H Deng

Summary

Publications

  1. ncbi Genetic variants and animal models in SNCA and Parkinson disease
    Hao Deng
    Center for Experimental Medicine and Department of Neurology, The Third Xiangya Hospital, Central South University, Tongzipo Road 138, Changsha, Hunan 410013, PR China Electronic address
    Ageing Res Rev 15:161-76. 2014
  2. ncbi Molecular genetics of congenital nuclear cataract
    Hao Deng
    Center for Experimental Medicine and Department of Neurology, The Third Xiangya Hospital, Central South University, Tongzipo Road 138, Changsha, Hunan 410013, China Electronic address
    Eur J Med Genet 57:113-22. 2014
  3. ncbi Genetics, molecular biology, and phenotypes of x-linked epilepsy
    Hao Deng
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Tongzipo Road 138, Changsha, Hunan, 410013, China
    Mol Neurobiol 49:1166-80. 2014
  4. pmc Novel ATPase Cu(2+) transporting beta polypeptide mutations in Chinese families with Wilson's disease
    Shaojuan Gu
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, China
    PLoS ONE 8:e66526. 2013
  5. pmc Acute myelitis in a patient with vogt-koyanagi-harada disease: case report and review of the literature
    Shaojuan Gu
    Department of Neurology and Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, China
    J Clin Neurol 9:61-4. 2013
  6. ncbi The molecular biology of genetic-based epilepsies
    Hao Deng
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Tongzipo Road 138, Changsha, Hunan, 410013, People s Republic of China
    Mol Neurobiol 49:352-67. 2014
  7. pmc Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease
    Kai Gao
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, 138 Tongzipo Road, Changsha, Hunan 410013, China
    BMC Neurol 13:125. 2013
  8. doi The VPS35 gene and Parkinson's disease
    Hao Deng
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, China
    Mov Disord 28:569-75. 2013
  9. doi F-box only protein 7 gene in parkinsonian-pyramidal disease
    Hao Deng
    Center for Experimental Medicine, Third Xiangya Hospital, Central South University, Changsha, Hunan, China
    JAMA Neurol 70:20-4. 2013
  10. doi The genetics of Tourette syndrome
    Hao Deng
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, 138 Tongzipo Road, Changsha, Hunan 410013, China
    Nat Rev Neurol 8:203-13. 2012

Collaborators

Detail Information

Publications17

  1. ncbi Genetic variants and animal models in SNCA and Parkinson disease
    Hao Deng
    Center for Experimental Medicine and Department of Neurology, The Third Xiangya Hospital, Central South University, Tongzipo Road 138, Changsha, Hunan 410013, PR China Electronic address
    Ageing Res Rev 15:161-76. 2014
    ..Further understanding of its role in the pathogenesis of PD through various genetic techniques and animal models will likely provide new insights into our understanding, therapy and prevention of PD. ..
  2. ncbi Molecular genetics of congenital nuclear cataract
    Hao Deng
    Center for Experimental Medicine and Department of Neurology, The Third Xiangya Hospital, Central South University, Tongzipo Road 138, Changsha, Hunan 410013, China Electronic address
    Eur J Med Genet 57:113-22. 2014
    ..In this review, we highlight identified genetic mutations that account for congenital nuclear cataract. Our review may be helpful for genetic counseling and prenatal diagnosis. ..
  3. ncbi Genetics, molecular biology, and phenotypes of x-linked epilepsy
    Hao Deng
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Tongzipo Road 138, Changsha, Hunan, 410013, China
    Mol Neurobiol 49:1166-80. 2014
    ..This information may provide us a better understanding of the pathogenesis of X-linked epilepsy and may contribute to clinical diagnosis and therapy of epilepsy. ..
  4. pmc Novel ATPase Cu(2+) transporting beta polypeptide mutations in Chinese families with Wilson's disease
    Shaojuan Gu
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, China
    PLoS ONE 8:e66526. 2013
    ..Our results revealed that the genetic cause of 18 Chinese families with WD and ATP7B deficiency-induce apoptosis may result from imbalance in cell cycle and lipid metabolism pathway. ..
  5. pmc Acute myelitis in a patient with vogt-koyanagi-harada disease: case report and review of the literature
    Shaojuan Gu
    Department of Neurology and Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, China
    J Clin Neurol 9:61-4. 2013
    ..Vogt-Koyanagi-Harada (VKH) disease is characterized by bilateral granulomatous uveitis with neurologic, auditory, and dermatologic manifestations. However, acute myelitis complicating VKH disease has rarely been reported...
  6. ncbi The molecular biology of genetic-based epilepsies
    Hao Deng
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Tongzipo Road 138, Changsha, Hunan, 410013, People s Republic of China
    Mol Neurobiol 49:352-67. 2014
    ..These progresses have improved our understanding of the complex neurological disorder. ..
  7. pmc Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease
    Kai Gao
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, 138 Tongzipo Road, Changsha, Hunan 410013, China
    BMC Neurol 13:125. 2013
    ..The F-box protein 42 gene (FBXO42), a paralog of the FBXO7 gene, is involved in the ubiquitin-proteasome system that may play a role in the pathogenesis of PD...
  8. doi The VPS35 gene and Parkinson's disease
    Hao Deng
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, China
    Mov Disord 28:569-75. 2013
    ..Further understanding of these mechanisms will undoubtedly provide new insights into the pathogenic mechanisms of PD and may lead to prevention and better treatment of the disorder...
  9. doi F-box only protein 7 gene in parkinsonian-pyramidal disease
    Hao Deng
    Center for Experimental Medicine, Third Xiangya Hospital, Central South University, Changsha, Hunan, China
    JAMA Neurol 70:20-4. 2013
    ....
  10. doi The genetics of Tourette syndrome
    Hao Deng
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, 138 Tongzipo Road, Changsha, Hunan 410013, China
    Nat Rev Neurol 8:203-13. 2012
    ..In this Review, we provide an overview of the genetics of Tourette syndrome and highlight how this knowledge has improved our understanding of the possible pathogenic mechanisms of this neurological disorder...
  11. doi LINGO1 variants in essential tremor and Parkinson's disease
    H Deng
    Center for Experimental Medicine, Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, HN, China
    Acta Neurol Scand 125:1-7. 2012
    ..Here, we review published reports of the LINGO1 variants in ET and PD in an attempt to better understand the molecular and pathogenic relationship of LINGO1 to the two disorders...
  12. ncbi Confirmation and refinement of a genetic locus for disseminated superficial actinic porokeratosis (DSAP1) at 12q23.2-24.1
    L Q Wu
    National Laboratory of Medical Genetics, Xiangya Second Hospital, Central South University, Changsha, Hunan 410078, China
    Br J Dermatol 150:999-1004. 2004
    ..Our previous study has identified two loci for disseminated superficial actinic porokeratosis (DSAP), but the genes responsible are still unknown...
  13. doi Examination of the MSX1 gene in patients with Parkinson's disease
    H Deng
    Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, China
    Acta Neurol Scand 120:442-4. 2009
    ..The muscle segment homeobox drosophila homolog of 1 gene (MSX1) is a major upstream regulator of the dopaminergic neuronal subtype specification...
  14. ncbi TAp63 suppress metastasis via miR-133b in colon cancer cells
    C W Lin
    Department of General Surgery, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, People s Republic of China
    Br J Cancer 110:2310-20. 2014
    ..It has been shown to activate gene transcription depending on the transcription domain and to be closely related with metastasis. In this study, we demonstrate that TAp63 suppresses metastasis in colon cancer cells through microRNA-133b...
  15. doi The role of IL-12 and TNF-alpha in AIDP and AMAN
    H Deng
    Department of Neurology, The First Hospital, Jilin University, Changchun, China
    Eur J Neurol 15:1100-5. 2008
    ....
  16. ncbi [Gly40Ser mutation of glucagon receptor gene and NIDDM in Han nationality]
    H Deng
    National Lab of Medical Genetics of China, Central South University, Changsha 410078, China
    Hunan Yi Ke Da Xue Xue Bao 26:291-3. 2001
    ..To ascertain whether Gly40Ser mutation in exon 2 of glucagon receptor (GCG-R) gene is associated with late-onset non-insulin-dependent diabetes millitus (NIDDM) in Chinese...
  17. ncbi A novel locus (DSAP2) for disseminated superficial actinic porokeratosis maps to chromosome 15q25.1-26.1
    K Xia
    National Laboratory of Medical Genetics, Department of Dermatology, Xiangya Hospital, Changsha, Hunan 410078, China
    Br J Dermatol 147:650-4. 2002
    ..The first locus for DSAP was localized to chromosome 12q23.2-24.1, but no gene responsible for porokeratosis has been identified to date...