Laetitia Delort

Summary

Publications

  1. doi request reprint Zinc-α2-glycoprotein: a proliferative factor for breast cancer? In vitro study and molecular mechanisms
    Laetitia Delort
    Clermont University, University of Auvergne, UFR Pharmacy, Laboratory SVFp, F 63000 Clermont Ferrand, France
    Oncol Rep 29:2025-9. 2013
  2. pmc Reciprocal interactions between breast tumor and its adipose microenvironment based on a 3D adipose equivalent model
    Laetitia Delort
    Clermont Universite, Universite d Auvergne, UFR Pharmacie, Laboratoire SVFp, Clermont Ferrand, France
    PLoS ONE 8:e66284. 2013
  3. doi request reprint Effect of histone deacetylase and DNA methyltransferase inhibitors on the expression of the androgen receptor gene in androgen-independent prostate cancer cell lines
    Barbora Fialova
    Laboratory of Molecular Pathology, Department of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacky University Olomouc, 775 15 Olomouc, Czech Republic
    Oncol Rep 29:2039-45. 2013
  4. doi request reprint New insights into anticarcinogenic properties of adiponectin: a potential therapeutic approach in breast cancer?
    Laetitia Delort
    Clermont Universite, Universite d Auvergne, UFR Pharmacie, Laboratoire SVFp, 28 Place Henri Dunant, F 63000 Clermont Ferrand, France
    Vitam Horm 90:397-417. 2012
  5. ncbi request reprint Differential expression of genes induced by resveratrol in human breast cancer cell lines
    Ludovic Le Corre
    Département d Oncogénétique, Centre Jean Perrin, CBRV, INSERM UMR484 UdA, Clermont Ferrand, France
    Nutr Cancer 56:193-203. 2006
  6. ncbi request reprint Association between genetic polymorphisms and ovarian cancer risk
    Laetitia Delort
    Département d Oncogénétique du Centre Jean Perrin, CBRV, Clermont Ferrand, France
    Anticancer Res 28:3079-81. 2008
  7. doi request reprint [Leptin: Involvement in the pathophysiology of breast cancer]
    Florence Caldefie-Chezet
    Clermont Universite, Universite d Auvergne, UFR Pharmacie, 28, Place Henri Dunant, 63000 Clermont Ferrand, France
    Ann Endocrinol (Paris) 74:90-101. 2013
  8. ncbi request reprint Leptin induces a proliferative response in breast cancer cells but not in normal breast cells
    Virginie Dubois
    a Clermont Université, Universite d Auvergne, Unite de Nutrition Humaine, BP10448, F 63000 Clermont Ferrand, France and INRA, UMR 1019, UNH, ECREIN, CRNH Auvergne, Clermont Ferrand, France
    Nutr Cancer 66:645-55. 2014
  9. pmc Breast cancer and obesity: in vitro interferences between adipokines and proangiogenic features and/or antitumor therapies?
    Virginie Dubois
    Clermont Universite, Universite d Auvergne, UFR Pharmacie, Laboratoire SVFp, Clermont Ferrand, France
    PLoS ONE 8:e58541. 2013
  10. pmc DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk
    Dominique Bernard-Gallon
    Département d Oncogénétique du Centre Jean Perrin, EA 2416 CBRV, 28 Place Henri Dunant, B, P, 38, 63001 Clermont Ferrand Cedex 01, France
    Mol Cancer 7:36. 2008

Collaborators

Detail Information

Publications12

  1. doi request reprint Zinc-α2-glycoprotein: a proliferative factor for breast cancer? In vitro study and molecular mechanisms
    Laetitia Delort
    Clermont University, University of Auvergne, UFR Pharmacy, Laboratory SVFp, F 63000 Clermont Ferrand, France
    Oncol Rep 29:2025-9. 2013
    ..ZAG was able to modulate gene and protein expression involved in the apoptotic response. However, further studies are required to fully elucidate the effects of ZAG on the proliferation of mammary cells...
  2. pmc Reciprocal interactions between breast tumor and its adipose microenvironment based on a 3D adipose equivalent model
    Laetitia Delort
    Clermont Universite, Universite d Auvergne, UFR Pharmacie, Laboratoire SVFp, Clermont Ferrand, France
    PLoS ONE 8:e66284. 2013
    ..This tridimensional adipose model provides new insights into the interactions between breast cancer cells and their adipose microenvironment, and provides a tool to develop new drugs for the treatment of both cancer and obesity...
  3. doi request reprint Effect of histone deacetylase and DNA methyltransferase inhibitors on the expression of the androgen receptor gene in androgen-independent prostate cancer cell lines
    Barbora Fialova
    Laboratory of Molecular Pathology, Department of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacky University Olomouc, 775 15 Olomouc, Czech Republic
    Oncol Rep 29:2039-45. 2013
    ..In the AR gene promoter, the location and density of deme-thylated CpGs indicated the existence of distinct promoter hot spot that could be a target of AR gene inactivation therapy of CaP patients during androgen deprivation...
  4. doi request reprint New insights into anticarcinogenic properties of adiponectin: a potential therapeutic approach in breast cancer?
    Laetitia Delort
    Clermont Universite, Universite d Auvergne, UFR Pharmacie, Laboratoire SVFp, 28 Place Henri Dunant, F 63000 Clermont Ferrand, France
    Vitam Horm 90:397-417. 2012
    ..This therapeutic approach may be of particular significance for obese patients. The beneficial effects of adiponectin and its possible therapeutic applications will be discussed in this review...
  5. ncbi request reprint Differential expression of genes induced by resveratrol in human breast cancer cell lines
    Ludovic Le Corre
    Département d Oncogénétique, Centre Jean Perrin, CBRV, INSERM UMR484 UdA, Clermont Ferrand, France
    Nutr Cancer 56:193-203. 2006
    ..This effect of RES on the gene expression appears in correlation with chemoprevention activities of RES described previously. RES is also found to be more active in ER+ than ER- cells...
  6. ncbi request reprint Association between genetic polymorphisms and ovarian cancer risk
    Laetitia Delort
    Département d Oncogénétique du Centre Jean Perrin, CBRV, Clermont Ferrand, France
    Anticancer Res 28:3079-81. 2008
    ..The etiology of ovarian cancer is not fully understood. Polymorphisms in low penetrance genes involved in carcinogen and estrogen metabolism are hypothesized to play a role in the initiation of carcinogenesis...
  7. doi request reprint [Leptin: Involvement in the pathophysiology of breast cancer]
    Florence Caldefie-Chezet
    Clermont Universite, Universite d Auvergne, UFR Pharmacie, 28, Place Henri Dunant, 63000 Clermont Ferrand, France
    Ann Endocrinol (Paris) 74:90-101. 2013
    ....
  8. ncbi request reprint Leptin induces a proliferative response in breast cancer cells but not in normal breast cells
    Virginie Dubois
    a Clermont Université, Universite d Auvergne, Unite de Nutrition Humaine, BP10448, F 63000 Clermont Ferrand, France and INRA, UMR 1019, UNH, ECREIN, CRNH Auvergne, Clermont Ferrand, France
    Nutr Cancer 66:645-55. 2014
    ..Autoregulation induced by leptin, relationship with estrogen pathway, and proliferative and antiapoptic activity in breast cancer cells may explain that obesity-associated hyperleptinemia may be a breast cancer risk factor. ..
  9. pmc Breast cancer and obesity: in vitro interferences between adipokines and proangiogenic features and/or antitumor therapies?
    Virginie Dubois
    Clermont Universite, Universite d Auvergne, UFR Pharmacie, Laboratoire SVFp, Clermont Ferrand, France
    PLoS ONE 8:e58541. 2013
    ..The evidence suggests adipokines influence breast cancer issue and could play a significant role, especially in obese patients for which hyperleptinemia, hypoadiponectinemia and increased metastatic potential are described...
  10. pmc DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk
    Dominique Bernard-Gallon
    Département d Oncogénétique du Centre Jean Perrin, EA 2416 CBRV, 28 Place Henri Dunant, B, P, 38, 63001 Clermont Ferrand Cedex 01, France
    Mol Cancer 7:36. 2008
    ..This study enabled us to show an increase in risk of breast cancer with no oral contraceptive users and with women exhibiting a waist-to-hip ratio (WHR) > 0.85 for Asn homozygous for ERCC2 312...
  11. doi request reprint Rad50 c.687delT does not contribute significantly to familial breast cancer in a French population
    Nancy Uhrhammer
    Laboratoire Diagnostic Génétique et Moléculaire, Centre Jean Perrin, Clermont Ferrand, France
    Cancer Epidemiol Biomarkers Prev 18:684-5. 2009
    ..These data together suggest that although founder mutations may make Rad50 a significant breast cancer risk factor in certain populations, it is not a factor in others...
  12. ncbi request reprint Soya phytonutrients act on a panel of genes implicated with BRCA1 and BRCA2 oncosuppressors in human breast cell lines
    Bertrand Caetano
    Département d Oncogénétique du Centre Jean Perrin, INSERM UMR 484 UdA, Centre Biomédical de Recherche et de Valorisation, 28 Place Henri Dunant, B P 38, 63 001 Clermont Ferrand Cedex 01, France
    Br J Nutr 95:406-13. 2006
    ..We observed that, in response to treatment, many of these genes were overexpressed in the breast cancer cell lines (MCF-7 and MDA-MB-231) but not in the dystrophic cell line (MCF10a)...