D Delev

Summary

Publications

  1. ncbi Modelling and expression studies of two novel mutations causing factor V deficiency
    Daniel Delev
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Thromb Haemost 100:766-72. 2008
  2. ncbi Factor 5 mutation profile in German patients with homozygous and heterozygous factor V deficiency
    D Delev
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany
    Haemophilia 15:1143-53. 2009
  3. ncbi Impact of polymorphisms of the major histocompatibility complex class II, interleukin-10, tumor necrosis factor-alpha and cytotoxic T-lymphocyte antigen-4 genes on inhibitor development in severe hemophilia A
    A Pavlova
    Experimental Heamatology and Transfusion Medicine, University of Clinic Bonn, Sigmund Freud Str 25, Germany
    J Thromb Haemost 7:2006-2015. 2009
  4. ncbi Heterozygous large deletions of Factor 8 gene in females identified by multiplex PCR-LC
    A Pavlova
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany
    Haemophilia 14:599-606. 2008

Collaborators

Detail Information

Publications4

  1. ncbi Modelling and expression studies of two novel mutations causing factor V deficiency
    Daniel Delev
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Thromb Haemost 100:766-72. 2008
    ..Thus, both the data from the short duration molecular dynamic simulation and from expression analysis indicate alterations of the FV protein variants that explain the clinical phenotype...
  2. ncbi Factor 5 mutation profile in German patients with homozygous and heterozygous factor V deficiency
    D Delev
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany
    Haemophilia 15:1143-53. 2009
    ..Identifying the molecular basis of mutations underlying this rare coagulation disorder will allow more insight into the mechanisms involved in the variable clinical phenotypes of patients with FV deficiency...
  3. ncbi Impact of polymorphisms of the major histocompatibility complex class II, interleukin-10, tumor necrosis factor-alpha and cytotoxic T-lymphocyte antigen-4 genes on inhibitor development in severe hemophilia A
    A Pavlova
    Experimental Heamatology and Transfusion Medicine, University of Clinic Bonn, Sigmund Freud Str 25, Germany
    J Thromb Haemost 7:2006-2015. 2009
    ..The higher frequencies of the 308G>A polymorphism in TNF-alpha and 1082A>G in IL-10 in inhibitor patients confirmed the earlier published data. The CT60 single-nucleotide polymorphism in CTLA-4 is of apparently less importance...
  4. ncbi Heterozygous large deletions of Factor 8 gene in females identified by multiplex PCR-LC
    A Pavlova
    Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany
    Haemophilia 14:599-606. 2008
    ..In conclusion, the multiplex PCR-LC technique represents a rapid, simple and reliable method for detection of heterozygous large deletions in female carriers...