  53. ncbi request reprint Hypopituitarism and mortality in pituitary adenoma
    J Lindholm
    Department of Endocrinology, Aarhus University Hospital, Aalborg, Denmark
    Clin Endocrinol (Oxf) 65:51-8. 2006
    ..The purpose was to assess the relationship between mortality and pituitary function...
  54. doi request reprint Hyperthyroidism, exophthalmos, and goiter: historical notes on the orbitopathy
    Jorgen Lindholm
    Department of Endocrinology, Aarhus University Hospital, Aalborg, Denmark
    Thyroid 20:291-300. 2010
    ..Exophthalmos associated with goiter and/or symptoms of hyperthyroidism have been known since antiquity. It was not until around 1800 that a number of studies described this disorder in more detail...
  55. ncbi request reprint Reliability of studies of iodine intake and recommendations for number of samples in groups and in individuals
    Stig Andersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Arhus University Hosiptal, 9000 Aalborg, Denmark
    Br J Nutr 99:813-8. 2008
    ..In conclusion, estimating population iodine excretion requires 100-500 spot urine samples for each group or subgroup. Less than ten urine samples in an individual may be misleading...
  56. ncbi request reprint Increased risk of osteoporotic fractures in patients with Cushing's syndrome
    Peter Vestergaard
    The Osteoporosis Clinic, Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Tage Hansens Gade 2, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 146:51-6. 2002
    ..To evaluate if fracture risk was increased in patients with Cushing's syndrome due to the increased endogenous cortisol production...
  57. ncbi request reprint The metabolic syndrome is frequent in Klinefelter's syndrome and is associated with abdominal obesity and hypogonadism
    Anders Bojesen
    Medical Department M, Endocrinology and Diabetes, Aarhus University Hospital, Noerrebrogade 42 44, DK 8000, Aarhus C, Denmark
    Diabetes Care 29:1591-8. 2006
    ..We analyzed differences between patients with untreated Klinefelter's syndrome and control subjects and subsequently analyzed differences between testosterone-treated and untreated Klinefelter's syndrome patients...
  58. ncbi request reprint Iodine content of traditional Greenlandic food items and tap water in East and West Greenland
    Stig Andersen
    Department of Endocrinology and Medicine, Aalborg Hospital, Aalborg, Denmark
    Int J Circumpolar Health 61:332-40. 2002
    ..However, no measurements have been performed to determine the iodine content of Greenlandic food items, drinking water, and beverages available in East and West Greenland...
  59. ncbi request reprint Nonfunctioning pituitary adenoma: incidence, causes of death and quality of life in relation to pituitary function
    Eigil Husted Nielsen
    Department of Endocrinology, Aarhus University Hospital, 9000 Aalborg, Denmark
    Pituitary 10:67-73. 2007
    ..QOL was, however, impaired in patients who had undergone craniotomy as compared to patients undergoing transsphenoidal surgery. QOL was not reduced in hypopituitary patients or in patients receiving radiotherapy...
  60. ncbi request reprint Excess mortality in women with pituitary disease: a meta-analysis
    E H Nielsen
    Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Clin Endocrinol (Oxf) 67:693-7. 2007
    ..Increased mortality has been reported in patients with pituitary disease, with some studies showing higher standard mortality rates (SMR) in women than in men...
  61. ncbi request reprint Fracture risk is increased in patients with GH deficiency or untreated prolactinomas--a case-control study
    Peter Vestergaard
    Department of Endocrinology, Aarhus Amtssygehus, Medical Department M Endocrinology and Diabetes, Aarhus Kommunehospital, Aarhus, University Hospital, Aarhus, Denmark
    Clin Endocrinol (Oxf) 56:159-67. 2002
    ..The aim of this study was to examine fracture risk in patients with pituitary disorders with special reference to GH deficiency and hyperprolactinaemia...
  62. ncbi request reprint Incidence of GH deficiency - a nationwide study
    Kirstine Stochholm
    Medical Department M Endocrinology and Diabetes, Aarhus Sygehus, NBG, DK 8000 Aarhus C, Denmark
    Eur J Endocrinol 155:61-71. 2006
    ..Data on incidence rates are scarce in GH deficiency (GHD). Here, we estimate the incidence rate in childhood onset (CO) and adult onset (AO) GHD in Denmark...
  63. ncbi request reprint Association of tobacco smoking with goiter in a low-iodine-intake area
    Nils Knudsen
    Danish Centre for Prevention of Thyroid Diseases DanThyr, Glostrup University Hospital, Copenhagen, Denmark
    Arch Intern Med 162:439-43. 2002
    ..Goiter development depends on genetic and environmental factors. The major environmental factor is iodine intake, whereas diverging results have been published concerning the association between smoking and goiter...
  64. ncbi request reprint [Subclinical hypothyroidism--a condition that must be treated?]
    Jesper Scott Karmisholt
    Arhus Universitetshospital, Aalborg Sygehus, Medicinsk endokrinologisk afdeling
    Ugeskr Laeger 168:3113-6. 2006
    ..However, when it comes to treatment of pregnant or fertile women planning pregnancy, no doubt prevails, as normal thyroid function is important for optimal pregnancy outcome...
  65. ncbi request reprint Interferon-alpha and autoimmune thyroid disease
    Mark F Prummel
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Thyroid 13:547-51. 2003
    ..High endogenous IFN alpha levels are seen in patients infected with certain viruses. It is concluded that IFN alpha is one of the environmental factors capable of triggering the onset of AITD in genetically susceptible individuals...
  66. ncbi request reprint The association between hypoechogenicity or irregular echo pattern at thyroid ultrasonography and thyroid function in the general population
    Pernille Vejbjerg
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark
    Eur J Endocrinol 155:547-52. 2006
    ..The aim of this study was to investigate the association between echogenicity of the thyroid/irregular echo pattern, and thyroid function in the general population, i.e. subjects without overt thyroid disease...
  67. doi request reprint The impact of smoking on thyroid volume and function in relation to a shift towards iodine sufficiency
    Pernille Vejbjerg
    Department of Endocrinology and Gastroenterology, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400, Copenhagen NV, Denmark
    Eur J Epidemiol 23:423-9. 2008
    ..The effect of smoking on hormonal level was unchanged after the iodization. Thus the effect of smoking on thyroid volume seems to be dependent on iodine intake, whereas the effect on function seems mainly to depend on other factors...
  68. ncbi request reprint Dietary iodine intake and urinary iodine excretion in a Danish population: effect of geography, supplements and food choice
    Lone B Rasmussen
    Institute of Food Research and Nutrition, Danish Veterinary and Food Administration, Søborg, Denmark
    Br J Nutr 87:61-9. 2002
    ..Even individuals who followed the advice regarding intake of 200-300 g fish/week and 0.5 litres milk/d had an intake below the recommended level if living in Aalborg...
  69. ncbi request reprint Use of dietary supplements in Denmark is associated with health and former smoking
    Vibeke K Knudsen
    Institute of Food Research and Nutrition, Danish Veterinary and Food Administration, Søborg, Denmark
    Public Health Nutr 5:463-8. 2002
    ..To describe the use of dietary supplements in a group of Danish adults and to investigate the differences between users and non-users with respect to age, gender, health and lifestyle factors...
  70. ncbi request reprint Naturally occurring iodine in humic substances in drinking water in Denmark is bioavailable and determines population iodine intake
    Stig Andersen
    Department of Life Science, Aalborg University, Denmark
    Br J Nutr 99:319-25. 2008
    ..The fraction available suggests an importance of drinking water supply for population iodine intake, although this may not be adequate to estimate population iodine intake...
  71. ncbi request reprint Effect of a mandatory iodization program on thyroid gland volume based on individuals' age, gender, and preceding severity of dietary iodine deficiency: a prospective, population-based study
    Pernille Vejbjerg
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Denmark
    J Clin Endocrinol Metab 92:1397-401. 2007
    ..We aimed to evaluate prospectively the effect of 4 yr of mandatory iodization of salt (13 ppm iodine) on thyroid volume in two regional areas with respectively mild and moderate iodine deficiency...
  72. ncbi request reprint Victories and challenges in optimizing iodine intake
    Peter Laurberg
    Thyroid 14:589. 2004
  73. ncbi request reprint Relations between various measures of iodine intake and thyroid volume, thyroid nodularity, and serum thyroglobulin
    Lone B Rasmussen
    Institute of Food Research and Nutrition, The Danish Veterinary and Food Administration, Søborg, Denmark
    Am J Clin Nutr 76:1069-76. 2002
    ..Iodine intake can be measured in various ways, and each method may have advantages and disadvantages...
  74. ncbi request reprint Low goitre prevalence among users of oral contraceptives in a population sample of 3712 women
    Nils Knudsen
    Department of Internal Medicine, Bispebjerg Hospital, Copenhagen, Denmark
    Clin Endocrinol (Oxf) 57:71-6. 2002
    ..This is supported by experimental data, but a recent population study suggested decreased thyroid volumes among users of OC...
  75. ncbi request reprint Iodine intake and prevention of thyroid disorders: surveillance is needed
    Peter Laurberg
    Med J Aust 176:306-7. 2002
  76. ncbi request reprint Risk factors for goiter and thyroid nodules
    Nils Knudsen
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Denmark
    Thyroid 12:879-88. 2002
    ..The difference in age maximum in goiter prevalence suggests that monitoring of iodine deficiency disorders should ideally include a spectrum of age groups...
  77. ncbi request reprint Parity is associated with increased thyroid volume solely among smokers in an area with moderate to mild iodine deficiency
    Nils Knudsen
    Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen, Denmark
    Eur J Endocrinol 146:39-43. 2002
    ..We investigated the association between parity and thyroid volume and a possible impact of iodine deficiency and tobacco smoking on this association...
  78. ncbi request reprint Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population
    Nils Knudsen
    Endocrine Unit, Medical Clinic I, Bispebjerg Hospital, Copenhagen, Denmark
    J Clin Endocrinol Metab 90:4019-24. 2005
    ..Few data have been presented regarding an association between variations in thyroid function seen in the general population and body weight...
  79. ncbi request reprint Gender diversity in developing overweight over 35 years of Westernization in an Inuit hunter cohort and ethno-specific body mass index for evaluation of body-weight abnormalities
    Stig Andersen
    Department of Medicine, Queen Ingrids Hospital, Nuuk, Greenland
    Eur J Endocrinol 151:735-40. 2004
    ..To establish an Inuit body mass index (BMI) norm from a healthy, not malnourished, pure Inuit population and to investigate the development of overweight in the Inuit in Greenland...
  80. ncbi request reprint Patients on appropriate T(4) replacement are as content as they would be on any thyroid hormone
    Peter Laurberg
    J Clin Endocrinol Metab 89:2507; author reply 2507-8. 2004
  81. ncbi request reprint Long-term parathyroid- and c-cell function after radioiodine for benign thyroid diseases
    Lene S Mortensen
    Viborg County Hospital, Department of Internal Medicine, Viborg, Denmark
    Basic Clin Pharmacol Toxicol 97:22-8. 2005
    ..Radioiodine in doses used for benign thyroid diseases appears safe with regard to parathyroid hormone and calcitonin secretion...
  82. ncbi request reprint Prevention in thyroidology
    Peter Laurberg
    Thyroid 12:837. 2002