Hernando A del Portillo

Summary

Publications

  1. pmc Strain-specific spleen remodelling in Plasmodium yoelii infections in Balb/c mice facilitates adherence and spleen macrophage-clearance escape
    Lorena Martin-Jaular
    Barcelona Centre for International Health Research, Barcelona, Spain
    Cell Microbiol 13:109-22. 2011
  2. pmc Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections
    Lorena Martin-Jaular
    Poverty Related Diseases, Barcelona Centre for International Health Research, Barcelona, Spain
    PLoS ONE 6:e26588. 2011
  3. doi request reprint Reticulocyte-prone malaria parasites predominantly invade CD71hi immature cells: implications for the development of an in vitro culture for Plasmodium vivax
    Lorena Martin-Jaular
    ICREA at Barcelona Centre for International H ealth Research CRESIB, Hospital Clínic Universitat de Barcelona ISGlobal, Barcelona, Spain
    Malar J 12:434. 2013
  4. doi request reprint Talking to each other to initiate sexual differentiation
    Hernando A del Portillo
    ICREA at Barcelona Centre for International Health Research CRESIB, Hospital Clínic Universitat de Barcelona, 08036 Barcelona, Spain
    Cell 153:945-7. 2013
  5. doi request reprint The role of the spleen in malaria
    Hernando A del Portillo
    Barcelona Centre for International Health Research CRESIB, Hospital Clínic Universitat de Barcelona, Barcelona, Spain
    Cell Microbiol 14:343-55. 2012
  6. pmc Comparison of diagnostic methods for the detection and quantification of the four sympatric Plasmodium species in field samples from Papua New Guinea
    Anna Rosanas-Urgell
    Papua New Guinea Insitute of Medical Research, Madang 511, Papua New Guinea
    Malar J 9:361. 2010
  7. pmc Naturally-acquired humoral immune responses against the N- and C-termini of the Plasmodium vivax MSP1 protein in endemic regions of Brazil and Papua New Guinea using a multiplex assay
    Carmen Fernandez-Becerra
    Barcelona Centre for International Health Research CRESIB, Hospital Clinic IDIBAPS, Universitat de Barcelona, Rosello 132, 08036 Barcelona, Spain
    Malar J 9:29. 2010
  8. doi request reprint Plasmodium vivax and the importance of the subtelomeric multigene vir superfamily
    Carmen Fernandez-Becerra
    Barcelona Centre for International Health Research, Hospital Clinic IDIBAPS, Universitat de Barcelona, Rosello 132, 08036 Barcelona, Spain
    Trends Parasitol 25:44-51. 2009
  9. pmc Plasmodium vivax: comparison of immunogenicity among proteins expressed in the cell-free systems of Escherichia coli and wheat germ by suspension array assays
    Edmilson Rui
    Barcelona Centre for International Health Research CRESIB, Hospital Clinic IDIBAPS, Universitat de Barcelona, Roselló 153, 1a planta, 08036, Barcelona, Spain
    Malar J 10:192. 2011
  10. pmc A new computational approach redefines the subtelomeric vir superfamily of Plasmodium vivax
    Francisco Javier López
    Barcelona Centre for International Health Research, CRESIB, Hospital Clínic Universitat de Barcelona, Roselló 153, 1a planta CEK building, 08036 Barcelona, Spain
    BMC Genomics 14:8. 2013

Collaborators

Detail Information

Publications14

  1. pmc Strain-specific spleen remodelling in Plasmodium yoelii infections in Balb/c mice facilitates adherence and spleen macrophage-clearance escape
    Lorena Martin-Jaular
    Barcelona Centre for International Health Research, Barcelona, Spain
    Cell Microbiol 13:109-22. 2011
    ....
  2. pmc Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections
    Lorena Martin-Jaular
    Poverty Related Diseases, Barcelona Centre for International Health Research, Barcelona, Spain
    PLoS ONE 6:e26588. 2011
    ..yoelli 17XL. To our knowledge, this is the first report of immune responses elicited by exosomes derived from reticulocytes opening new avenues for the modulation of anti-malaria responses...
  3. doi request reprint Reticulocyte-prone malaria parasites predominantly invade CD71hi immature cells: implications for the development of an in vitro culture for Plasmodium vivax
    Lorena Martin-Jaular
    ICREA at Barcelona Centre for International H ealth Research CRESIB, Hospital Clínic Universitat de Barcelona ISGlobal, Barcelona, Spain
    Malar J 12:434. 2013
    ..yoelii 17X, CD71 expression in erythroid cells (TER119+) was assessed and in vitro culture of P. yoelii 17X was attempted by adding reticulocytes highly expressing CD71...
  4. doi request reprint Talking to each other to initiate sexual differentiation
    Hernando A del Portillo
    ICREA at Barcelona Centre for International Health Research CRESIB, Hospital Clínic Universitat de Barcelona, 08036 Barcelona, Spain
    Cell 153:945-7. 2013
    ..Two studies by Regev-Rudzki et al. and Mantel et al. reveal an unexpected role for cell-cell communication using extracellular vesicles in triggering the commitment of malaria parasites toward sexual differentiation...
  5. doi request reprint The role of the spleen in malaria
    Hernando A del Portillo
    Barcelona Centre for International Health Research CRESIB, Hospital Clínic Universitat de Barcelona, Barcelona, Spain
    Cell Microbiol 14:343-55. 2012
    ..Here, the role of the spleen in malaria is reviewed with special emphasis in lessons learned from human infections and mouse models...
  6. pmc Comparison of diagnostic methods for the detection and quantification of the four sympatric Plasmodium species in field samples from Papua New Guinea
    Anna Rosanas-Urgell
    Papua New Guinea Insitute of Medical Research, Madang 511, Papua New Guinea
    Malar J 9:361. 2010
    ..Despite great advantages of light microscopy (LM) for malaria diagnosis, its limited sensitivity is a critical shortfall for epidemiological studies. Robust molecular diagnostics tools are thus needed...
  7. pmc Naturally-acquired humoral immune responses against the N- and C-termini of the Plasmodium vivax MSP1 protein in endemic regions of Brazil and Papua New Guinea using a multiplex assay
    Carmen Fernandez-Becerra
    Barcelona Centre for International Health Research CRESIB, Hospital Clinic IDIBAPS, Universitat de Barcelona, Rosello 132, 08036 Barcelona, Spain
    Malar J 9:29. 2010
    ....
  8. doi request reprint Plasmodium vivax and the importance of the subtelomeric multigene vir superfamily
    Carmen Fernandez-Becerra
    Barcelona Centre for International Health Research, Hospital Clinic IDIBAPS, Universitat de Barcelona, Rosello 132, 08036 Barcelona, Spain
    Trends Parasitol 25:44-51. 2009
    ..vivax and from data gathered from experimental infections in reticulocyte-prone non-lethal malaria parasites and natural P. vivax infections...
  9. pmc Plasmodium vivax: comparison of immunogenicity among proteins expressed in the cell-free systems of Escherichia coli and wheat germ by suspension array assays
    Edmilson Rui
    Barcelona Centre for International Health Research CRESIB, Hospital Clinic IDIBAPS, Universitat de Barcelona, Roselló 153, 1a planta, 08036, Barcelona, Spain
    Malar J 10:192. 2011
    ..However, no comparative analysis of both systems is presently available nor the usage of suspension array technologies, which offer nearly solution phase kinetics...
  10. pmc A new computational approach redefines the subtelomeric vir superfamily of Plasmodium vivax
    Francisco Javier López
    Barcelona Centre for International Health Research, CRESIB, Hospital Clínic Universitat de Barcelona, Roselló 153, 1a planta CEK building, 08036 Barcelona, Spain
    BMC Genomics 14:8. 2013
    ....
  11. pmc Plasmodium vivax malaria in Mali: a study from three different regions
    Maria Bernabeu
    Barcelona Centre for International Health Research, Hospital Clínic Universitat de Barcelona, Barcelona, Spain
    Malar J 11:405. 2012
    ..Recent reports, however, suggest the circulation of P. vivax in sub-Saharan Africa...
  12. doi request reprint Imaging of the spleen in malaria
    Mireia Ferrer
    Barcelona Centre for International Health Research CRESIB, Hospital Clínic Universitat de Barcelona ISGlobal, Barcelona, Spain
    Parasitol Int 63:195-205. 2014
    ....
  13. doi request reprint Red blood cells derived from peripheral blood and bone marrow CD34⁺ human haematopoietic stem cells are permissive to Plasmodium parasites infection
    Carmen Fernandez-Becerra
    Barcelona Centre for International Health Research, Hospital Clinic, Universitat de Barcelona, BarcelonaSpain, Spain
    Mem Inst Oswaldo Cruz 108:801-3. 2013
    ..Moreover, these reticulocytes and mature red blood cells express surface markers for entrance of malaria parasites contain adult haemoglobin and are also permissive to invasion by P. vivax and Plasmodium falciparum parasites...
  14. pmc Increased expression levels of the pvcrt-o and pvmdr1 genes in a patient with severe Plasmodium vivax malaria
    Carmen Fernandez-Becerra
    Barcelona Centre for International Health Research CRESIB, Hospital Clinic IDIBAPS, Universitat de Barcelona, Rosello 132, 4a planta, 08036, Barcelona, Spain
    Malar J 8:55. 2009
    ..There are increasing reports of severe clinical cases exclusively associated with Plasmodium vivax infections. Notably, this severity has been recently suggested to be associated with chloroquine resistance...