Applicability and generalisability of the results of systematic reviews to public health practice and policy: a systematic reviewNizar Ahmad
Centre d Epidemiologie Clinique, Hopital Hotel Dieu, AP HP Assistance Publique des Hôpitaux de Paris, 1 Place du Parvis Notre Dame, Paris 75181, France
Trials 11:20. 2010
..e., whether the results of a trial can be reasonably applied or generalized to a definable group of patients in a particular setting in routine practice, also called external validity or generalisability)...
Reviews assessing the quality or the reporting of randomized controlled trials are increasing over time but raised questions about how quality is assessedAgnes Dechartres
Centre for Statistics in Medicine, University of Oxford, Oxford, UK
J Clin Epidemiol 64:136-44. 2011
..Many reviews specifically aimed to assess the quality of randomized controlled trials (RCTs). We evaluated the quality of reporting in such reviews...
- Inadequate planning and reporting of adjudication committees in clinical trials: recommendation proposal
Agnes Dechartres
INSERM U738, Paris, France
J Clin Epidemiol 62:695-702. 2009
..We aimed to assess the reporting and functioning of ACs (synonyms: clinical event committees, endpoint committees) in clinical trials...
- Outcomes of empirical eating disorder phenotypes in a clinical female sample: results from a latent class analysis
Agnes Dechartres
Maison des Adolescents, PSIGIAM, U669, INSERM, Paris, France
Psychopathology 44:12-20. 2011
..To empirically classify phenotypes of eating disorders (ED) using latent class analysis (LCA), and to validate this classification based on clinical outcomes...
- Knee arthroplasty: disabilities in comparison to the general population and to hip arthroplasty using a French national longitudinal survey
Agnes Dechartres
INSERM, U738, Paris, France
PLoS ONE 3:e2561. 2008
..A secondary objective was to compare the level of disabilities of people with knee to people with hip arthroplasty...
- In obese and non-obese adults, the cis-regulatory rs361072 promoter variant of PIK3CB is associated with insulin resistance not with type 2 diabetes
Karine Clement
Endocrinology and Nutrition Department, Pitie Salpetriere Hospital, Paris, France
Mol Genet Metab 96:129-32. 2009
..Allele C of rs361072 is associated with a protection from IR in obese and non-obese adults, but has no significant effect, however, on diabetes risk in obese or non-obese Europeans...
- Single-center trials show larger treatment effects than multicenter trials: evidence from a meta-epidemiologic study
Agnes Dechartres
U738 INSERM, Paris, France
Ann Intern Med 155:39-51. 2011
..A recent study suggested that results of single-center trials are frequently contradicted when similar trials are performed in multicenter settings...
- Mycobacterium genavense infections: a retrospective multicenter study in France, 1996-2007
Pierre Charles
Universite Paris Descartes, Hopital Necker Enfants Malades, Paris, France
Medicine (Baltimore) 90:223-30. 2011
..The 1-year survival rate was 72%.The prognosis of M. genavense infection in HIV-infected patients has dramatically improved with HAART. Clinical presentations in HIV and non-HIV immunocompromised patients were similar...
- Geographical representativeness of published and ongoing randomized controlled trials. The example of: Tobacco consumption and HIV infection
Nizar Ahmad
INSERM, U738, Paris, France
PLoS ONE 6:e16878. 2011
..This study aimed to compare where research is conducted to where research is needed for 2 public health priorities: tobacco consumption and HIV infection...
- Impact of single centre status on estimates of intervention effects in trials with continuous outcomes: meta-epidemiological study
Aïda Bafeta
INSERM U738, Paris, France
BMJ 344:e813. 2012
..To compare estimates of intervention effects between single centre and multicentre randomised controlled trials with continuous outcomes...
- Reporting of sample size calculation in randomised controlled trials: review
Pierre Charles
INSERM, U738, Paris, France
BMJ 338:b1732. 2009
..To assess quality of reporting of sample size calculation, ascertain accuracy of calculations, and determine the relevance of assumptions made when calculating sample size in randomised controlled trials...
Evolution of disability in adults with hip arthroplasty: a national longitudinal studyAgnes Dechartres
INSERM, U738, Universite Paris 7, UFR de Medecine, AP HP Hôpital Bichat, Département d Epidémiologie, Biostatistique et Recherche Clinique, Paris, France
Arthritis Rheum 57:364-71. 2007
..To describe disability in individuals with hip arthroplasty and its evolution over 2 years compared with that in the general population, and to compare the degree of disability between subjects with recent and older hip arthroplasty...
- Reporting of corticosteroid use in systemic disease trials: evidence from a systematic review of the potential impact on treatment effect
Christian Pagnoux
INSERM U738, Universite Paris Diderot, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
Arthritis Care Res (Hoboken) 62:1002-8. 2010
..To study how corticosteroid therapy is planned and described in reports of systemic disease trials and estimate the impact of the between-arm difference in corticosteroid dose on treatment effect...
- Delphi-consensus weights for ischemic and bleeding events to be included in a composite outcome for RCTs in thrombosis prevention
Agnes Dechartres
UMR S 738, INSERM, Paris, France
PLoS ONE 6:e18461. 2011
..To weight ischemic and bleeding events according to their severity to be used in a composite outcome in RCTs in the field of thrombosis prevention...
- A single-nucleotide polymorphism in the p110beta gene promoter is associated with partial protection from insulin resistance in severely obese adolescents
Catherine Le Stunff
Department of Pediatric Endocrinology, Pôle d Endocrinologie Enfants Adultes Cochin St Vincent de Paul, APHP, Hopital Saint Vincent de Paul, Paris V University, Paris, France
J Clin Endocrinol Metab 93:212-5. 2008
..We studied the p110beta gene as a candidate gene for association with insulin resistance (IR) and fasting glycemia in severely obese children...
- Quality of reporting of bioequivalence trials comparing generic to brand name drugs: a methodological systematic review
Amélie van der Meersch
INSERM, U738, Paris, France
PLoS ONE 6:e23611. 2011
..Generic drugs are used by millions of patients for economic reasons, so their evaluation must be highly transparent...
- Preresection serum C-reactive protein measurement and survival among patients with resectable non-small cell lung cancer
Marco Alifano
Department of Thoracic Surgery, Hotel Dieu Hospital, APHP, Universite Paris Descartes, Paris, France
J Thorac Cardiovasc Surg 142:1161-7. 2011
..This study aimed to determine whether preresection serum CRP level independently predicts survival among patients with resectable non-small cell lung cancer...
- Methods of blinding in reports of randomized controlled trials assessing pharmacologic treatments: a systematic review
Isabelle Boutron
INSERM U738, Paris, France
PLoS Med 3:e425. 2006
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