Mauro Degli Esposti

Summary

Publications

  1. pmc Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity
    M D Esposti
    Cancer Research Campaign Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Manchester M13 9PT, United Kingdom
    Mol Cell Biol 21:7268-76. 2001
  2. ncbi request reprint Sequence and functional similarities between pro-apoptotic Bid and plant lipid transfer proteins
    Mauro Degli Esposti
    Cancer Research Campaign Molecular Pharmacology Group, School of Biological Sciences, Stopford Building, University of Manchester, M13 9PT, Manchester, UK
    Biochim Biophys Acta 1553:331-40. 2002
  3. ncbi request reprint The roles of Bid
    M Degli Esposti
    Cancer Research Campaign Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Apoptosis 7:433-40. 2002
  4. ncbi request reprint The mitochondrial battlefield and membrane lipids during cell death signalling
    Mauro Degli Esposti
    Cancer Research UK Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Ital J Biochem 52:43-50. 2003
  5. ncbi request reprint Measuring mitochondrial reactive oxygen species
    Mauro Degli Esposti
    Cancer Research Campaign Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Methods 26:335-40. 2002
  6. ncbi request reprint Mitochondrial membrane permeabilisation by Bax/Bak
    Mauro Degli Esposti
    Cancer Research UK Cellular and Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, G38 Stopford Building, Oxford Road, Manchester M134 9PT, UK
    Biochem Biophys Res Commun 304:455-61. 2003
  7. ncbi request reprint Post-translational modification of Bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3
    Mauro Degli Esposti
    Cancer Research UK Cellular and Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Stopford Bldg, Oxford Road, Manchester M13 9PT, UK
    J Biol Chem 278:15749-57. 2003
  8. doi request reprint Organelle intermixing and membrane scrambling in cell death
    Mauro Degli Esposti
    Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom
    Methods Enzymol 442:421-38. 2008

Collaborators

  • M Degli Esposti
  • M D Esposti
  • J A Hickman
  • J T Erler
  • C Dive

Detail Information

Publications8

  1. pmc Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity
    M D Esposti
    Cancer Research Campaign Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Manchester M13 9PT, United Kingdom
    Mol Cell Biol 21:7268-76. 2001
    ..Thus, Bid is likely to be involved in the transport and recycling of mitochondrial phospholipids. We discuss how this new role of Bid may relate to its proapoptotic action...
  2. ncbi request reprint Sequence and functional similarities between pro-apoptotic Bid and plant lipid transfer proteins
    Mauro Degli Esposti
    Cancer Research Campaign Molecular Pharmacology Group, School of Biological Sciences, Stopford Building, University of Manchester, M13 9PT, Manchester, UK
    Biochim Biophys Acta 1553:331-40. 2002
    ..The hypothesis is discussed in relation to current models for the integrated action of pro-apoptotic proteins of the Bcl-2 family...
  3. ncbi request reprint The roles of Bid
    M Degli Esposti
    Cancer Research Campaign Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Apoptosis 7:433-40. 2002
    ....
  4. ncbi request reprint The mitochondrial battlefield and membrane lipids during cell death signalling
    Mauro Degli Esposti
    Cancer Research UK Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Ital J Biochem 52:43-50. 2003
    ..In addition, it is suggested that pro-apoptotic Bid may modulate key processes linking lipid constituents of mitochondrial membranes to lipid re-modelling that are altered early by death receptor signalling...
  5. ncbi request reprint Measuring mitochondrial reactive oxygen species
    Mauro Degli Esposti
    Cancer Research Campaign Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Methods 26:335-40. 2002
    ..Advice is also provided to aid the interpretation of cellular data with respect to the contribution of oxygen radical production by different components of the mitochondrial respiratory chain...
  6. ncbi request reprint Mitochondrial membrane permeabilisation by Bax/Bak
    Mauro Degli Esposti
    Cancer Research UK Cellular and Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, G38 Stopford Building, Oxford Road, Manchester M134 9PT, UK
    Biochem Biophys Res Commun 304:455-61. 2003
    ..We also consider the emerging information that lipid-protein interactions may be crucial to the actions of Bax and Bak...
  7. ncbi request reprint Post-translational modification of Bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3
    Mauro Degli Esposti
    Cancer Research UK Cellular and Molecular Pharmacology Group, School of Biological Sciences, University of Manchester, Stopford Bldg, Oxford Road, Manchester M13 9PT, UK
    J Biol Chem 278:15749-57. 2003
    ..Contrary to rBid, isolated Bid was resistant to cleavage by caspase 3, yet was readily cleaved within the cytosolic milieu. Our data suggest that one or more distinct cellular mechanisms regulate Bid cleavage by caspases 8 and 3 in situ...
  8. doi request reprint Organelle intermixing and membrane scrambling in cell death
    Mauro Degli Esposti
    Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom
    Methods Enzymol 442:421-38. 2008
    ....